The effect of African Americans' ethnographic paradigms and cultural explanatory model of breast cancer in framing the male partner's attitudes and behaviors about the woman's breast cancer diagnosis

The disparate burden of breast cancer-related morbidity and mortality experienced by African American women compared with women of other races is a topic of intense debate in the medical and public health arenas. The anomaly is consistently attributed to the fact that at diagnosis, a large proportion of African American women have advanced-stage disease. Extensive research has documented the impacts of cultural factors and of socioeconomic factors in shaping African American women's breast-health practices; however, there is another factor of a more subtle influence that might have some role in establishing these women's vulnerability to this disease: the lack of or perceived lack of partner support. Themes expressed in the research literature reflect that many African American breast cancer patients and survivors consider their male partners as being apathetic and nonsupportive. ^ The purpose of this study was to learn how African American couples' ethnographic paradigms and cultural explanatory model of breast cancer frame the male partners' responses to the women's diagnosis and to assess his ability to cope and willingness to adapt to the subsequent challenges. The goal of the study was to determine whether these men's coping and adaptation skills positively or negatively affect the women's self-care attitudes and behaviors. ^ This study involved 4 African American couples in which the woman was a breast cancer survivor. Participants were recruited through a community-based cancer support group and a church-based cancer support group. Recruitment sessions were held at regular meetings of these organizations. Accrual took 2 months. In separate sessions, each male partner and each survivor completed a demographic survey and a questionnaire and were interviewed. Additionally, the couples were asked to participate in a communications activity (Adinkra). This activity was not done to fulfill any part of the study purpose and was not included in the data analysis; rather, it was done to assess its potential use as an intervention to promote dialogue between African American partners about the experience of breast cancer. ^ The questionnaire was analyzed on the basis of a coding schema and the interview responses were analyzed on the principles of hermeneutic phenomenology. In both cases, the instruments were used to determine whether the partner's coping skills reflected a compassionate attitude (positive response) versus an apathetic attitude (negative response) and whether his adaptation skills reflected supportive behaviors (the positive response) versus nonsupportive behaviors (the negative response). Overall, the women's responses showed that they perceived of their partners as being compassionate, yet nonsupportive, and the partner's perceived of themselves likewise. Only half of the women said that their partners' coping and adaptation abilities enabled them to relinquish traditional concepts of control and focus on their own well-being. ^ The themes that emerged indicate that African American men's attitudes and behaviors regarding his female partner's diagnosis of breast cancer and his ability to cope and willingness to adapt are influenced by their ritualistic mantras, folk beliefs, religious teachings/spiritual values, existential ideologies, socioeconomic status, and environmental factors and by their established perceptions of what causes breast cancer, what the treatments and outcomes are, and how the disease affects the entire family, particularly him. These findings imply that a culturally specific intervention might be useful in educating African American men about breast cancer and their roles in supporting their female partners, physically and psychologically, during diagnosis, treatment, and recovery. ^

Sea surafce temperature reconstruction for sediment core SU81-18

Reconstructing the impact of Heinrich events outside the main belt of ice rafting is crucial to understanding the underlying causes of these abrupt climatic events. A high-resolution study of a marine sediment core from the Iberian margin demonstrates that this midlatitude area was strongly affected both by cooling and advection of low-salinity arctic water masses during the last three Heinrich events. These paleoclimatic time series reveal the internal complexity of each of the last three Heinrich events and illustrate the value of parallel studies of the organic and inorganic fractions of the sediments.

Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathway

The rapid loss of muscle mass that accompanies many disease states, such as cancer or sepsis, is primarily a result of increased protein breakdown in muscle, and several observations have suggested an activation of the ubiquitin–proteasome system. Accordingly, in extracts of atrophying muscles from tumor-bearing or septic rats, rates of 125I-ubiquitin conjugation to endogenous proteins were found to be higher than in control extracts. On the other hand, in extracts of muscles from hypothyroid rats, where overall proteolysis is reduced below normal, the conjugation of 125I-ubiquitin to soluble proteins decreased by 50%, and treatment with triiodothyronine (T3) restored ubiquitination to control levels. Surprisingly, the N-end rule pathway, which selectively degrades proteins with basic or large hydrophobic N-terminal residues, was found to be responsible for most of these changes in ubiquitin conjugation. Competitive inhibitors of this pathway that specifically block the ubiquitin ligase, E3α, suppressed most of the increased ubiquitin conjugation in the muscle extracts from tumor-bearing and septic rats. These inhibitors also suppressed ubiquitination in normal extracts toward levels in hypothyroid extracts, which showed little E3α-dependent ubiquitination. Thus, the inhibitors eliminated most of the differences in ubiquitination under these different pathological conditions. Moreover, 125I-lysozyme, a model N-end rule substrate, was ubiquitinated more rapidly in extracts from tumor-bearing and septic rats, and more slowly in those from hypothyroid rats, than in controls. Thus, the rate of ubiquitin conjugation increases in atrophying muscles, and these hormone- and cytokine-dependent responses are in large part due to activation of the N-end rule pathway.

Perspectives on state-EPA grant activities /

Mode of access: Internet.

School of Nursing Class of 1982

Top Row: Joellyn M. Markey, Carol L. Kallewaard, Janet R. Sobel, Jacqueline L. Spatafora, Susan M. Tucker, Cynthia S. Gordon, Pamela J. Sanders, Carol M. Salinger, Marylou Rabaut, Connie R. Jarlsbers, Sylvia J. McKenney, Elizabeth A. Regan, Barabara S. Schelenker, Vandy L. Sherbin, Judy A. Srrbina, Susan K. Ginster, Lydia A. Robinson, Sandra L. Sprague, Beth A. Stegeman, Catherine T. Totte

Row 2: Kathleen M. Lahiff, Julia M. Markovich, Andra M. Rush, Darlene C. Ressler, Wendy K. Reigel, Beth L. Burch, Jewel E. Carpenter, Wendie L. Weber, Kay E. Jersey, karen D. Curl, Carol L. McGraw, Durene M. Elem, Linette perushi, Betty A. pulliams, Vicki E. Meffert, Harriettee Williams

Row 3: Beth A. Hoatlin, Rhonda C. Tolbert, Michelle R. Robertson, Lori A. Wissman, Marilyn S. Dietrich, Jayne E. Taylor, Jill M. Smith, Barbara J. House, Siobhan Gorman, Madeline L. Mobley, Joyce A. Williamson, Fay M. Wright

Row 4: Rosanne M. Hrqamiec, karen S. Nowak, Peggy J. Cameron, Mary V. Morris-Tucker, Frances L. Righmond, Marlene A. Baker, Karen J. Worden, Kathleen M. McGillivary, Janet L. wylie, Sandra K. Thompson

Row 5: Karen A. Cruickshank, Irene M. Dery, Ann M. Ignatowski, Elizabeth A. Peklo, Anne K. Waters, Laura E. Harvey, Mary M. Eggenberger, Wendy K. Kenyon, Kathleen M. Jordan, Elaine J. Zeilke, Barbara J. Waxman, Jolie A. Laker

Row 6: Velria M. Brown, Jane A. Burke, Marv A. Damken, Leau M. Stein, Cheryl Lumm Truzz, Deborah G. Thomas, Charlene L. Davis, Carol A. Zuber, Susan G. Toler, Betty M. Jones, Linda L. Kouba, Cynthia A. Lovell

Row 7: Kathy A. Churches, Dana L. Garrett, Mary E. Cella, Sarah E. Newton, Judy L. Benkeser, Lori J. Googel, Nancy H. Jenson, Helen I. Erickson, Rhetaugh G. Dumas, Norma K. Marshall, Karen M. Walker, Deborau D. Barrett, Janice M. Sinsabaugh, Vickie M. Rodla, Bonnie M. Mann, Cynthia R. Matthews, Karen L. Heithecker

Row 8: Judith Gniewek, Valerie A. Filkins, Mable A. Glass, Kathleen M. Dwyer, Diane M. Fritz, Susan D. Cook, Evon J. Goyer, Kathryn Greenleaf, Laurie Haan Abraham, Sharon Gwozdec, Karen J. Douglas, Claudette P. Bryan, Kathy L. Deniston, Carol A. Garon, Maureen goode, Jennifer A. Gegenheimer, Colette White, Mary C. Kuckuc, Mary S. Craft

Row 9: Joan M. Garbarino, Linda S. Farwell, Julie A. Cook, Susan M. Bolohan, Sharon A. Bailey, Deborah Babala, Kathleen M. Oldani, Mary E. Grace, Mary A. Moriarty, Marybeth Annessa, Martha A. Beaudry, Jamie M. Ashley, Sue Bohnet, Janice J. Bishop, Diana L. Beveridge, Catherine A. Belski, Debra R. Surdyk, Maureen A. Flaherty, Lisa M. Barron, Carole A. Fanelli

School of Nursing Class of 1986

Top Row: Lynn L. Applin, Amy Benner, Paula Broderick, Lisa B. Cohan, Catherine Collard, Beth A. Crawford, Cathleen M. Cupal, Andrea De Agoslino, Marivi G. Del Rosario, Patricia A. Dork, Nancy Farrington, Susan Foltz, Holly Franckowiak, Mary Franklin

Row 2: Kelly Garlow, Kathleen Gold, Renee Harris, Jody Becsey, Susan Bowman, Ann Marie Francel, Shelia Remy Smith, Sharon L. Holewinski, Colleen Kennedy, Dee Dee Hebert, Carolyn A. Hejkal, Wendy L. Hepworth

Row 3: Vicloria A. Hershey, Laura A. Hines, Jean Horner, Kimberly J. Howe, Joan L. Ilseman, Mary Jo Jay

Row 4: Suzanne Jennings, Suzanne Johnson, Janet Kaplan, Ann V. Kealy, Mary King, Lisa M. Kluk, Jane G. Kromer, Michelle Lajiness, Donna LaRoy, Christine Y. Lee

Row 5: Heidi Lewis, Betsy Livingston, Leslie Loll, Karen B. Majeske, Rita A. Markel, Megan McDonald, Sara J. McKenna, Jacquelin Merva, Monique A. Michael, Barbara Mueller

Row 6: Sandra Nelson, Barbara Nemenzik, Sherry Novak, Kristin Olson, Roberta A. Paas-Duda, Janet Patterson, Michelle L. Pecot, Dawn M. Popovics, Elizabeth Powaser, Cynthia J. Rabette

Row 7: Julie Ray, Susan M. Rice, Anne L. Richardson, Nancy Rockwell, Rhetaug G. Dumas, Cheryl E. Easley, Shake Ketefian, Janice B. Lindberg, Ruth E. Rogers, Nancy Schultz, Jean Schuster, Jean Scicluna

Row 8: Kathleen A. Sobczak, Mary Sokolik, Cheryl Stoyka, Vickie T. Sullivan, Susan A. Thompson, Margaret Venglarik, Sharon L. Wagner, Dorathy J. Washington, John J. Williams, Linda S. Wineland, Yvette L. Winia, Jody Wiser, Shannon H. Wright

CETA works--for business : a selection of employment and training programs with the private sector /

Includes index.

La thérapie cognitive-comportementale dans le traitement du TDAH chez l'adulte: état des connaissances

Essai doctoral présenté à la Faculté des Arts et des Sciences en vue de l'obtention du grade de doctorat en psychologie clinique (D.psy.)

Gestion de flotte avec fenêtres horaires : approches de résolution mixtes utilisant la programmation par contraintes

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Modèles et algorithmes pour les enchères combinatoires

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Métaheuristiques de recherche avec tabous pour le problème de synthèse de réseau multiproduits avec capacités

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Expansion multi-périodes d'un réseau local de télécommunications

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.