La literatura infantil i juvenil de Jaume Cabré

Un dels aspectes més desconeguts de la trajectòria de Jaume Cabré com a escriptor és el seu interès per la literatura infantil i juvenil. Si bé la dedicació a aquest gènere consta només de quatre obres (les novel·les Galceran, l’heroi de la guerra negra, La història que en Roc Pons no coneixia i L’home de Sau; i la nouvelle L’any del Blauet) editades entre 1978 i 1984, els textos que en resulten mostren una gran similitud, tant pel que fa al tema com a l’estructura, amb la narrativa escrita per a adults, cosa que evidencia la coherència del món literari creat per l’autor.

The armies of the first French Republic and the rise of the marshals of Napoleon I ...

Preface signed: Charles F. Phipps.

Éloquence militaire ou l'art d'emouvoir le soldat : d'après les plus illustres exemples tirés des armées des différens Peuples; et principalement d'après proclamations, harangues, discours et paroles mémorables des généraux et officiers francais /

Precede al T. I: Extrait du catalogue des livres militaires et autres qui se trouvent chez Anselin (Successeur de Magimel)

The declaration of the kingdomes of England and Scotland, ioyned in armes for the vindication and defence of their religion, liberties, and lawes, against the popish, prelaticall, and malignant party;

Mode of access: Internet.

Morals on the book of Job /

Includes index.

Considérations sur les mouvemens stratégiques des armées francaises dans quelques-unes des campagnes de Napoleon Bonaparte, et particulièrement dans ses quatre dernières : suivies d'un mémoire ou l'on discute les avantages plus ou moins assurés que l'on trouverait à défendre la France contre une invasion, plutôt par des forces actives que par l'extension des places fortes ; et de trois cartes du théâtre de la guerre en 1806, 1812 et 1813, où sont tracées les différentes marches, et les opérations calculées par une méthode géométrique /

Mode of access: Internet.

Coelebs in search of a wife, comprehending observations on domestic habits and manners, religion and morals.

Mode of access: Internet.

Porcupine's works : containing various writings and selections, exhibiting a faithful picture of the United States of America; of their governments, laws, politics and resources; of the characters of their presidents, governors, legislators, magistrates, and military men; and of the customs, manners, morals, religion, virtues and vices of the people : comprising also a complete series of historical documents and remarks, from the end of the war, in 1783, to the election of the President, in March, 1801 /

continued: ... XII. Historical documents and remarks (from December, 1799 to March, 1801) ; Trial of Cooper ; Emigration Society ; Washington's death ; Proceedings in Congress during the session which began December, 1799 ; Board of Commissioners ; Defence of the Quakers of Pennsylvania ; Farewell advertisement ; Prison eclogue ; Republican morality ; Jefferson's election ; Adam's public conduct ; Jefferson's character ; Convention concluded between America and France, in 1800 ; Proceedings in Congress during the session which ended in March, 1801 ; Index.

Histoire du Vicomte de Turenne, Maréchal Général des Armées du Roy : tome second, contenant les Preuves en trois parties.

Histoire du Vicomte de Turenne, livre VI ; Preuves de l'Histoire du Vicomte de Turenne. Premiere partie, contenant les memoires du Vicomte ecrits de sa propre main ; Relation de la campagne de Fribourg par le Marquis de La Moussaye ; Preuves de l'Histoire du Vicomte de Turenne. Seconde partie, contenant plusieurs Lettres, Brevets, Instructions Politiques, & autres Pieces ; Preuves de l'Histoire du Vicomte de Turenne. Troisiéme partie, contenant les Memoires du Duc d'Yorck, depuis Jacques II Roi de la Grande-Bretagne.

Diàlechs [de les armes y llinatges de la noblesa d'Espanya]

Mode of access: Internet.

An investigation into the pharmacology of tics and tic-like movements

The study of tic-like movements in mice has demonstrated close parallels both in characteristics and in pharmacology with the tics which occur in TS. Head-shakes and/or other tic-like behaviours occurring spontaneously or induced by the selective 5-HT2/1C agonist DOI, alpha-melanocyte stimulating hormone, adrenocorticotrophic hormone (1-39), thyrotropin releasing hormone, or RX336-M were blocked when tested with neuroleptics such as haloperidol and/or the alpha-2 adrenoceptor agonist clonidine. The selective dopamine D1 antagonists SCH23390 and SCH39166 dose-dependently blocked spontaneous and DOI head-shakes but the selective dopamine D2 antagonists sulpiride and raclopride were ineffective. The 5-HT1A receptor agonists 8-OH-DPAT, ipsapirone, gepirone, MDL 73005EF and buspirone (i.p) dose-dependently blocked DOI head-shakes, pindolol blocked the inhibitory effect of 8-OH-DPAT on DOI head-shakes. Parachlorophenylalanine blocked the inhibitory effect of 8-OH-DPAT and buspirone, suggesting that the 5-HT1A receptor involved is located presynaptically. The alpha-2 adrenoceptor antagonists yohimbine, idazoxan, 1-PP and RX811059 prevented the inhibitory effect of 8-OH-DPAT on DOI head-shakes suggesting that this 5-HT1A - 5-HT2 receptor interaction is under the modulatory control of adrenoceptors. Because kynurenine has previously been found to potentiate head-shaking, plasma kynurenine concentrations were measured in seven TS patients and were significantly higher than controls, but neopterin and biopterin were unchanged. The relationship between tic-like movements in rodents and their implications for understanding the aetiology and treatment of TS is discussed.

TICs como herramientas de apoyo para estudiantes con TDAH

La enseñanza universitaria se encuentra sumergida en un proceso de cambios impulsados por la implantación de las TIC, que ha supuesto una revolución del concepto de enseñanza-aprendizaje. Con la llegada de dicha tecnología se superan barreras, haciendo más accesible el completo desarrollo, tanto personal como académico, del alumno con TDAH en el entorno universitario. Mediante el uso del iPad en el aula utilizando la conexión Airserver, que permite la proyección del contenido que se está visionando en dicho dispositivo a través de un cañón, así como la proyección simultánea del mismo en otro dispositivo personal, y acompañado de dos herramientas potentes, como son el iAnnotate y uPAD, se pretende mejorar y facilitar la vida académica no sólo de las personas con TDAH, sino de la población universitaria en general, ya que éste su uso permitirá una mayor organización de la información, así como una captación y remarcación más exhaustiva de los conceptos más importantes.

Aplicación e impacto de las tics en la enseñanza de las matemáticas: una revisión sistemática

Esta investigación buscó, recolectó, analizó y sistematizó información, en español, sobre estudios empíricos delas Tics aplicadas a la enseñanza de las matemáticas. Se utilizó el método de la revisión sistemática; las unidades de estudio fueron los artículos y tesis de maestría publicados en los últimos 5 años,a los que se pudo acceder a través de repositorios digitales de la Universidad de Cuenca: EBSCO, SCOPUS y COBUEC;de los 219 estudiosencontrados, en base a los criterios de inclusión y exclusión, se seleccionaron 13 con el objetivo de integrar sistemáticamente la información, determinar el estado del arte, impacto, aportaciones y limitaciones en la enseñanza de las matemáticas. Los resultados más importantes queobtuvieron de esta investigación son:Es escasa la información en español sobre las Tics en la enseñanza de las matemáticas realizadas en estudios empíricos;en el Ecuador la mayoría de las tesis de maestría sobre esta temática son propuestas metodológicas o guías didácticas. En los estudios analizados,el software Geogebra es el más utilizado y los temas más abordados son función lineal y ecuaciones lineales y se veque todos los estudios generan aportaciones y limitaciones en los estudiantes durante las intervenciones con las Tics en el proceso de enseñanza aprendizaje. Se puede concluir que utilizar adecuadamente las Tics en la enseñanza de las matemáticas puede ayudar a mejorar aspectos motivacionales, actitudinales y académicos en los estudiantes, aunque todavía queda abierto un gran campo por estudiar sobre esta temática, tanto en el nivel básico, secundario y superior.

An Isoflavone From Dipteryx Alata Vogel Is Active Against The In Vitro Neuromuscular Paralysis Of Bothrops Jararacussu Snake Venom And Bothropstoxin I, And Prevents Venom-induced Myonecrosis.

Snakebite is a neglected disease and serious health problem in Brazil, with most bites being caused by snakes of the genus Bothrops. Although serum therapy is the primary treatment for systemic envenomation, it is generally ineffective in neutralizing the local effects of these venoms. In this work, we examined the ability of 7,8,3'-trihydroxy-4'-methoxyisoflavone (TM), an isoflavone from Dipteryx alata, to neutralize the neurotoxicity (in mouse phrenic nerve-diaphragm preparations) and myotoxicity (assessed by light microscopy) of Bothrops jararacussu snake venom in vitro. The toxicity of TM was assessed using the Salmonella microsome assay (Ames test). Incubation with TM alone (200 μg/mL) did not alter the muscle twitch tension whereas incubation with venom (40 μg/mL) caused irreversible paralysis. Preincubation of TM (200 μg/mL) with venom attenuated the venom-induced neuromuscular blockade by 84% ± 5% (mean ± SEM; n = 4). The neuromuscular blockade caused by bothropstoxin-I (BthTX-I), the major myotoxic PLA2 of this venom, was also attenuated by TM. Histological analysis of diaphragm muscle incubated with TM showed that most fibers were preserved (only 9.2% ± 1.7% were damaged; n = 4) compared to venom alone (50.3% ± 5.4% of fibers damaged; n = 3), and preincubation of TM with venom significantly attenuated the venom-induced damage (only 17% ± 3.4% of fibers damaged; n = 3; p < 0.05 compared to venom alone). TM showed no mutagenicity in the Ames test using Salmonella strains TA98 and TA97a with (+S9) and without (-S9) metabolic activation. These findings indicate that TM is a potentially useful compound for antagonizing the neuromuscular effects (neurotoxicity and myotoxicity) of B. jararacussu venom.

Nebivolol Reduces Central Blood Pressure In Stage I Hypertensive Patients: Experimental Single Cohort Study.

Assessment of central blood pressure (BP) has grown substantially over recent years because evidence has shown that central BP is more relevant to cardiovascular outcomes than peripheral BP. Thus, different classes of antihypertensive drugs have different effects on central BP despite similar reductions in brachial BP. The aim of this study was to investigate the effect of nebivolol, a β-blocker with vasodilator properties, on the biochemical and hemodynamic parameters of hypertensive patients. Experimental single cohort study conducted in the outpatient clinic of a university hospital. Twenty-six patients were recruited. All of them underwent biochemical and hemodynamic evaluation (BP, heart rate (HR), central BP and augmentation index) before and after 3 months of using nebivolol. 88.5% of the patients were male; their mean age was 49.7 ± 9.3 years and most of them were overweight (29.6 ± 3.1 kg/m2) with large abdominal waist (102.1 ± 7.2 cm). There were significant decreases in peripheral systolic BP (P = 0.0020), diastolic BP (P = 0.0049), HR (P < 0.0001) and central BP (129.9 ± 12.3 versus 122.3 ± 10.3 mmHg; P = 0.0083) after treatment, in comparison with the baseline values. There was no statistical difference in the augmentation index or in the biochemical parameters, from before to after the treatment. Nebivolol use seems to be associated with significant reduction of central BP in stage I hypertensive patients, in addition to reductions in brachial systolic and diastolic BP.