935 resultados para Praziquantel. Stability. Rheology. Schistosomiasis. Emulsified system


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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Agronomia (Energia na Agricultura) - FCA

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Large areas of Amazonian evergreen forest experience seasonal droughts extending for three or more months, yet show maximum rates of photosynthesis and evapotranspiration during dry intervals. This apparent resilience is belied by disproportionate mortality of the large trees in manipulations that reduce wet season rainfall, occurring after 2-3 years of treatment. The goal of this study is to characterize the mechanisms that produce these contrasting ecosystem responses. A mechanistic model is developed based on the ecohydrological framework of TIN (Triangulated Irregular Network)-based Real Time Integrated Basin Simulator + Vegetation Generator for Interactive Evolution (tRIBS+VEGGIE). The model is used to test the roles of deep roots and soil capillary flux to provide water to the forest during the dry season. Also examined is the importance of "root niche separation," in which roots of overstory trees extend to depth, where during the dry season they use water stored from wet season precipitation, while roots of understory trees are concentrated in shallow layers that access dry season precipitation directly. Observational data from the Tapajo's National Forest, Brazil, were used as meteorological forcing and provided comprehensive observational constraints on the model. Results strongly suggest that deep roots with root niche separation adaptations explain both the observed resilience during seasonal drought and the vulnerability of canopy-dominant trees to extended deficits of wet season rainfall. These mechanisms appear to provide an adaptive strategy that enhances productivity of the largest trees in the face of their disproportionate heat loads and water demand in the dry season. A sensitivity analysis exploring how wet season rainfall affects the stability of the rainforest system is presented. Citation: Ivanov, V. Y., L. R. Hutyra, S. C. Wofsy, J. W. Munger, S. R. Saleska, R. C. de Oliveira Jr., and P. B. de Camargo (2012), Root niche separation can explain avoidance of seasonal drought stress and vulnerability of overstory trees to extended drought in a mature Amazonian forest, Water Resour. Res., 48, W12507, doi:10.1029/2012WR011972.

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Constraints are widely present in the flight control problems: actuators saturations or flight envelope limitations are only some examples of that. The ability of Model Predictive Control (MPC) of dealing with the constraints joined with the increased computational power of modern calculators makes this approach attractive also for fast dynamics systems such as agile air vehicles. This PhD thesis presents the results, achieved at the Aerospace Engineering Department of the University of Bologna in collaboration with the Dutch National Aerospace Laboratories (NLR), concerning the development of a model predictive control system for small scale rotorcraft UAS. Several different predictive architectures have been evaluated and tested by means of simulation, as a result of this analysis the most promising one has been used to implement three different control systems: a Stability and Control Augmentation System, a trajectory tracking and a path following system. The systems have been compared with a corresponding baseline controller and showed several advantages in terms of performance, stability and robustness.

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BACKGROUND: Reproducibility of basic research investigations in homeopathy is challenging. This study investigated if formerly observed effects of homeopathically potentised gibberellic acid (GA3) on growth of duckweed (Lemna gibba L.) were reproducible. METHODS: Duckweed was grown in potencies (14x-30x) of GA3 and one time succussed and unsuccussed water controls. Outcome parameter area-related growth rate was determined by a computerised image analysis system. Three series including five independent blinded and randomised potency experiments (PE) each were carried out. System stability was controlled by three series of five systematic negative control (SNC) experiments. Gibbosity (a specific growth state of L. gibba) was investigated as possibly essential factor for reactivity of L. gibba towards potentised GA3 in one series of potency and SNC experiments, respectively. RESULTS: Only in the third series with gibbous L. gibba L. we observed a significant effect (p = 0.009, F-test) of the homeopathic treatment. However, growth rate increased in contrast to the former study, and most biologically active potency levels differed. Variability in PE was lower than in SNC experiments. The stability of the experimental system was verified by the SNC experiments. CONCLUSIONS: Gibbosity seems to be a necessary condition for reactivity of L. gibba to potentised GA3. Further still unknown conditions seem to govern effect direction and the pattern of active and inactive potency levels. When designing new reproducibility studies, the physiological state of the test organism must be considered. Variability might be an interesting parameter to investigate effects of homeopathic remedies in basic research.

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En el presente trabajo se estudia la producción potencial de biomasa procedente de los cultivos de centeno y triticale en las seis comarcas agrarias de la Comunidad de Madrid (CM) y la posibilidad de su aplicación a la producción de bioelectricidad en cada una de ellas. En primer lugar se realiza un estudio bibliográfico de la situación actual de la bioelectricidad. Uno de los principales datos a tener en cuenta es que en el PER 2011- 2020 se estima que el total de potencia eléctrica instalada a partir de biomasa en España en el año 2020 sea de 1.350 MW, unas dos veces y media la existente a finales de 2010. Además, se comenta el estado de la incentivación del uso de biomasa de cultivos energéticos para producción de electricidad, la cual se regula actualmente según el Real Decreto-ley 9/2013, de 12 de Julio, por el que se adoptaron medidas urgentes para garantizar la estabilidad financiera del sistema eléctrico, y se consideran los criterios de sostenibilidad en el uso de biocombustibles sólidos. Se realiza una caracterización de las seis comarcas agrarias que forman la Comunidad Autónoma de Madrid: Área Metropolitana, Campiña, Guadarrama, Lozoya- Somosierra, Sur-Occidental y Vegas, la cual consta de dos partes: una descripción de la climatología y otra de la distribución de la superficie dedicada a barbecho y cultivos herbáceos. Se hace una recopilación bibliográfica de los modelos de simulación más representativos de crecimiento de los cultivos (CERES y Cereal YES), así como de ensayos realizados con los cultivos de centeno y triticale para la producción de biomasa y de estudios efectuados mediante herramientas GIS y técnicas de análisis multicriterio para la ubicación de centrales de bioelectricidad y el estudio de la logística de la biomasa. Se propone un modelo de simulación de la productividad de biomasa de centeno y de triticale para la CM, que resulta de la combinación de un modelo de producción de grano en base a datos climatológicos y a la relación biomasa/grano media de ambos cultivos obtenida en una experiencia previa. Los modelos obtenidos responden a las siguientes ecuaciones (siendo TN = temperatura media normalizada a 9,9 ºC y PN = precipitación acumulada normalizada a 496,7 mm): - Producción biomasa centeno (t m.s./ha) = 2,785 * [1,078 * ln(TN + 2*PN) + 2,3256] - Producción biomasa triticale (t m.s./ha) = 2,595 * [2,4495 * ln(TN + 2*PN) + 2,6103] Posteriormente, aplicando los modelos desarrollados, se cuantifica el potencial de producción de biomasa de centeno y triticale en las distintas comarcas agrarias de la CM en cada uno de los escenarios establecidos, que se consideran según el uso de la superficie de barbecho de secano disponible (25%, 50%, 75% y 100%). Las producciones potenciales de biomasa, que se podrían alcanzar en la CM utilizando el 100% de la superficie de barbecho de secano, en base a los cultivos de centeno y triticale, se estimaron en 169.710,72 - 149.811,59 - 140.217,54 - 101.583,01 - 26.961,88 y 1.886,40 t anuales para las comarcas de Campiña - Vegas, Sur - Occidental - Área Metropolitana - Lozoya-Somosierra y Guadarrama, respectivamente. Se realiza un análisis multicriterio basado en la programación de compromiso para definir las comarcas agrarias con mejores características para la ubicación de centrales de bioelectricidad en base a los criterios de potencial de biomasa, infraestructura eléctrica, red de carreteras, espacios protegidos y superficie de núcleos urbanos. Al efectuar el análisis multicriterio, se obtiene la siguiente ordenación jerárquica en base a los criterios establecidos: Campiña, Sur Occidental, Vegas, Área Metropolitana, Lozoya-Somosierra y Guadarrama. Mediante la utilización de técnicas GIS se estudia la localización más conveniente de una central de bioelectricidad de 2,2 MW en cada una de las comarcas agrarias y según el uso de la superficie de barbecho de secano disponible (25%, 50%, 75% y 100%), siempre que exista potencial suficiente. Para el caso de la biomasa de centeno y de triticale en base seca se considera un PCI de 3500 kcal/kg, por lo que se necesitarán como mínimo 17.298,28 toneladas para satisfacer las necesidades de cada una de las centrales de 2,2 MW. Se analiza el potencial máximo de bioelectricidad en cada una de las comarcas agrarias en base a los cultivos de centeno y triticale como productores de biomasa. Según se considere el 25% o el 100% del barbecho de secano para producción de biomasa, la potencia máxima de bioelectricidad que se podría instalar en cada una de las comarcas agrarias variaría entre 5,4 y 21,58 MW en la comarca Campiña, entre 4,76 y 19,05 MW en la comarca Vegas, entre 4,46 y 17,83 MW en la comarca Sur Occidental, entre 3,23 y 12,92 MW en la comarca Área Metropolitana, entre 0,86 y 3,43 MW en la comarca Lozoya Somosierra y entre 0,06 y 0,24 MW en la comarca Guadarrama. La potencia total que se podría instalar en la CM a partir de la biomasa de centeno y triticale podría variar entre 18,76 y 75,06 MW según que se utilice el 25% o el 100% de las tierras de barbecho de secano para su cultivo. ABSTRACT In this work is studied the potential biomass production from rye and triticale crops in the six Madrid Community (MC) agricultural regions and the possibility of its application to the bioelectricity production in each of them. First is performed a bibliographical study of the current situation of bioelectricity. One of the main elements to be considered is that in the PER 2011-2020 is estimated that the total installed electric power from biomass in Spain in 2020 was 1.350 MW, about two and a half times as at end 2010. Also is discussed the status of enhancing the use of biomass energy crops for electricity production, which is currently regulated according to the Real Decreto-ley 9/2013, of July 12, by which urgent measures were adopted to ensure financial stability of the electrical system, and there are considered the sustainability criteria in the use of solid biofuels. A characterization of the six Madrid Community agricultural regions is carried out: Area Metropolitana, Campiña, Guadarrama, Lozoya-Somosierra, Sur-Occidental and Vegas, which consists of two parts: a description of the climatology and another about the distribution of the area under fallow and arable crops. It makes a bibliographic compilation of the most representative crop growth simulation models (CERES and Cereal YES), as well as trials carried out with rye and triticale crops for biomass production and studies conducted by GIS tools and techniques multicriteria analysis for the location of bioelectricity centrals and the study of the logistics of biomass. Is proposed a biomass productivity simulation model for rye and triticale for MC that results from the combination of grain production model based on climatological data and the average relative biomass/grain of both crops obtained in a prior experience. The models obtained correspond to the following equations (where TN = normalized average temperature and PN = normalized accumulated precipitation): - Production rye biomass (t d.m./ha) = 2.785 * [1.078 * ln (TN + 2*PN) + 2.3256] - Production triticale biomass (t d.m./ha) = 2,595 * [2.4495 * ln (TN + 2*PN) + 2.6103] Subsequently, applying the developed models, the biomass potential of the MC agricultural regions is quantified in each of the scenarios established, which are considered as the use of dry fallow area available (25%, 50%, 75 % and 100%). The potential biomass production that can be achieved within the MC using 100% of the rainfed fallow area based on rye and triticale crops, were estimated at 169.710,72 - 149.811,59 - 140.217,54 - 101.583,01 - 26.961,88 and 1.886,40 t annual for the regions of Campiña, Vegas, Sur Occidental, Area Metropolitana, Lozoya- Somosierra and Guadarrama, respectively. A multicriteria analysis is performed, based on compromise programming to define the agricultural regions with better features for the location of bioelectricity centrals, on the basis of biomass potential, electrical infrastructure, road network, protected areas and urban area criteria. Upon multicriteria analysis, is obtained the following hierarchical order based on criteria: Campiña, Sur Occidental, Vegas, Area Metropolitana, Lozoya-Somosierra and Guadarrama. Likewise, through the use of GIS techniques, the most suitable location for a 2,2 MW bioelectricity plant is studied in each of the agricultural regions and according to the use of dry fallow area available (25%, 50% , 75% and 100%), if there is sufficient potential. In the case of biomass rye and triticale dry basis is considered a PCI of 3500 kcal/kg, so it will take at least 17,298.28 t to satisfy the needs of each plant. Is analyzed the maximum bioelectricity potential on each of the agricultural regions on the basis of the rye and triticale crops as biomass producers. As deemed 25% or 100% dry fallow for biomass, the maximum bioelectricity potential varies between 5,4 and 21,58 MW in the Campiña region, between 4,76 and 19,05 MW in the Vegas region, between 4,46 and 17,83 MW in the Sur Occidental region, between 3,23 and 12,92 MW in the Area Metropolitana region, between 0,86 and 3,43 MW in the Lozoya-Somosierra region and between 0,06 and 0,24 MW in the Guadarrama region. The total power that could be installed in the CM from rye and triticale biomass could vary between 18.76 and 75.06 MW if is used the 25% or 100% of fallow land for rainfed crop.

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Cuando la separación física entre el sistema local y remoto es relativamente corta, el retardo no es perceptible; sin embargo, cuando el manipulador local y el manipulador remoto se encuentran a una distancia lejana uno del otro, el retardo de tiempo ya no es insignificante e influye negativamente en la realización de la tarea. El retardo de tiempo en un sistema de control introduce un atraso de fase que a su vez degrada el rendimiento del sistema y puede causar inestabilidad. Los sistemas de teleoperación pueden sacar provecho de la posibilidad de estar presente en dos lugares simultáneamente, sin embargo, el uso de Internet y otras redes de conmutación de paquetes, tales como Internet2, impone retardos de tiempo variables, haciendo que los esquemas de control ya establecidos elaboren soluciones para hacer frente a inestabilidades causadas por estos retardos de tiempo variables. En este trabajo de tesis se presenta el modelado y análisis de un sistema de teloperación bilateral no lineal de n grados de libertad controlado por convergencia de estado. La comunicación entre el sitio local y remoto se realiza mediante un canal de comunicación con retardo de tiempo. El análisis presentado en este trabajo considera que el retardo puede ser constante o variable. Los principales objetivos de este trabajo son; 1) Desarrollar una arquitectura de control no lineal garantizando la estabilidad del sistema teleoperado, 2) Evaluar la estabilidad del sistema considerando el retardo en la comunicación, y 3) Implementación de los algoritmos desarrollados para probar el desempeño de los mismos en un sistema experimental de 3 grados de libertad. A través de la teoría de Estabilidad de Lyapunov y el funcional Lyapunov-Krasovskii, se demuestra que el sistema de lazo cerrado es asintóticamente estable. Estas conclusiones de estabilidad se han obtenido mediante la integración de la función de Lyapunov y aplicando el Lema de Barbalat. Se demuestra también que se logra sincronizar las posiciones del manipulador local y remoto cuando el operador humano no mueve el manipulador local y el manipulador remoto se mueve libremente. El esquema de control propuesto se ha validado mediante simulación y en forma experimental empleando un sistema de teleoperación real desarrollado en esta tesis doctoral y que consta de un un manipulador serie planar de tres grados de libertad, un manipulador local, PHANTOM Omni, el cual es un dispositivo haptico fabricado que consta de 3 grados de libertad (en fuerza) y que proporciona realimentación de fuerza en los ejes x,y,z. El control en tiempo real se ha diseñado usando el Sistema Operativo en Tiempo Real QuaRC de QUARC en el lado local y el Simulink Real-Time Windows TargetTM en el lado remoto. Para finalizar el resumen se destaca el impacto de esta tesis en el mundo científico a través de los resultados publicados: 2 artículos en revistas con índice de impacto , 1 artículo en una revista indexada en Sistemas, Cibernética e Informática, 7 artículos en congresos y ha obtenido un premio en la 9a. Conferencia Iberoamericana en Sistemas, Cibernética e Informática, 2010. ABSTRACT When the physical separation between the local and remote system is relatively short, the delay is not noticeable; however, when the local manipulator and the remote manipulator are at a far distance from each other, the time delay is no longer negligible and negatively influences the performance of the task. The time delay in a control system introduces a phase delay which in turn degrades the system performance and cause instability. Teleoperation systems can benefit from the ability to be in two places simultaneously, however, the use of Internet and other packet switched networks, such as Internet2, imposes varying time delays, making established control schemes to develop solutions to address these instabilities caused by different time delays. In this thesis work we present a modeling and analysis of a nonlinear bilateral teloperation system of n degrees of freedom controlled by state convergence strategy. Communication between the local and remote site is via a communication channel with time delay. The analysis presented in this work considers that the time-delay can be constant or variable. The main objectives of this work are; 1) Develop a nonlinear control schemes to ensure the stability of the teleoperated system, 2) Evaluate the system stability considering the delay in communication, and 3) Implementation of algorithms developed to test the performance of the teleoperation system in an experimental system of 3 degrees of freedom. Through the Theory of Stability of Lyapunov and the functional Lyapunov-Krasovskii, one demonstrates that the closed loop system is asymptotically stable.. The conclusions about stability were obtained by integration of the Lyapunov function and applying Barbalat Lemma. It further shows that the positions of the local and remote manipulator are synchronize when the human operator stops applying a constant force and the remote manipulator does not interact with the environment. The proposed control scheme has been validated by means of simulation and in experimental form using a developed system of real teleoperation in this doctoral thesis, which consists of a series planar manipulator of three degrees of freedom, a local manipulator, PHANTOM Omni, which is an haptic device that consists of 3 degrees of freedom (in force) and that provide feeback force in x-axis, and, z. The control in real time has been designed using the Operating system in Real time QuaRC of Quanser in the local side and the Simulink Real-Time Windows Target in the remote side. In order to finalize the summary, the highlights impact of this thesis in the scientific world are shows through the published results: 2 articles in Journals with impact factor, one article in a indexed Journal on Systemics, Cybernetics and Informatics, 7 articles in Conferences and has won an award in 9a. Conferencia Iberoamericana en Sistemas, Cibernética e Informática, 2010.

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These last years, in multiple Member States, the electricity markets have seen the rapid emergence of Capacity Remuneration Mechanisms (CRMs). They are meant to guarantee the stability of the electricity system in a more uncertain context. The reactions of the European Commission were late towards them. It is thus essential to bring some clarity here, otherwise the legal uncertainty could become a new impediment for investment.

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Thesis (Master's)--University of Washington, 2016-06

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The low index Magnesium hydride surfaces, MgH2(001) and MgH2(110), have been studied by ab intio Density Functional Theory (DFT) calculations. It was found that the MgH2(110) surface is more stable than MgH2(001) surface, which is in good agreement with the experimental observation. The H-2 desorption barriers vary depending on the crystalline surfaces that are exposed and also the specific H atom sites involved-they are found to be generally high, due to the thermodynamic stability of the MgH2, system, and are larger for the MgH2(001) surface. The pathway for recombinative desorption of one in-plane and one bridging H atom from the MgH2(110) surface was found to be the lowest energy barrier amongst those computed (172 KJ/mol) and is in good agreement with the experimental estimates. (c) 2006 Elsevier B.V. All rights reserved.

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We propose the design of a novel ?-shaped fiber laser resonator and apply it to build a long-cavity normaldispersion mode-locked Er-fiber laser which features enhanced functionalities for management and optimization of pulsed lasing regimes. We report the generation of sub-nanosecond pulses with the energy of ~0.5 µJ at a kilohertz-scale repetition rate in an all-fiber system based on the new laser design. A combination of special design solutions in the laser, such as polarization instability compensation in the ultra-long arm of the resonator, intra-cavity spectral selection of radiation with a broadband fiber Bragg grating, and polarization selection by means of a tilted refractive index grating, ensures low amplified spontaneous emission (ASE) noise and high stability of the laser system output parameters.

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We propose the design of a novel ?-shaped fiber laser resonator and apply it to build a long-cavity normaldispersion mode-locked Er-fiber laser which features enhanced functionalities for management and optimization of pulsed lasing regimes. We report the generation of sub-nanosecond pulses with the energy of ~0.5 µJ at a kilohertz-scale repetition rate in an all-fiber system based on the new laser design. A combination of special design solutions in the laser, such as polarization instability compensation in the ultra-long arm of the resonator, intra-cavity spectral selection of radiation with a broadband fiber Bragg grating, and polarization selection by means of a tilted refractive index grating, ensures low amplified spontaneous emission (ASE) noise and high stability of the laser system output parameters.

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This paper first explores the polarizationthesis, according to which between 1990-2010 political polarization increased to a large extent in the Hungarian political elite and among citizens, although it did not undermine the stability of the political system. Second, it gives an endogenousexplanation for this phenomenon. Third, through theoretical discussion and empirical examples taken from Hungarian politics it is revealed that although growing polarization has not generated regime instability, it reduces, or might reduce, the efficiency of the operation of democracy. Five mechanisms of the effects of ideological polarization which weaken democratic accountability are explored.

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Modern power networks incorporate communications and information technology infrastructure into the electrical power system to create a smart grid in terms of control and operation. The smart grid enables real-time communication and control between consumers and utility companies allowing suppliers to optimize energy usage based on price preference and system technical issues. The smart grid design aims to provide overall power system monitoring, create protection and control strategies to maintain system performance, stability and security. This dissertation contributed to the development of a unique and novel smart grid test-bed laboratory with integrated monitoring, protection and control systems. This test-bed was used as a platform to test the smart grid operational ideas developed here. The implementation of this system in the real-time software creates an environment for studying, implementing and verifying novel control and protection schemes developed in this dissertation. Phasor measurement techniques were developed using the available Data Acquisition (DAQ) devices in order to monitor all points in the power system in real time. This provides a practical view of system parameter changes, system abnormal conditions and its stability and security information system. These developments provide valuable measurements for technical power system operators in the energy control centers. Phasor Measurement technology is an excellent solution for improving system planning, operation and energy trading in addition to enabling advanced applications in Wide Area Monitoring, Protection and Control (WAMPAC). Moreover, a virtual protection system was developed and implemented in the smart grid laboratory with integrated functionality for wide area applications. Experiments and procedures were developed in the system in order to detect the system abnormal conditions and apply proper remedies to heal the system. A design for DC microgrid was developed to integrate it to the AC system with appropriate control capability. This system represents realistic hybrid AC/DC microgrids connectivity to the AC side to study the use of such architecture in system operation to help remedy system abnormal conditions. In addition, this dissertation explored the challenges and feasibility of the implementation of real-time system analysis features in order to monitor the system security and stability measures. These indices are measured experimentally during the operation of the developed hybrid AC/DC microgrids. Furthermore, a real-time optimal power flow system was implemented to optimally manage the power sharing between AC generators and DC side resources. A study relating to real-time energy management algorithm in hybrid microgrids was performed to evaluate the effects of using energy storage resources and their use in mitigating heavy load impacts on system stability and operational security.