Chapitres des disciples d'Évagre /

Includes bibliographical references and indexes.

Verprolin cytokinesis function mediated by the Hof one trap domain

In budding yeast, partitioning of the cytoplasm during cytokinesis can proceed via a pathway dependent on the contractile actomyosin ring, as in other eukaryotes, or alternatively via a septum deposition pathway dependent on an SH3 domain protein, Hof1/Cyk2 (the yeast PSTPIP1 ortholog). In dividing yeast cells, Hof1 forms a ring at the bud neck distinct from the actomyosin ring, and this zone is active in septum deposition. We previously showed the yeast Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) ortholog, verprolin/Vrp1/End5, interacts with Hof1 and facilitates Hof1 recruitment to the bud neck. A Vrp1 fragment unable to interact with yeast WASP (Las17/Bee1), localize to the actin cytoskeleton or function in polarization of the cortical actin cytoskeleton nevertheless retains function in Hof1 recruitment and cytokinesis. Here, we show the ability of this Vrp1 fragment to bind the Hof1 SH3 domain via its Hof one trap (HOT) domain is critical for cytokinesis. The Vrp1 HOT domain consists of three tandem proline-rich motifs flanked by serines. Unexpectedly, the Hof 1 SH3 domain itself is not required for cytokinesis and indeed appears to negatively regulate cytokinesis. The Vrp1 HOT domain promotes cytokinesis by binding to the Hof 1 SH3 domain and counteracting its inhibitory effect.

1st international conference on LGBT psychology and related fields

During the last decades there has been an increase in the theoretical and empirical body of knowledge in LGBT Psychologyandrelatedfields. However, thisnew bodyof knowledgeis still somewhatdispersedandnot widespread, which makes the process of affirming LGBT topics very difficult in the current international scientific scenario.

Dynamic mental representations of habitual behaviours: Food choice on a web-based environment

Aim: Rather than being rigid, habitual behaviours may be determined by dynamic mental representations that can adapt to context changes. This adaptive potential may result from particular conditions dependent on the interaction between two sources of mental constructs activation: perceived context applicability and cognitive accessibility . Method: T wo web-shopping simulations of fering the choice between habitually chosen and non-habitually chosen food products were presented to participants. This considered two choice contexts dif fering in the habitual behaviour perceived applicability (low vs. high) and a measure of habitual behaviour chronicity . Results: Study 1 demonstrated a perceived applicability ef fect, with more habitual (non-organic) than non-habitual (organic) food products chosen in a high perceived applicability (familiar) than in a low perceived applicability (new) context. The adaptive potential of habitual behaviour was evident in the habitual products choice consistency across three successive choices, despite the decrease in perceived applicability . Study 2 evidenced the adaptive potential in strong habitual behaviour participants – high chronic accessibility – who chose a habitual product (milk) more than a non-habitual product (orange juice), even when perceived applicability was reduced (new context). Conclusion: Results portray consumers as adaptive decision makers that can flexibly cope with changes in their (inner and outer) choice contexts.

ANÁLISE DAS CARACTERISTICAS FÍSICAS E QUIMICAS DA ÁGUA DO RIO DOCE A MONTANTE DA PEQUENA CENTRAL HIDROELÉCTRICA DE IRARA – GO

O presente trabalho objetivou avaliar as características físicas e químicas das águas do rio Doce (GO), a montante da PCH Irara. Foram realizadas seis amostragens bimestrais em cinco pontos de coleta, no período de julho/09 a junho/10 para variáveis: pH, temperatura, condutividade elétrica, salinidade, turbidez e total de sólido dissolvido. As características físicas e químicas observadas evidenciaram uma boa qualidade da água do rio Doce, considerando-se os padrões Resolução CONAMA N0 357, de 17 de março de 2005.