776 resultados para Watson-Crick


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Crick, Henry A., includes Application for Loan, Jan. 8, 1885 and Mortgage Loan Envelope no. 637 for Jan. 1, 1885 – Jan. 1, 1890.

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Payment for the Atkins, Schmidt, Crick, Mank, Underwood and Crew accounts, Jan. 1, 1885.

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Payment for the Crick, Underwood, Crew, Mank, Atkins and Schmidt accounts, June 9, 1885.

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Payment for Atkins, Schmidt, Crick, Mank, Underwood and Crew accounts, June 16, 1886.

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Payment for Atkins, Schmidt, Crick, Mank, Crew and Rothrock accounts, Jan. 1, 1889.

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This is one of a series of short case studies describing how academic tutors at the University of Southampton have made use of learning technologies to support their students.

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The synthesis of modified nucleic acids has been the subject of much study ever since the structure of DNA was elucidated by Watson and Crick at Cambridge and Wilkins and Franklin at King's College over half a century ago. This review describes recent developments in the synthesis and application of these artificial nucleic acids, predominantly the phosphoramidites which allow for easy inclusion into oligonucleotides, and is divided into three separate sections. Firstly, modi. cations to the base portion will be discussed followed secondly by modi. cations to the sugar portion. Finally, changes in the type of nucleic acid linker will be discussed in the third section. Peptide Nucleic Acids ( PNAs) are not discussed in this review as they represent a separate and large area of nucleic acid mimics.