999 resultados para sotatoimet - taistelut - 1713


Relevância:

10.00% 10.00%

Publicador:

Resumo:

Com o presente texto pretendemos apresentar sucintamente as principais linhas de força dum projecto de investigação sobre as medidas políticas que configuram a ideia de Escola a Tempo Inteiro no âmbito do 1.º Ciclo do Ensino Básico optando por uma abordagem pela “análise das políticas públicas” centrado na formulação e implementação dessas medidas. Desta forma, procuramos assentar o estudo em dois “modos de abordagem” que se interligam: um centrado na análise do processo de decisão política, a partir do qual procuraremos compreender como nasceu e se transformou/transforma a política; outro na sua implementação focalizado no estudo da acção do Estado e no posicionamento dos seus actores em interacção com outros actores sociais. Como “ferramentas” teóricas optamos pela análise cognitiva das políticas públicas recorrendo, em particular, ao conceito de referencial e pela abordagem pelos instrumentos de acção pública.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Na era pós-moderna, as sociedades são tendencialmente multilingues e multiculturais. Esta diversidade impulsionou um intenso esforço político e educativo para implementar uma educação plurilingue e intercultural, nomeadamente em contexto europeu, que se refletiu no crescente interesse da Didática de Línguas por conceitos como intercompreensão, interculturalidade e plurilinguismo. Neste quadro, coloca-se um desafio à escola, e sobretudo aos professores de línguas: formar cidadãos responsáveis, críticos, capazes de assumir o papel de mediadores interculturais, fomentando o desenvolvimento de uma competência de comunicação plurilingue e intercultural. Uma das questões que se pode colocar, face a este desafio, é a seguinte: como encaram os professores de línguas o seu papel enquanto promotores desta educação plurilingue e intercultural? Nesta comunicação, analisamos as representações de um grupo de professores de línguas (materna e estrangeiras) portugueses relativamente ao perfil e papel do professor de línguas num contexto de educação para a diversidade linguística e cultural. Propomo-nos comparar os dados relativos aos professores de Português Língua Materna com os relativos aos professores de Línguas Estrangeiras, de forma a identificar divergências e/ou convergências, assim como fatores que lhes poderão estar subjacentes, com o intuito de problematizar potenciais possibilidades e/ou constrangimentos relativamente à implementação de uma didática integrada das línguas.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Every year European citizens become victims of devastating fires, which are especially disastrous for Southern European countries. Apart from the numerous health and economic consequences, fires generate hazardous pollutants that are introduced into the environment, thus representing serious risks for public health. In that regard, particulate matter (PM) is of amajor concern. Thus, the objectives of thisworkwere to characterize the trend of forest fire occurrences and burnt area during the period of 2005 and 2010 and to study the influence of forest fires on levels of particulatematter PM10 and PM2.5. In 2010, 22,026 forest fires occurred in Portugal. The northern region was the most affected by forest fires, with 27% of occurrences in Oporto district. The annual means of PM10 and PM2.5 concentrations at two urban background sites were 25±14 μg m−3 and 8.2±4.9 μg m−3, and 17±13 μg m−3 and 7.3±5.9 μg m−3, respectively. At both sites the highest levels of PMfractionswere observed during July and August of 2010, corresponding to the periods when majority (66%) of forest fires occurred. Furthermore, PM10 daily limit at the two sites was exceeded during 20 and 5 days, respectively; 56%, and respectively 60% of those exceedances occurred during the forest fire season. Considering that the risks of forest fire ignition and severity are enhanced with elevated temperatures, the climate change might increase the environmental impacts of forest fires.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

An approach for the analysis of uncertainty propagation in reliability-based design optimization of composite laminate structures is presented. Using the Uniform Design Method (UDM), a set of design points is generated over a domain centered on the mean reference values of the random variables. A methodology based on inverse optimal design of composite structures to achieve a specified reliability level is proposed, and the corresponding maximum load is outlined as a function of ply angle. Using the generated UDM design points as input/output patterns, an Artificial Neural Network (ANN) is developed based on an evolutionary learning process. Then, a Monte Carlo simulation using ANN development is performed to simulate the behavior of the critical Tsai number, structural reliability index, and their relative sensitivities as a function of the ply angle of laminates. The results are generated for uniformly distributed random variables on a domain centered on mean values. The statistical analysis of the results enables the study of the variability of the reliability index and its sensitivity relative to the ply angle. Numerical examples showing the utility of the approach for robust design of angle-ply laminates are presented.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

According to the OECD, Portugal is an example of a country with a very high rigidity in the labour market. At the same time, Portugal is an example of a country with a high percentage or workers with short-term contracts. These conditions have led to an ongoing public discussion concerning the nee to introduce more flexibility while maintaining work security. In this paper we analyze the current situation concerning security and rigidity in the labour market and discuss the flexicurity in the Portuguese context.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

A síncope neurocardiogénica é uma entidade com prevalência e incidência significativas. Apesar da baixa mortalidade relacionada com esta entidade, são significativas as implicações na qualidade de vida dos doentes. A metodologia para o seu diagnóstico está hoje claramente estabelecida nas recomendações internacionais e o teste de inclinação é um elemento útil na abordagem diagnóstica, em particular na síncope recorrente de causa desconhecida e frequente. Vários protocolos têm vindo a ser descritos nos últimos anos, inicialmente passivos e posteriormente com introdução de agentes provocativos, dos quais os nitratos sub-linguais são os mais largamente aceites, pela simplicidade e bons resultados da sua utilização. O recurso ao teste de inclinação na avaliação da terapêutica está limitado por problemas relacionados com a reprodutibilidade, que contudo estão na base de uma forma de tratamento – o treino de ortostatismo (tilt training) – embora com taxas de sucesso variáveis. Na presente revisão, iremos abordar os vários aspectos relacionados com a aplicação do teste de inclinação na prática clínica.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Existem vários métodos de Imagem que permitem avaliar a mama. Estes métodos têm conhecido uma evolução importante, quer por melhoria de técnicas como a mamografia, ecografia e Ressonância Magnética, quer pelo aparecimento de novas técnicas, como a tomossíntese. Os autores abordam as diferentes técnicas de Imagem da mama, as suas indicações e características, bem como alguns aspectos tecnológicos que correspondem a melhorias recentes.

Relevância:

10.00% 10.00%

Publicador:

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Magdeburg, Univ., Fak. für Mathematik, Diss., 2006

Relevância:

10.00% 10.00%

Publicador:

Resumo:

PURPOSE: The Cancer Vaccine Consortium of the Cancer Research Institute (CVC-CRI) conducted a multicenter HLA-peptide multimer proficiency panel (MPP) with a group of 27 laboratories to assess the performance of the assay. EXPERIMENTAL DESIGN: Participants used commercially available HLA-peptide multimers and a well characterized common source of peripheral blood mononuclear cells (PBMC). The frequency of CD8+ T cells specific for two HLA-A2-restricted model antigens was measured by flow cytometry. The panel design allowed for participants to use their preferred staining reagents and locally established protocols for both cell labeling, data acquisition and analysis. RESULTS: We observed significant differences in both the performance characteristics of the assay and the reported frequencies of specific T cells across laboratories. These results emphasize the need to identify the critical variables important for the observed variability to allow for harmonization of the technique across institutions. CONCLUSIONS: Three key recommendations emerged that would likely reduce assay variability and thus move toward harmonizing of this assay. (1) Use of more than two colors for the staining (2) collect at least 100,000 CD8 T cells, and (3) use of a background control sample to appropriately set the analytical gates. We also provide more insight into the limitations of the assay and identified additional protocol steps that potentially impact the quality of data generated and therefore should serve as primary targets for systematic analysis in future panels. Finally, we propose initial guidelines for harmonizing assay performance which include the introduction of standard operating protocols to allow for adequate training of technical staff and auditing of test analysis procedures.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

In this study, we aimed to evaluate the relationship between the rates of resistance of Pseudomonas aeruginosa to carbapenems and the levels and diversity of antibiotic consumption. Data were retrospectively collected from 20 acute care hospitals across 3 regions of Switzerland between 2006 and 2010. The main outcome of the present study was the rate of resistance to carbapenems among P. aeruginosa. Putative predictors included the total antibiotic consumption and carbapenem consumption in defined daily doses per 100 bed days, the proportion of very broad-spectrum antibiotics used, and the Peterson index. The present study confirmed a correlation between carbapenem use and carbapenem resistance rates at the hospital and regional levels. The impact of diversifying the range of antibiotics used against P. aeruginosa resistance was suggested by (i) a positive correlation in multivariate analysis between the above-mentioned resistance and the proportion of consumed antibiotics having a very broad spectrum of activity (coefficient = 1.77; 95% confidence interval, 0.58 to 2.96; P < 0.01) and (ii) a negative correlation between the resistance and diversity of antibiotic use as measured by the Peterson homogeneity index (coefficient = -0.52; P < 0.05). We conclude that promoting heterogeneity plus parsimony in the use of antibiotics appears to be a valuable strategy for minimizing the spread of carbapenem resistance in P. aeruginosa in hospitals.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Testosterone can benefit individual fitness by increasing ornament colour, aggressiveness, and sperm quality, but it can also impose both metabolic and immunological costs. However, evidence that testosterone causes immuno suppression in freely living populations is scant. We studied the effects of testosterone on one component of the immune system (i.e., the cell-mediated response to phytohaemagglutinin), parasite load, and metabolic rate in the common wall lizard, Podarcis muralis (Laurenti, 1768). For analyses of immunocompetence and parasitism, male lizards were implanted at the end of the breeding season with either empty or testosterone implants and were returned to their site of capture for 5-6 weeks before recapture. For analyses of the effects of testosterone on metabolic rate, male lizards were captured and implanted before hibernation and were held in the laboratory for 1 week prior to calorimetry. Experimental treatment with testosterone decreased the cell-mediated response to the T-cell mitogen phytohemagglutinin and increased mean metabolic rate. No effects of testosterone on the number of ectoparasites, hemoparasites, and resting metabolic rate could be detected. These results are discussed in the framework of the immunocompetence handicap hypothesis and the immuno-redistribution process hypothesis. [Authors]

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Recolecta sorgeix sota els auspicis de la Fundación para la Ciencia y la Tecnología (FECYT) i la Red Bibliotecas Universitarias Española (REBIUN) amb l'objectiu d'impulsar i coordinar la creació d'una infraestructura a nivell nacional de dipòsits digitals interoperables segons estàndards internacionals i actuar com a agència nacional respecte a la infraestructura global de dipòsits digitals científics com a part integrant de l'Espai Europeu de Recerca.Es presentaran els resultats i balanç de la seva activitat 2009 en el marc del Conveni Rebiun / Fecyt 2008-2009.