A permanência de Tlaxcala frente ao poderio mexica nos séculos XV e XVI

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A incorporação dos negros no mercado de trabalho: um estudo de 1930 a 1945

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Negro suspeito, negro bandido: um estudo sobre o discurso policial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A potência das imagens em uma miscelânea amazônica: sociabilidade e estilo de vida nos Pássaros Juninos de Belém-Pará

Os Pássaros Juninos ou Pássaros Melodrama-Fantasia representam um tipo de teatro musicado próprio do Pará. Eles possuem como referenciais elementos de diversos gêneros teatrais e de manifestações regionais, trazendo à tona fontes das culturas negra, branca e indígena, que desde a colonização da região se miscigenaram, resultando naquilo que hoje entendemos por “cultura amazônica”. Este trabalho pretende discutir o caráter mestiço que engendrou as circunstâncias do surgimento dos Pássaros Juninos e, por conseguinte, explicitar que tal manifestação evoca distintas imagens que convergem na construção de narrativas amazônicas fantásticas expressas sob a forma de sociabilidades singulares ao contexto paraense.

Raça e educação na América Latina: um estudo comparado do pensamento de José Veríssimo (Brasil/1857-1916) e José Ingenieros (Argentina/1877-1925)

O presente estudo teve como objeto de pesquisa o pensamento de José Veríssimo (Brasil) e José Ingenieros (Argentina) sobre raça e educação. Trata-se de uma proposta circunscrita num estudo comparado deste pensamento entre esses dois intelectuais. Problematizou-se como questão central: de que forma o pensamento de José Veríssimo e José Ingenieros articula a relação entre raça e educação na América Latina do final século XIX e início do século XX? Como objetivo geral, desejou-se analisar, por meio de um estudo comparado, o pensamento de José Veríssimo e de José Ingenieros sobre educação, dando destaque às interações destes com o conceito de raça na América Latina do século XIX. Como objetivos específicos, pretende-se: 1) destacar o contexto histórico do pensamento educacional de José Veríssimo e José Ingenieros; 2) identificar nas obras destes autores as relações entre raça e educação, assim como correlacionar o pensamento de José Veríssimo e de José Ingenieros sobre raça e educação com a história do pensamento intelectual latino-americano. Metodologicamente, inscreve-se o estudo no campo da História Intelectual e da História Cultural. O corpus da pesquisa está composto de duas obras de cada autor. De José Veríssimo, trabalhou-se com As Populações indígenas e mestiças da Amazônia: sua linguagem, suas crenças e seus costumes (1887) e Educação nacional (1906). De José Ingenieros, cotejou-se El hombre medíocre (1913) e Las fuerças morales (obra póstuma). Os resultados do estudo indicam que o modo como as teorias da raça chegam a América Latina são fundamentais para a compreensão do pensamneto dos autores. Nesse sentido, foi preciso realizar uma breve reflexão sobre as discussões teóricas que o tema raça suscitou na América Latina do século XIX, já que tanto José Veríssimo quanto José Ingenieiros nasceram e viveram parte de suas vidas nesse período. O primeiro nasceu no extremo norte do Brasil, no Estado do Pará, e viveu entre 1857 e 1916. Dedicou-se ao estudo da Crítica Literária e refletiu sobre a educação, colocando-a como instrumental necessário para a elevação da população mestiça do país à condição de civilizada. O segundo nasceu em Palermo, na Itália, mas migrou para a Argentina ainda criança, tornando-se cidadão argentino. Dedicou-se ao estudo da Psiquiatria, mas enveredouse, em particular, pela área da Antropologia Criminológica. Ao discutir as perturbações mentais dos indivíduos na sociedade argentina, José Ingenieros se reporta à colonização e às condições materiais dos sujeitos. Para ele, no final do século XIX as raças inferiores continuavam a representar um entrave para o desenvolvimento da Argentina. À princípio, identifica-se que o homem medíocre de Ingenieiros muito se assemelha ao homem indolente de Veríssimo. Ambos os estados – medíocre e indolente – representavam, para estes intelectuais, um estado atrasado que não se via mais presente no homem civilizado. Desse modo, defendem condições externas objetivas diferentes para que, tanto na Argentina quanto no Brasil, as mudanças internas determinadas pela raça, que resultaram no homem medíocre e indolente, fossem superadas. Dentre essas condições externas, a educação desponta como elemento necessário para a superação da indolência e da mediocridade.

As crônicas do Inca Garcilaso de La Vega: um discurso de legitimação

A literatura latino-americana está marcada pela heterogeneidade existente na América Latina, e a crônica é considerada o início desta heterogeneidade, devido ao fato de narrar um mundo desconhecido a leitores que fazem parte de outra realidade, gerando assim, uma situação de conflito. Os relatos escritos das civilizações andinas, em sua maioria, são de cronistas espanhóis, no entanto, também nos deparamos com alguns cronistas “índios” e mestiços, como o Inca Garcilaso de la Vega. Ele se destaca não somente por representar esta pequena parcela, ou seja, por ser um mestiço, mas, principalmente por ser herdeiro de duas nobrezas: a nobreza espanhola e a nobreza incaica. O cronista Inca Garcilaso era filho do capitão espanhol Garcilaso de la Vega, que possuía uma família que se destacava na guerra e na literatura; e de Chimpu Ocllo, uma princesa Inca, neta do Imperador Túpac Inca Yupanqui. Porém, este privilégio em relação aos outros mestiços, não lhe garantia o reconhecimento como nobre diante da coroa espanhola. Por isso, veremos neste trabalho que um dos seus intuitos ao escrever as crônicas Comentarios Reales de los Incas e Historia General del Perú, era o de tentar legitimar o seu status social diante dos espanhóis por meio de relatos que descrevem todos os feitos e avanços dos Incas, bem como afirmar, como uma de suas justificativas, que a colonização foi aceita pelos indígenas e estes estavam aptos à catequização, sendo uma maneira do Rei da Espanha e a Igreja Católica “salvarem” este povo da barbárie. Desta maneira, o Inca Garcilaso cria um discurso contraditório, pois, ao mesmo tempo que defende os espanhóis, ele glorifica o Império Inca

América latina: as coisas para além delas mesmas

If Plato compared the artist's work a reflection of the things, the contemporary art transcends the projection of things beyond themselves by creating unusual pictures, requiring the reader a posture of meanings' digger to establish the signification. Our object is the mestizo, hybrid and heterogeneous Latin America presented by sensitive eyes of art. We chose the route of ambiguous and poetic language of art, selected three works of Brazilian artist Regina Silveira since the last two decades has sought to un/construction of the image from the shadow, reflection, anamorphic projections, which offers unusual images, poetic visual paradoxes. Art as a mirror labyrinth where the reader/viewer as a wanderer without contemporary "gps" to select territories where will step from a map that he will have to build.

Early Rheumatoid Arthritis in Latin America: Low Socioeconomic Status Related to High Disease Activity at Baseline

Objective. To determine the influence of socioeconomic factors on disease activity in a Latin American (LA) early rheumatoid arthritis (RA) multinational inception cohort at baseline. Methods. Clinical evaluation, ethnicity, socioeconomic status (SES), 4-variable Disease Activity Score in 28 joints using the erythrocyte sedimentation rate (DAS28-ESR), Health Assessment Questionnaire (HAQ) disability index (DI), and erosions were recorded in 1,093 patients with early RA (<1 year from onset). Multivariate analyses evaluated influences of sex, age, marital status, education, medical coverage, SES, and ethnicity on HAQ DI, DAS28-ESR, and presence of erosions. Results. Ethnicities included 43% Mestizo, 31% Caucasian, 19% African LA, 4% Amerindian, and 3% other. Fifty-eight percent were of low/low-middle SES, 42% had <8 years of education, 21% had no medical coverage, median disease duration was 6 months (25th, 75th percentiles 4, 9 months), median HAQ DI score was 1.25 (25th, 75th percentiles 0.63, 2.00), median DAS28-ESR score was 6.2 (25th, 75th percentiles 4.9, 7.2), and 25% had erosions. Women and Mestizos, African LA, and Amerindians had earlier onset than men or Caucasians (P < 0.01). When adjusted by country, the analysis of covariance model showed that low/low-middle SES, female sex, partial coverage, and older age were associated with worse HAQ DI scores; only low/low-middle SES was associated with higher DAS28 scores. Statistically significant differences were found in HAQ DI and DAS28 scores between countries. When excluding country, low/low-middle SES, female sex, and no coverage were associated with worse HAQ DI and DAS28 scores, whereas separated/divorced/widowed status was associated with worse HAQ DI scores and age was associated with worse DAS28 scores. Logistic regression showed that older age, no coverage, and the Amerindian and other ethnic groups were associated with erosions. Conclusion. We compared early RA patients from the main LA ethnic groups. Our findings suggest that low/low-middle SES is important in determining disease activity. A more genetic-related background for erosions is possible.

Comparison of the Clinical Expression of Patients with Ankylosing Spondylitis from Europe and Latin America

Objective. To compare the clinical, demographic, and serologic characteristics and the treatment of patients diagnosed with ankylosing spondylitis (AS) from Europe (EU) and Latin America (LA). Methods. We included 3439 patients from national registries: the Spanish Registry of Spondyloarthritis (REGISPONSER), the Belgian registry (ASPECT), and the Latin American Registry of Spondyloarthropathies (RESPONDIA). We selected patients with diagnosis of AS who met the modified New York classification criteria. Demographic, clinical, disease activity, functional, and metrological measurement data were recorded. Current treatment was recorded. The population was classified into 2 groups: patients with disease duration < 10 years and those with disease duration >= 10 years. A descriptive and comparative analysis of variables of both groups was carried out. Results. There were 2356 patients in EU group and 1083 in LA group. Prevalence of HLA-B27 was 71% in LA group and 83% in EU group (p < 0.001). We found a greater frequency of peripheral arthritis and enthesitis (p < 0.001) in the LA population; prevalence of arthritis was 57% in LA and 42% in EU, and for enthesitis, 54% and 38%. Except for treatment with anti-tumor necrosis factor (anti-TNF), the use of nonsteroidal antiinflammatory drugs (NSAID), corticosteroids, and disease-modifying antirheumatic drugs (DMARD), and the association of anti-TNF and methotrexate use showed a significant difference (p < 0.001) in the 2 populations. Conclusion. The principal differences in the clinical manifestations of patients with AS from EU and LA were the greater frequency of peripheral arthritis and enthesitis in LA group, the higher percentage of HLA-B27 in EU group, and the form of treatment, with a greater use of NSAID, steroids, and DMARD in the LA group. (First Release Nov 15 2012; J Rheumatol 2012;39:2315-20; doi:10.3899/jrheum.110687)

Multiple trichoblastomas in a dog

Background – Hair follicle tumours generally present as benign, solitary masses and have a good prognosis following surgical resection. Hypothesis/Objectives – This report describes a case of multiple trichoblastomas in a dog. Animal – A 2-year-old crossbred dog presented with multiple soft cutaneous periocular, perilabial, submandibular and nasal nodules, between 2 and 9 cm in diameter, located on the right side of the face. New nodules were observed on the same side of the face at a second consultation 3 weeks later. Methods – Surgical resection of all nodules was performed in two procedures. Three nodules were initially resected and submitted for histolopathology and immunohistochemistry. The diagnosis was trichoblastoma for all three. At the time of the second consultation, new and remaining nodules were biopsied and the diagnosis of trichoblastoma confirmed. The dog was treated with doxorubicin and piroxicam for 30 days prior to the second surgical procedure in an attempt to reduce new tumour growth and the size of present tumours. All nodules were resected and the defects closed using rotation flaps. Results – No recurrence of the neoplasm was noted within 10 months after surgery. Conclusions and clinical importance – Trichoblastomas are generally benign but can present as multiple neoplasms that may require surgical resection and may respond to chemotherapy. To the authors’ knowledge, this is the first report of multiple trichoblastomas in a dog.

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

A recent genome-wide study revealed an association between variation in the PNPLA3 gene and liver fat content. In addition, the PNPLA3 single-nucleotide polymorphism rs738409 (M148I) was reported to be associated with advanced alcoholic liver disease in alcohol-dependent individuals of Mestizo descent. We therefore evaluated the impact of rs738409 on the manifestation of alcoholic liver disease in two independent German cohorts. Genotype and allele frequencies of rs738409 (M148I) were determined in 1,043 alcoholic patients with or without alcoholic liver injury and in 376 at-risk drinkers from a population-based cohort. Relative to alcoholic patients without liver damage (n = 439), rs738409 genotype GG was strongly overrepresented in patients with alcoholic liver cirrhosis (n = 210; OR 2.79; P(genotype) = 1.2 × 10(-5) ; P(allelic) = 1.6 × 10(-6) ) and in alcoholic patients without cirrhosis but with elevated alanine aminotransferase levels (n = 219; OR 2.33; P(genotype) = 0.0085; P(allelic) = 0.0042). The latter, biochemically defined association was confirmed in an independent population-based cohort of at-risk drinkers with a median alcohol intake of 300 g/week (OR 4.75; P(genotype) = 0.040; P(allelic) = 0.022), and for aspartate aminotransferase (AST) levels. Frequencies of allele PNPLA3 rs738409(G) in individuals with steatosis and normal alanine aminotransferase (ALT) and AST levels were lower than in alcoholics without steatosis and normal ALT/AST (P(combined) = 0.03). The population attributable risk of cirrhosis in alcoholic carriers of allele PNPLA3 rs738409(G) was estimated at 26.6%. CONCLUSION: Genotype PNPLA3 rs738409(GG) is associated with alcoholic liver cirrhosis and elevated aminotransferase levels in alcoholic Caucasians.

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome.

BACKGROUND Congenital long-QT syndrome (LQTS) is potentially lethal secondary to malignant ventricular arrhythmias and is caused predominantly by mutations in genes that encode cardiac ion channels. Nearly 25% of patients remain without a genetic diagnosis, and genes that encode cardiac channel regulatory proteins represent attractive candidates. Voltage-gated sodium channels have a pore-forming alpha-subunit associated with 1 or more auxiliary beta-subunits. Four different beta-subunits have been described. All are detectable in cardiac tissue, but none have yet been linked to any heritable arrhythmia syndrome. METHODS AND RESULTS We present a case of a 21-month-old Mexican-mestizo female with intermittent 2:1 atrioventricular block and a corrected QT interval of 712 ms. Comprehensive open reading frame/splice mutational analysis of the 9 established LQTS-susceptibility genes proved negative, and complete mutational analysis of the 4 Na(vbeta)-subunits revealed a L179F (C535T) missense mutation in SCN4B that cosegregated properly throughout a 3-generation pedigree and was absent in 800 reference alleles. After this discovery, SCN4B was analyzed in 262 genotype-negative LQTS patients (96% white), but no further mutations were found. L179F was engineered by site-directed mutagenesis and heterologously expressed in HEK293 cells that contained the stably expressed SCN5A-encoded sodium channel alpha-subunit (hNa(V)1.5). Compared with the wild-type, L179F-beta4 caused an 8-fold (compared with SCN5A alone) and 3-fold (compared with SCN5A + WT-beta4) increase in late sodium current consistent with the molecular/electrophysiological phenotype previously shown for LQTS-associated mutations. CONCLUSIONS We provide the seminal report of SCN4B-encoded Na(vbeta)4 as a novel LQT3-susceptibility gene.

First thoughts on surface tonal patterns in Amawaka, a Panoan language of Peru and Brazil

Amawaka ([ɑmɨ̃ˈwɐkɑ]) is a highly endangered and underdocumented tonal language of the Headwaters (Fleck 2011) subgroup of the Panoan family in the Southwest Amazon Basin, spoken by approximately 200 people. Undocumented phonetic and phonological phenomena of Amawaka include its tonal structure, both in terms of surface realizations and the patterns underlying these realizations. Original audiovisual data from the author’s fieldwork in various Amawaka communities at the Peru-Brazil border will illuminate the as-yet obscure tonal systematicity of the language. Unlike other elements, monosyllabic bimoraic phonological nominal words with long vowels display variation in their surface realization. All the words with the open back unrounded /ɑ/, like /ˈkɑ̀:/ (patarashca, a traditional Amazonian dish), /ˈnɑ̀:/ “mestizo” etc. [with the exception of /ˈtɑ:/ “reed”, which surfaces with either a H or L tone] bear a low tone in isolation. This realization contrasts with all the encountered nominal monosyllables with vowels from the close and close-mid front and central spectrum /i, ɘ, ɨ, ɨ̃/, which clearly surface as high tone words in isolation, for example /ˈmɨ̃́:/ (a clay-lick for animals), /ˈwí:/ “Anopheles, spp. mosquito”. Monosyllables with close-mid back rounded /o/ have a less restrictive pitch that varies among speakers from low to high realizations, and sometimes even across the speech tokens from an individual speaker, e.g. /wó:/ or /wō:/ “hair”, /ɧō:/ or /ɧò:/ (a type of tarantula). Phrasal tonal phonology is more complex, when these three kinds of monosyllables appear in larger noun phrases. Some retain the same surface tones as their isolation form, while others seem to vary freely in their surface realization, e.g. /ˈtɘ́:.nɑ̀:/ or /ˈtɘ́:.nɑ́:/ ‘one mestizo’. Yet other monosyllables, e.g. /mɑ̀:/, exhibit a falling tone when preceded by a H syllable, suggesting probably latent tone sandhi phenomena, e.g /ˈtɘ́:.mɑ̂:/ (one clay-lick for parrots). In disyllabic, trisyllabic and quadrisyllabic nouns, tonal and stress patterns generally seem to be more consistent and tend to be retained both in isolation and in larger intonational phrases. Disyllabic nouns, for instance, surface as L-H or L-L when a glottal stop is in coda position. The association of L with a glottal stop is a feature that occurs in other Panoan languages as well, like Capanahua (Loos 1969), and more generally it is an areal feature, found in other parts of Amazonia (Hyman 2010). So, tone has significant interactions with the glottal stop and glottalization, which generally co-occurs with L. The data above suggest that the underlying tonal system of Amawaka is much more complex than the privative one-tone analysis (/H/ vs. Ø, i.e. lack of tone) that was proposed by Russell and Russell (1959). Evidence from field data suggests either an equipollent (Hyman 2010) two-tone opposition between /H/ and /L/, or a hybrid system, with both equipollent and privative features; that is, /H/ vs. /L/ vs. either Ø or /M/. This first systematic description of Amawaka tone, in conjunction with ongoing research, is poised to address broader questions concerning interrelationships between surface/underlying tone and other suprasegmental features, such as nasality, metrical stress, and intonation. References Fleck, David W. 2011. Panoan languages and linguistics. In Javier Ruedas and David W. Fleck (Eds.), Panoan Histories and Interethnic Identities, To appear. Hyman, Larry. 2010. Amazonia and the typology of tone systems. Presented at the conference Amazonicas III: The structure of the Amazonian languages. Bogotá. Loos, Eugene E. 1969. The phonology of Capanahua and its grammatical basis. Norman: SIL and U. Oklahoma. Russell, Robert & Dolores. 1959. Syntactotonemics in Amahuaca (Pano). Série Lingüistica Especial, 128-167. Publicaçoes do Museu Nacional, Rio de Janeiro, Brasil.

Towards an analysis of tonal patterns in Amawaka, a Panoan language of Peru and Brazil

Amawaka ([ɑmɨ̃ˈwɐkɑ]) is a highly endangered and underdocumented tonal language of the Headwaters (Fleck 2011) subgroup of the Panoan family in the Southwest Amazon Basin, spoken by approximately 200 people. Undocumented phonetic and phonological phenomena of Amawaka include its tonal structure, both in terms of surface realizations and the patterns underlying these realizations. Original audiovisual data from the author’s fieldwork in various Amawaka communities at the Peru-Brazil border will illuminate the as-yet obscure tonal systematicity of the language. Unlike other elements, monosyllabic bimoraic phonological nominal words with long vowels display variation in their surface realization. All the words with the open back unrounded /ɑ/, like /ˈkɑ̀:/ (a traditional Amazonian dish), /ˈnɑ̀:/ “mestizo” etc. [with the exception of /ˈtɑ:/ “reed”, which surfaces with either a H or L tone] bear a low tone in isolation. This realization contrasts with all the encountered nominal monosyllables with vowels from the close and close-mid front and central spectrum /i, ɘ, ɨ, ɨ̃/, which clearly surface as high tone words in isolation, for example /ˈmɨ̃́:/ (a clay-lick for animals), /ˈwí:/ “Anopheles, spp. mosquito”. Monosyllables with close-mid back rounded /o/ have a less restrictive pitch that varies among speakers from low to high realizations, and sometimes even across the speech tokens from an individual speaker, e.g. /wó:/ or /wō:/ “hair”, /ɧō:/ or /ɧò:/ (a type of tarantula). Phrasal tonal phonology is more complex, when these three kinds of monosyllables appear in larger noun phrases. Some retain the same surface tones as their isolation form, while others seem to vary freely in their surface realization, e.g. /ˈtɘ́:.nɑ̀:/ or /ˈtɘ́:.nɑ́:/ ‘one mestizo’. Yet other monosyllables, e.g. /mɑ̀:/, exhibit a falling tone when preceded by a H syllable, suggesting probably latent tone sandhi phenomena, e.g /ˈtɘ́:.mɑ̂:/ (one clay-lick for parrots). In disyllabic, trisyllabic and quadrisyllabic nouns, tonal and stress patterns generally seem to be more consistent and tend to be retained both in isolation and in larger intonational phrases. Disyllabic nouns, for instance, surface as L-H or L-L when a glottal stop is in coda position. The association of L with a glottal stop is a feature that occurs in other Panoan languages as well, like Capanahua (Loos 1969), and more generally it is an areal feature, found in other parts of Amazonia (Hyman 2010). So, tone has significant interactions with the glottal stop and glottalization, which generally co-occurs with L. The data above suggest that the underlying tonal system of Amawaka is much more complex than the privative one-tone analysis (/H/ vs. Ø, i.e. lack of tone) that was proposed by Russell and Russell (1959). Evidence from field data suggests either an equipollent (Hyman 2010) two-tone opposition between /H/ and /L/, or a hybrid system, with both equipollent and privative features; that is, /H/ vs. /L/ vs. either Ø or /M/. This first systematic description of Amawaka tone, in conjunction with ongoing research, is poised to address broader questions concerning interrelationships between surface/underlying tone and other suprasegmental features, such as nasality, metrical stress, and intonation. References Fleck, David W. 2011. Panoan languages and linguistics. In Javier Ruedas and David W. Fleck (Eds.), Panoan Histories and Interethnic Identities, To appear. Hyman, Larry. 2010. Amazonia and the typology of tone systems. Presented at the conference Amazonicas III: The structure of the Amazonian languages. Bogotá. Loos, Eugene E. 1969. The phonology of Capanahua and its grammatical basis. Norman: SIL and U. Oklahoma. Russell, Robert & Dolores. 1959. Syntactotonemics in Amahuaca (Pano). Série Lingüistica Especial, 128-167. Publicaçoes do Museu Nacional, Rio de Janeiro, Brasil.

Inconfidencia (el Aleijadinho) de Abelardo Arias y correspondencia arte-religiosidad

En el año 1979, Abelardo Arias publica su segunda novela de base histórica titulada Inconfidencia (El Aleijadinho), la cual recrea el Brasil imperial de fines del siglo XVIII, ámbito que dio a luz a ese extraño genio de la plástica que fue el mestizo Antonio Francisco de Lisboa, "el Aleijadihno ". Arias elude la facilidad de la biografia novelada y logra acercarse al escultor leproso desde su propia tensión de artista. Comprende, por ello, su tortuosa vida de marginado y hombre desengañado del amor, que vuelca su existencia a la creación estética. La relación que el Aleijadihno tiene con su obra, oscilante entre la exaltación religiosa y la pasión amorosa, nos lleva a estudiar en profundidad las líneas de tensión en torno de la correspondencia entre arte mayor y religiosidad. Como señala Abel Posse al respecto: "El gran artista (el Aleijadihno) tiende a fundar su obra alrededor de un weltanschaung o cosmovisión total y esta ambición lo acerca al mundo religioso y a la especulación metafisica ". La obra, por lo tanto, desarrolla una silenciosa agonia existencial y religiosa, el combate callado de un "alejado ", de un condenado a muerte.