Avaliação de concentrações do C-Telopeptideo de Colágeno (CTX) em mulheres no climatério

Fundação de Apoio à Pesquisa do Estado do Rio Grande do Norte

Avaliação dos parâmetros hematológicos e imunofenotípicos de pacientes com doenças linfoproliferativas crônicas no Rio Grande do Norte

Chronic lymphoproliferative disorders (DLPC) are lymphoid system diseases characterized by the abnormal proliferation of mature lymphocytes that affect B cells, T lymphocytes and NK cells. The aim of the study was to demonstrate the relevance of immunophenotyping by flow cytometry in patients with prolonged lymphocytosis and / or cytomorphological changes compatible with lymphoproliferative diseases. In this study 460 patients (244 men and 216 women) with DLPC were evaluated. Were analyzed by flow cytometry with a panel of monoclonal antibodies consisting of CD3, CD4, CD5, CD8, CD10, CD19, CD22, CD23, CD25, CD38, CD45, CD16/CD56, and HLADR heavy and light chains of immunoglobulins. It also examines information regarding age, gender of patients and laboratory data as leucocytes, cytomorphological analysis, platelet count and hemoglobin determination. The results showed 398 cases of chronic lymphoproliferative disorders and 62 of DLPC B cell lymphoproliferative diseases T. B showed the following distribution : 253 cases of chronic lymphocytic leukemia (CLL), 42 cases of multiple myeloma ( MM ), 37 cases of lymphoma non - Hodgkin lymphoma in leukemic phase (NHL) , 17 cases of pro- B lymphocytic leukemia ( B -PLL), 15 cases of mantle cell lymphoma (MCL ), 12 cases of plasma cell leukemia ( PCL), 9 cases of lymphoma Burkitt (Linf B), 8 cases of leukemia villous cells ( LCV), 3 cases of splenic lymphoma with villous cells (LECV), a case of follicular lymphoma (LF) and a Waldenströn macroglobulinemia ( MW). The diseases source NK / T were 23 cases of peripheral T cell lymphoma (LCTP), 14 cases of T prolymphocytic leukemia (T -PLL), 10 cases of leukemia T of large granular lymphocytes (LGL -T) 9 cases of leukemia cells of adult T (LCTA), 5 cases of Sezary syndrome (SS) and a case of large granular NK leukemia (LGL -NK) lymphocytes. In conclusion, the combined use of the monoclonal antibody panel careful cytomorphological analysis was shown to be essential in immune diagnosis and classification of chronic lymphoproliferative disorders. This study was approved by the IRB - HUOL under number 356 / 09

Avaliação da eficácia de um programa de "Escola de Coluna" para lombalgia crônica inespecífica

The Back School has been used to prevent and to treat back pain since 1969, however its effectiveness still is controversy in literature. The objective of this study was to evaluate the effectiveness of a program of "Back School" in patients with nonspecific chronic low back pain, directed by rheumatologists and orthopedic doctors to Physiotherapy School Clinic of Universidade Potiguar (UnP) Natal/RN- Brazil, in period of May/2002 to December/2003. Seventy patients, with age varying from 18 to 60 years, were randomized in two groups: Experimental group (group A) with 34 patients, which was subdivided in groups with 6 to 8 components. This group participated of a theoretician and practical program of Back School with 4 lessons, one day per week, with 60 minutes of duration; to the Control group (group B), with 36 patients, was explained that the group should stay four months in a waiting list . Both groups, had been carried through three evaluations, by a blind, to patient group, independent observer: initial evaluation, after four and sixteen weeks. The following variables were analyzed: pain intensity, measured by analog visual scale (AVS), functional disability, measured by disability questionnaire of Roland and Morris and the spinal mobility measured by Schöber s method. In statistical analysis it was used variance analysis ANOVA, the test of Newman-Keuls multiple comparations, and the Pearson correlation coefficient, with significance level p<0.05. Thirteen patients (18,6%) didn t complete the evaluations, (5 from experimental group and 8 from control group). At last, 57 patients were studied, (29 from Experimental group and 28 from Control group), it was observed a significant statistical improve just for Experimental group in variables pain intensity (p=0,0001), functional disability

Avaliação clínica da relação entre o índice de placa, índice gengival, alinhamento dental, mucosa ceratinizada, tipo de periodonto e distúrbios oclusais com a ocorrência de recessão gengival

This study clinically evaluated the relationship of gingival recessions with the periodontal index of gingival and plaque, dental alignment, keratinized mocous, type of periodontal, and occlusal disorders. Study participants were individuals aged between 19 and 33 years. The evaluations were performed by using questionnaires and clinical examinations. In subjects examined, the teeth were assessed and divided into groups (Molars, premolars, canines and incisors). The gingival recession were measured in the central region of the teeth and individuals were subject to disclosure to the plate and observing the poll of plaque and gingival index, respectively. 558 teeth were examined, with 24.1%, 135 had gingival recession greater than or equal to 1mm. Through the combination of tests used to evaluate the average of the recession and its relationship with the variables studied, we observed that the degree of recession of the elements assessed dental showed, almost for the most part, when higher values associated with the index plaque (p = 0.101), Gingival Index (p = 0.053), dental alignment (p = 0.962), width of keratinized mocous (p = 0.004) and type of periodontium (p = 0.033), however statistically significant difference could only be considered when related the recessions in the keratinized mocous and the type of the periodontium. Although we identify, when we evaluate the whole set of teeth that occlusal disturbances (p = 0.002) were more strongly associated with cases of gum recession that the gingival index (p = 0.006), however, these two conditions were correlated with the cases of recession, contributing to its occurrence

Avaliação imuno-histoquímica da BMP-2, BMP-4 e seus receptores (BMPRIA e BMPRII) em ameloblastomas e tumor odontogênico adenomatóide

BMPs are components superfamily ligands transformation growth fator-β (TGF-β) secreted into the extracellular environment, with mechanisms of intercellular communication through specific ligands and receptors in various target cells, being recognized for its influence in osteogenic induction, also play an important role in tissue homeostasis, cell proliferation, differentiation control , in addition to being present in the development of various malignancies. The aim of this study was to compare the immunohistochemical expression of BMP-2, BMP-4 and its receptors BMPRIA and BMPRII in cases of ameloblastoma and adenomatoid odontogenic tumor. The sample consisted of 20 cases of solid ameloblastoma (SA), 10 cases of ameloblastoma unicystic (UA) and 16 cases of adenomatoid odontogenic tumor (AOT). The expression of BMPs and their receptors was evaluated in the parenchyma and stroma of lesions, establishing the percentage of immunopositive cells (0 - negative; 1-1 % to 10 % of cells positive; 2 - 11% to 25% of positive cells; 3 - 26% to 50% of cells positive; 4 - 51% to 75 % of positive cells; 5 - more than 75% positive cells). Analysis of the expression of BMP-2 revealed no statistically significant differences in parenchymal (p = 0.925) and stromal component (p = 0.345) between the groups, as well as BMP-4 (p = 0.873 / p = 0.131). In the epithelial component, SA and AOT had a higher frequency of score 5. In turn, all cases of UA were classified as score 5. The analysis of the stromal component showed no statistically significant difference between groups with respect to median scores BMPRIA positivity (p = 0.768) and BMPRII (p = 0.779). In the epithelial component of SA and UA, no statistically significant correlations between imunoexpression proteins analyzed were observed. In turn, the group of AOT, statistically significant positive correlations between the scores of expression of all studied proteins were found. In the stromal component, statistically significant positive correlations were found only in the SA group in BMP -4 and BMPRII (r = 0.476; p = .034), in the UA in BMP-4 and BMPRIA (r = 0.709; p = 0.022). The results of this study suggest that the BMPs and their receptors are involved in the development process odontogenic tumors. BMP-4, in turn, besides being present in odontogenic tumors have the capacity to form mineralized material.

Resíduos de serviços de saúde na 7ª Região Administrativa do Estado de São Paulo: diagnóstico e proposta de gestão

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A humanização na atenção básica de saúde: visão de um grupo de idosos de Araçatuba-SP

Pós-graduação em Odontologia Preventiva e Social - FOA

A interferência da jornada de trabalho na qualidade do serviço: contribuição á gestão de pessoas

Pós-graduação em Enfermagem (mestrado profissional) - FMB

Perfil de utilização de serviços de saúde no município de Botucatu-SP-2001-2002

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Impacto de intervenção educacional e grupo sobre o consumo de frutas, verduras e legumes de agentes comunitários de saúde do município de Botucatu-SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Inquérito de saúde: condições de vida e usos de serviços de saúde das mães e crianças de Botucatu-SP, 2001-2002

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação dos processos de trabalho dos centros de material e esterização dos hospitais públicos acreditados do estado de São Paulo: um estudo de caso

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influência da atividade física no uso de serviços de saúde da atenção básica de saúde no município de Rio Claro, SP

Introdução: A prevenção e o controle das DCNT’s adquiridas com a prática regular de atividade física podem contribuir para a melhora da saúde dos indivíduos, e consequentemente, pode colaborar na redução do uso dos serviços de saúde e nos gastos referentes a esse serviço além de refletir uma melhor qualidade de vida do indivíduo. Objetivo: 1) Descrever as consultas realizadas pelos participantes do programa e 2)Analisar a influência da atividade física na utilização dos serviços de saúde. Metodologia: Esse trabalho é de caráter retrospectivo e transversal, e foi desenvolvido em Unidades de Saúde da Família no município de Rio Claro, SP. Dentre as 250 mulheres participantes do Programa de exercícios físicos em unidades Básicas de Saúde e Unidades Saúde da Família (USF), com faixa etária acima de 20 anos, foram selecionados dentre essesparticipantes aqueles que possuam prontuários nas sete Unidades Saúde da Família, totalizando 48 prontuários. Foram analisados 1350visitas às unidades no total. Foi analisado o uso dos serviços de saúde através do número de visitas ás unidades de saúde comparando os dados encontrados no ano anterior e no ano posterior do início do programa. Foi utilizado o Termo de Consentimento Livre e Esclarecido para os participantes da pesquisa. Foi realizada análise descritiva dos dados, utilizando-se frequência, média, desvio-padrão máximo e mínimo. Foi realizada análise de comparação dos dados contínuos. Resultados: O grupo participante do Programa Saúde Ativa Rio Claro eram em sua maioria idosos, com alto número de doenças crônicas, principalmente hipertensão (60,4%) e diabetes (37,5%), no entanto, menos da metade com uso de medicamentos para essas doenças. A maioria das consultas eram agendadas (61,7%) ou eram realizadas para triagem/acolhimento (23,0%), com uma menor frequência para controle de pressão arterial ou glicose (5,2%). Os sujeitos analisados...

Efeito da atividade física no uso de serviços de saúde na atenção primária no município de Rio Claro, SP

Introduction: Physical inactivity is identified as the fourth greatest risk factor of mortality worldwide. Little is known about how physical inactivity alters the demand for use of primary health care services, and it is a subject which demands further investigation. Objective: This study aims to determine the influence that physical activity has on the demand for use of primary health care services. Methods: This is a retrospective and cross-sectional study. The Rio Claro Active Health Program (SARC), studied in this research, is a partnership between the Municipal Health Foundation and Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), represented by the Nucleus of Physical Activity, Sport and Health (NAFES) department of Physical Education and coordinated by Prof. Dr. Eduardo Kokubun. The study was carried out on residents of Rio Claro of both sexes seen at SARC. To assess the influence that physical activity had on the demand of the use of health services a questionnaire was given to participants who had attended the program since 2009. This questionnaire contains questions concerning the level of physical activity, health service use, number of both blood pressure and glucose measurement takings, number of spontaneous and scheduled medical visits, number of medications taken, number of illnesses and hospitalizations, comparing the data found in the previous year and the year after the program began. An informed term of consent was used for research participants. Descriptive analysis was carried out, using frequency, mean, maximum and minimum standard deviation. Results: Active participation in The Rio Claro Active Health program has positively influenced the following variables: perception of health, uncontrolled blood pressure, did not modify the number of diseases, number of medications in general, ...(Complete abstract click electronic access below)

Análise de dez anos de utilização de serviços de saúde por uma coorte de pacientes diagnosticados com hipertensão arterial, no CSE - Botucatu, em 1995

The arterial hypertension is a chronic disease, which can be controlled by changing the way of life, as well as by drug treatment, which demand specific Health Care sequence. The lack of adherence to sequence/treatment is one of the main obstacles the disease control. Characterize and analyze the profile of Health Care usage by a 192 patient cohort diagnosed with arterial hypertension in 1995, between the period of 2001 – 2005 and 2006 – 2010. It is a longitudinal study, retrospective and descriptive developed on School Health Center(SHC) which belongs to School of Medicine Botucatu –UNESP, in continuity of the previous research which has analyzed the sequence of the referred sample between the period of 1995 – 1999. The database was obtained from the patients records by using structured adapted forms appointed in the previous study phase. In the case there were transfers to other Health Care facilities, the database was obtained by the records either, while the patients attended the CSE. The database was analyzed by means of descriptive statistics. Predominated the patients in the age from 50 – 69 (47,9%), whites (93,2%), female (56,7%) with low level of education (72,7%). In the period of 2001 - 2005, 76 (39,5%) of the patients remained under sequence, and that 44 (22,9%) belonged to adherence group (GAD), 17 belonged to abandonment/adherent group (GAB/GAD) and 15 to the abandonment group (GAB), groups which were already identified by the study which has analyzed the period of 1995 – 1999. At the end of the third period of the sample sequence (2006 – 2010), 60 (31,2%) of the patients kept under medical sequence. The cohort’s mortality rate in the period reached 15,1% and 21,9% were transferred to other Municipal Health Care facilities. We conclude that the Health Care service usage by the 192 sample’s integrants kept the same model already identified in the previous analysis... (Complete abstract click electronic access below)