Review of the synthesis of layered double hydroxides: a thermodynamic approach

The synthesis of layered double hydroxides (LDHs) by hydrothermal-LDH reconstruction and coprecipitation methods is reviewed using a thermodynamic approach. A mixture model was used for the estimation of the thermodynamics of formation of LDHs. The synthesis and solubility of LDHs are discussed in terms of standard molar Gibbs free energy change of reaction. Data for numerous divalent and trivalent metals as well as for some monovalent and tetravalent metals that may be part of the LDH structure have been compiled. Good agreement is found between theoretical and experimental data. Diagrams and tables for the prediction of possible new LDH materials are provided.

Desviaciones al modelo logarítmico-lineal en la solubilidad de ibuprofén y naproxén en mezclas cosolventes propilenoglicol-agua

The deviations observed in the solubility of ibuprofen (IBP) and naproxen (NAP) in propylene glycol (PG) + water (W) cosolvent mixtures with respect to the logarithmic-linear model proposed by Yalkowsky have been analyzed at 25.00 ± 0.05 ºC. Negative deviations were obtained in all cosolvent compositions for both drugs; they were greater for IBP. Another treatment, based on Gibbs free energy relationships, was also employed showing an apparent hydrophobicity chameleonic effect, because at low PG proportions NAP is more hydrophobic, whereas at high PG proportions IBP is more hydrophobic. The results are discussed in terms of solute-solvent and solvent-solvent interactions.

Electrooxidación de glifosato sobre electrodos de níquel y cobre

The electrochemical oxidation of glyphosate on an electrode of nickel and on one of copper was studied. With both electrodes electrochemical signals related to the glyphosate concentration were observed. However, the behaviour of the copper electrode was much better than that of the nickel electrode. A calibration curve was obtained of the electrical signal of this electrode as a function of the glyphosate concentration. The detection limit was 30 µM. In the case of nickel, an increase in the oxidation signal, which is related to the glyphosate concentration, was obtained. However, the results were less reproducible and additional information is necessary to propose an interaction mechanism between glyphosate and the electrode.

Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff

The dissolution enthalpy (ΔH0soln) of sodium sulfacetamide in water was determined by means of isoperibolic solution calorimetry. It was found that ΔH0soln diminishes as the drug concentration increases. Otherwise, the calorimetric values obtained as a function of the drug concentration were significantly different than those predicted by the van't Hoff method. It was demonstrated that the later is not a fully reliable method for the determination of ΔH0soln values in the specific case of highly soluble sodium salts. The observed phenomenon could be explained by the presence of strong solute-solute interactions at high salt concentrations, in addition to solute-solvent and solvent-solvent interactions.

Isolamento e identificação da morina em mel brasileiro de Apis mellifera

The flavonoid fraction was purified by a combination of chromatography on Amberlite XAD-2 and preparative silica gel TLC. Morin (3, 5, 7, 2', 4'- pentahydroxyflavone) was the only flavonol found in honey from Brazilian Citrus sp.. The structure of morin was determined on the basis of UV and ¹H and 13C NMR spectral data together with literature references. This is the first report on the isolation of morin from Brazilian Citrus honey.

De la metodologia a la pràctica : anàlisi de les metodologies d'ensenyament musical i elaboració d'una proposta metodològica per a la pràctica docent en l'àmbit del llenguatge musical a les escoles de música

Aquest treball vol ser una revisió d'algunes de les principals metodologies desenvolupades al llarg del segle XX per l'ensenyament del llenguatge musical. Aquesta revisió serà completada amb una anàlisi comparada de les visions filosòfiques i els objectius didàctics de les diferents propostes, d'on extreure unes conclusions per a una possible nova proposta didàctica. Les metodologies que s'analitzen són les dels següents autors: Émile Jaques-Dalcroze, Carl Orff, Zoltán Kodály, Edgar Willems i Maurice Martenot.

Un sistema para la deteccion de antioxidantes volatiles comunmente emitidos desde especias y hierbas medicinales

An apparatus which allows the direct measurement of the antioxidant capacity of volatiles compounds emitted from some herbs and culinary spices is described. The device comprises: a sample chamber, a mixing chamber, a pump and, a detection system. Volatiles from Clove (Syzygium aromaticum (L.) Merr. & L.M. Perry) were purged and captured into a DPPH-containing solution and changes in the absorbance were recorded on-line. Linear response was observed when temperature was set between 30-53 ºC; nitrogen flow was 15 mL min-1 during 60 min; DPPH concentration was 20 µmol L-1 and a sample size (powdered Clove) ranged between 200-1000 mg.

En physico-oeconomisk beskrifning öfwer Hwittis sokn

Invocatio: I.G.N.

Biosilicato®: histórico de uma vitrocerâmica brasileira de elevada bioatividade

This paper presents a historical of the Biosilicate®, a bioactive glass-ceramic developed at the Vitreous Materials Laboratory of the Federal University of São Carlos, Brazil. After decades of study accomplished with bioactive glasses and glass-ceramics, Biosilicate® results from a natural evolution and has similar bioactivity index, but far superior mechanical properties than of all bioactive glasses. Biosilicate® is almost fully crystalline and also exhibits much higher bioactivity than all the currently commercially available bioactive glass-ceramics. Due to its special characteristics, Biosilicate® has been successfully tested for several medical and dental applications as we thoroughly discuss in this review paper.

Desenvolvimento de tecnologia para confecção de eletrodos e conjuntos eletrodo-membrana-eletrodo (MEA) por impressão à tela para aplicação em módulos de potência de células PEMFC

Significant functions in the Proton Exchange Membrane Fuel Cells (PEMFCs) rely on Gas Diffusion Layers (GDLs), such as control the water balance in the membrane electrode assembly (MEA), allow suitable gas permeability and porosity, etc. Aware of the GDL importance in the cell performance and its great demand in scale-up projects, the fuel cell research group at Instituto de Pesquisas Energéticas e Nucleares (IPEN) has developed a Sieve Printing method (innovative in Brazil) as a strategic solution for producing GDL and electrodes used in high power PEMFC stacks. The method has shown to be adequate to fabricate low cost electrodes, GDLs of different dimensions and to produce any amount of MEAs for power stacks.

Interactions of chitosan/genipin hydrogels during drug delivery: a QSPR approach

A hydrogel comprised of chitosan crosslinked using the low-toxicity crosslinker genipin was prepared, and the absorption of glibenclamide by the hydrogel was investigated. Optimized structures and their molecular electrostatic potentials were calculated using the AM1 method, and the results were used to evaluate the molecular interactions between the three compounds. The quantitative structure-property relationship model was also used to estimate the activity of the chemicals on the basis their molecular structures. In addition, theoretical Fourier transform infrared spectra were calculated to analyze the intermolecular interactions in the proposed system. Finally, the hydrophilicity of the hydrogel and its influence on the absorption process were also estimated.

Observações críticas acerca da noção Leibniziana de decretos divinos possíveis

Este artigo apresenta, em primeiro lugar, uma reconstrução conceitual das razões que levam Leibniz, em sua correspondência com Arnauld, a introduzir o conceito de decretos divinos possíveis. Em um segundo momento, o artigo desenvolve alguns argumentos para demonstrar que a introdução desse conceito torna inconsistente a arquitetônica global da metafísica leibniziana.

Possibilidade, compossibilidade e incompossibilidade em Leibniz

O presente artigo tem por objetivo tornar claro que há um problema referente à origem da incompossibilidade na metafísica de Leibniz, fornecendo, em um segundo momento, uma resposta ao problema.

Leibniz acerca de almas, corpos, agregados e substâncias na discussão com Fardella (1690)

Defendo neste artigo, contra a interpretação de Robert Adams, a tese de que, na discussão com Fardella (1690), Leibniz adota uma ontologia realista, segundo a qual seres vivos, e não almas, são substâncias.

A interdisciplinaridade no ensino médico

Este artigo discute a interdisciplinaridade no ensino médico, reconhecendo que as denúncias sobre a fragmentação deste ensino e a ênfase disciplinar na conformação do projeto pedagógico, centrada em concepções biologicistas e visões especializadas, intensificam-se frente aos processos de consolidação das reformulações curriculares dos cursos de graduação em Medicina. A partir de um rastreamento conceitual sobre interdisciplinaridade, privilegiando as interlocuções com Morin, Fazenda, Fourez, Pombo e Furlanetto, analisa-se a existência de múltiplos olhares e compreensões sobre o seu significado. Construir caminhos no ensino médico a partir da interdisciplinaridade inclui a implementação de desenhos curriculares que possibilitem a articulação de conteúdos, valorizem o enfoque problematizador e desenvolvam atividades acadêmicas que tenham como eixos a prática médica no contexto do trabalho em saúde, a inserção do estudante e do professor como sujeitos, a produção contextualizada de saberes. Delineiam-se desafios e possibilidades para a construção de propostas formativas que empreendam práticas interdisciplinares frente à complexidade das dinâmicas de ensinar, aprender e cuidar em Medicina.