Diagnóstico del desarrollo de la terapia manual en Colombia

Este trabajo nace de la inquietud de las autoras durante su proceso de formación académica en Terapia Manual por conocer el estado de ésta a nivel profesional, laboral, académico, personal y de agremiación a lo largo de estos seis años de aplicación en Colombia. Para ello, se recopiló la base de datos de los egresados de la Escuela Colombiana de Rehabilitación y de la Universidad del Rosario donde se obtuvieron 12 y 46 registros respectivamente., los cuales fueron contactados por medio de correo electrónico, telefónicamente (llamada local, nacional y celular), correo certificado y personalmente. Se les aplicó un formulario de recolección de información donde plasmaron sus experiencias profesionales y personales relacionadas con la especialidad.

Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products

The metabolism of chlorogenic acid., naringin, and rutin, representative members of three common families of dietary polyphenols, the hydroxycinnamates, the flavanones, and the flavonols, respectively, was studied in an in vitro mixed culture model of the human colonic microflora. Time- and concentration-dependent degradation of all three compounds was observed, which was associated with the following metabolic events after cleavage of the ester or glycosidic bond: reduction of the aliphatic double bond of the resulting hydroxycinnamate caffeic acid residue; dehydroxylation and ring fission of the heterocyclic C-ring of the resulting deglycosylated flavanone, naringenin, and of the deglycosylated flavonol, quercetin (which differed depending on the substitution). The metabolic events, their sequences, and major phenolic end products, as identified by GC-MS or LC-MS/MS, were elucidated from the structural characteristics of the investigated compounds. The major phenolic end products identified were 3-D-hydroxyphenyl)propionic acid for chlorogenic acid, 3-(4-hydroxyphenyl)-propionic acid and 3-phenylpropionic acid for naringin, and 3-hydroxyphenylacetic acid and 3-(3-hydroxyphenyl)-propionic acid for rutin. The degree of degradation of the compounds studied was significantly influenced by the substrate concentration as well as individual variations in the composition of the fecal flora. The results support extensive metabolism of dietary polyphenols in the colon, depending on substrate concentration and residence time, with resultant formation of simple phenolics, which can be considered biomarkers of colonic metabolism if subsequently absorbed. It is also apparent that a relatively small number of phenolic degradation products are formed in the colon from the diverse group of natural polyphenols. (C) 2003 Elsevier Inc. All rights reserved.

The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans

Dietary nitrate is metabolized to nitrite by bacterial flora on the posterior surface of the tongue leading to increased salivary nitrite concentrations. In the acidic environment of the stomach, nitrite forms nitrous acid, a potent nitrating/nitrosating agent. The aim of this study was to examine the pharmacokinetics of dietary nitrate in relation to the formation of salivary, plasma, and urinary nitrite and nitrate in healthy subjects. A secondary aim was to determine whether dietary nitrate increases the formation of protein-bound 3-nitrotyrosine in plasma, and if dietary nitrate improves platelet function. The pharmacokinetic profile of urinary nitrate excretion indicates total clearance of consumed nitrate in a 24 h period. While urinary, salivary, and plasma nitrate concentrations increased between 4- and 7-fold, a significant increase in nitrite was only detected in saliva (7-fold). High dietary nitrate consumption does not cause a significant acute change in plasma concentrations of 3-nitrotyrosine or in platelet function.

Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice

Infiltration of macrophages into the artery wall plays detrimental roles during hypertension by promoting vascular inflammation and endothelial dysfunction, and it occurs via a chemo-attractant action of chemokines on macrophage cytokine receptors. We sought to identify the key chemokine receptors associated with macrophage infiltration into the vascular wall during deoxycorticosterone acetate (DOCA)/salt-induced hypertension in mice and to evaluate the impact of pharmacological inhibition of these receptors on blood pressure and leukocyte accumulation. Mice treated with DOCA/salt for 21 days displayed markedly elevated systolic blood pressure (158±2 versus 114±5 mm Hg in sham group; P<0.0001). Polymerase chain reaction screening via a gene array of 20 chemokine receptors indicated an increased expression of CCR2 in aortas of DOCA/salt-treated mice. Real-time polymerase chain reaction confirmed mRNA upregulation of CCR2 in aortas from DOCA/salt-treated animals and of the CCR2 ligands CCL2, CCL7, CCL8, and CCL12 (all >2-fold versus sham; P<0.05). Flow cytometry revealed 2.9-fold higher macrophage numbers (ie, CD45+ CD11b+ F4/80+ cells) in the aortic wall of DOCA/salt versus sham-treated mice. Intervention with a CCR2 antagonist, INCB3344 (30 mg/kg per day, IP), 10 days after the induction of hypertension with DOCA/salt treatment, reduced the aortic expression of CCR2 mRNA and completely reversed the DOCA/salt-induced influx of macrophages. Importantly, INCB3344 substantially reduced the elevated blood pressure in DOCA/salt-treated mice. Hence, our findings highlight CCR2 as a promising therapeutic target to reduce both macrophage accumulation in the vascular wall and blood pressure in hypertension.

Measuring and analyzing color and texture information in anatomical leaf cross sections: An approach using computer vision to aid plant species identification

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A ring system detected around the Centaur (10199) Chariklo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Bacterial leaf glands in Styrax camporum (Styracaceae): first report for the family

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leaf colleters in Tabernaemontana catharinensis (Apocynaceae, Rauvolfioideae): structure, ontogenesis, and cellular secretion

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Glandular trichome diversity on leaves of Lippia origanoides and Lippia stachyoides (Verbenaceae): morphology, histochemistry, and ultrastructure

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Gynoecial ontogeny of Anthurium: contributions for floral developmental studies in Araceae (Alismatales)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Paricipation in Bauru marter plans, Brazil: analysis of the historical evolution of the consultation process

In Brazil, a policy on citizen participation and consultation in urban intervention programs, in particular in the development of master plans, was first introduced into the Federal Constitution in 1988. This article presents an historical reconstitution of Master Plans in Bauru – State of São Paulo – Brazil. The 1968, 1988 and 2005/2006 consultation methods are analyzed using established criteria. The degree of community participation in the processes is estimated by drawing on a typology based on the level of involvement by residents. The effects of participation caused by changes in political regime, technical planning vision, legal support to consultation, recognition of community importance and knowledge acquired during the process are highlighted and discussed.

Subtitling as a pedagogical tool for language teaching in journalism

This study was designed to present and discuss some results produced by a research involving the use of English subtitles of some news videos from the webiste Reuters.com (http://www.reuters.com) with pedagogical reasons in a Brazilian context (Academic English for Journalism). We have developed the research during two semesters at UNESP (Universidade Estadual Paulista Júlio de Mesquita Filho). The professor in charge of the study has chosen the students of Journalism as the audience to whom the videos were presented. The assumptions of many theorists and experts in Audiovisual Translation were adopted as our Theoretical Sources. The first step of the study was the assessment of the syllabus of each course. This was very helpful as a guidance in order to choose the most relevant and interesting videos for students. After the evaluation of academic and professional interests, we chose some videos to insert appropriate subtitles, according to some strategies suggested by Panayota Georgakopoulou and Henrik Gottlieb. Finally we presented the videos during the English classes. At the first time, they were presented without subtitles just to notice the comprehension level of the students. After that, the videos were presented with English subtitles. As we first assumed, the students haven’t had the whole comprehension of specific details during the first presentation, they have just used their previous knowledge and the visual aids to help them in a superficial understanding of the news. As the subtitles appear, the process of communication was finally accomplished.