566 resultados para dying


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Neutrophils, eosinophils, and basophils play essential roles during microbe-induced and sterile inflammation. The severity of such inflammatory processes is controlled, at least in part, by factors that regulate cell death and survival of granulocytes. In recent years, major progress has been made in understanding the molecular mechanisms of granulocyte cell death and in identifying novel damage- and pathogen-associated molecular patterns as well as regulatory cytokines impacting granulocyte viability. Furthermore, an increased interest in innate immunity has boosted our overall understanding of granulocyte biology. In this review, we describe and compare factors and mechanisms regulating neutrophil, eosinophil, and basophil lifespan. Because dysregulation of death pathways in granulocytes can contribute to inflammation-associated immunopathology, targeting granulocyte lifespan could be therapeutically promising.

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The recent decision by Baroness Ashton to end the mandate of a number of European Union Special Representatives (EUSRs) and her proposal to integrate these posts within the European External Action Service have raised concerns among member states. In the view of Erwan Fouéré, these developments underline the urgency of a more comprehensive and strategic discussion between Baroness Ashton and the member states on the future role of EUSRs in the EU's expanding foreign policy tool box.

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Poem.

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Mode of access: Internet.

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Ms. copy of On the statue of the dying gladiator by G. R. Chinnery, the prize poem, attached at end.

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Nineveh (deserted settlement), Iraq; gypsum

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Jan van Scorel; 1 ft. 2 19/64 in.x 2 ft. 9/64 in.; oil on panel

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Mode of access: Internet.