History and Epistemology of Science in the Classroom: The Synthesis of Quinine as a Proposal

The history of the quinine synthesis can be used as a case study to emphasize that science is influenced by social and historical processes. The first efforts toward the synthesis of this substance, which until recently was the only treatment for malaria, were by Perkin in 1856 when, trying to obtain quinine,,. he synthesized mauveine. Since then, the quest for the total synthesis of quinine involved several characters in a web of controversies. A major step in this process was made in 1918 by Rabe and Kindler, who proposed the synthesis of quinine from quinotoxine. Twenty-six years later, after obtaining the total synthesis of quinotoxine, Woodward and Doering announced the total synthesis of quinine. However, the lack of experimental details about Rabe and Kindler's process, associated with Woodward and Doering's failure to reproduce it, raised a series of doubts about the synthesis. Stork and colleagues questioned the veracity of the experimental data and even the scientific reputation of the involved researchers. Doubts remained alive until 2008, when Williams and Smith reported, not without reservations, the reproducibility of Rabe and Kindler's protocol. The scientific knowledge as a social and historical development, its legitimating process, and the absence of neutrality in science constitute aspects that can be discussed from this case study, providing significant contributions to science education, in particular, to the initial or continued training of chemistry teachers.

Representations of the Human/ Nonhuman Primate Divide: the Influence of Science, Fiction, and Science-Fiction on the Concept of 'Being Human'

For as far back as human history can be traced, mankind has questioned what it means to be human. One of the most common approaches throughout Western culture's intellectual tradition in attempts to answering this question has been to compare humans with or against other animals. I argue that it was not until Charles Darwin's publication of The Descent of Man and Selection in Relation to Sex (1871) that Western culture was forced to seriously consider human identity in relation to the human/ nonhuman primate line. Since no thinker prior to Charles Darwin had caused such an identity crisis in Western thought, this interdisciplinary analysis of the history of how the human/ nonhuman primate line has been understood focuses on the reciprocal relationship of popular culture and scientific representations from 1871 to the Human Genome Consortium in 2000. Focusing on the concept coined as the "Darwin-Müller debate," representations of the human/ nonhuman primate line are traced through themes of language, intelligence, and claims of variation throughout the popular texts: Descent of Man, The Jungle Books (1894), Tarzan of the Apes (1914), and Planet of the Apes (1963). Additional themes such as the nature versus nurture debate and other comparative phenotypic attributes commonly used for comparison between man and apes are also analyzed. Such popular culture representations are compared with related or influential scientific research during the respective time period of each text to shed light on the reciprocal nature of Western intellectual tradition, popular notions of the human/ nonhuman primate line, and the development of the field of primatology. Ultimately this thesis shows that the Darwin-Müller debate is indeterminable, and such a lack of resolution makes man uncomfortable. Man's unsettled response and desire for self-knowledge further facilitates a continued search for answers to human identity. As the Human Genome Project has led to the rise of new debates, and primate research has become less anthropocentric over time, the mysteries of man's future have become more concerning than the questions of our past. The human/ nonhuman primate line is reduced to a 1% difference, and new debates have begun to overshadow the Darwin-Müller debate. In conclusion, I argue that human identity is best represented through the metaphor of evolution: both have an unknown beginning, both have an indeterminable future with no definite end, and like a species under the influence of evolution, what it means to be human is a constant, indeterminable process of change.

EPA's Council for Regulatory Environmental Modeling : a case study of science policy implementation

As environmental problems became more complex, policy and regulatory decisions become far more difficult to make. The use of science has become an important practice in the decision making process of many federal agencies. Many different types of scientific information are used to make decisions within the EPA, with computer models becoming especially important. Environmental models are used throughout the EPA in a variety of contexts and their predictive capacity has become highly valued in decision making. The main focus of this research is to examine the EPA’s Council for Regulatory Modeling (CREM) as a case study in addressing science issues, particularly models, in government agencies. Specifically, the goal was to answer the following questions: What is the history of the CREM and how can this information shed light on the process of science policy implementation? What were the goals of implementing the CREM? Were these goals reached and how have they changed? What have been the impediments that the CREM has faced and why did these impediments occur? The three main sources of information for this research came from observations during summer employment with the CREM, document review and supplemental interviews with CREM participants and other members of the modeling community. Examining a history of modeling at the EPA, as well as a history of the CREM, provides insight into the many challenges that are faced when implementing science policy and science policy programs. After examining the many impediments that the CREM has faced in implementing modeling policies, it was clear that the impediments fall into two separate categories, classic and paradoxical. The classic impediments include the more standard impediments to science policy implementation that might be found in any regulatory environment, such as lack of resources and changes in administration. Paradoxical impediments are cyclical in nature, with no clear solution, such as balancing top-down versus bottom-up initiatives and coping with differing perceptions. These impediments, when not properly addressed, severely hinder the ability for organizations to successfully implement science policy.

Análisis bibliométrico de las publicaciones científicas argentinas en la categoría Agriculture, Multidisciplinary de la base de datos Web of Science (1997-2009)

El propósito del trabajo ha sido caracterizar el área de Agriculture, Multidisciplinary en Argentina, revisándose a nivel institucional, a través de la base de datos Web of Science, los trabajos realizados por investigadores en Instituciones argentinas y publicados en revistas internacionales con factor de impacto entre 1997 y 2009. En el contexto de América Latina, se han publicado 7795 trabajos de todos los tipos documentales y 7622 del tipo artículo o revisión en 49 revistas, y a nivel de Argentina se han encontrado 531 artículos o revisiones publicados en 31 revistas, la mayoría en inglés (80,23%), pero también en español (15,25%) y en portugués (4,33%). Por otro lado, se han analizado las Instituciones desde el punto de vista cuantitativo y cualitativo mediante diversos indicadores bibliométricos, como el Factor de Impacto Ponderado, el Factor de Impacto Relativo y la ratio número de citas frente a número de documentos, encontrándose que entre las instituciones más productivas destacan el Consejo Nacional de Investigaciones Científicas y Técnicas por el número de documentos y el Centro de Investigación y Desarrollo en Criotecnología de Alimentos por el Factor de Impacto Ponderado y por la ratio citas frente a documentos. Se observa una escasa colaboración internacional.

Cobertura y solapamiento de Web of Science y Scopus en el análisis de la actividad científica española en psicología

Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia

Cobertura y solapamiento de Web of Science y Scopus en el análisis de la actividad científica española en psicología

Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia

Cobertura y solapamiento de Web of Science y Scopus en el análisis de la actividad científica española en psicología

Este estudio tiene como primer objetivo conocer el volumen y evolución de la producción científica española en psicología a partir de las bases de datos del Web of Science (Thomson Reuters) y Scopus (Elsevier), durante el periodo 2000-2009. A partir de allí, se propone determinar cuáles son las revistas científicas más utilizadas por los psicólogos españoles para difundir sus trabajos a nivel internacional y comparar la cobertura y solapamiento de revistas y documentos que presentan ambas bases de datos. Se ofrecen datos cuantitativos, se estudia la posible correlación entre las dos bases de datos y se analiza el solapamiento de documentos y de revistas, el modelo de crecimiento que presentan y la dispersión de los trabajos, entre otros. Los resultados muestran que ambos sistemas de información son complementarios pero no excluyentes, así como la relevancia e importancia de las revistas españolas de psicología en la difusión de la investigación de esta disciplina en el contexto internacional de la ciencia

PanXML - a tool to create XML files for DOI registration of publications in the catalog DataCite of the German National Library of Science and Technology

The software PanXML is a tool to create XML files needed for DOI registration at the German National Library of Science and Technology (TIB). PanXML is distributed as freeware for the operating systems Microsoft Windows, Apple OS X and Linux. An XML file created by PanXML is based on the XSD file article-doi_v3.2.xsd. Further schemas may be added on request.

Análisis bibliométrico de las publicaciones científicas españolas en la categoría Construction & Building Technology de la base de datos Web of Science (1997-2008)

En este trabajo se analizan las publicaciones procedentes de instituciones españolas recogidas en las revistas de la categoría Construction & Building Technology de la base de datos Web of Science para el periodo 1997-2008. El número de revistas incluidas es de 35 y el número de artículos publicados ha sido de 760 (Article o Review). Se ha realizado una evaluación bibliométrica con dos nuevos parámetros: Factor de Impacto Ponderado y Factor de Impacto Relativo; asimismo se incluyen el número de citas y el número de documentos a nivel institucional. Entre los centros con una mayor producción científica destaca, como era de prever, el Instituto de Ciencias de la Construcción Eduardo Torroja (CSIC), mientras que atendiendo al Factor de Impacto Ponderado ocupa el primer lugar la Universidad de Vigo. Por otro lado, sólo dos revistas Cement and Concrete Research y Materiales de Construcción aglutinan el 45.26% de toda la producción científica española, con 172 trabajos cada una de ellas. En cuanto a la colaboración internacional, destacan países como Inglaterra, México, Estados Unidos, Italia, Argentina y Francia

Reflectance properties analysis of mineral based mortars for renders: research of their energy performance

Passive performance of buildings is nowadays one of the key points, not only for reducing energy consumption of buildings, but also for decreasing “fuel poverty”. Among the constructive systems in buildings, façades are the ones having higher influence on thermal performance in urban spaces. Lime renders are specialized systems which can improve not only the durability of the support but also the thermal properties. According to previous researches, a modification of their radiative properties can reduce thermal fluxes between 24% and 89%. In this paper, the influences of the aggregate content in lime pastes, as well as the nature of the aggregates, colour and roughness, on the visible near and medium infrared reflectance are analyzed. Ten types of aerial lime mortars were prepared and two methods of reflectance determination were performed. Finally, the effect of the resulted reflectance on the constructive systems of façades was analyzed using pseudotime-dependent software, for which an annulation of the thermal fluxes or significant reduction of them can be observed, when modifying the aggregate nature.

Characteristics of science/engineering equipment in academic settings, 1989-90 /

Mode of access: Internet.

Measurement of value of recorded scientific information; final report to Office of Science Information Service, National Science Foundation.

"AD-260 734."

Journal of research of the National Bureau of Standards.

Vols. 13-62 consist of Research papers no. RP691-RP2961.

Current projects on economic and social implications of science and technology.

Other slight variations in title.

Conference on disease with natural foci and parasitological problems...[Moscow, Leningrad, Academy of Science USSR, 1959]

"Sponsored by the Academy of Sciences of the USSR (Zoological Institute, Leningrad) and the Academy of Medical Sciences (Institute of Epidemiology and Microbiology imeni)...N. F. Gamaley."