Photograph - Young girl, Mary. Ambrotype?

Young girl, Mary. Ambrotype? Ca. 1850s? Approximate age 9-12 years old. Rose coloured cheeks. Elaborate brass matting with decorative brass border in wooden case. 8.5mm x 9.5mm (blue sticker on front of case).

Ethics at War: Review of Elizabeth Scannell-Desch and Mary Ellen Doherty, Nurses in War: Voices from Iraq and Afghanistan

Compte-rendu / Review

Detrital Zircon Evidence for Non-Laurentian Provenance, Mesoproterozoic (ca. 1490-1450 Ma) Deposition and Orogenesis in a Reconstructed Orogenic Belt, Northern New Mexico, USA: Defining the Picuris Orogeny

Detrital zircon and igneous zircon U-Pb ages are reported from Proterozoic metamorphic rocks in northern New Mexico. These data give new insight into the provenance and depositional age of a >3-km-thick metasedimentary succession and help resolve the timing of orogenesis within an area of overlapping accretionary orogens and thermal events related to the Proterozoic tectonic evolution of southwest Laurentia. Three samples from the Paleoproterozoic Vadito Group yield narrow, unimodal detrital zircon age spectra with peak ages near 1710 Ma. Igneous rocks that intrude the Vadito Group include the Cerro Alto metadacite, the Picuris Pueblo granite, and the Penasco quartz monzonite and yield crystallization ages of 1710 +/- 10 Ma, 1699 +/- 3 Ma, and 1450 +/- 10 Ma, respectively. Within the overlying Hondo Group, a metamorphosed tuff layer from the Pilar Formation yields an age of 1488 +/- 6 Ma and represents the first direct depositional age constraint on any part of the Proterozoic metasedimentary succession in northern New Mexico. Detrital zircon from the overlying Piedra Lumbre Formation yield a minimum age peak of 1475 Ma, and similar to 60 grains (similar to 25%) yield ages between 1500 Ma and 1600 Ma, possibly representing non-Laurentian detritus originating from Australia and/or Antarctica. Detrital zircons from the basal metaconglomerate and the middle quartzite member of the Marquenas Formation yield minimum age peaks of 1472 Ma and 1471 Ma, consistent with earlier results. We interpret the onset of ca. 1490-1450 Ma deposition followed by tectonic burial, regional Al2SiO5 triple-point metamorphism, and ductile deformation at depths of 12-18 km to reflect a Mesoproterozoic contractional orogenic event, possibly related to the final suturing of the Mazatzal crustal province to the southern margin of Laurentia. We propose to call this event the Picuris orogeny.

Mitochondrial carbonic anhydrase CA VB: Differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles

A cDNA for a second mouse mitochondrial carbonic anhydrase (CA) called CA VB was identified by homology to the previously characterized murine CA V, now called CA VA. The full-length cDNA encodes a 317-aa precursor that contains a 33-aa classical mitochondrial leader sequence. Comparison of products expressed from cDNAs for murine CA VB and CA VA in COS cells revealed that both expressed active CAs that localized in mitochondria, and showed comparable activities in crude extracts and in mitochondria isolated from transfected COS cells. Northern blot analyses of total RNAs from mouse tissues and Western blot analyses of mouse tissue homogenates showed differences in tissue-specific expression between CA VB and CA VA. CA VB was readily detected in most tissues, while CA VA expression was limited to liver, skeletal muscle, and kidney. The human orthologue of murine CA VB was recently reported also. Comparison of the CA domain sequence of human CA VB with that reported here shows that the CA domains of CA VB are much more highly conserved between mouse and human (95% identity) than the CA domains of mouse and human CA VAs (78% identity). Analysis of phylogenetic relationships between these and other available human and mouse CA isozyme sequences revealed that mammalian CA VB evolved much more slowly than CA VA, accepting amino acid substitutions at least 4.5 times more slowly since each evolved from its respective human–mouse ancestral gene around 90 million years ago. Both the differences in tissue distribution and the much greater evolutionary constraints on CA VB sequences suggest that CA VB and CA VA have evolved to assume different physiological roles.

Notebook, ca. 1714

Paper notebook with Latin text including theses titled "Divisio deber constare partibus paucissimis," "Forma dat esse rei --Theses primae," "Simile non agit in simile probabir à Mr T. Foxcroft in Thesis hâc," and "Lux est Corpus probatur 1712 Thesis." The notebook includes unattached pages of various sizes and a paper fragment.

Notebook, ca. 1714

Paper notebook of Latin grammar including verb conjugations.

Lux est Corpus, ca. 1714

Single folded piece of paper with Latin text titled "Lux est Corpus."

Antithesis: Elementa in propriis..., ca. 1714

Paper notebook comprised of two folded sheets of paper with Latin texts.

Letter from Levi Hedge to President John Kirkland, [ca. 1823]

Levi Hedge, Professor of Logic and Metaphysics, wrote Harvard president John Kirkland requesting renovations to the house which he occupied. Hedge's house was situated on North Street (now Massachusetts Avenue). He notes that the kitchen has a leaky sink, loose and unusable shelves, and is insufficiently insulated.

Glazier's report, [ca. 1765-1775]

On verso: S. Hastings, S. Kendal. This report outlines the glass needed for College buildings in the mid-18th century. Estimates include windows for Hollis, Massachusetts, and Harvard Halls and an unspecified College House.

Engravings of a plan and an exterior view of Harvard Hall drawn by Pierre Eugène du Simitière, (photographic prints, photostats, and negative photostats), [ca. 1764]

The floor plan details all three floors of Harvard Hall, including its cellars, kitchen, chapel, and library. The items in this folder were reproduced from "The Burning of Harvard Hall, 1764, and its consequences," presented by F. Apthorp Foster at the April 1911 meeting of the Colonial Society of Massachusetts, and published in the Publications of the Colonial Society of Massachusetts, Volume XIV. The floor plan and exterior views were created by Pierre Eugène du Simitière in circa 1764. The original drawings are held in the Pierre Eugène du Simitière collection in the Ridgeway Branch of the Library Company of Philadelphia.

Measures of hall and chapel, [ca. 1800]

This note, likely in the hand of President Willard, directs Mr. [Josiah] Moore and Mr. [John] Walton measure the length, width, and height of the chapel, hall, and library in Harvard Hall. Includes each room's measurements.

Estimate for shutters for Harvard Hall, [ca. 1806]

Itemized list of cost estimates for shutters for Harvard Hall, compiled circa 1806. Includes supplies needed to install shutters for 24 windows in Harvard Hall. Materials needed include boards, nails, and cross corner hinges.