Narrative of the life and sufferings of Rev. William B. Lighton : containing an interesting and faithful account of his early life, and enlistment into the British army; his experience while in the service, and escape from his regiment; capture, imprisonment, trial, and condemnation to death; his subsequent sufferings, and final escape from captivity, and settlement in the United States /

Mode of access: Internet.

Narrative of the life and sufferings of Rev. William B. Lighton; containing an interesting and faithful account of his early life, and enlistment into the British army; his experience while in the service, and escape from his regiment; capture, imprisonment, trial, and condemnation to death; his subsequent sufferings, and final escape from captivity, and settlement in the United States.

Added t.-p., engr.

Memoirs of Maria Antoinetta, Archduchess of Austria, Queen of France and Navarre : including several important periods of the French Revolution, from its origin to the 16th of October, 1793, the day of Her Majesty's martyrdom, with a narrative of the trial and martyrdom of Madame Elizabeth, the poisoning of Louis XVII in the temple, the liberation of Madame Royale, daughter of Louis XVI, and various subsequent events /

Vol. 2 translated by R. May ; v. 3 by Mrs. Ievers.

The crisis of heaven's love and earth's hate : in the trial and crucifixion of the Lord Jesus Christ /

Cover title: Heaven's love and earth's hate.

The trial and death of Jesus Christ; a devotional history of our Lord's passion.

Includes bibliographical references.

Historical sketches of Charles the First, Cromwell, Charles the Second, and the principal personages of that period : including the king's trial and execution: to which is annexed an account of the sums exacted by the commonwealth from the royalists, and the names of all those who compounded for their estates; with other scarce documents. Illustrated by fifty lithographic plates.

Mode of access: Internet.

The trial and acquittal of Ezra Haskell for the charge of forgery.

Mode of access: Internet.

The fatal effects of gambling exemplified in the murder of Wm. Weare, and the trial and fate of John Thurtell, the murderer, and his accomplices : with biographical sketches of the parties concerned ... : to which is added, the Gambler's scourge, a complete exposé of the whole system of gambling in the metropolis, with memoirs and anecdotes of notorious blacklegs.

Goldsmiths'-Kress no. 24260.

The life, trial, and death of Francisco Ferrer /

Mode of access: Internet.

A treatise on new trial and appellate practice; presenting and illustrating the laws and rules of practice in proceedings subsequent to decisions by trial courts, including final disposition in appellate court, with special reference to the code and statutes of California, Idaho, Montana, Nevada, North Dakota, Oregon, South Dakota, Utah, Washington, Wyoming, and the territories of Arizona and New Mexico ...

Paged continuously.

Consumer-identified barriers and strategies for optimizing technology use in the workplace

Purpose. This article explores the experiences of 26 assistive technology (AT) users having a range of physical impairments as they optimized their use of technology in the workplace. Method. A qualitative research design was employed using in-depth, open-ended interviews and observations of AT users in the workplace. Results. Participants identified many factors that limited their use of technology such as discomfort and pain, limited knowledge of the technology's features, and the complexity of the technology. The amount of time required for training, limited work time available for mastery, cost of training and limitations of the training provided, resulted in an over-reliance on trial and error and informal support networks and a sense of isolation. AT users enhanced their use of technology by addressing the ergonomics of the workstation and customizing the technology to address individual needs and strategies. Other key strategies included tailored training and learning support as well as opportunities to practice using the technology and explore its features away from work demands. Conclusions. This research identified structures important for effective AT use in the workplace which need to be put in place to ensure that AT users are able to master and optimize their use of technology.

Finite-size effects and error-free communication in Gaussian channels

The efficacy of a specially constructed Gallager-type error-correcting code to communication in a Gaussian channel is examined. The construction is based on the introduction of complex matrices, used in both encoding and decoding, which comprise sub-matrices of cascading connection values. The finite-size effects are estimated for comparing the results with the bounds set by Shannon. The critical noise level achieved for certain code rates and infinitely large systems nearly saturates the bounds set by Shannon even when the connectivity used is low.

Public key cryptography and error correcting codes as Ising models

We employ the methods of statistical physics to study the performance of Gallager type error-correcting codes. In this approach, the transmitted codeword comprises Boolean sums of the original message bits selected by two randomly-constructed sparse matrices. We show that a broad range of these codes potentially saturate Shannon's bound but are limited due to the decoding dynamics used. Other codes show sub-optimal performance but are not restricted by the decoding dynamics. We show how these codes may also be employed as a practical public-key cryptosystem and are of competitive performance to modern cyptographical methods.

Developing a scalable model of recombinant protein yield from Pichia pastoris:the influence of culture conditions, biomass and induction regime

Background The optimisation and scale-up of process conditions leading to high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences. Typical experiments rely on varying selected parameters through repeated rounds of trial-and-error optimisation. To rationalise this, several groups have recently adopted the 'design of experiments' (DoE) approach frequently used in industry. Studies have focused on parameters such as medium composition, nutrient feed rates and induction of expression in shake flasks or bioreactors, as well as oxygen transfer rates in micro-well plates. In this study we wanted to generate a predictive model that described small-scale screens and to test its scalability to bioreactors. Results Here we demonstrate how the use of a DoE approach in a multi-well mini-bioreactor permitted the rapid establishment of high yielding production phase conditions that could be transferred to a 7 L bioreactor. Using green fluorescent protein secreted from Pichia pastoris, we derived a predictive model of protein yield as a function of the three most commonly-varied process parameters: temperature, pH and the percentage of dissolved oxygen in the culture medium. Importantly, when yield was normalised to culture volume and density, the model was scalable from mL to L working volumes. By increasing pre-induction biomass accumulation, model-predicted yields were further improved. Yield improvement was most significant, however, on varying the fed-batch induction regime to minimise methanol accumulation so that the productivity of the culture increased throughout the whole induction period. These findings suggest the importance of matching the rate of protein production with the host metabolism. Conclusion We demonstrate how a rational, stepwise approach to recombinant protein production screens can reduce process development time.