Benthic foraminiferal biofacies and stable isotopic record of St. Stephens Quarry, Alabama

We integrate upper Eocene-lower Oligocene lithostratigraphic, magnetostratigraphic, biostratigraphic, stable isotopic, benthic foraminiferal faunal, downhole log, and sequence stratigraphic studies from the Alabama St. Stephens Quarry (SSQ) core hole, linking global ice volume, sea level, and temperature changes through the greenhouse to icehouse transition of the Cenozoic. We show that the SSQ succession is dissected by hiatuses associated with sequence boundaries. Three previously reported sequence boundaries are well dated here: North Twistwood Creek-Cocoa (35.4-35.9 Ma), Mint Spring-Red Bluff (33.0 Ma), and Bucatunna-Chickasawhay (the mid-Oligocene fall, ca. 30.2 Ma). In addition, we document three previously undetected or controversial sequences: mid-Pachuta (33.9-35.0 Ma), Shubuta-Bumpnose (lowermost Oligocene, ca. 33.6 Ma), and Byram-Glendon (30.5-31.7 Ma). An ~0.9 per mil d18O increase in the SSQ core hole is correlated to the global earliest Oligocene (Oi1) event using magnetobiostratigraphy; this increase is associated with the Shubuta-Bumpnose contact, an erosional surface, and a biofacies shift in the core hole, providing a first-order correlation between ice growth and a sequence boundary that indicates a sea-level fall. The d18O increase is associated with a eustatic fall of ~55 m, indicating that ~0.4 per mil of the increase at Oi1 time was due to temperature. Maximum d18O values of Oi1 occur above the sequence boundary, requiring that deposition resumed during the lowest eustatic lowstand. A precursor d18O increase of 0.5 per mil (33.8 Ma, midchron C13r) at SSQ correlates with a 0.5 per mil increase in the deep Pacific Ocean; the lack of evidence for a sea-level change with the precursor suggests that this was primarily a cooling event, not an ice-volume event. Eocene-Oligocene shelf water temperatures of ~17-19 °C at SSQ are similar to modern values for 100 m water depth in this region. Our study establishes the relationships among ice volume, d18O, and sequences: a latest Eocene cooling event was followed by an earliest Oligocene ice volume and cooling event that lowered sea level and formed a sequence boundary during the early stages of eustatic fall.

Modulation of N-methyl-d-aspartate receptor function by glycine transport

The recent discovery of glycine transporters in both the central nervous system and the periphery suggests that glycine transport may be critical to N-methyl-d-aspartate receptor (NMDAR) function by controlling glycine concentration at the NMDAR modulatory glycine site. Data obtained from whole-cell patch–clamp recordings of hippocampal pyramidal neurons, in vitro, demonstrated that exogenous glycine and glycine transporter type 1 (GLYT1) antagonist selectively enhanced the amplitude of the NMDA component of a glutamatergic excitatory postsynaptic current. The effect was blocked by 2-amino-5-phosphonovaleric acid and 7-chloro-kynurenic acid but not by strychnine. Thus, the glycine-binding site was not saturated under the control conditions. Furthermore, GLYT1 antagonist enhanced NMDAR function during perfusion with medium containing 10 μM glycine, a concentration similar to that in the cerebrospinal fluid in vivo, thereby supporting the hypothesis that the GLYT1 maintains subsaturating concentration of glycine at synaptically activated NMDAR. The enhancement of NMDAR function by specific GLYT1 antagonism may be a feasible target for therapeutic agents directed toward diseases related to hypofunction of NMDAR.

Remarks on the life and death of the fam'd Mr. Blood : giving an account [brace]of his plot in Ireland, to surprize Dublin Castle; several transactions in his head-quarters in the city; rescue of Captain Mason at Doncaster; attempt on the person of his Grace the Duke of Ormond; seizing on the crown and scepter in the Tower; coming into favour with his Prince; concern about his Grace the Duke of Buckingham; sickness, death, and twice interment : published for publick information.

Leaf A₂ mis-signed as A₁.

Essai de monographie paroissiale: St.-Georges d'Henryville et la seigneurie de Noyan.

Mode of access: Internet.

Manuscrit venu de St. Hélène, d'une manière inconnue.

Purports to be an autobiography of Napoleon; attributed to Lullin de Chateauvieux. cf. Brit. mus. Cat. and Paris. Bib. nat. Cat. gen.

Commentary on the Gospel of St. John. : With a critical introduction /

Vol. 2-3 translated by M.D. Cusin and S. Taylor.

The antient Syriac version of the Epistles of St. Ignatius to St. Polycarp, the Ephesians, and the Romans : together with extracts from his Epistles, collected from the writings of Severus of Antioch, Timotheus of Alexandria, and others : edited with an English translation and notes : also the Greek text of these three Epistles, corrected according to the authority of the Syriac version /

Text in Syriac, Greek and English.

An illustration of the monastic history and antiquities of the town and abbey of St. Edmund's Bury /

Mode of access: Internet.

Nécrologe de l'abbaye de St. Vaast d'Arras ... publié pour la première fois ...

Mode of access: Internet.

Hugo von St. Victor und die theologischen Richtungen seiner Zeit /

Includes bibliographical references.

The epistle of St. James with an introduction and notes /

Includes bibliographical references and index.

The homilies of S. John Chrysostom, Archbishop of Constantinople, on the Gospel of St. Matthew /

Mode of access: Internet.

Exposition of the Sermon on the Mount : drawn from the writings of St. Augustine ; with observations and an introductory essay on his merits as an interpreter of Scripture /

Includes bibliographical references.

Statistical account of the parish of St. Just, in Penwith, in the county of Cornwall: with some notice of its ecclesiastical and druidical antiquities /

Mode of access: Internet.

The homilies of S. John Chrysostom on the Epistles of St. Paul the Apostle to Timothy, Titus, and Philemon /

Includes indexes.