Strategic Resources Framework 2011/2012 (944 KB)

2011/12

HSCB/PHA Draft Commissioning Plan 2011/2012

The draft Commissioning Plan was approved by the boards of the HSCB and PHA on Thursday 30 June 2011 for onward transmission to the DHSSPS for Ministerial consideration.Further refinement of the draft plan will take place in July and early August with a view to bringing a final draft plan to the August board meetings of the HSCB and PHA.

PHA Corporate business plan 2011-2012

The PHA Corporate Business Plan 2011-2012 is based on the four core goals and the common themes from the Corporate Strategy 2011-2015 and sets out a corporate picture of how the goals will be taken forward in year one (2011-2012) in line with existing AMT and board direction.�All Directorates were involved in developing the Corporate Business Plan and it reflects the content of each of the Directorate business plans.�It identifies a number of measurable indicators taken from the DHSSPS Commissioning Directions 2011-2012, as well as from each of the Directorate business plans.The Corporate Business Plan was approved by AMT on 1 November and by the PHA board on 17 November. Quarterly monitoring reports on progress against the indicators will be brought to the PHA board.

Treball de Fi de Carrera d´ETI

L'objectiu d'aquest treball és dissenyar, desenvolupar i implementar una aplicació que permeti pal·liar les deficiències del sistema actual que utilitza l'empresa

Gestor centralitzat d'accessos

El present treball de fi de màster té com a objectiu la creació d'una aplicació de gestió centralitzada d'accessos d'usuaris a servidors GNU/Linux, de manera que els autoritzats puguin accedir als servidors corresponents sense necessitat d'utilitzar una validació per username i contrasenya; aquest punt serà possible gràcies a la validació per clau pública sota protocol SSH.

Home enteral nutrition in Spain; NADYA registry 2011-2012.

To describe the results of the home enteral nutrition (HEN) registry of the NADYA-SENPE group in 2011 and 2012. MATERIAL AND METHODS: We retrieved the data of the patients recorded from January 1st 2011 to December 31st 2012. RESULTS: There were 3021 patients in the registry during the period from 29 hospitals, which gives 65.39 per million inhabitants. 97.95% were adults, 51.4% male. Mean age was 67.64 ± 19.1, median age was 72 years for adults and 7 months for children. Median duration with HEN was 351 days and for 97.5% was their first event with HEN. Most patients had HEN because of neurological disease (57.8%). Access route was nasogastric tube for 43.5% and gastrostomy for 33.5%. Most patients had limited activity level and, concerning autonomy, 54.8% needed total help. Nutritional formula was supplied from chemist's office to 73.8% of patients and disposables, when necessary, was supplied from hospitals to 53.8% of patients. HEN was finished for 1,031 patients (34.1%) during the period of study, 56.6% due to decease and 22.2% due to recovery of oral intake. CONCLUSIONS: Data from NADYA-SENPE registry must be explained cautiously because it is a non-compulsory registry. In spite of the change in the methodology of the registry in 2010, tendencies regarding HEN have been maintained, other than oral route

L'equilibri en la força

Aquesta unitat didàctica desenvolupada durant el Màster de Professorat de Secundària està pensada per ser impartida a l’assignatura Física i Química de 4t d’ESO, més concretament a la part de física, com introducció a la Dinàmica. Es parteix de les idees prèvies de l’alumnat sobre situacions quotidianes on hi actuen forces. Es contrasten aquestes amb una posada en comú i amb l’explicació del professor, que va introduint progressivament conceptes nous com l’equilibri o els vectors, a mesura que es fan necessaris. En les sessions posteriors s’insisteix en el caràcter vectorial de les forces i es centra l’atenció en dos casos particulars: la força de fregament i la força elàstica. Sobre aquestes dues es treballa resolent un cas i fent una experiència pràctica, fomentant la competència comunicativa. La finalitat de la metodologia és acabar construint les Lleis de Newton, les quals hauran d’exposar en una presentació al final de la unitat.

Relação dos Estagiários e seus Orientadores com as TIC: um Estudo Realizado no Ano Letivo 2011/2012 no Departamento de Ciências Sociais e Humanas da Universidade de Cabo Verde

No contexto das atividades de formação de professores ao nível da Universidade Pública de Cabo Verde (Uni-CV), constatamos que existem algumas dificuldades associadas ao funcionamento dos estágios pedagógicos, que consideramos poderem ser superadas com recurso às tecnologias de informação e comunicação (TIC). Entendemos que o estágio curricular constitui uma das etapas decisivas para os futuros docentes de ensino secundário no país, garantindo-lhes a oportunidade de contato com estratégias de trabalho atuais e inovadoras para esses contextos. Esta comunicação enquadra-se num processo de investigação-ação que pretende dinamizar as metodologias de trabalho com os estagiários e seus orientadores no Departamento de Ciências Sociais e Humanas no campus do Palmarejo da Uni-CV. Para tal, pretende-se recorrer à dinamização de um espaço virtual na Moodle, de forma a superar algumas das dificuldades previamente identificadas. Os dados aqui apresentados resultam de um diagnóstico de necessidades de formação e representam uma breve avaliação das condições existentes para o acompanhamento dos estágios pedagógicos através de um ambiente online, onde se constatou que os estagiários e seus orientadores, além de serem utilizadores e terem bons conhecimentos das TIC, gostariam de poder contar com um espaço virtual que os apoiasse ao longo de todo o estágio.

Comparativa treball individual vs. treball de parella. Anàlisi a través de diferents tipologies de textos científics i preferències de l'alumnat

Els alumnes elaboren produccions de qualitat superior quan treballen en parelles que quan ho fan individualment. Sota aquesta màxima, l’estudi demostra que quan els alumnes escriuen textos científics descriptius, justificatius i descriptius-justificatius en parella milloren aspectes relacionats amb determinades habilitats inherents a qualsevol tipus de text, com l’estructuració de la informació i l’adequació del llenguatge al context, i d’altres específiques de textos descriptius i justificatius. És sorprenent constatar que aquesta millora es dóna en tot tipus d’alumnes, tant aquells amb hàbits d’estudi superiors com aquells amb dificultats d’aprenentatge, i que els avantatges d’aquesta metodologia de treball no es circumscriuen tan sols a l’àmbit acadèmic; els alumnes prefereixen treballar en parella perquè els permet compartir punts de vista i ajudar-se mútuament. Per tant, els resultats demostren que complementar les classes de ciències amb el treball en parella possibilita assolir amb més garanties l’aprenentatge significatiu dels nostres alumnes.

Iowa Civil Rights Commission Agency Performance Plan and Action Plan,FY 2011-2012

Agency performancce plan and action plan for the Iowa Civil Rights Commission

The Iowa Official Register, 2011-2012

The Iowa Official Register, commonly known as the "Redbook," serves as a biographical and historical record of Iowa's leaders, government and people.

Iowa College Student Aid Commission Annual Report FY 2011-2012

Iowa College Student Aid Commission Annual Report

Neutralizing antibodies in Multiple Sclerosis a model-based analysis of Interferon beta signaling pathway in macrophages

Multiple Sclerosis is the most common non-traumatic cause of neurologicaldisability in young people. There is no cure yet, and until recently, few long-termtherapies existed. Interferon beta (IFNβ) was the first treatment, and remains the mostcommonly prescribed. One of the most significant problems of IFNβ therapy is theproduction of drug specific antibodies. Up to 45% of patients develop neutralizingantibodies (NAbs) to IFNβ products. The neutralizing antibody binds to the biologicalagent preventing its interaction with its receptor, inhibiting the biological action of theprotein, which abrogates the clinical efficacy of IFNβ treatment. Interferon-betamediates its response by binding to its high affinity cell surface receptor and initiatingthe JAK/STAT signalling cascade. In this project we have analyzed the IFNβ signalingpathway in macrophages when neutralizing antibodies are present. The response tothis pathway after IFNβ stimulation shows a transient oscillatory rhythm of STAT1phosphorylation, which varies as NAbs concentration increases. To improve ourunderstanding of that behavior, we extended an existing mathematical model based onnonlinear ordinary differential equations of JAK/STAT pathway by including IFN-NAbassociation and IFN-activation receptor. Combining our theoretical model withexperimental data we could study the role of neutralizing antibodies on the molecularresponse and determine its lifetime after cytokine stimulation.

Evolutionary analysis of genetic variants involved in rare diseases

Next-generation sequencing techniques such as exome sequencing can successfully detect all genetic variants in a human exome and it has been useful together with the implementation of variant filters to identify causing-disease mutations. Two filters aremainly used for the mutations identification: low allele frequency and the computational annotation of the genetic variant. Bioinformatic tools to predict the effect of a givenvariant may have errors due to the existing bias in databases and sometimes show a limited coincidence among them. Advances in functional and comparative genomics are needed in order to properly annotate these variants.The goal of this study is to: first, functionally annotate Common Variable Immunodeficiency disease (CVID) variants with the available bioinformatic methods in order to assess the reliability of these strategies. Sencondly, as the development of new methods to reduce the number of candidate genetic variants is an active and necessary field of research, we are exploring the utility of gene function information at organism level as a filter for rare disease genes identification. Recently, it has been proposed that only 10-15% of human genes are essential and therefore we would expect that severe rare diseases are mostly caused by mutations on them. Our goal is to determine whether or not these rare and severe diseases are caused by deleterious mutations in these essential genes. If this hypothesis were true, taking into account essential genes as a filter would be an interesting parameter to identify causingdisease mutations.