113 resultados para Jacoby, JuliusJacoby, JuliusJuliusJacoby
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Daniel Jacoby
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Jacoby
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Johann Jacoby
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1 Brief an Ernst Jacob von Max Horkheimer; 31 Briefe zwischen Stefan Jacobwicz und Max Horkheimer, 1936-1945; 1 Brief an die American Consul Lisabon von Max Horkheimer; 23 Briefe zwischen Heinz Jacoby, Lilli Jacoby und Max Horkheimer, 1936-1943; 1 Brief von Max Horkheimer an John B. Norman, 29.06.1942; 1 Brief von Max Horkheimer an George L. Warren; 1 Brief vom Service Social d'Aide aux Emigrants Paris an Heinz Jacobi, 18.01.1940; 1 Brief von Max Horkheimer an Jaeger , 29.09.1937; 5 Brief zwischen Philip C. Jessup und Max Horkheimer, 15.10.1940-1941; 3 Briefe an die Jewish National and University Library Jerusalem von Max Horkheimer, 1943, 1949; 5 Briefe zwischen der Jewish Telegraphic Agency New York und Max Horkheimer, 1940; 2 Briefe zwischen Ernest Jones und Max Horkheimer, 29.04.1938, 11.05.1938; 14 Briefe zwischen der Journal of Criminal Psychopathology, Woodbourne und Max Horkheimer,1940-1941; 1 Brief vom Journal of Philosophy and Phenomenological Research Bufallo N.Y. an Max Horkheimer, 19.11.1940; 1 Brief an das Jüdisches Schwesternheim Stuttgart an Max Horkheimer, 29.12.1937; 1 Brief von Jean Juget an Max Horkheimer, 25.11.1935; 2 Briefe zwischen der Juilliard School of Music New York und Theodor W. Adorno, 17.07.1940, 18.07.1940; 2 Briefe zwischen Gustave S. Juliber und Max Horkheimer, 09.10.1938, 01.11.1938;
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von J. Wolfsohn
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von J. Wolfsohn
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The human and shark Na–K–Cl cotransporters (NKCC), although 74% identical in amino acid sequence, exhibit marked differences in ion transport and bumetanide binding. We have utilized shark–human chimeras of NKCC1 to search for regions that confer the kinetic differences. Two chimeras (hs3.1 and its reverse sh3.1) with a junction point located at the beginning of the third transmembrane domain were examined after stable transfection in HEK-293 cells. Each carried out bumetanide-sensitive 86Rb influx with cation affinities intermediate between shark and human cotransporters. In conjunction with the previous finding that the N and C termini are not responsible for differences in ion transport, the current observations identify the second transmembrane domain as playing an important role. Site-specific mutagenesis of two pairs of residues in this domain revealed that one pair is indeed involved in the difference in Na affinity, and a second pair is involved in the difference in Rb affinity. Substitution of the same residues with corresponding residues from NKCC2 or the Na-Cl cotransporter resulted in cation affinity changes, consistent with the hypothesis that alternative splicing of transmembrane domain 2 endows different versions of NKCC2 with unique kinetic behaviors. None of the changes in transmembrane domain 2 was found to substantially affect Km(Cl), demonstrating that the affinity difference for Cl is specified by the region beyond predicted transmembrane domain 3. Finally, unlike Cl, bumetanide binding was strongly affected by shark–human replacement of transmembrane domain 2, indicating that the bumetanide-binding site is not the same as the Cl-binding site.
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Inclui notas bibliográficas
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Inclui notas explicativas, bibliográficas e bibliografia
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Tree rings have been used in various applications to reconstruct past climates as well as to assess the effects of recent climatic and environmental change on tree growth. In this paper we briefly review two ways that tree rings provide information about climate change and CO2: (i) in determining whether recent warming during the period of instrumental observations is unusual relative to prior centuries to millennia, and thus might be related to increasing greenhouse gases; and (ii) in evaluating whether enhanced radial growth has taken place in recent decades that appears to be unexplained by climate and might instead be due to increasing atmospheric CO2 or other nutrient fertilization. It is found that a number of tree-ring studies from temperature-sensitive settings indicate unusual recent warming, although there are also exceptions at certain sites. The present tree-ring evidence for a possible CO2 fertilization effect under natural environmental conditions appears to be very limited.
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Los carbapenémicos son los antibióticos β-lactámicos de más amplio espectro activos frente a microorganismos grampositivos, gramnegativos y anaerobios. Estos agentes mantienen su actividad frente a enterobacterias productoras de β-lactamasas de espectro extendido (BLEE) o de cefalosporinasas AmpC. Dentro de las enterobacterias, la resistencia a los carbapenémicos está mediada principalmente por la producción de diferentes tipos de carbapenemasas, aunque esta resistencia también puede ser debida a una combinación pérdida de porinas más enzimas BLEE o una hiperexpresión de AmpC. Las carbapenemasas representan la familia de β-lactamasas más versátil, con un amplio espectro. La mayoría de estas enzimas reconocen e hidrolizan a casi todos los β- lactámicos y son resistentes a la acción de los inhibidores de los β-lactámicos. Dentro de las enterobacterias, las carbapenemasas se aíslan principalmente en K. pneumoniae y en menor medida en E. coli y otras especies, con una prevalencia más alta en el sur de Europa y Asia que en otras partes del mundo. Las carbapenemasas de la clase A, que pertenecen al grupo 2f de Bush-Jacoby, se pueden dividir en 5 grupos en base a su filogenética: GES, KPC, SME, IMI y NMCA. Las enzimas SME, NMC e IMI están codificadas en cromosómas mientras que las enzimas GES y KPC se encuentran codificadas en plásmidos. El gen blaKPC está asociado el transposón Tn4401. Clínicamente, el grupo que más interés tiene es el de las enzimas KPC. Existen 11 tipos descritos...
Germany and the Eurocrisis: The timing of politics and the politics of timing. ACES Cases No. 2014.3
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This paper speculates on the future of the euro. It uses Germany as a prism for the discussion about what might be done next to bolster the Euro. Researching the future—always a challenging task—is made harder when multiple state actors contend for prominence on the basis of shifting coalitions at home, all while interacting at an international level. That said, almost everyone accepts that German choices will play the central role in the path ultimately chosen. This paper thus foregrounds Germany’s role in shaping the way ahead, and it does so through an explicitly political framework focused primarily on the electoral implausibility of an alternative German policy course.
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Through a case study of the diffusion of the celebrated West Gennan "dual system" of vocational training to the territory of the fonner German Democratic Republic, we develop the argument that local sociopolitical relations matter crucially for the successful transfer and implementation of institutional arrangements. Notwithstanding massive levels of government funding, the presence of complementary supports, and the concerted efforts of Germany's social partners, the dual system is experiencing significant difficulties in the new federal states of the East. These difficulties are not due simply to the particular politics of unification (the wholesale transfer of West German institutions whether or not they were appropriate to Eastern Germany) nor even simply to the paucity of dynamic private firms capable of and willing to train new apprentices. The difficulties stem also from the under lying weaknesses of the East German sociopolitical infrastructure on which the entire dual system rests. This. hy pothesis is elaborated and substantiated through a range of data on training in the East and especially through the use of detailed case studies of Leipzig and Chemrutz.
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Back Row: Steve King, Ed Pollister, Ed Wojtys, Mike Lantry, Jeff Spahn, Carl Russ, Kurt Kampe, Mark Jacoby, Tom Jenson
8th Row: Rick VanTongeren, Rick Jekel, Glenn Franklin, Lin Hardin, Dennis Franks, Bill Hoban, Roy Burks, Dave Metz, Mark McClain
7th Row: Dave Brown, Dennis Franklin, Gil Chapman, Jeff Perlinger, C.J. Kupec, Greg DenBoer, Steve Strinko, Chuck Heater, Pat Tumpane
6th Row: Norm Long, John Carpenter, Larry Banks, Kevin Masterson, Jim Lyall, Doug McKenzie, Jim Johnston, James Armour, John Thomas
5th Row: Jon Cederberg, Dave Brandon, Mike Day, Art Fediuk,John Cherry, Greg Koss, Don Warner, Ron Szydlowski,
4th Row: Larry Johnson, Walt Sexton, Craig Mutch, Gary Hainrihar, Doug Trozak, Walt Williamson, Don Coleman, Jovan Vercel, Barry Dotzbauer
3rd Row: Dave Elliott, Tom Slade, Harry Banks, Kevin Casey, Mike Hoban, Paul Seal, Dave Gallalgher, Ed Shuttlesworth, Bob Thornbladh, Tom Drake, Larry Gustafson
2nd Row: John Pighee, Jerry Schumacher, Tom Kee, Tom Coyle, Fred Grambau, Paul Seymour, Clint Spearman, Bill Hart, Greg Ellis, Tony Smith, Clint Haslerig
Front Row: Tom Poplawski, Larry Cipa, John Daniels, Don Eaton, Dave Zucarelli, Gary Coakley, Randy Logan, David (Bo) Rather, Alan Walker, Jim Coode