An analysis of speculative trading in grain futures /

Reprint of An analysis of speculative trading in grain futures, Technical bulletin no. 1001, issued Oct. 1949.

Broker's loans : hearings before the Committee on Banking and Currency, United States Senate, Seventieth Congress, first session, on S. Res. 113, a resolution favoring a restriction of loans by federal reserve banks for speculative purposes. February 9, 29, and March 7, 1928 ...

Peter Norbeck, chairman.

Light on masonry : a collection of all the most important documents on the subject of speculative free masonry : embracing the reports of the Western committees in relation to the abduction of William Morgan : proceedings of conventions, orations, essays, &c &c : with all the degrees of the order conferred in a master's lodge, as written by Captain William Morgan ... : also, a revelation of all the degrees conferred in the lodge of perfecton and fifteen degrees of a still higher order with seven French degrees making forty-eight degrees of Free Masonry with notes and critical remarks /

Mode of access: Internet.

The philosophy of religion; a critical and speculative treatise of man's religious experience and development in the light of modern science and reflective thinking.

Mode of access: Internet.

Essays speculative and suggestive /

v. 1. The philosophy of evolution. On the application of evolutionary principles to art and literature. On some principles of criticism. The provinces of the several arts. On the relation of art to science and morality. Realism and idealism. The model. Beauty, composition, expression, characterisation. Caricature, the fantastic, the grotesque. Notes on style: History and usage of the word; National style.-v. 2. Notes on style: Personal style; The art of style. Democratic art, with special reference to Walt Whitman. Landscape. Nature myths and allegories. Is poetry at bottom a criticism of life? A review of Matthew Arnold's selection from Wordsworth. Is music the type or measure of all art? The pathos of the rose in poetry. A comparison of Elizabethan with Victorian poetry. Appendix.

An historical and critical view of the speculative philosophy of Europe in the nineteenth century /

Edition statement, [2nd ed.] from p. vii.

The Journal of speculative philosophy.

Editor: -Dec. 1893, Wm. T. Harris.

CODEX: mapping co-created data for speculative geographies

This paper discusses a series of artworks named CODEX produced by the authors as part of a collaborative research project between the Centre for Research in Education, Art and Media (CREAM), University of Westminster, and the Oxford Internet Institute. Taking the form of experimental maps, large-scale installations and prints, we show how big data can be employed to reflect upon social phenomena through the formulation of critical, aesthetic and speculative geographies.

Speculative document evaluation

Optimisation of real world Variable Data printing (VDP) documents is a dicult problem because the interdependencies between layout functions may drastically reduce the number of invariant blocks that can be factored out for pre-rasterisation. This paper examines how speculative evaluation at an early stage in a document-preparation pipeline, provides a generic and effective method of optimising VDP documents that contain such interdependencies. Speculative evaluation will be at its most effective in speeding up print runs if sets of layout invariances can either be discovered automatically, or designed into the document at an early stage. In either case the expertise of the layout designer needs to be supplemented by expertise in exploiting potential invariances and also in predicting the effects of speculative evaluation on the caches used at various stages in the print production pipeline.

Feminist environmental humanities: intertwining theory and speculative fiction

This dissertation explores the entanglement between the visionary capacity of feminist theory to shape sustainable futures and the active contribution of feminist speculative fiction to the conceptual debate about the climate crisis. Over the last few years, increasing critical attention has been paid to ecofeminist perspectives on climate change, that see as a core cause of the climate crisis the patriarchal domination of nature, considered to go hand in hand with the oppression of women. What remains to be thoroughly scrutinised is the linkage between ecofeminist theories and other ethical stances capable of countering colonising epistemologies of mastery and dominion over nature. This dissertation intervenes in the debate about the master narrative of the Anthropocene, and about the one-dimensional perspective that often characterises its literary representations, from a feminist perspective that also aims at decolonising the imagination; it looks at literary texts that consider patriarchal domination of nature in its intersections with other injustices that play out within the Anthropocene, with a particular focus on race, colonialism, and capitalism. After an overview of the linkages between gender and climate change and between feminism and environmental humanities, it introduces the genre of climate fiction examining its main tropes. In an attempt to find alternatives to the mainstream narrative of the Anthropocene (namely to its gender-neutrality, colour-blindness, and anthropocentrism), it focuses on contemporary works of speculative fiction by four Anglophone women authors that particularly address the inequitable impacts of climate change experienced not only by women, but also by sexualised, racialised, and naturalised Others. These texts were chosen because of their specific engagement with the relationship between climate change, global capitalism, and a flat trust in techno-fixes on the one hand, and structural inequalities generated by patriarchy, racism, and intersecting systems of oppression on the other.

A mathematical view of biological complexity

This essay is a trial on giving some mathematical ideas about the concept of biological complexity, trying to explore four different attributes considered to be essential to characterize a complex system in a biological context: decomposition, heterogeneous assembly, self-organization, and adequacy. It is a theoretical and speculative approach, opening some possibilities to further numerical and experimental work, illustrated by references to several researches that applied the concepts presented here. (C) 2008 Elsevier B.V. All rights reserved.

Impact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs

This report focuses on the effects of cholesterol on the expression and function of the ATP-binding cassette (ABCB1, ABCG2 and ABCC2) and solute-linked carrier (SLCO1B1 and SLCO2B1) drug transporters with a particular focus on the potential impact of cholesterol on lipid-lowering drug disposition. Statins are the most active agents in the treatment of hypercholesterolemia. However, considerable interindividual variation exists in the response to statin therapy. Therefore, it would be huge progress if factors were identified that reliably differentiate between responders and nonresponders. Many studies have suggested that plasma lipid concentrations can affect drug disposition of compounds, such as ciclosporin and amphotericin B. Both compounds are able to affect the expression and function of ABC transporters. Although still speculative, these effects might be owing to the regulation of drug transporters by plasma cholesterol levels. Studies with normo- and hyper-cholesterolemic individuals, before and after atorvastatin treatment, have demonstrated that plasma cholesterol levels are correlated with drug transporter expression, as well as being related to atorvastatin`s cholesterol-lowering effect. The mechanism influencing the correlation between cholesterol levels and the expression and function of drug transporters remains unclear. Some studies provide strong evidence that nuclear receptors, such as the pregnane X receptor and the constitutive androstane receptor, mediate this effect. In the near future, pharmacogenomic studies with individuals in a pathological state should be performed in order to identify whether high plasma cholesterol levels might be a factor contributing to interindividual oral drug bioavailability.

A Research Agenda for Assessing the Potential Contribution of Genomic Medicine to Tobacco Control

This paper identifies research priorities in evaluating the ways in which "genomic medicine"-the use of genetic information to prevent and treat disease-may reduce tobacco-related harm by: (1) assisting more smokers to quit; (2) preventing non-smokers from beginning to smoke tobacco; and (3) reducing the harm caused by tobacco smoking. The method proposed to achieve the first aim is pharmacogenetics", the use of genetic information to optimise the selection of smoking-cessation programmes by screening smokers for polymorphisms that predict responses to different methods of smoking cessation. This method competes with the development of more effective forms of smoking cessation that involve vaccinating smokers against the effects of nicotine and using new pharmaceuticals (such as cannabinoid antagonists and nicotine agonists). The second and third aims are more speculative. They include: screening the population for genetic susceptibility to nicotine dependence and intervening (eg, by vaccinating children and adolescents against the effects of nicotine) to prevent smoking uptake, and screening the population for genetic susceptibility to tobacco-related diseases. A framework is described for future research on these policy options. This includes: epidemiological modelling and economic evaluation to specify the conditions under which these strategies are cost-effective; and social psychological research into the effect of providing genetic information on smokers' preparedness to quit, and the general views of the public on tobacco smoking.

Social and psychiatric influences on urban-rural differentials in Australian suicide

The purpose of this study was to investigate urban-rural differentials in Australian suicide rates, and to examine influences that previously have remained largely speculative. Suicide rates for males (all ages and young adults) were significantly higher in rural areas compared to urban areas. Urban-rural suicide rate differences in males were rendered nonsignificant after adjustment for migrant and area socioeconomic status. Adjusting for mental disorder prevalence, in addition to migrant status, reduced the excess suicide risk in rural areas; the excess was reduced further with addition of mental health service utilization. The implications of this study are that socioeconomic circumstances in rural populations contribute to higher male suicide rates compared to urban areas, but these conditions may be partly mediated by mental disorder prevalence and mental health service utilization.