Comparing meta-analysis and ecological-longitudinal analysis in time-series studies: a case study of the effects of air pollution on mortality in three Spanish cities

The objective of this paper is to introduce a diVerent approach, called the ecological-longitudinal, to carrying out pooled analysis in time series ecological studies. Because it gives a larger number of data points and, hence, increases the statistical power of the analysis, this approach, unlike conventional ones, allows the complementation of aspects such as accommodation of random effect models, of lags, of interaction between pollutants and between pollutants and meteorological variables, that are hardly implemented in conventional approaches. Design—The approach is illustrated by providing quantitative estimates of the short-termeVects of air pollution on mortality in three Spanish cities, Barcelona,Valencia and Vigo, for the period 1992–1994. Because the dependent variable was a count, a Poisson generalised linear model was first specified. Several modelling issues are worth mentioning. Firstly, because the relations between mortality and explanatory variables were nonlinear, cubic splines were used for covariate control, leading to a generalised additive model, GAM. Secondly, the effects of the predictors on the response were allowed to occur with some lag. Thirdly, the residual autocorrelation, because of imperfect control, was controlled for by means of an autoregressive Poisson GAM. Finally, the longitudinal design demanded the consideration of the existence of individual heterogeneity, requiring the consideration of mixed models. Main results—The estimates of the relative risks obtained from the individual analyses varied across cities, particularly those associated with sulphur dioxide. The highest relative risks corresponded to black smoke in Valencia. These estimates were higher than those obtained from the ecological-longitudinal analysis. Relative risks estimated from this latter analysis were practically identical across cities, 1.00638 (95% confidence intervals 1.0002, 1.0011) for a black smoke increase of 10 μg/m3 and 1.00415 (95% CI 1.0001, 1.0007) for a increase of 10 μg/m3 of sulphur dioxide. Because the statistical power is higher than in the individual analysis more interactions were statistically significant,especially those among air pollutants and meteorological variables. Conclusions—Air pollutant levels were related to mortality in the three cities of the study, Barcelona, Valencia and Vigo. These results were consistent with similar studies in other cities, with other multicentric studies and coherent with both, previous individual, for each city, and multicentric studies for all three cities

Development of an air-scour control system for membrane bioreactors

The thesis involves the development and implementation of a new and robust control system based on permeability trends but at the same time capable of reducing aeration proportionally to permeate flux. Permeability was made a key parameter for directly comparing temporary changes in membrane performance. Transmembrane pressure and flux were gathered every 10 seconds and permeability values were automatically calculated; different mathematical algorithms were applied for the signal filtering of on-line data. Short term and long term permeability trends were compared once a day, and a control action was applied proportionally to the short term/long term permeability ratio without exceeding the aeration flow recommended by the membrane suppliers.

Air cargo economics

Air Cargo Economics - Outline - Air cargo participants - Air cargo pricing, rates & yields - Cargo related costs - Freighter aircraft operating costs - Methods of cost allocation - Pax/combi vs freighter services - Lufthansa’s cargo strategy - Quick change aircraft - Aircraft wet leasing - Conclusions

Air traffic rights : the path to multilateralism

Types of Air ABSTRACT: Transport Trading Agreements - Bilateral - “Open Skies” - Plurilateral - Multilateral

Portugal and air transport in the early 21st century

The Nature of air transport 1. Air transport is important • It is a big industry • It is vital to many industries and regions 2. It is multi-facited • Airlines • Airports • Air traffic control • Domestic and international 3. It is a network Industry • Portugal is part of Europe (legal fact) • Portugal is part of the world (globalization) 4. It is not wanted for its own sake • It “facilitates” and does not create 5. It has environmental implications • Noise • Greenhouse gas emissions

An analysis of the relationship between immittance results and AC/BC

This paper analyzes subjects with air bone (A/B) gaps (a comparison of air-conducted thresholds and bone-conducted thresholds) and whether tympanometry (the type of tympanogram, static admittance, or peak pressure) can predict the size of the A/B gap.

Bone-conducted tones masked by air-conducted noise

This paper presents a study designed to develop and evaluate a method for obtaining monaural thresholds for bone-conducted signals masked by air-conducted noises.

Ocular vestibular evoked myogenic potentials (oVEMP) using air conducted sound: Effect of body position on threshold

The primary objective of this research study is to determine if various body positions for ocular vestibular evoked myogenic potential (oVEMP) testing demonstrate differentiation of the saccule and utricle through threshold responses.