Alendronato de sódio: metodologias para análise quantitativa

This paper presents a review of some published proposals for the analysis of sodium alendronate. The drug is an aminobisphosphonate compound used to inhibit the osteoclastic resorption of bone, and different methods were developed for its quantitative determination. These methodologies employed reversed-phase or ion-exchange HPLC analysis, both associated with different detectors: UV and fluorescence detection after derivatization of the drug, conductivity and refractive index detectors, as well as the indirect UV detection. Titrimetry and spectrophotometry (with previous complexation of the drug), which are simpler procedures, were also described, but they showed poor specificity when compared to liquid chromatography.

Ambient intelligence application based on environmental measurements performed with an assistant mobile robot

This paper proposes the use of an autonomous assistant mobile robot in order to monitor the environmental conditions of a large indoor area and develop an ambient intelligence application. The mobile robot uses single high performance embedded sensors in order to collect and geo-reference environmental information such as ambient temperature, air velocity and orientation and gas concentration. The data collected with the assistant mobile robot is analyzed in order to detect unusual measurements or discrepancies and develop focused corrective ambient actions. This paper shows an example of the measurements performed in a research facility which have enabled the detection and location of an uncomfortable temperature profile inside an office of the research facility. The ambient intelligent application has been developed by performing some localized ambient measurements that have been analyzed in order to propose some ambient actuations to correct the uncomfortable temperature profile.

Pré-concentração de cádmio com Saccharomyces cerevisiae e determinação em águas fluviais usando espectrometria de emissão óptica com plasma indutivamente acoplado

A preconcentration method based on the use of Saccharomyces cerevisiae as sorbent material is proposed for the determination of Cd(II) in river water. The solid phase extraction was performed in batch mode and the determination of the analyte in the solid phase was easily carried out by introducing a slurry of the yeast (0.0625 g / 2.5 mL) directly into the ICP OES. A limit of detection of 0.11 µg L-1 and a sample throughput in the range of 4 - 54 sample h-1 were obtained. Determinations of cadmium in a certified sample and in real river water samples were in excellent agreement with the expected values.

Dispositivo y método para medir magnitudes eléctricas de sensores analógicos

La presente solicitud de patente tiene por objeto un dispositivo y método para medir magnitudes eléctricas de sensores analógicos, que 10 incorpora notables innovaciones y ventajas.La presente invención se refiere, en general, a los sistemas de medida de sensores analógicos, incluidos aquellos que generan directamente una corriente o una tensión eléctrica.

Recuperação de cádmio de baterias níquel-cádmio via extração seletiva com tributilfosfato (TBP)

This work describes a recovery process of cadmium from spent nickel-cadmium batteries by a new hydrometallurgical route based on the selective extraction in hydrochloric acid medium with tributylphosphate (TBP), alone or dissolved in kerosene. The best results were obtained when TBP concentration was at least 75 vol%. Nickel extraction was negligible under these conditions. It was isolated after processing the rafinate through an anionic ion-exchange column. Final wastes generated are basically sodium chloride solutions, with no turbidity, color or heavy metals present in significant amounts.

Estudo da capacidade de complexação e sua relação com algumas variáveis ambientais em cinco represas do Rio Tietê/Brasil

The copper and cadmium complexation properties in natural sediment suspensions of reservoirs of the Tietê River were studied using the solid membrane copper and cadmium ion-selective electrodes. The complexation and the average conditional stability constants were determined under equilibrium conditions at pH=6.00 ± 0.05 in a medium of 1.0 mol L-1 sodium nitrate, using the Scatchard method. The copper and cadmium electrodes presented Nernstian behavior from 1x10-6 to 1x10-3 mol L-1 of total metal concentration. Scatchard graphs suggest two classes of binding sites for both metals. A multivariate study was done to correlate the reservoirs and the variables: complexation properties, size, total organic carbon, volatile acid sulfide, E II and pH.

Composição química de um resíduo alcalino da indústria de papel e celulose (DREGS)

Dregs is an alkaline solid by-product generated in the cellulose manufacturing industry that could be used to correct soil acidity. The present study aimed to evaluate the chemical composition of this product and some of its properties. The dregs presented 354 g kg-1 of calcium, neutralization capacity of 80.3%, and pH 10.7, besides low concentration of sodium (10.2 g kg-1), lead (62.9 mg kg-1) and cadmium (5.6 mg kg-1). Thus, it is a product that can safely be used to increase the soil pH.

Control d'il·luminació i ventilació d'un pàrquing

El treball presentat ve motivat per la necessitat d’instal•lació d’un pàrquing públic i privat de nova construcció a nivell d’il•luminació i ventilació. Per poder satisfer les necessitats del nostre client d’estalvi energètic i confort en l’edifici es decideix d’implementar una instal•lació immòtica que és l’aplicació de tècniques de gestió i control automatitzat a un edifici terciari amb bus de comunicació KNX/EIB. Per a la il•luminació s’han utilitzat fluorescents amb balasts DALI, que permeten la seva regulació i control, per així poder adequar en tot moment l’encesa i intensitat de llum d’aquests. En quant a la ventilació s’han utilitzat variadors de freqüència per també poder optimitzar el funcionament dels ventiladors podent posar-los en marxa quan realment sigui necessari i a la potència que calgui. Per enllaçar tots els elements de la instal•lació, detectors i actuadors, sorgeig la necessitat d’implementar xarxes de comunicació com el KNX/EIB, DALI, Modbus i Ethernet. Per gestionar variables, comunicacions i controlar elements, s´hi han implementen dos autòmats programables a més d’un PC integrat per la visualització i el control del pàrquing. S’ha aconseguit de realitzar un pàrquing totalment automàtic on no és necessaria l’actuació dels operaris i amb les principals càrregues elèctriques totalment regulables en potència. S’ha comprovat que la instal•lació funciona per sota de la potència nominal de les càrregues amb l’estalvi energètic que això suposa.

The Detector Control Systems for the CMS Resistive Plate Chamber at LHC

The RPC Detector Control System (RCS) is the main subject of this PhD work. The project, involving the Lappeenranta University of Technology, the Warsaw University and INFN of Naples, is aimed to integrate the different subsystems for the RPC detector and its trigger chain in order to develop a common framework to control and monitoring the different parts. In this project, I have been strongly involved during the last three years on the hardware and software development, construction and commissioning as main responsible and coordinator. The CMS Resistive Plate Chambers (RPC) system consists of 912 double-gap chambers at its start-up in middle of 2008. A continuous control and monitoring of the detector, the trigger and all the ancillary sub-systems (high voltages, low voltages, environmental, gas, and cooling), is required to achieve the operational stability and reliability of a so large and complex detector and trigger system. Role of the RPC Detector Control System is to monitor the detector conditions and performance, control and monitor all subsystems related to RPC and their electronics and store all the information in a dedicated database, called Condition DB. Therefore the RPC DCS system has to assure the safe and correct operation of the sub-detectors during all CMS life time (more than 10 year), detect abnormal and harmful situations and take protective and automatic actions to minimize consequential damages. The analysis of the requirements and project challenges, the architecture design and its development as well as the calibration and commissioning phases represent themain tasks of the work developed for this PhD thesis. Different technologies, middleware and solutions has been studied and adopted in the design and development of the different components and a big challenging consisted in the integration of these different parts each other and in the general CMS control system and data acquisition framework. Therefore, the RCS installation and commissioning phase as well as its performance and the first results, obtained during the last three years CMS cosmic runs, will be

Fitodisponibilidad de Cd en suelo de diferente pH tratado con lodo albañal estimada por método isotópico y extracción química

The Cd phytoavailability in sewage sludge-amended soils of different pHs using the 109Cd L-value isotopic method and Cd extracted by DTPA has been determined. Maize plants (Zea mais L.) were grown under greenhouse conditions in a xanthic ferralsol at different pHs amended with five sewage sludge (SS) rates, and labeled with 74 kBq kg-1 of 109Cd. The SS rates altered the properties of the soil chemicals and these influenced the isotopic parameter (L-value) and percent of Cd uptake by plants from soil (%Cdpdfs) and SS (%CdpdfSS). L-values and Cd extracted by DTPA correlate significantly with SS rates and Cd uptake by plants and are efficient for predicting the Cd phytoavailability in the sewage sludge-amended soil.

Low dark count geiger mode avalanche photodiodes fabricated in conventional CMOS technologies

Avalanche photodiodes operated in the Geiger mode present very high intrinsic gain and fast time response, which make the sensor an ideal option for those applications in which detectors with high sensitivity and velocity are required. Moreover, they are compatible with conventional CMOS technologies, allowing sensor and front-end electronics integration within the pixel cell. Despite these excellent qualities, the photodiode suffers from high intrinsic noise, which degrades the performance of the detector and increases the memory area to store the total amount of information generated. In this work, a new front-end circuit that allows low reverse bias overvoltage sensor operation to reduce the noise in Geiger mode avalanche photodiode pixel detectors is presented. The proposed front-end circuit also enables to operate the sensor in the gated acquisition mode to further reduce the noise. Experimental characterization of the fabricated pixel with the conventional HV-AMS 0.35µm technology is also presented in this article.

Determination of Cd and Pb in fuel ethanol by filter furnace electrothermal atomic absorption spectrometry

A method was developed for quantification of Cd and Pb in ethanol fuel by filter furnace atomic absorption spectrometry. Filter furnace was used to eliminate the need for chemical modification, to stabilize volatile analytes and to allow the application of short pyrolysis step. The determinations in samples were carried out against calibration solutions prepared in ethanol. Recovery tests were made in seven commercial ethanol fuel samples with values between 90 and 120%. Limits of detection were 0.1 µg L-1 for Cd and 0.3 µg L-1 for Pb. Certified water samples (APS 1071, APS 1033, NIST 1643d, NIST 1640) were also used to evaluate accuracy and recoveries from 86.8% to115% were obtained.

Determinação de isotiocianato de benzila em Carica papaya utilizando cromatografia gasosa com detectores seletivos

In the present work, a method was developed and validated for the quantification of benzyl isothiocyanate (BITC) in the fruits of Carica papaya. The quantification of this compound was carried out by gas chromatography (GC) with selective detectors - nitrogen phosphorus detector (NPD) and flame photometric detector (FPD). The performance of these detectors showed a higher sensitivity of the NPD with a broader linear range of detection. The LOD/LOQ were 0.038/0.100 µg/mL for NPD and 5.78/19.29 µg/mL for FPD. The recovery of the method for BITC was 90,64%. An average value of BITC concentration in all the analyzed samples was 16,23 µg BITC/g.

Sensortizació en aplicacions alimentàries

La societat actual es caracteritza pel seu ús intensiu i extensiu de les telecomunicacions, que ha esdevingut possible gràcies a la microelectrònica i altres tecnologies. Abans, la microelectrònica ja havia deixat la seva empremta en l’automatització i la computació, on la reducció de costos que hi aportava havia anat fent viables cada vegada més aplicacions. Aquest fet ha esdevingut particularment clar en l’automoció on fa relativament pocs anys els elements electrònics tenien un rol marginal i ara constitueixen una part important de tota mena de vehicles. Però mentre aquestes aplicacions afectaven principalment les màquines, les telecomunicacions involucren majoritàriament les persones i això ha implicat un esforç tecnològic addicional per aconseguir que els nous dispositius fossin assequibles per a molt usuaris.Aquest cicle “nova tecnologia que permet noves aplicacions que redueixen el cost de la tecnologia i això fa viables noves aplicacions”, no queda tancat dins cap àmbit d’aplicació sinó que té una dimensió totalment transversal. Els sensors, molts d’ells basats en tecnologies microelectròniques, són un paradigma del caràcter transversal de la tecnologia fins el punt que han esdevingut omnipresents, també en aplicacions alimentàries, tot i que encara hi hagi molts reptes per afrontar.En aquesta ponència s’exposaran en primer lloc els fonaments dels sensors i alguns dels avenços tecnològics que han marcat la seva evolució en els darrers anys. Després es revisaran algunes de les aplicacions actuals dels sensors en la indústria alimentària i els factors singulars que per una banda requereixen la incorporació de nous sensors i que per altra impedeixen que aquesta incorporació es pugui fer mitjançant la simple adaptació de solucions aplicades en altres indústries. Finalment, s’exposaran algunes tendències que es preveu que poden influir notablement en una major implantació dels sensors actuals i en el desenvolupament de nous sensors.

Avaliação da composição química de sedimentos do Rio Barigüi na região metropolitana de Curitiba

Sediment samples from the Barigui River in Curitiba, south of Brazil, were evaluated following granulometric composition, organic carbon content, nitrogen, phosphorus and metals such as zinc, lead, chrome, nickel and cadmium. The sediments shown high percentage of phosphorus and nitrogen. Also the elemental organic C:N:P exceed the Redfield ratios possible because the large amount of sewage input into river. The presence of metals is also high, however the metal cadmium has not been found. But the other metals are in greater concentrations and possibly the presence of these metals is given by industrial and domestic sewage.