Kurtze Lebens Verfassung deren von Heiligkeit weltberühmten der löbl. Gold- und Silber-Arbeither Kunst-Verwandten fünff heiligen Männern: Eligii, Tylonis, Anastasii, Andronici und Facii ... in offentlichen Druck befördert durch die drey Prager Städte des Königreichs Böhmen, dermahlen sich befindende Khunst-Verwandten Gold- und Silber-Arbeithern.

Translation of his Compendio delle vite de santi orefici ed argentieri.

Prager Medicinische Wochenschrift, corrospondenzblatt der deutschen ärzte Böhmon: 1.-40. jahrg., 1876-juni 30, 1915.

No more published.

Prager tierärztliche archiv. Fachblatt der sudetendeutschen tierärzte

Title varies.

Geschichte des Prager theaters. Von den anfängen des schauspielwesens bis auf die neueste zeit.

Mode of access: Internet.

Ausgeführte Bauornamente von Prager Bildhauern.

Ilustrated t.-p.

Johann Faust, ein allegorisches drama von fůnf aufzůgen ... Zum erstenmahl aufgefůhrt auf der Ko̊nigl. Prager schaubůhne von der von Brunianischen gesellschaft. 1775 ...

"Dieses buch wurde...in einer einmaligen auflage von 500 exemplaren auf einem der vorlage genau entsprechenden, eigens dazu hergestellten handschöpften papiere gedruckt..." This copy numbered.

Kursachsen und die Durchfuhrung des Prager Friedens 1635.

Thesis (doctoral)--Universitat Leipzig.

Die Jesuiten und die Friedensfrage in der Zeit vom Prager Frieden bis zum Nurnberger Friedensexekutionshauptrezess 1635-1650 : erster Teil.

Thesis (doctoral)--Ludwig-Maximilians-Universitat zu Munchen.

Prager Studien aus dem Gebiete der classischen Alterthumswissenschaft

Mode of access: Internet.

Geschichte der Prager Universität. Zur Feier der fünfhundertjährigen Gründung derselben,

Mode of access: Internet.

Miniaturgemälde von Prag : neuester Prager Taschen-Wegweiser und alphabetischer Auskunfts-Sekretär : zur schnellen und genauen Orientirung im Bereiche aller Denk-, Sehens- und Wissenswürdigkeiten Prags und seiner nahen und fernen Umgebungen, nebst Eisenbahntouren etc. : für Fremde und Einheimische : mit 12 Prospekten, sämmtlich in Stahl gestochen; der Situationsplan, ebenfalls in Stahlstich, ist aparte zu haben

verfasst von Dr. Legis Glückselig

The effect of friction on indenter force and pile-up in numerical simulations of bone nanoindentation

Nanoindentation is a useful technique for probing the mechanical properties of bone, and finite element (FE) modeling of the indentation allows inverse determination of elasto-plastic constitutive properties. However, FE simulations to date have assumed frictionless contact between indenter and bone. The aim of this study was to explore the effect of friction in simulations of bone nanoindentation. Two dimensional axisymmetric FE simulations were performed using a spheroconical indenter of tip radius 0.6m and angle 90°. The coefficient of friction between indenter and bone was varied between 0.0 (frictionless) and 0.3. Isotropic linear elasticity was used in all simulations, with bone elastic modulus E=13.56GPa and Poisson’s ratio =0.3. Plasticity was incorporated using both Drucker-Prager and von Mises yield surfaces. Friction had a modest effect on the predicted force-indentation curve for both von Mises and Drucker-Prager plasticity, reducing maximum indenter displacement by 10% and 20% respectively as friction coefficient was increased from zero to 0.3 (at a maximum indenter force of 5mN). However, friction has a much greater effect on predicted pile-up after indentation, reducing predicted pile-up from 0.27m to 0.11m with a von Mises model, and from 0.09m to 0.02m with Drucker-Prager plasticity. We conclude that it is important to include friction in nanoindentation simulations of bone.

The effect of friction on indenter force and pile-up in numerical simulations of bone nanoindentation

Nanoindentation is a useful technique for probing the mechanical properties of bone, and finite element (FE) modeling of the indentation allows inverse determination of elasto-plastic constitutive properties. However, all but one FE study to date have assumed frictionless contact between indenter and bone. The aim of this study was to explore the effect of friction in simulations of bone nanoindentation. Two dimensional axisymmetric FE simulations were performed using a spheroconical indenter of tip radius 0.6 m and angle 90°. The coefficient of friction between indenter and bone was varied between 0.0 (frictionless) and 0.3. Isotropic linear elasticity was used in all simulations, with bone elastic modulus E=13.56GPa and Poisson‟s ratio f 0.3. Plasticity was incorporated using both Drucker-Prager and von Mises yield surfaces. Friction had a modest effect on the predicted force-indentation curve for both von Mises and Drucker-Prager plasticity, reducing maximum indenter displacement by 10% and 20% respectively as friction coefficient was increased from zero to 0.3 (at a maximum indenter force of 5mN). However, friction has a much greater effect on predicted pile-up after indentation, reducing predicted pile-up from 0.27 to 0.11 m with a von Mises model, and from 0.09 to 0.02 m with Drucker-Prager plasticity. We conclude that it is potentially important to include friction in nanoindentation simulations of bone if pile-up is used to compare simulation results with experiment.

The importance of reporting housing and husbandry in rat research

In 1963, the National Institutes of Health (NIH) first issued guidelines for animal housing and husbandry. The most recent 2010 revision emphasizes animal care “in ways judged to be scientifically, technically, and humanely appropriate” (National Institutes of Health, 2010, p. XIII). The goal of these guidelines is to ensure humanitarian treatment of animals and to optimize the quality of research. Although these animal care guidelines cover a substantial amount of information regarding animal housing and husbandry, researchers generally do not report all these variables (see Table ​Table1).1). The importance of housing and husbandry conditions with respect to standardization across different research laboratories has been debated previously (Crabbe et al., 1999; Van Der Staay and Steckler, 2002; Wahlsten et al., 2003; Wolfer et al., 2004; Van Der Staay, 2006; Richter et al., 2010, 2011). This paper focuses on several animal husbandry and housing issues that are particularly relevant to stress responses in rats, including transportation, handling, cage changing, housing conditions, light levels and the light–dark cycle. We argue that these key animal housing and husbandry variables should be reported in greater detail in an effort to raise awareness about extraneous experimental variables, especially those that have the potential to interact with the stress response.

Regulation of the Fear Network by Mediators of Stress: Norepinephrine Alters the Balance between Cortical and Subcortical Afferent Excitation of the Lateral Amygdala

Pavlovian auditory fear conditioning involves the integration of information about an acoustic conditioned stimulus (CS) and an aversive unconditioned stimulus in the lateral nucleus of the amygdala (LA). The auditory CS reaches the LA subcortically via a direct connection from the auditory thalamus and also from the auditory association cortex itself. How neural modulators, especially those activated during stress, such as norepinephrine (NE), regulate synaptic transmission and plasticity in this network is poorly understood. Here we show that NE inhibits synaptic transmission in both the subcortical and cortical input pathway but that sensory processing is biased toward the subcortical pathway. In addition binding of NE to β-adrenergic receptors further dissociates sensory processing in the LA. These findings suggest a network mechanism that shifts sensory balance toward the faster but more primitive subcortical input