493 resultados para Semidry stigma


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Considérant la « nouveauté » du phénomène de dénonciation auprès des policiers et l’utilisation croissante du concept social de « crime motivé par la haine », peu d’études ont été réalisées au Canada sur l’incidence de ces crimes pour les personnes comme pour la société. Cette recherche exploratoire a comme objectif de comprendre la façon dont ce type de crime se distingue des autres manifestations de conflits ou d’incidents et de comprendre les impacts de ce type de victimisation pour les homosexuels en particulier. Plus spécifiquement, ce mémoire vise à approfondir la compréhension du stigmate homosexuel et son impact sur la reportabilité des événements de victimisation criminelle aux autorités judiciaires. Pour ce faire, cinq intervenants communautaires, deux policiers, un avocat et quatre victimes considérant avoir vécu des événements de violence homophobe ont été interviewés. Cet échantillon diversifié a permis de mieux comprendre le phénomène de sous-déclaration des incidents de violences homophobes de la part des victimes et d’obtenir une vue d’ensemble des perceptions des acteurs clés qui peuvent être confrontés au phénomène. L’analyse des entretiens suggère d’importantes lacunes sur le plan de la formation des divers intervenants qui entrainent des difficultés à reconnaître une violence homophobe. Les intervenants confient ne pas se sentir pas suffisamment outillés pour intervenir auprès d’une victime de violence homophobe, n’estiment pas tous posséder les compétences et une compréhension suffisante des réalités des minorités sexuelles, de l'homophobie et de l'hétérosexisme, en somme, l’ensemble des savoirs ultimement nécessaires à une assistance et un accompagnement efficaces pour la déclaration aux autorités d’une telle violence vécue par les victimes. Du côté des victimes de violence(s) homophobe(s), il ressort que la discrimination basée sur l’orientation sexuelle est encore prégnante dans leurs interactions quotidiennes. De leur point de vue, la banalisation et l’impunité de certains comportements homophobes par les instances judiciaires viennent renforcer l’idée chez les victimes et la société d’une forme d’infériorité de l’orientation homosexuelle. L’apposition d’une étiquette homosexuelle paraît ainsi avoir de multiples conséquences psychologiques et sociales sur les victimes, notamment sur leur développement identitaire et sexuel. L’intégration des stigmates homosexuels et l’autostigmatisation, qui les poussent à se déprécier, voire à déprécier l’ensemble de la communauté homosexuelle, surgissent de leur perception de la présence de forts stéréotypes homosexuels, d’une société majoritairement hétérosexiste et de l’opérationnalisation sociale d’une distanciation entre le « nous » hétérosexuel et le « eux » homosexuel. Par leur marginalisation, leur mise en infériorité historique, l’ambiguïté du concept de « crimes motivés par la haine », la noncompréhension de la violence et des répercussions qu’ont les intervenants communautaires et judiciaires de la situation et partant, dans bien des cas, de la prise en charge inadéquate qui en découle pour les victimes des violences homophobes, il est possible de comprendre les appréhensions mentales que les victimes entretiennent ainsi que leur réticence à solliciter de l’aide et encore plus à rapporter la victimisation vécue aux autorités judiciaires.

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Considérant la « nouveauté » du phénomène de dénonciation auprès des policiers et l’utilisation croissante du concept social de « crime motivé par la haine », peu d’études ont été réalisées au Canada sur l’incidence de ces crimes pour les personnes comme pour la société. Cette recherche exploratoire a comme objectif de comprendre la façon dont ce type de crime se distingue des autres manifestations de conflits ou d’incidents et de comprendre les impacts de ce type de victimisation pour les homosexuels en particulier. Plus spécifiquement, ce mémoire vise à approfondir la compréhension du stigmate homosexuel et son impact sur la reportabilité des événements de victimisation criminelle aux autorités judiciaires. Pour ce faire, cinq intervenants communautaires, deux policiers, un avocat et quatre victimes considérant avoir vécu des événements de violence homophobe ont été interviewés. Cet échantillon diversifié a permis de mieux comprendre le phénomène de sous-déclaration des incidents de violences homophobes de la part des victimes et d’obtenir une vue d’ensemble des perceptions des acteurs clés qui peuvent être confrontés au phénomène. L’analyse des entretiens suggère d’importantes lacunes sur le plan de la formation des divers intervenants qui entrainent des difficultés à reconnaître une violence homophobe. Les intervenants confient ne pas se sentir pas suffisamment outillés pour intervenir auprès d’une victime de violence homophobe, n’estiment pas tous posséder les compétences et une compréhension suffisante des réalités des minorités sexuelles, de l'homophobie et de l'hétérosexisme, en somme, l’ensemble des savoirs ultimement nécessaires à une assistance et un accompagnement efficaces pour la déclaration aux autorités d’une telle violence vécue par les victimes. Du côté des victimes de violence(s) homophobe(s), il ressort que la discrimination basée sur l’orientation sexuelle est encore prégnante dans leurs interactions quotidiennes. De leur point de vue, la banalisation et l’impunité de certains comportements homophobes par les instances judiciaires viennent renforcer l’idée chez les victimes et la société d’une forme d’infériorité de l’orientation homosexuelle. L’apposition d’une étiquette homosexuelle paraît ainsi avoir de multiples conséquences psychologiques et sociales sur les victimes, notamment sur leur développement identitaire et sexuel. L’intégration des stigmates homosexuels et l’autostigmatisation, qui les poussent à se déprécier, voire à déprécier l’ensemble de la communauté homosexuelle, surgissent de leur perception de la présence de forts stéréotypes homosexuels, d’une société majoritairement hétérosexiste et de l’opérationnalisation sociale d’une distanciation entre le « nous » hétérosexuel et le « eux » homosexuel. Par leur marginalisation, leur mise en infériorité historique, l’ambiguïté du concept de « crimes motivés par la haine », la noncompréhension de la violence et des répercussions qu’ont les intervenants communautaires et judiciaires de la situation et partant, dans bien des cas, de la prise en charge inadéquate qui en découle pour les victimes des violences homophobes, il est possible de comprendre les appréhensions mentales que les victimes entretiennent ainsi que leur réticence à solliciter de l’aide et encore plus à rapporter la victimisation vécue aux autorités judiciaires.

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Introduction: The segregation of people affected by leprosy in lepercolonies as well as presenting itself ineffective, caused irreversible and irreparable consequences in the lives of individuals who came to carry the marks of stigma and prejudice surrounding the disease. Objective: To identify traits related to the stigma and prejudice in the content of lepers' 12 speeches, separated compulsorily in Saint Francis of Assisi Colony in the city of Natal, located in the state of Rio Grande do Norte. Method: Descriptive study focusing on the oral history of life. The narratives were collected in April 2010 through a recorded interview and analyzed by means of the technique of Thematic Content Analyses. Results: The stigma and the prejudice crystallized in our culture had caused and still cause huge suffering and pain in the participants, who grew up and several aged in biological terms, living with a stigmatizing disease and its complications, sometimes disabling ones. In social and psychological terms, they were discriminated, rejected and even expelled from the familiar conviviality and the original social nucleus. Conclusion: In this manner, one notices the need of these people recover their attachments, values and self-esteem, share feelings and build relationships so as to be integrated in the real world.

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Seizures in some 30% to 40% of patients with epilepsy fail to respond to antiepileptic drugs or other treatments. While much has been made of the risks of new drug therapies, not enough attention has been given to the risks of uncontrolled and progressive epilepsy. This critical review summarizes known risks associated with refractory epilepsy, provides practical clinical recommendations, and indicates areas for future research. Eight international epilepsy experts from Europe, the United States, and South America met on May 4, 2013, to present, review, and discuss relevant concepts, data, and literature on the consequences of refractory epilepsy. While patients with refractory epilepsy represent the minority of the population with epilepsy, they require the overwhelming majority of time, effort, and focus from treating physicians. They also represent the greatest economic and psychosocial burdens. Diagnostic procedures and medical/surgical treatments are not without risks. Overlooked, however, is that these risks are usually smaller than the risks of long-term, uncontrolled seizures. Refractory epilepsy may be progressive, carrying risks of structural damage to the brain and nervous system, comorbidities (osteoporosis, fractures), and increased mortality (from suicide, accidents, sudden unexpected death in epilepsy, pneumonia, vascular disease), as well as psychological (depression, anxiety), educational, social (stigma, driving), and vocational consequences. Adding to this burden is neuropsychiatric impairment caused by underlying epileptogenic processes (essential comorbidities), which appears to be independent of the effects of ongoing seizures themselves. Tolerating persistent seizures or chronic medicinal adverse effects has risks and consequences that often outweigh risks of seemingly more aggressive treatments. Future research should focus not only on controlling seizures but also on preventing these consequences.

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To characterize the recently described SCI1 (stigma/style cell cycle inhibitor 1) gene relationship with the auxin pathway, we have taken the advantage of the Arabidopsis model system and its available tools. At first, we have analyzed the At1g79200 T-DNA insertion mutants and constructed various transgenic plants. The loss- and gain-of-function plants displayed cell number alterations in upper pistils that were controlled by the amino-terminal domain of the protein. These data also confirmed that this locus holds the functional homolog (AtSCI1) of the Nicotiana tabacum SCI1 gene. Then, we have provided some evidences the auxin synthesis/signaling pathways are required for downstream proper AtSCI1 control of cell number: (a) its expression is downregulated in yuc2yuc6 and npy1 auxin-deficient mutants, (b) triple (yuc2yuc6sci1) and double (npy1sci1) mutants mimicked the auxin-deficient phenotypes, with no synergistic interactions, and (c) the increased upper pistil phenotype in these last mutants, which is a consequence of an increased cell number, was able to be complemented by AtSCI1 overexpression. Taken together, our data strongly suggests SCI1 as a component of the auxin signaling transduction pathway to control cell proliferation/differentiation in stigma/style, representing a molecular effector of this hormone on pistil development.

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Universidade Estadual de Campinas . Faculdade de Educação Física

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RATIONALE: Benign focal seizures of adolescence (BFSA) described by Loiseau et al in 1972, is considered a rare entity, but maybe underdiagnosed. Although mild neuropsychological deficits have been reported in patients with benign epilepsies of childhood, these evaluations have not so far been described in BFSA. The aim of this study is to evaluate neuropsychological functions in BFSA with new onset seizures (<12 months). METHODS: Eight patients with BFSA (according to Loiseau et al, 1972, focal or secondarily tonic clonic generalized seizures between the ages of 10-18 yrs., normal neurologic examination, normal EEG or with mild focal abnormalities) initiated in the last 12 months were studied between July 2008 to May 2009. They were referred from the Pediatric Emergency Section of the Hospital Universitário of the University of Sao Paulo, a secondary care regionalized facility located in a district of middle-low income in Sao Paulo city, Brazil. The study was approved by the Ethics Committee of the Institution. All patients performed neurological, EEG, brain CT and neuropsychological evaluation which consisted of Raven's Special Progressive Matrices - General and Special Scale (according to different ages), Wechsler Children Intelligence Scale-WISC III with ACID Profile, Trail Making Test A/B, Stroop Test, Bender Visuo-Motor Test, Rey Complex Figure, Rey Auditory Verbal Learning Test-RAVLT, Boston Naming Test, Fluency Verbal for phonological and also conceptual patterns - FAS/Animals and Hooper Visual Organization Test. For academic achievement, we used a Brazilian test for named "Teste do Desempenho Escolar", which evaluates abilities to read, write and calculate according to school grade. RESULTS: There were 2 boys and 6 girls, with ages ranging from 10 yrs. 9 m to 14 yrs. 3 m. Most (7/8) of the patients presented one to two seizures and only three of them received antiepileptic drugs (AEDs). Six had mild EEG focal abnormalities and all had normal brain CT. All were literate, attended regular public schools and scored in a median range for IQ, and seven showed discrete higher scores for the verbal subtests. There were low scores for attention in different modalities in six patients, mainly in alternated attention as well as inhibitory subtests (Stroop test and Trail Making Test part B). Four of the latter cases who showed impairment both in alternated and inhibitory attention were not taking AEDs. Visual memory was impaired in five patients (Rey Complex Figure). Executive functions analysis showed deficits in working memory in five, mostly observed in Digits Indirect Order and Arithmetic tests (WISC III). Reading and writing skills were below the expected average for school grade in six patients according to the achievement scholar performance test utilized. One patient of this series who had the best scores in all tests was taking phenobarbital. CONCLUSIONS: Neuropsychological imbalance between normal IQ and mild dysfunctions such as in attention domain and in some executive abilities like working memory and planning, as well as difficulties in visual memory and in reading and writing, were described in this group of patients with BFSA from community. This may reflect mild higher level neurological dysfunctions in adolescence idiopathic focal seizures probably caused by an underlying dysmaturative epileptogenic process. Although academic problems often have multiple causes, a specific educational approach may be necessary in these adolescents, in order to improve their scholastic achievements, helping in this way, to decrease the stigma associated to epileptic seizures in the community.

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OBJETIVO: Descrever opiniões e atitudes sobre sexualidade da população urbana brasileira. MÉTODOS: Inquérito de base populacional realizado em 2005, em amostra representativa de 5.040 entrevistados. Realizou-se análise das atitudes diante da iniciação e educação sexual de adolescentes, considerando sexo, idade, escolaridade, renda, estado civil, religião, cor, região geográfica e opiniões sobre fidelidade, homossexualidade e masturbação. Os resultados foram contrastados com pesquisa similar realizada em 1998, sempre que possível. RESULTADOS: A maioria dos entrevistados escolheu como significado para o sexo a alternativa: "sexo é uma prova de amor". Como em 1998, a maioria manifestou-se pela iniciação sexual dos jovens depois do casamento (63,9% para iniciação feminina vs. 52,4% para a masculina), com diferenças entre praticantes das diversas religiões. A educação escolar de adolescentes sobre o uso do preservativo foi apoiada por 97% dos entrevistados, de todos os grupos sociais. Foi elevada a proporção de brasileiros que concordaram com o acesso ao preservativo nos serviços de saúde (95%) e na escola (83,6%). A fidelidade permaneceu um valor quase unânime e aumentou, em 2005, a proporção dos favoráveis à iniciação sexual depois do casamento, assim como a aceitação da masturbação e da homossexualidade, em relação à pesquisa de 1998. As gerações mais novas tendem a ser mais tolerantes e igualitárias. CONCLUSÕES: Como observado em outros países, confirma-se a dificuldade de estabelecer uma dimensão única que explique a regulação da vida sexual ("liberal" vs "conservador"). Sugere-se que a normatividade relativa à atividade sexual deva ser compreendidas à luz da cultura e organização social da sexualidade ao nível local, auscultadas pelos programas de DST/Aids. A opinião favorável ao acesso livre ao preservativo na escola contrasta com resultados mais lentos no âmbito do combate ao estigma e à discriminação das minorias homossexuais. A formulação de políticas laicas dedicadas à sexualidade permitirá o diálogo entre diferentes perspectivas.

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Sexualidade e saúde reprodutiva configuram questões relevantes para o cuidado integral à saúde de pessoas vivendo com HIV. Políticas públicas e serviços de saúde, entretanto, têm dedicado insuficiente atenção ao assunto. O objetivo deste trabalho é compreender como adolescentes e jovens soropositivos lidam com suas experiências sexuais e projetos de namoro, desejo de constituir família e de ter filhos. O estudo qualitativo entrevistou em profundidade 21 adolescentes vivendo com HIV (por transmissão vertical, sexual ou sanguínea) e 13 cuidadores de crianças e jovens, vivendo em São Paulo e em Santos, Brasil. As narrativas descrevem como aprenderam a lidar com a sexualidade e a ansiedade da revelação do diagnóstico nesse contexto. Destacam-se nas narrativas o despreparo, a desinformação sobre prevenção e a falta de apoio para lidar com a situação, assim como o estigma e a discriminação que atravessa grande parte das dificuldades relatadas. O artigo discute criticamente alguns dos desafios postos para uma adequada atenção à questão no Brasil, especialmente a consideração de jovens soropositivos como sujeitos de direitos sexuais, sugerindo diretrizes para a incorporação desta temática a um cuidado integral e humanizado de crianças e jovens vivendo com HIV.

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This study investigated the disclosure of HIV-positive serostatus to sexual partners by heterosexual and bisexual men, selected in centers for HIV/AIDS care. In 250 interviews, we investigated disclosure of serostatus to partners, correlating disclosure to characteristics of relationships. The focus group further explored barriers to maintenance/establishment of partnerships and their association with disclosure and condom use. Fear of rejection led to isolation and distress, thus hindering disclosure to current and new partners. Disclosure requires trust and was more frequent to steady partners, to partners who were HIV-positive themselves, to female partners, and by heterosexuals, occurring less frequently with commercial sex workers. Most interviewees reported consistent condom use. Unprotected sex was more frequent with seropositive partners. Suggestions to enhance comprehensive care for HIV-positive men included stigma management, group activities, and human rights-based approaches involving professional education in care for sexual health, disclosure, and care of "persons living with HIV".

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Neste trabalho propomos questionar como são construídos e validados os discursos acerca de sexualidade, gênero e identidade sexual, a partir da história de vida de três irmãos homossexuais nascidos no interior do nordeste brasileiro. Ainda jovens, migraram para a cidade de Diadema - São Paulo, onde se tornaram, no decorrer de alguns anos, travestis e profissionais do sexo. A percepção da homossexualidade foi relatada como parte da infância, e sentida como uma força natural. Já, as transformações realizadas sobre o corpo decorrentes da travestilidade, a decisão pela prostituição, a orientação sexual (por homem ou por mulher), e a construção de uma identidade sexual (gay ou travesti), apareceram como instâncias dissociadas entre si e relacionadas à busca da valorização pessoal e social diante do estigma atribuído ao gay afeminado, pobre e migrante. A religiosidade afro-brasileira e a gramática yorubá assumiram relevância para a constituição desta possibilidade identitária.

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Este é um estudo descritivo desenvolvido em um município do Estado de São Paulo. Objetivo: identificar e caracterizar as ações do Programa de Controle da Hanseníase nos serviços de saúde municipais. Metodologia: entrevistas gravadas com gestor municipal de saúde e profissionais da assistência à hanseníase. Resultados: a política pública municipal em saúde prioriza o desenvolvimento da atenção básica com ênfase na saúde pública. As ações são realizadas por profissionais capacitados e experientes em hanseníase. Ve rificou-se a não realização da busca ativa dos casos, necessária para o real conhecimento da situação epidemiológica, e das ações de educação em saúde, importante para a redução do estigma e aproximação do sujeito à nova situação de vida e enfrentamento de limitações

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Pomegranate [Punica granatum (Punicaceae)] is characterized by having two types of flowers on the same tree: hermaphroditic bisexual flowers and functionally male flowers. This condition, defined as functional andromonoecy, can result in decreased yields resulting from the inability of male flowers to set fruit. Morphological and histological analyses of bisexual and male flowers were conducted using light and scanning electron microscopy (SEM) to characterize the different flower types observed in pomegranate plants and to better understand their developmental differences. Bisexual flowers had a discoid stigma covered with copious exudate, elongated stigmatic papillae, a single elongate style, and numerous stamens inserted on the inner wall of the calyx tube. Using fluorescence staining, high numbers of pollen tubes were observed growing through a central stylar canal. Ovules were numerous, elliptical, and anatropous. In contrast, male flowers had reduced female parts and exhibited shortened pistils of variable heights. Stigmatic papillae of male flowers had little exudate yet supported pollen germination. However, pollen tubes were rarely observed in styles. Ovules in male flowers were rudimentary and exhibited various stages of degeneration. Pollen from both types of flowers was of similar size, approximate to 20 mu m, and exhibited similar percent germination using in vitro germination assays. Pollen germination was strongly influenced by temperature. Maximal germination (greater than 74%) was obtained at 25 and 35 degrees C; pollen germination was significantly lower at 15 degrees C (58%) and 5 degrees C (10%).

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Method. Participants were 18 years of age or older, who had been discharged from hospitalisation between 6 months and 1 year before the interview, or who underwent reconstructive surgery during the previous year, or who were under outpatient follow-up awaiting reconstructive surgery. Data were collected by means of semi-structured interviews. Results. Thirty-eight of the 44 participants (86.4%) reported some type of changes associated with the burn injury, the treatment, or both, regarding the following aspects: work, leisure, relationships, religious ties, educational activities and habits (smoking, using alcohol and drugs and dressing style). The data showed a statistically significant association between burns on at least one of the upper limbs (with or without hands) and changes in work. Conclusions. Some of the aspects mentioned by the participants, such as work and leisure activities, need to be further researched in order to improve our understanding of the impact that these changes causes in the person`s life.

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The characterization of a coffee gene encoding a protein similar to miraculin-like proteins, which are members of the plant Kunitz serine trypsin inhibitor (STI) family of proteinase inhibitors (PIs), is described. PIs are important proteins in plant defence against insects and in the regulation of proteolysis during plant development. This gene has high identity with the Richadella dulcifica taste-modifying protein miraculin and with the tomato protein LeMir; and was named as CoMir (Coffea miraculin). Structural protein modelling indicated that CoMir had structural similarities with the Kunitz STI proteins, but suggested specific folding structures. CoMir was up-regulated after coffee leaf miner (Leucoptera coffella) oviposition in resistant plants of a progeny derived from crosses between C. racemosa (resistant) and C. arabica (susceptible). Interestingly, this gene was down-regulated during coffee leaf miner herbivory in susceptible plants. CoMir expression was up-regulated after abscisic acid application and wounding stress and was prominent during the early stages of flower and fruit development. In situ hybridization revealed that CoMir transcripts accumulated in the anther tissues that display programmed cell death (tapetum, endothecium and stomium) and in the metaxylem vessels of the petals, stigma and leaves. In addition, the recombinant protein CoMir shows inhibitory activity against trypsin. According to the present results CoMir may act in proteolytic regulation during coffee development and in the defence against L. coffeella. The similarity of CoMir with other Kunitz STI proteins and the role of CoMir in plant development and plant stress are discussed.