mer-(4-aminobenzenesulfonato-kappa N)triapua(1,10-phenanthroline-kappa N-2,N ')cobalt(II) chloride

Both coordination and hydrogen bonds contribute to networking in the supramolecular title compound, [Co(C6H6NO3S)(C12H8N2)(H2O)(3)]Cl, which contains a discrete [Co(C6H6NO3S)(C12H8N2)(H2O)(3)](+) complex cation, formed by one 4-aminobenzenesulfonate ligand, one 1,10-phenanthroline ligand and three coordinated water molecules, together with one uncoordinated chloride anion. These discrete cations and chloride anions are connected by hydrogen-bonding interactions into a two-dimensional supramolecular motif. Further hydrogen-bonding interactions consolidate the structural architecture and extend the two-dimensional supramolecular structure into a three-dimensional network.

A new 1D metal-organic coordination polymer with blue fluorescent emission: [Cd-2(1,10 '-phen)(2)(betc)(H2O)](n)

A new coordination polymer [Cd-2(1,10'-phen)(2)(betc)(H2O)](n) (1) (betc = benzene-1,2,4,5-tetracarboxylate, 1,10'-phen = 1,10'-phenanthroline) was hydrothermally synthesized from CdCl2.2.5H(2)O, H(4)betc and 1,10'-phen at 160 degreesC. It was characterized by IR, XPS, TG and single-crystal X-ray diffraction. Compound 1 possesses infinite chair-like chains which construct 3D framework through pi-pi interactions and the hydrogen bond interactions. The fluorescent spectrum study shows that compound 1 exhibits blue fluorescent emission in the solid at room temperature.

Synthesis, crystal structure, and thermal property of a novel supramolecular assembly: (NH42810424)(CHNO) O-[H(V)O(]2H)4(10)28(2), constructed from decavanadate and caffeine

A novel 3D supramolecular assembly constructed from decavanadate and caffeine building blocks, (NH4)(2)(C8H10N4O2)(4)[H4V10O28].2H(2)O (1), has been synthesized in aqueous solution and characterized by elemental analysis, IR, H-1 NMR, V-51 NMR, TG-DTA, and single crystal X-Ray diffraction. The compound 1 crystallizes in monoclinic system, space group P2(1)/n, a = 15.801(1) Angstrom, b = 12.914(1) Angstrom, c = 15.913(2) Angstrom, beta = 113.55degrees, V = 2976.4 (5) Angstrom(3), Z = 2, R = 0.0498 with 6818 reflections. Water molecules, ammonium ions, and caffeine act as "cement" linking the polyanions into 1D chain along the c-axis by hydrogen bonding. In compound 1, extensive hydrogen-bond contacts and strong pi-pi interactions lead to an ordered 3D supramolecular framework. TG-DTA curves indicate that the weight loss of the complex can be divided into three stages.

一个新的超分子化合物(C_(10)H_(18)N)_6As_2Mo_(18)O_(62)·6CH_3CN·8H_2O的合成、结构及性质

以Dawson型砷钼酸、金刚烷胺为原料 ,合成了一个新的超分子化合物 :(C10 H18N) 6As2 Mo18O62 ·6CH3 CN·8H2 O .通过元素分析 ,IR ,1HNMR等方法对合成的化合物进行了表征 .X射线衍射晶体解析表明 ,金刚烷胺与Dawson型多阴离子以静电力和分子间力 (氢键 )结合 ,并且在新化合物中 ,金刚烷胺及多阴离子结构基本保持不变 .该化合物均具有可逆的光致变色特性 ,基于变色后样品的电子自旋共振 (ESR)谱提出一个可能变色机理 .以该类化合物为修饰剂的本体修饰碳糊电极(APM CPE)对过氧化氢还原有很好的电催化活性.

Computer simulation of Gd(III) speciation in human interstitial fluid

The speciation and distribution of Gd(III) in human interstitial fluid was studied by computer simulation. The results show that at the background concentration, all the Gd(III) species are soluble and no precipitates appear. However as the total concentration of Gd(III) rises above 2.610 x 10(-9) mol/l the insoluble species become predominant. GdPO4 is formed first as a precipitate and then Gd-2(CO3)(3). Among soluble species, free Gd(III), [Gd(HSA)], [Gd(Ox)] and the ternary complexes of Gd(III) with citrate as the primary ligand are main species when the total concentration of Gd(III) is below 2.074 x 10(-2) mol/l. With the total concentration of Gd(III) further rising, [Gd-3(OH)(4)] begins to appear and gradually becomes a predominant species.

Characterization of prolidase activity using capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection and application to evaluate collagen degradation in diabetes mellitus

A new method for prolidase (PLD, EC 3.4.13.9) activity assay was developed based on the determination of proline produced from enzymatic reaction through capillary electrophoresis (CE) with tris(2,2'-bipyridyl)ruthenium(11) [Ru(bpy)(3)(2+)] electrochemiluminescence detection (ECL). A detection limit of 12.2 fmol (S/N = 3) for proline, corresponding to 1.22 x 10(-8) units of prolidase catalyzing for 1 min was achieved. PLD activity determined by CE-ECL method was in agreement with that obtained from the classical Chinard's one. CE-ECL showed its powerful resolving ability and selectivity as no sample pretreatmentwas needed and no interference existed. The clinical utility of this method was successfully demonstrated by its application to assay PLD activity in the serum of diabetic patients in order to evaluate collagen degradation in diabetes mellitus (DM). The results indicated that enhanced collagen degradation occurred in DM.

Synthesis and characterization of soluble oligo (9,10-bisalkynylanthrylene)s

Soluble oligo(9,10-bialkynylanthryiene)s up to pentamers were synthesized by means of the Suzuki coupling reaction. A solution processed thin film field-effect transistor from pentamer OA-5b shows a charge carrier mobility of 2.95 x 10(-3) cm(2)/V center dot s.

Kinetic study of paracetamol on prolidase activity in erythrocytes by capillary electrophoresis with Ru(bpy)(3)(2+) electrochemiluminescence detection

We explored the CE with Ru(bpy)(3)(2+) electrochemiluminescence detection for the kinetic study of drug-enzyme interaction. Effects of four nonsteroidal anti - inflammatory drugs including aspirin, paracetamol, sodium salicylate and phenacetin on prolidase (PLD) activity in erythrocytes were investigated. Aspirin enhanced PLD activity whereas the other three had inhibiting effects. This may reveal their different effects on the collagen biosynthesis and catabolism that influence tumor invasiveness. Kinetic study of paracetamol on PLD showed that the value of Michaelis constant Km for PLD was 1.23 mM. The mechanism of PLD inhibition by paracetamol is noncompetitive inhibition, and the inhibitor constant K-i value obtained in our research was 9.73 x 10(3) mu g/L.

Tetraaqua(1,10-phenanthroline-kappa(2) N, N ')copper(II)naphthalene-1,5-disulfonate dihydrate

In the title structure, [Cu(C12H8N2)(H2O)(4)](C10H6S2O6)center dot-2H(2)O, the cation lies on a crystallographic twofold rotation axis and the anion lies on a centre of inversion. The Cu-II atom is coordinated by two N atoms of a 1,10-phenanthroline ligand and four O atoms from four water ligands in a distorted octahedral geometry. The unique Cu-O distances are 2.054 (2) and 2.088 (2) angstrom and the Cu-N distance is 2.073 (2) angstrom. In the crystal structure, a three-dimensional supramolecular framework is constructed by extensive intermolecular O-H center dot center dot center dot O hydrogen bonds.

catena-Poly[[[2-(2-furyl)-1H-imidazo[4,5-f][1,10]phenanthroline]zinc(II)]-mu-benzene-1,2-dicarboxylato]

In the title compound, [Zn(C8H4O4)(C17H10N4O)](n), the Zn-II atom is five-coordinated by two N atoms from the phenanthro-line-derived ligand and three O atoms from one bidentate and one monodentate benzene-1,2-dicarboxylate (1,2-BDC) dianions in a distorted trigonal-bipyramidal geometry. The Zn-II atoms are bridged by the 1,2-BDC ligands to form a single-chain structure. Neighboring chains interact through pi-pi interactions, leading to a two-dimensional network.

Computer simulation of Zn(II) speciation and effect of Gd(III) on Zn(II) speciation in human blood plasma

The speciation and distribution of Zn(II) and the effect of Gd(III) on Zn(II) speciation in human blood plasma were studied by computer simulation. The results show that, in normal blood plasma, the most predominant species of Zn(II) are [Zn(HSA)] (58.2%), [Zn(IgG)](20.1%), [Zn(Tf)] (10.4%), ternary complexes of [Zn(Cit)(Cys)] (6.6%) and of [Zn(Cys)(His)H] (1.6%), and the binary complex of [Zn(CYS)(2)H] (1.2%). When zinc is deficient, the distribution of Zn(II) species is similar to that in normal blood plasma. Then, the distribution changes with increasing zinc(II) total concentration. Overloading Zn(II) is initially mainly bound to human serum albumin (HSA). As the available amount of HSA is exceeded, phosphate metal and carbonate metal species are established. Gd(III) entering human blood plasma predominantly competes for phosphate and carbonate to form precipitate species. However, Zn(II) complexes with phosphate and carbonate are negligible in normal blood plasma, so Gd(III) only have a little effect on zinc(II) species in human blood plasma at a concentration above 1.0x10(-4) M.

4,7-(氯磺酸基苯基)-1,10-菲啰啉-2,9-二羧酸-铕标记甲胎蛋白抗体

在合成BCPDA基础上 ,对甲胎蛋白抗体与BCPDA连接及与铕离子螯合条件进行了研究。BCPDA与甲胎蛋白抗体反应后 ,分离纯化最佳淋洗液为pH9.1的0.1mol/L碳酸盐缓冲溶液 ,BCPDA用量为甲胎蛋白抗体量 (mol)的120～160倍;反应时间为30min。讨论了Eu3+ BCPDA AFP抗体螯合物的荧光光谱 ,最佳温育时间为60min,体系pH值为7.8的Tris HCl溶液。当Eu3+ 浓度为10-6mol/L时,BCPDA的检出限为4.3×10-11mol/L。

BaMgAl_(10)O_(17)∶R~(2+)(R=Eu,Mn)的真空紫外光谱特性

采用高温固相反应法合成了BaMgAl10 O17∶R(R =Eu ,Mn)荧光体 ,测量了荧光体的真空紫外激发光谱和相应的发射光谱 ,观察到基质吸收带位于 16 5nm附近 ,Mn2 + 离子的吸收位于 170～ 2 40nm范围 ,Eu2 + 离子的 4f→ 5d吸收位于 2 10～ 40 0nm范围。真空紫外光谱特性的研究表明基质与激活离子之间存在较好的能量传递。

A two-dimensional molybdenum (V) phosphate with covalently bonded transition metal coordination complexes: hydrothermal synthesis and structure characterization of Na-2[{Mn(phen)(2)(H2O)}{Mn(phen)(2)}(3){Mn (Mo12O24)-O-V (HPO4)(6)(PO4)(2)(OH)(6)}] center dot 4H(2)O (phen=1,10-phenanthroline)

An organic-inorganic hybrid molybdenum phosphate, Na-2[{Mn(phen)(2)(H2O)} {Mn(phen)(2)}(3){(MnMo12O24)-O-v (HPO4)(6)(PO4)(2) (OH)(6)}] . 4H(2)O (phen=1,10-phenanthroline), involving molybdenum present in V oxidation state and covalently bonded transition metal coordination complexes, has been hydrothermally synthesized and structurally characterized by single-crystal X-ray diffraction. Deep brown-red crystals are formed in the triclinic system, space group P (1) over bar, a=16.581(l)Angstrom, b=18.354(1)Angstrom, c=24.485(2)Angstrom, alpha=80.589(l)degrees, beta=71.279(1)degrees, gamma=67.084(1)degrees, V=6493.8(8)Angstrom(3), Z=2, lambda(MoKalpha)=0.71073Angstrom (R(F)=0.0686 for 29,053 reflections). Data were collected on a Bruker Smart Apex CCD diffractometer at 293 K in the range of 1.76 < theta < 28.06degrees using omega-2theta scans technique. The structure of the title compound may be considered to be based on {Mo6O12(HPO4)(3)(PO4)(OH)(3)} units bonded together with {Mn(phen)(2)} subunits into a two-dimensional network. Two types of tunnels are observed in the solid of the title compound.

新型笼状同多钒酸盐[Ni(1,10′-phen)_3]_2·[V_2~ⅣV_8~ⅤO_(26)]的水热合成和晶体结构

尽管多金属氧酸盐 (POMs)的研究已有180多年的历史,但大量的POMs结构在最近几十年才被陆续解析出来[1～4].其中 ,同多钒酸盐由于钒配位几何形状的多样性,结构最为丰富 ,例如:[V4 O12 ]4-[5],[V5O14 ]3-[6],[V10 O2 8]6-[7] ,[V15O4 2 ]9-[8],[V13 O3 4 ]3-[9].值得注意的是,在这些化合物中,钒的化合价均处于最高氧化态+5价.由于+4价钒不易在溶液中(尤其是水中)稳定存在,因此在以往的常压溶液合成中具有混合价态的同多钒酸盐报道很少.与饱和价态的同多钒酸盐相比,混价多钒酸盐具有更为新奇的电荷分布和拓扑学几何构型,并且在 POMs的理论研究和抗病毒药物、电存储材料以及磁性材料等应用领域有特殊的研究和开发价值[1,10,11].因此,制备具有混价的新型同多钒酸盐一直倍受关注.近年来,水热合成技术的引入使同多钒酸盐合成化学迅速发展.水热体系提供了一个特殊的反应环境 [12 ],使制备各种具有混合价态的同多钒酸盐成为可能.Müller等[13]对这一领域开...