The interaction between vitamin K nutriture and warfarin administration in patients with bacterial overgrowth due to atrophic gastritis

Atrophic gastritis patients have intestinal bacterial overgrowth which could produce menaquinones. The aim of this study was to evaluate the interaction between a diet low in phylloquinone and minidoses of warfarin in subjects with and without bacterial overgrowth. Subjects with atrophic gastritis (indicated by serum pepsinogen ratio) and healthy volunteers were studied while fed a restrictive phylloquinone diet and while receiving a minidose of warfarin. Coagulation times, serum osteocalcin, serum undercarboxylated osteocalcin, plasma phylloquinone, plasma K-epoxide, plasma undercarboxylated prothrombin (PIVKA)-II and urinary gamma-carboxyglutamic acid (Gla) were measured. At baseline, there were no differences between groups for any variable measured. Comparisons between baseline and post intervention in both groups, showed significant increases in circulating levels of K-epoxide, PIVKA II and undercarboxylated osteocalcin. However, no differences were observed when comparisons were made between groups. Our data do not support the hypothesis that bacterial synthesis of menaquinones in patients with bacterial overgrowth due to atrophic gastritis confers considerable resistance to the effect of warfarin.

A new imidazole alkaloid and other constituents from Pilocarpus grandiflorus and their antifungal activity

The stems of Pilocarpus grandiflorus have afforded the new imidazole alkaloid 4,6-dehydro-1,2,4,5-tetrahydro-2,5-dioxopilocarpine in addition to the 17 known compounds germanicol, β-amiryn, ocotillone, stigmast-4-en-3-one, 3β-hydroxy-stigmast-5-en-7-one, 6β-hydroxy-stigmast-4-en-3-one, β-sitosterol, scopoletin, 3-(1′,1′-dimethylallyl)-scopoletin, elisin, dictamine, 4-methoxy-2-quinolone, platydesmine, syringaresinol, syringaldehyde, syringic acid and vanillic acid. Their structures were elucidated on the basis of chemical and spectroscopic evidence. The phenolic compounds vanillic acid and syringaldehyde and the furoquinoline alkaloid platydesmine exhibited antifungal activity against Leucoagaricus gongylophorus, the symbiotic fungus of leaf-cutting ants (Atta sexdens rubropilosa). © 2005 Verlag der Zeitschrift für Naturforschung.

Política económica y planificación en América latina = Economic policy and planning in Latin America

Incluye Bibliografía

Ajuste del balance de pagos, política crediticia y control del endeudamiento externo = Balance-of-payments adjustment, credit policy and control of the external debt

Incluye Bibliografía

Industrial policy and competitiveness in open economies

Includes bibliography

Regional environmental policy and sustainable tourism development in the Caribbean

Includes bibliography

Coordination of macroeconomic policy and fiscal decentralization

Includes bibliography

Jamaican economy: problems, policy and planning

Includes bibliography

Economic considerations for social policy and the social dimension of economic policy

Analiza los principales puntos en los que el relacionamiento entre los programas sociales y sus implicaciones economicas es mas evidente. De este modo, expone que la politica social no puede ser solamente una accion compensatoria y subsidiaria del crecimiento economico, sino que el modelo economico que rija debe ser propicio para la solucion integral de los problemas socialeto

Jamaica: Economic policy and economic performance in the 1972-1980 period: an interpretation

Includes bibliography

La transferencia de tecnología y su relación con la política comercial y el fomento de las exportaciones de América Latina = The transfer of technology and its relation to trade policy and export promotion in Latin America

Incluye Bibliografía

La política económica y el sistema de precios = Economic policy and the price system

Publicado separadamente en cada idioma

Consenso latinoamericano de Viña del Mar y la política comercial = Trade policy and the Latin American consensus of Vina del Mar

Incluye Bibliografía