999 resultados para Neoplasias da língua


Relevância:

20.00% 20.00%

Publicador:

Resumo:

O livro é um estudo fonológico da língua indígena Deni, pertencente à família Arawá e falada no estado do Amazonas por cerca de 1.200 pessoas, distribuídas por nove aldeias. Ele reveste-de de importância na medida em que, embora a língua Deni já seja conhecida há algum tempo, os estudos a seu respeito eram até agora esparsos e inconsistentes, realizados por missionários que visavam à catequese. Fruto de pesquisa de campo com falantes nativos, o livro aprofunda alguns aspectos pouco compreendidos da língua Deni, como suas relações com as outras cinco línguas da família linguística Arawá, que em sua maioria são faladas por povos amazônicos. Traz ainda uma análise fonológica preliminar que permite melhor entendimento do sistema de consoantes e vogais do Deni, assim como da constituição das sílabas e do padrão acentual. Muitas línguas indígenas brasileiras foram extintas sem deixar nenhum tipo de estudo, quando se sabe que as pesquisas realizadas sobre as línguas indígenas no mundo contribuíram enormemente para o desenvolvimento da Linguística. No Brasil, este cenário paulatinamente começa a mudar. O livro comprova que há de fato um novo interesse pela análise e documentação das línguas indígenas no país

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Baseia-se em uma pesquisa interinstitucional que focaliza o âmbito mais amplo em que são formuladas e implementadas as políticas de formação de professores no Estado de São Paulo. Tem por objetivo contribuir para a elucidação das forças presentes em movimentos de reforma curricular nos cursos de licenciatura, cotejando dados e aspectos socioculturais e institucionais circundantes. A análise incide sobre projetos pedagógicos de dois cursos de Letras de duas universidades públicas paulistas. Essas instituições desenvolveram, nos últimos anos, projetos ou ações de formação de professores para a escola básica, e é nesse contexto que se inserem os projetos pedagógicos analisados, que são tomados como exemplos de caminhos diferenciados que as universidades traçam, influenciadas pela história de cada instituição. O procedimento de pesquisa adotado foi a análise documental e o conceito de currículo em processo orientou as reflexões desenvolvidas. Reafirma-se, como em outros estudos, que a necessária integração entre saberes pedagógicos e saberes provenientes da área de referência continua sendo tarefa difícil, que as circunstâncias na criação dos cursos e a formação superposta deixou suas marcas nas instituições e que as tentativas para superá-la constituem exemplos esparsos e não modelos generalizados, o que ressalta a relevância da continuidade das pesquisas sobre o currículo dos cursos de licenciatura.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Pós-graduação em Estudos Linguísticos - IBILCE

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Human salivary gland tumors originated from intercalated ducts present a broad range of histologic and cytologic patterns, mainly due to the presence of myoepithelial cells. The aim of this study is to verify the differentiation grade of neoplastic cells and a possible relation between myoepithelial cell differentiation and the presence of luminal secretory contents. The expression of vimentin and cytokeratin (CK) intermediate filaments, actin myofilament and epithelial membrane antigen (EMA) was investigated by double labeling immunocytochemical technique, in thirty salivary gland neoplasms: 5 pleomorphic adenomas, 5 myoepitheliomas, 3 basal cell adenomas, 7 adenoid cystic carcinomas (ACC) and 10 polimorphous low grade adenocarcinomas (PLGA). Tumors with intercalated duct differentiation (pleomorphic adenomas, basal cell adenomas and ACC) express CKs 7, 8, 18 and 19 in the luminal cells and coexpress eventually CK14 with these CKs. Some luminal cells stained with anti-EMA antibody, mainly where a secretory content in the lumen was observed. Outer ductal cells and other myoepithelial-like cells express vimentin, sometimes coexpressing actin and/or CK14 with vimentin. Plasmacytoid cells in myoepitheliomas and pleomorphic adenomas express vimentin and rarely CKs 7, 8, 18 and 19, sometimes coexpressing these CKs with CK14 but they are negative for the remaining antigens. Tumors without intercalated duct differentiation (solid basal cell adenoma and PLGA) express vimentin and CKs 7, 8, 14 and 18, sometimes coexpressing CKs 8 and 18 with CK14. In conclusion, in tumors with intercalated duct differentiation, myoepithelial cells express vimentin and sometimes coexpress actin and/or CK14 with vimentin, never coexpressing other CKs with vimentin. CK14 and actin are independently expressed by myoepithelial cells, so their expression is probably induced by different stimulus. However, the secretory function of luminal cells, visualized by EMA staining, ....

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The oral cancer model in hamsters shows many simílarities with developmental oral cancer in humans. The proliferating capacity is one the most characteristics of neoplásica ce/Is and detection of these ce/Is allow us, throughout of its counting, to achieve an estimated tumour growing index, with a consequent repercussion about prognostic and in the treatment of those lesions. 40 golden Syrian hamsters, both genders, aged between two to six mouth and weight 150g in average were used. The left síde of tangue of each animal was painted for eight consecutive weeks, with a solution of DMBA. Tongues were removed, fixed in 10% buffered fonnal solution. The histological slides were stained by AgNOR technique and by PCNA and β-catenin immunohistochemical antibodies. Statistical analyzes were performed by ANOVA one-way test and Tukey test. We may conclude that an association between AgNOR and PCNA might indicate the higher proliferating activity of the analyzed celIs. The experimental carcinogenesis model in hamster tongue is an available methodology for immunohistochemistry study. And finally, PCNA and β-catenin immunohistochemical antibodies may be used to analyze possible premalignant areas in oral leukoplakia

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The article analyses three school exams of Elementary School, two belonging to a mother and one of her son, which were kept and provided to the researcher by the mother. The first two exams were dated March 30 and November 13, 1935 of the 3rd grade of Grupo Escolar Fernando Lobo in Juiz de Fora, Minas Gerais. The third one was produced at Grupo Escolar Coronel Amâncio Bueno in Jaguariúna, São Paulo in March 28, 1963 in a 4th grade class. The analysed data all together point out school products which are the result of the relationship between teacher, student and school culture. School exams are as important documents as the notebooks in order to understand the school culture, and as this paper tries to indicate, they are the means for the insertion into the world of written culture. The methodology based on the microanalysis of these documents reveals records about the structure of the exams and the Brazilian school curriculum in the teaching of Portuguese as a mother tongue in 1935 e 1963.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The aim of this study was to verify the reliability of the Brazilian Portuguese version of the instrument Cerebral Palsy: quality of life questionnaire for children: primary caregiver questionnaire (CP QOLChild: primary caregiver) translated and culturally adapted. Thus, the translation and cultural adaptation of the instrument was made, and then the procedures to verify its reliability were performed. The translated and culturally adapted questionnaire was answered by 30 caregivers of children with cerebral palsy and inter and intra-observer analysis followed. The data allowed the authors to identify an internal consistency rangering from 0.649 to 0.858, intra-observer reliability from 0.625 to 0.809 and inter-observer reliability from 0.498 to 0.903. The analysis suggests that the instrument has acceptable psychometry.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Recent years have seen a movement toward school inclusion of children with special educational needs. In Brazil, there is the formulation of laws guaranteeing rights for disabled people, giving you free access to regular classroom complemented by specialized educational services. In the case of students with deafness, the Federal Decree No. 5626 of 2005, recommends that schools offer the Brazilian sign language as language support, and should take into classrooms, an interpreter. In this study we conducted a mapping of the educational situation of students with hearing loss of 35 municipalities. There was a mode of education in which deaf students are enrolled, and also the municipalities have organized the specialized educational services for such students. Data were collected through interviews with managers of 35 municipalities. The results showed that the vast majority of municipalities participating in the study opted for the enrollment of deaf students in regular class. Only a few municipalities managers reported the existence of classes and enrollment in special schools or even the existence of deaf students out of schools. It also found that all municipalities have organized the specialized educational services, like additional offering in the resource rooms. We conclude that despite the existing difficulties, the Brazilian municipalities are gradually adjusting to the prospect of inclusive education. Continuing education courses should be offered in order to prepare more teachers to work with diversity.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The process of inclusion of deaf students at regular and specialized educational institution is a complex issue, which has the main point of discussion its specificity linguistic represented by Brazilian Sign Language. Whereupon, this research analyzed how the discourses of young students with deafness on this type of education at regular and specialized educational institution from a city situated in the State of São Paulo. The aim of this study was analyze the relations between the discourses of deaf students and their production conditionals, using the dimension of Discourse Analysis and the historical-cultural psychology. As parts of this research, were used four deaf students enrolled in schools belong in the city of São Paulo, which two schools are regular and two are specialized to deaf people. The collection instruments build themselves in observation of dialogue situations in classroom and interview semistructured. The interviews were made by video recording, researcher and an interpreter. The results showed that discourse of the student enrolled in the specialized school differs in relation to the ideals of bilingual education, in this case defended by users of the Brazilian Sign Language, fact not observed in the context of the regular school.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)