914 resultados para OPIATE WITHDRAWAL


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The present study aimed to evaluate the efficacy of a multivitamin and poly minerals supplemented with Panax ginseng extract (Gerovital®) on patients suffering from common physical or mental stress. The study design was controlled, parallel and double blind. Patients were randomly divided in two groups and underwent a thorough clinical and laboratory examination. Group A received placebo capsules and group B received Gerovital® capsules. In both cases, two capsules were taken daily during meals for eight weeks. Mood as well as physical activity were evaluated through a questionnaire assessing quality of life. From the 126 patients enrolled, 12 patients (8 in group A and 4 in group B) were excluded due to voluntary withdrawal, 55 patients completed the study in group A and 59 in group B. The treatment with Gerovital® significantly increased the quality of life when compared to placebo. After 15 days of study no difference between groups was observed. However, at 30th, 45th and 60th day, group B showed a statistically significant increase in average score from 30.05 to 41.96, 47.01 and finally 50.81 points. No increase in body weight was detected in either group. No difference in blood pressure or heart rate was also observed between treatments. The present study has shown that the daily use of Gerovital® over a 2-month period can be effective in improving quality of life in patients suffering from physical and mental stress among individuals of different ages, ranging from adults to elderly. Moreover, its use has been associated to a lower incidence of flu-like seasonal respiratory illnesses. Finally, the incidence of undesired effects was similar to placebo.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Sugar cane production is of the utmost importance to the economy of the entire Brazil, due to its multiple utility, being used as the raw material for the manufacture of various items, particularly, sugar and alcohol. In areas of sugarcane monoculture, the appropriate management of soils and water is essential, not only for the maintenance of the quality of the environment, but also for the quality of life of the population. Among the main impacts generated by the cultivation of sugar cane, stands out the withdrawal of the riparian forest, which is essential to the balance and maintenance of the ecosystem. Before that, the present work aimed at mapping the environmentally vulnerable areas in the basin of a tributary of the Corumbataí river, located in the district Santa Olímpia, in the city of Piracicaba-SP. For the purpose, techniques were used in Geoprocessing, aiming to produce thematic maps of Slope, for the Use and Occupation of Land, of Permanent Preservation Areas (APP), Soil and Geological of the basin of interest. From these mappings, the analysis was performed multi-criteria, which resulted in the Map of Environmental Vulnerability. This mapping environmental assessment of the study area, indicating proposals of practices for the management and conservation of soil and water resources, for the purpose of improving the environmental quality of the analyzed area. In this way, the research of this nature, may help in the decision-making on the part of the governmental bodies as well as civil society

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The Cerrado is home to important biodiversity areas in the state of Sao Paulo. Therefore, research on the reproduction of species of this biome are essential to help conservation programs. Pollination is the main mechanism by which outcrossing plants perpetuate their populations, and the attractive, such as nectar, are of vital importance to many anthophilous animals and essential to the maintenance of interactions with pollinators. In this context, the objective of this study was to investigate the ecological dynamics of secretion and sugar composition of floral nectar in Zeyheria montana, an ornithophilous exclusive Cerrado species, visited preferentially by Colibri serrirostris, also exclusive to this biome. This dynamic was assessed in isolated flowers in pre-anthesis, using microsyringes to collect nectar and manual refractometer to measure the concentration. Experiments were carried out to evaluate production throughout anthesis, including the assessment of total daily production, the effect of successive removal, the rate of production during the day and night and changes in concentration and composition of sugars, which was performed in HPLC (High Performance Liquid Chromatography). The rate of nectar production was about three times greater at night with a concentration two times lower, resulting in a supply of large amounts of dilute nectar in the early morning hours, peak of visitation for hummingbirds. Moreover, the production of nectar was more pronounced before the anthesis, and is available to visitors already in newly opened flowers, which are preferentially visited by C. serrirostris. There was an increase in the nectar production of flowers in the group with successive manual removal upon the control group, suggesting that the withdrawal by visitors stimulates the production, ensuring the availability of the resource including flowers previously visited... (Complete abstract click electronic access below)

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The project has as objective to adjust the model QUAL2K to “Ribeirão Claro” river to evaluate the behavior of OD and DBO when are simulated the following sceneries: (i) implantation of a hypothetic wastewater station treatment that treats all the effluent thrown nowadays in the body of water; (ii) increase of withdrawal flow of DAAE to public supply and (iii) increase of nowadays flow of wastewater throwing, being the two last caused for the population increasing. The results obtained allowed to conclude that the model QUAL2K presented a good adjustment to the variable OD and a reasonable adjustment to the variable DBO, being that the same was suitable to the simulation of the sceneries proposed.

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It is possible in many countries, perhaps all, there is business groups of pharmaceuticals industry, cosmetics together with the universities that use animals in scientific research and testing for the creation of new products and medicines. Currently is growing discussion about standards and criteria for the use of these animals (guinea pigs) and also increases the number of debates on ethical issues in research with animal models. This research seeks to portray the reality of the use of animals in scientific research academic at the University, specifically to research in physical education, as it has used animals in the areas of Physiology of Sport and Physical Activity, Nutrition for Athletes, among others. Initially is shown the pre-reflection, exposing the laws governing the subject, treating the animal experimentation with regard to its history and the issues of speciesism and the methodological mistake. It reveals what it is and as is the use of animals in education and the inability of the student to change that reality, to refuse to participate in the cruel activity, and even they are aware of their rights as in the case of the withdrawal of consciousness. Presents researchers and universities not use animals and ends the pre-debate showing Who is really the most animal research at the university by providing alternatives for them. We conducted a literature survey on animal experimentation, research universities, and alternative methods. The following is the phenomenon in understanding and awareness of the researchers who use animals in their research, conducting a phenomenological analysis of his speeches, revealing the meanings of their animal research. The focus of this study is, therefore, the analysis of discourses of researchers who carried out research using animal experiments (guinea pigs). The phenomenon of understanding of the researchers about their research is made clear... (Complete abstract click ectronic access below)

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Pós-graduação em Ciências Biológicas (Zoologia) - IBRC

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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We chose to do a quick presentation about the authenticity of hagiographies of Venantius Fortunatus. Then began a debate on the concept of holiness and medieval saint. After this discussion, which this author worked with two main models of holiness: the acetic-monastic and episcopal. The first model is present in hagiographies devoted to Patern and Radegund. In these descriptions abound this lifestyle choice: the pursuit of withdrawal from the world, the martyrdom, miracles and temptations related to this kind of choice. However, their hagiographies have, in most cases, the model of episcopal sanctity. In this model, the sanctity appears as a condition for becoming a bishop, and more, the miraculous virtue is clearly a feature of such positions.