974 resultados para Macro releases
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This report presents recidivism data on offenders released from Iowa prisons during State FY1996 (July 1, 1995 – June 30, 1996).
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The peptidoglycan of Gram-positive bacteria is known to trigger cytokine release from peripheral blood mononuclear cells (PBMCs). However, it requires 100-1000 times more Gram-positive peptidoglycan than Gram-negative lipopolysaccharide to release the same amounts of cytokines from target cells. Thus, either peptidoglycan is poorly active or only part of it is required for PBMC activation. To test this hypothesis, purified Streptococcus pneumoniae walls were digested with their major autolysin N-acetylmuramoyl-L-alanine amidase, and/or muramidase. Solubilized walls were separated by reverse phase high pressure chromatography. Individual fractions were tested for their PBMC-stimulating activity, and their composition was determined. Soluble components had a Mr between 600 and 1500. These primarily comprised stem peptides cross-linked to various extents. Simple stem peptides (Mr <750) were 10-fold less active than undigested peptidoglycan. In contrast, tripeptides (Mr >1000) were >/=100-fold more potent than the native material. One dipeptide (inactive) and two tripeptides (active) were confirmed by post-source decay analysis. Complex branched peptides represented </=2% of the total material, but their activity (w/w) was almost equal to that of LPS. This is the first observation suggesting that peptidoglycan stem peptides carry high tumor necrosis factor-stimulating activity. These types of structures are conserved among Gram-positive bacteria and will provide new material to help elucidate the mechanism of peptidoglycan-induced inflammation.
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This paper examines two principal categories of manipulative behaviour. The term'macro-manipulation' is used to describe the lobbying of regulators to persuadethem to produce regulation that is more favourable to the interests of preparers.'Micro-manipulation' describes the management of accounting figures to produce abiased view at the entity level. Both categories of manipulation can be viewed asattempts at creativity by financial statement preparers. The paper analyses twocases of manipulation which are considered in an ethical context. The paperconcludes that the manipulations described in it can be regarded as morallyreprehensible. They are not fair to users, they involve an unjust exercise ofpower, and they tend to weaken the authority of accounting regulators.
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This paper evaluates new evidence on price setting practices and inflation persistence in the euro area with respect to its implications for macro modelling. It argues that several of the most commonly used assumptions in micro-founded macro models are seriously challenged by the new findings.
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Entre 1978 y 1987 se realizaron muestreos de la macrofauna bentónica en 10 localidades del litoral y 14 estaciones del sublitoral, en el área de Pisco, Perú. Se diferenciaron ocho biotopos, en los que se hallaron un total de 330 taxones (excluyendo Nematoda), de los cuales 305 fueron determinados por los menos hasta el nivel genérico. El total de taxa está agrupado en 145 familias, 43 órdenes y 15 phyla, e incluye 112 Mollusca, 104 Annelida, 75 Crustacea y 39 taxa pertenecientes a otros grupos taxonómicos. Exclusivamente en fondos y orillas rocasas se encontraron 158 taxa. Considerando solamente los moluscos, poliquetos y crustáceos, con el presente estudio se incrementa de 103 a 289 el número de taxa registradas para el área investigada.
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Nas paisagens do norte do estado de São Paulo, sob domínio do Planalto Ocidental, ferricretes ocorrem em diferentes níveis topográficos e, apesar de pouco documentados, constituem feições que se repetem com freqüência sobre os arenitos cretácicos do Grupo Bauru, Formação Adamantina. Realizou-se um estudo morfológico, em diferentes escalas de observação, a fim de elucidar a gênese desses ferricretes (plintita e petroplintita) encontrados no terço inferior de uma vertente dominada por solos com B textural. A área estudada localiza-se na Estação Experimental de Agronomia de Pindorama, do Instituto Agronômico de Campinas (IAC), região norte do estado de São Paulo. Dois perfis foram selecionados para a descrição morfológica detalhada e para as observações micromorfológicas com lupa binocular e microscópio petrográfico. As evidências macro e micromorfológicas dos ferricretes revelam uma origem associada à lixiviação do ferro ferroso a montante da paisagem e reprecipitação na zona de vadosa. Esses ferricretes apresentaram diferentes fábricas internas, a maioria dos quais com estruturas de degradação, evidenciando o desmantelamento atual da couraça. As diferenças nas fábricas internas estão relacionadas com a distribuição do esqueleto e do plasma: alguns apresentam esqueleto bem selecionado, com predominância de areia muito fina, enquanto em outros predomina a areia média; outros, ainda, mostram esqueleto pouco selecionado, assemelhando-se ao fundo matricial interglebular; a maioria mostra alguns volumes ocupados apenas por plasma. Demonstra-se que fatores pedo-lito-biológicos estão envolvidos nessa diversidade entre ferricretes de um mesmo horizonte, formando in situ glébulas tão distintas em suas fábricas, que podem ser erroneamente interpretadas como provenientes de diferentes locais da paisagem, transportadas e depositadas nas baixas encostas durante a gênese dos ferricretes.
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Achieving a high degree of dependability in complex macro-systems is challenging. Because of the large number of components and numerous independent teams involved, an overview of the global system performance is usually lacking to support both design and operation adequately. A functional failure mode, effects and criticality analysis (FMECA) approach is proposed to address the dependability optimisation of large and complex systems. The basic inductive model FMECA has been enriched to include considerations such as operational procedures, alarm systems. environmental and human factors, as well as operation in degraded mode. Its implementation on a commercial software tool allows an active linking between the functional layers of the system and facilitates data processing and retrieval, which enables to contribute actively to the system optimisation. The proposed methodology has been applied to optimise dependability in a railway signalling system. Signalling systems are typical example of large complex systems made of multiple hierarchical layers. The proposed approach appears appropriate to assess the global risk- and availability-level of the system as well as to identify its vulnerabilities. This enriched-FMECA approach enables to overcome some of the limitations and pitfalls previously reported with classical FMECA approaches.
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RESUMO Neossolos Regolíticos no Agreste Meridional de Pernambuco são utilizados para diversas atividades agrícolas, com destaque para a produção de feijão. Há uma variação expressiva na produção dessa cultura, possivelmente associada à presença de lamelas, que conferem comportamento hídrico distinto entre esses solos. Objetivou-se analisar as características macromorfológicas, micromorfológicas e físicas de Neossolos Regolíticos localizados no Agreste Meridional de Pernambuco, com a finalidade de se entender o comportamento hídrico desses solos. Foram coletados e analisados dois perfis de solos localizados nos municípios de Paranatama (P1 - sem lamela) e de São João (P2 - com lamela). Os resultados mostraram que nos atributos morfológicos (cor, textura, estrutura e consistência) não foram observadas diferenças expressivas entre os dois perfis de solos; os atributos físicos (teor de argila, macroporosidade, microporosidade, capacidade de campo e ponto de murcha permanente) apresentaram diferença significativa entre os horizontes dos perfis estudados; a micromorfologia indicou que a maior retenção de água no P2 é consequência da presença de zonas com empacotamento mais denso de seus componentes (empacotamento aglomerático) e expressividade das pontes de argila; e sugere-se adoção do termo “lamélico” pelo atual Sistema Brasileiro de Classificação de Solos (em 4º nível categórico) para diferenciação dos perfis estudados.
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Neste ensaio procuro desenvolver uma argumentação a favor da superação dos monismos metodológicos no campo da pesquisa em sociologia da educação. Com base no que Jeffrey Alexander (1987) denominou o "novo movimento teórico", defendo a necessidade de superar a divisão do trabalho de pesquisa entre os investigadores que se dedicam à microssociologia e os que preferem abordagens macrossociais. Nessa perspectiva, as opções teórico-metodológicas devem-se ancorar nas necessidades da investigação e não numa opção a priori do pesquisador por qualquer uma das alternativas.
Nonfunctioning Pituitary Macro Incidentalomas Benefit from Early Surgery before Becoming Symptomatic
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Este artigo analisa as relações macro/micro em teses e dissertações sobre currículo da educação básica, produzidas em programas brasileiros de pós-graduação em educação da Região Sudeste, no período de 1996 a 2002.
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River regulation for the purposes of public water supply causes the flow regime downstream of a dam to change. Traditionally, in the UK, such regulation was accompanied by requirements for reservoir releases to compensate downstream water users (e.g. industry) for the loss of natural flow (compensation flows). In this article, we compare a unique pre-impoundment macroinvertebrate data set for a regulated upland river with survey data post-impoundment. This allows a longitudinal assessment of the response of the system to regulation. The Derwent River, Northumberland, was impounded in 1966. Impacts on the hydrological regime were quantified by comparing long-term hydrographs, flow duration curves, flow ranges and flashiness indices for the pre-impoundment and post-impoundment periods. The comparison of changes in macroinvertebrate richness and diversity post-impoundment showed that the change in flow regime has had limited effect on the ecological community structure. The flow regime of the Derwent River has become less flashy with fewer extreme events, and the richness and the diversity of macroinvertebrates have, in some cases, increased and at worst have not deteriorated. We suggest that this reflects the strict compensation regime, which has guaranteed minimum flows at all times. Copyright (c) 2012 John Wiley & Sons, Ltd.
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Expanding on research first presented in the Iowa Board of Parole FY99 Annual Report, this report presents recidivism data on offenders released from Iowa prisons during State FY1996 (July 1, 1995 – June 30, 1996). The figures presented here differ from those included in last year’s report due to four changes in the study. First, this year’s research includes data on those released from work release facilities, who were inadvertently omitted last year. In addition, the current figures include an additional year of tracking, as a second round of “rapsheets” was obtained to detect recidivism occurring within the last year.2 Also enhancing this year’s report is the availability of national recidivism data through the Interstate Identification Index (III). Further, while last year’s data looked only at the first new offense following release, this year’s study examines the most serious new conviction, resulting in higher felony recidivism rates. One note of caution should be voiced concerning the use of out-of-state records. A review of these records suggests very incomplete disposition reporting in III from some other states. In examining these records, it was not unusual to find a string of serious arrests with no dispositions noted. It was tempting in these situations to conclude that there must have been a conviction at some point, but we have resisted that urge when presenting figures on new convictions. This report is not intended to be an all-encompassing review of recidivism. Rather, it is meant to provide an illustration of the types of recidivism data available on prison releases in Iowa. Readers interested in other analyses of the data are urged to contact CJJP with suggestions and requests.
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There is a debate on whether an influence of biotic interactions on species distributions can be reflected at macro-scale levels. Whereas the influence of biotic interactions on spatial arrangements is beginning to be studied at local scales, similar studies at macro-scale levels are scarce. There is no example disentangling, from other similarities with related species, the influence of predator-prey interactions on species distributions at macro-scale levels. In this study we aimed to disentangle predator-prey interactions from species distribution data following an experimental approach including a factorial design. As a case of study we selected the short-toed eagle because of its known specialization on certain prey reptiles. We used presence-absence data at a 100 Km2 spatial resolution to extract the explanatory capacity of different environmental predictors (five abiotic and two biotic predictors) on the short-toed eagle species distribution in Peninsular Spain. Abiotic predictors were relevant climatic and topographic variables, and relevant biotic predictors were prey richness and forest density. In addition to the short-toed eagle, we also obtained the predictor's explanatory capacities for i) species of the same family Accipitridae (as a reference), ii) for other birds of different families (as controls) and iii) species with randomly selected presences (as null models). We run 650 models to test for similarities of the short-toed eagle, controls and null models with reference species, assessed by regressions of explanatory capacities. We found higher similarities between the short-toed eagle and other species of the family Accipitridae than for the other two groups. Once corrected by the family effect, our analyses revealed a signal of predator-prey interaction embedded in species distribution data. This result was corroborated with additional analyses testing for differences in the concordance between the distributions of different bird categories and the distributions of either prey or non-prey species of the short-toed eagle. Our analyses were useful to disentangle a signal of predator-prey interactions from species distribution data at a macro-scale. This study highlights the importance of disentangling specific features from the variation shared with a given taxonomic level.