Auburn

kuv., 15 x 23 cm

Receptor localization of steroid hormones and drugs: discoveries through the use of thaw-mount and dry-mount autoradiography

The history of receptor autoradiography, its development and applications, testify to the utility of this histochemical technique for localizing radiolabeled hormones and drugs at cellular and subcellular sites of action in intact tissues. Localization of diffusible compounds has been a challenge that was met through the introduction of the "thaw-mount" and "dry-mount" autoradiographic techniques thirty years ago. With this cellular receptor autoradiography, used alone or combined with other histochemical techniques, sites of specific binding and deposition in vivo and in vitro have been characterized. Numerous discoveries, some reviewed in this article, provided information that led to new concepts and opened new areas of research. As an example, in recent years more than fifty target tissues for vitamin D have been specified, challenging the conventional view about the main biological role of vitamin D. The functions of most of these vitamin D target tissues are unrelated to the regulation of systemic calcium homeostasis, but pertain to the (seasonal) regulation of endo- and exocrine secretion, cell proliferation, reproduction, neural, immune and cardiovascular responses, and adaptation to stress. Receptor autoradiography with cellular resolution has become an indispensable tool in drug research and development, since information can be obtained that is difficult or impossible to gain otherwise

Cemetery Committee Reports, Welland County, 1946

In 1946 the cemetery committee reported at least twice to the Welland County council. The reports included the state of cemeteries within the county boundaries and recommendations for grants to be made for their maintenance. The committee consisted of George F. Broadley, Chairman, and Herbert T. Guess, Irvin Edward Michener and Ellis P. Morningstar.

Brown Bess Socket Mount Bayonet

This original Brown Bess socket mount bayonet is vintage War of 1812. It was purchased in the Niagara area and likely has a long local provenance.

The 19th Century Tombstone Database Project Records, 1790-1890 (non-inclusive)

The 19th Century Tombstone Database project was funded by the program Federal Summer Youth Employment scheme in the summer of 1982 and led by Dr. David W. Rupp, a Professor at the Classics Department, Brock University. The main goal of the project was to collect information related to various cemeteries in Niagara region and burials that took place from 1790-1890. Data was collected and presented in the form of data summary forms of persons, tombstone sketches, photographs of tombstones, maps, and computer printouts. The materials created as a result of a research completed for the 19th Century Tombstone Database project are important as a number of the tombstones have been damaged or gone missing since the research was finished. Before Dr. Rupp retired from Brock University, he donated project materials to the Brock University Special Collections and Archives.

Notice of Location of Grave - Wailly Orchard Cemetery

Two notices from the Director of Graves Registration and Enquiries, London, England noting the location of the grave as Wailly Orchard Cemetery near Arras. One of the certificates incorrectly notes the name as S.G. Woodruff while the other correctly has S. D. Woodruff. The number listed for Lieut. S. D. Woodruff's grave site photograph is CCM/9/4433.

Indenture St. Catharines Cemetery

Indenture with the letterhead “St. Catharines Cemetery” (this is a photocopy) between the rector and church wardens of St. George’s Church, St. Catharines and Ann S. Sanderson of St. Catharines. The deed is for 208 square feet commencing at a lot purchased by S.D. Woodruff in part of section P – cemetery deed no. is 134, Jan. 23, 1861.

Indenture St. Catharines Cemetery

Indenture with the letterhead “St. Catharines Cemetery” between the rector and church wardens of St. George’s Church, St. Catharines and Henry C. Woodruff of the Township of Niagara. The deed is for 538 square feet in Lots 1 and 2 in division no. 13 in section M of the St. Catharines Cemetery. The cemetery deed no. is 530, July 7, 1869.

Indenture St. Catharines Cemetery

Indenture with the letterhead “St. Catharines Cemetery” between the Town Council of St. Catharines and Joel Phelps of St. Catharines. The deed is for 108 square feet for Lot no.3 in division 3 in section P of the St. Catharines Cemetery. The deed no. is 847, June 11, 1874.

Indenture between St. Catharines Cemetery of the Corporation of the City of St. Catharines and Samuel D. Woodruff

Indenture between St. Catharines Cemetery of the Corporation of the City of St. Catharines and Samuel D. Woodruff, cemetery deed no. 1253, May 18, 1883.

Indenture between Victoria Lawn Cemetery of the Corporation of the City of St. Catharines and Samuel D. Woodruff

Indenture between Victoria Lawn Cemetery of the Corporation of the City of St. Catharines and Samuel D. Woodruff for 112 sq.ft. known as part of section P. This is deed no. 1905, Oct. 21, 1901.

Indenture between Victoria Lawn Cemetery of the Corporation of the City of St. Catharines and Hamilton K. Woodruff

Indenture between Victoria Lawn Cemetery of the Corporation of the City of St. Catharines and Hamilton K. Woodruff for 216 square feet, Lot no.2 in division 9, section G of the Victoria Lawn Cemetery. This is a handwritten copy. The deed no. is 1937, Jan. 6, 1903.

Indenture between Victoria Lawn Cemetery, St. Catharines and H.K. Woodruff

Indenture between Victoria Lawn Cemetery, St. Catharines and H.K. Woodruff for Lot no. 1 in the north part in section L which included 108 feet. This is cemetery deed no. 261, March 8, 1910.

Indenture Park Lawn Cemetery Co. Ltd.

Indenture between Park Lawn Cemetery Co. Ltd. of Toronto, deed no.2905 for Lot 91 in section H for 156 feet for burial ground paid by Percy C. Bands [Band], Feb. 24, 1926.

Indenture between St. Catharines Victoria Lawn Cemetery and Mrs. H.K. Woodruff

Indenture between St. Catharines Victoria Lawn Cemetery and Mrs. H.K. Woodruff for a perpetual care fund and $67.20 into a general care and improvement fund in respect to the southerly portion of Lot no.9 in section P of the St. Catharines Victoria Lawn Cemetery. The deed no. is 859. This is the S.D. Woodruff plot, Nov. 4, 1932.