Radon in groundwater contaminated by dissolved hydrocarbons in Santa Barbara d'Oeste, São Paulo State, Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Crítica em perspectiva semiótica: o caso de Barbara Heliodora

This research aims to analyze, based on the theories of French semiotics (or greimasian), the development of the critical text by Barbara Heliodora and drama criticism, a very popular genre in journalism and therefore of great relevance for scholars in the area. The corpus of this research will analyze nine texts by the author, giving priority to her early career (texts from 1957, 1958 and 1962) and her most recent texts (two from 2007 and one from 2010). The choice for greimasian Semiotics is justified because it is a methodology that provides all the necessary elements for interpretation of textual content and its relationship both in the business of the theater and journalism

Barbara Kirwan Papers - Accession 355

This collection consists of bylaws, constitutions, reports, and related records pertaining to the American Society of Interior Designers, Interior Design Educators Council, Foundation for Interior Design Education, the American Home Economics Association, and the South Carolina Home Economics Association; together with Kirwan’s teaching files and faculty information, including tests, classroom grade books and student papers, photographs, Winthrop committee papers, interior design projects, and correspondence.

Interview with Barbara Haigler

In this interview on December 3, 2012, Robert Ryals speaks to Barbara Haigler, an alumnus of Winthrop University, about her memories of campus life. This interview covers Haigler’s time at Winthrop until her graduation in 1957. Among other things, Haigler discusses her memories of dorm life, classes, and social events. This interview was conducted for inclusion into the Louise Pettus Archives and Special Collections Oral History Program.

Subjetividade construída: uma leitura sobre os trabalhos de Barbara Bloom

Esse artigo utiliza como referência a noção de “total design” desenvolvida por Hall Foster em 2002 e, através dela, busca se aproximar de dois trabalhos desenvolvidos pela artista Barbara Bloom (1951, Califórnia- EUA): The Reign of Narcissism (1989) e Mood Ring Home (2002). Consideramos o corpo de obras de Barbara Bloom como uma importante contribuição para o debate sobre papel que o design (em seu sentido ampliado) assume perante os mecanismos de produção e disseminação de formas culturais e de novas subjetividades no mundo contemporâneo.

Spatial and temporal variation in settlement, growth and condition of the rockfish species Sebastes caurinus and Sebastes carnatus in the Channel Islands region, Santa Barbara, CA

Survival during the early life stages of marine species, including nearshore temperate reef fishes, is typically very low, and small changes in mortality rates, due to physiological and environmental conditions, can have marked effects on survival of a cohort and, on a larger scale, on the success of a recruitment season. Moreover, trade offs between larval growth and accumulation of energetic resources prior to settlement are likely to influence growth and survival until this critical period and afterwards. Rockfish recruitment rates are notoriously variable between years and across geographic locations. Monitoring of rates of onshore delivery of pelagic juveniles (defined here as settlement) of two species of nearshore rockfishes, Sebastes caurinus and Sebastes carnatus, was done between 2003-2009 years using artificial collectors placed at San Miguel and Santa Cruz Island, off Southern California coast. I investigated spatiotemporal variation in settlement rate, lipid content, pelagic larval duration and larval growth of the newly settled fishes; I assessed relationships between birth date, larval growth, early life-history characteristics and lipid content at settlement, considering also interspecific differences; finally, I attempt to relate interannual patterns of settlement and of early life history traits to easily accessible, local and regional indices of ocean conditions including in situ ocean temperature and regional upwelling, sea surface temperature (SST) and Chlorophyll-a (Chl-a) concentration. Spatial variations appeared to be of low relevance, while significant interannual differences were detected in settlement rate, pelagic larval duration and larval growth. The amount of lipid content of the newly settled fishes was highly variable in space and time, but did not differ between the two species and did not show any relationships with early life history traits, indicating that no trade off involved these physiological processes or they were masked by high individual variability in different periods of larval life. Significant interspecific differences were found in the timing of parturition and settlement and in larval growth rates, with S. carnatus growing faster and breeding and settling later than S. caurinus. The two species exhibited also different patterns of correlations between larval growth rates and larval duration. S. carnatus larval duration was longer when the growth in the first two weeks post-hatch was faster, while S. caurinus had a shorter larval duration when grew fast in the middle and in the end of larval life, suggesting different larval strategies. Fishes with longer larval durations were longer in size at settlement and exhibited longer planktonic phase in periods of favourable environmental conditions. Ocean conditions had a low explanatory power for interannual variation in early life history traits, but a very high explanatory power for settlement fluctuations, with regional upwelling strength being the principal indicator. Nonetheless, interannual variability in larval duration and growth were related to great phenological changes in upwelling happened during the period of this study and that caused negative consequences at all trophic levels along the California coast. Despite the low explanatory power of the environmental variables used in this study on the variation of larval biological traits, environmental processes were differently related with early life history characteristics analyzed to species, indicating possible species-specific susceptibility to ocean conditions and local environmental adaptation, which should be further investigated. These results have implications for understanding the processes influencing larval and juvenile survival, and consequently recruitment variability, which may be dependent on biological characteristics and environmental conditions.

Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus

To enhance understanding of the metabolic indicators of type 2 diabetes mellitus (T2DM) disease pathogenesis and progression, the urinary metabolomes of well characterized rhesus macaques (normal or spontaneously and naturally diabetic) were examined. High-resolution ultra-performance liquid chromatography coupled with the accurate mass determination of time-of-flight mass spectrometry was used to analyze spot urine samples from normal (n = 10) and T2DM (n = 11) male monkeys. The machine-learning algorithm random forests classified urine samples as either from normal or T2DM monkeys. The metabolites important for developing the classifier were further examined for their biological significance. Random forests models had a misclassification error of less than 5%. Metabolites were identified based on accurate masses (<10 ppm) and confirmed by tandem mass spectrometry of authentic compounds. Urinary compounds significantly increased (p < 0.05) in the T2DM when compared with the normal group included glycine betaine (9-fold), citric acid (2.8-fold), kynurenic acid (1.8-fold), glucose (68-fold), and pipecolic acid (6.5-fold). When compared with the conventional definition of T2DM, the metabolites were also useful in defining the T2DM condition, and the urinary elevations in glycine betaine and pipecolic acid (as well as proline) indicated defective re-absorption in the kidney proximal tubules by SLC6A20, a Na(+)-dependent transporter. The mRNA levels of SLC6A20 were significantly reduced in the kidneys of monkeys with T2DM. These observations were validated in the db/db mouse model of T2DM. This study provides convincing evidence of the power of metabolomics for identifying functional changes at many levels in the omics pipeline.