Os registros não-convencionais da coda nasal em dados de EJA

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A escrita de /an/ por pré escolares: pistas acústico-auditivas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A complexidade da coda silábica na escrita de pré-escolares

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Maternal Thyroid and Glucocorticoid Hormone Interactions in Larval Fish Development, and Their Applications in Aquaculture

Thyroid hormones (THs) have long been known to have regulatory roles in the differentiation and maturation of vertebrate embryos, beginning with the knowledge that hormones of maternal origin are essential for human fetal central nervous and respiratory system development. Precise measurements of circulating THs led to insights into their critically important actions throughout vertebrate growth and development, initially with amphibian metamorphosis and including embryogenesis in fishes. Thyroid cues for larval fish differentiation are enhanced by glucocorticoid hormones, which promote deiodinase activity and thereby increase the generation of triiodothyronine (T-3) from the less bioactive thyroxin (T-4). Glucocorticoids also induce the expression of thyroid hormone receptors in some vertebrates. Maternally derived thyroid hormones and cortisol are deposited in fish egg yolk and accelerate larval organ system differentiation until larvae become capable of endogenous endocrine function. Increases in the T-3/T-4 ratio during larval development may reflect the regulatory importance of maternal thyroid hormones. Experimental applications of individual hormones have produced mixed results, but treatments with combinations of thyroid and corticoid hormones consistently promote larval fish development and improve survival rates. The developmental and survival benefits of maternal endocrine provisioning are increased in viviparous fishes, in which maternal/larval chemical contact is prolonged. Treatments with exogenous thyroid and corticoid hormones consistently promote development and reduce mortality rates in larval fishes, with potential hatchery-scale applications in aquaculture.

Feeding, body condition and reproductive investment of Astyanax intermedius (Characiformes, Characidae) in relation to rainfall and temperature in a Brazilian Atlantic Forest stream

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Tissue-engineering-based Strategies for Regenerative Endodontics

Stemming from in vitro and in vivo pre-clinical and human models, tissue-engineering-based strategies continue to demonstrate great potential for the regeneration of the pulp-dentin complex, particularly in necrotic, immature permanent teeth. Nanofibrous scaffolds, which closely resemble the native extracellular matrix, have been successfully synthesized by various techniques, including but not limited to electrospinning. A common goal in scaffold synthesis has been the notion of promoting cell guidance through the careful design and use of a collection of biochemical and physical cues capable of governing and stimulating specific events at the cellular and tissue levels. The latest advances in processing technologies allow for the fabrication of scaffolds where selected bioactive molecules can be delivered locally, thus increasing the possibilities for clinical success. Though electrospun scaffolds have not yet been tested in vivo in either human or animal pulpless models in immature permanent teeth, recent studies have highlighted their regenerative potential both from an in vitro and in vivo (i.e., subcutaneous model) standpoint. Possible applications for these bioactive scaffolds continue to evolve, with significant prospects related to the regeneration of both dentin and pulp tissue and, more recently, to root canal disinfection. Nonetheless, no single implantable scaffold can consistently guide the coordinated growth and development of the multiple tissue types involved in the functional regeneration of the pulp-dentin complex. The purpose of this review is to provide a comprehensive perspective on the latest discoveries related to the use of scaffolds and/or stem cells in regenerative endodontics. The authors focused this review on bioactive nanofibrous scaffolds, injectable scaffolds and stem cells, and pre-clinical findings using stem-cell-based strategies. These topics are discussed in detail in an attempt to provide future direction and to shed light on their potential translation to clinical settings.

Positive effects of auditory cue in locomotor pattern of people with Parkinson's disease (off and on medication)

Gait disorders are identified in people with Parkinson’s disease. The aim of this study was to investigate the effect of auditory cues and medication on kinematic, kinetic and EMG parameters, during different gait phases of people with PD and healthy elderly. Thirty subjects distributed in two groups (Group 1, PD patients off and on medication; Group 2, healthy elderly) participated in this study and were instructed to walk in two experimental conditions: non-cued and cued. Therefore, kinematic, kinetic and electromyography analyses were utilized to investigate the locomotor pattern. Changes in locomotor pattern (greater muscular activity) with auditory cue were observed for PD patients. Regarding the medication, locomotor parameter improvement was observed after levodopa intake in association with the auditory cue. These results confirm the hypothesis about the external cues therapy that could be used as a complement to drug therapy to achieve improvement in the locomotor pattern of PD patients.

Análise cinemática da marcha livre e adaptativa de pacientes com doença de Parkinson e idosos sadios: efeito da dica auditiva

Disorders in gait are identified in Parkinson’s disease patients. As a result, the capacity of walking independently and the interaction with the environment can be impairment. So, the auditory cues have been utilized as a non-pharmacological treatment to improve the locomotor impairment of the PD patients. However, these effects were observed in the regular lands and it’s not known the effects of auditory cues in gait during avoidance obstacles that could be more threaten for these patients. Yet, few studies in the literature compare the Parkinson’s disease patients with the older adults during the locomotor tasks and obstacle avoidance in association with the effects of auditory cues. The aim of the study is to compare the effects of the auditory cues in the gait and during obstacle avoidance in PD patients and older adults. 30 subjects distributed in two groups (Group 1 - 15, Parkinson’s disease patients; Group 2 - 15, healthy older adults) are going to participate of this study. After the participation approval, the assessment of clinical condition will be done by a physician. So, to investigate the locomotor pattern, it will be done a kinematic analysis. The experimental task is to walk on 8 m pathway and 18 trials will be done (6 for the free gait and 12 for adaptive gait). For the adaptive gait, two different obstacle heights will be manipulated: high obstacle (HO) and low obstacle (LO). In order to verify possible differences between the groups and the experimental condition, multivariance tests will be used with a significance level of 0.05. MANOVA revealed effect of condition and task. Thus, with DA, we observed an increase in cadence and reduced single support and stride length. When the tasks were compared, it was observed that the LO task, subjects had lower velocity and stride length... 9Complete abstract click electronic access below)

Estabelecimento do contraste entre as fricativas por crianças com transtorno fonológico: manipulação de pistas acústicas

The present study focuses on the presence of covert contrasts in the speech of children with a phonological disorder. The hypothesis is that children with phonological disorders manipulate secondary acoustic cues in an attempt to distinguish the phonological contrasts. We used five audio recordings of the speech of five children with speech disorders, between four and five years of age, who showed the so-called “phonic substitution” involving the sound group of the fricatives. The data were edited and analyzed using the software PRAAT. A phonetic transcription of the first repetition of each child was performed by three evaluators, reaching a 66% agreement level. After the transcription, we carried out a contrastive phonological analysis of the production of the five children and, finally, an acoustic analysis of all the “substitutions”, based on six parameters. We discovered the existence of covert contrasts in the productions auditorily regarded as homophones by the evaluators, representing a total of 54% of total substitutions identified through an impressionistic approach by the evaluators. Children with phonological disorders are seen to rely on secondary acoustic cues in an attempt to distinguish fricative phonemes. The data obtained in this study allow us to reflect on the importance of considering the phonetic detail within the phonological models.

Preferential consumption of larger fruits of Piper arboreum (Piperaceae) by Carollia perspicillata (Phyllostomidae) in the Brazilian tropical dry forest

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Adaptation of sensorimotor coupling in postural control Is impaired by sleep deprivation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Desempenho perceptivo-auditivo de crianças na identificação de contrastes fonológicos entre as oclusivas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influência da infecção por patógenos na escolha química de parceiros em tilápia-do-Nilo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O competidor interespecífico pode alterar a agressividade intraespecífica? um estudo com caranguejos do gênero Uca

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O fogo quebra a dormência e aumenta a germinação de espécies de cerrado?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)