Estudios etnobotánicos en Chile para descubrir nuevos compuestos medicinales

[ES] Basándose en estudios etnobotánicos, un grupo de científicos de la Facultad Danesa de Farmacia, Universidad de Copenhagen, Dinamarca, ha realizado estudios etnofarmacológicos "In vitro" e "In vivo" de las plantas medicinales usadas tradicionalmente por los Huilliches. Los resultados como antioxidantes, antidiabéticos, antihipertensión y antimicrobiales son promisorios. Sus principales componentes con actividad biológica han sido identificados. Extracto y aislado componente de Lomatia hirsuta muestra total inhibición de Candida albicans. Extractos y componentes de especies como Drimys winteri, Crinodendron hookerianum, Persea lingue, Coriaria ruscifolia y otras inhiben varias bacterias resistentes a los antibioticos.

Rekonstruktion der eiszeitlichen Verbreitung und Artbildung vier alpiner Primeln durch Artenverbreitungsmodelle und Phylogeographie

Aim: Previous studies revealed that diversification events in the western clade of the alpine Primula sect. Auricula were concentrated in the Quaternary cold periods. This implies that allopatric speciation in isolated glacial refugia was the most common mode of speciation. In the first part of the present dissertation, this hypothesis is further investigated by locating refugial areas of two sister species, Primula marginata & P. latifolia during the last glacial maximum, 21,000 years ago. In the second part, the glacial and postglacial history of P. hirsuta and P. daonensis is investigated. Location: European Alps. Methods: Glacial refugia were located using species distribution models, which are projected to last glacial maximum climate. These refugia are validated with geographic distribution patterns of intra-specific genetic diversity, rarity and variation. Results 1) Speciation: Glacial refugia of the sister taxa Primula marginata and P. latifolia were largely separated, only a small overlapping zone at the southern margin of the former glacier in the Maritime Alps exists. This overlapping zone is too small to indicate sympatric speciation. The largely separated glacial distribution of both species rather confirms our hypothesis of allopatric speciation in isolated glacial refugia. Results 2) Glacial and postglacial history: Surprizingly, the modelled potential refugia of three out of four Primula species are situated within the former ice-shield, except for P. marginata. This indicates that peripheral and central nunataks played an important role for the glacial survival in P. latifolia, P. hirsuta and P. daonensis, while peripheral refugia outside the maximum extend of the glacier were crucial in P. marginata. In P. hirsuta and P. latifolia SDMs allowed to exclude several hypothetical refugial areas that overlap with today’s distribution as potential refugia for the species. In P. marginata, hypothetical refugial areas at the periphery of the former ice-shield that overlap with today’s distribution were confirmed by the models. The results from the SDMs are confirmed by population genetic patterns in three out of four species. P. daonensis represents an exception, where population genetic data contradict the SDMs. Main conclusions: Species distribution models provide species specific scenarios of glacial distribution and postglacial re-colonization, which can be validated using population genetic analyses. This combined approach is useful and helps to understand the complex processes that have lead to the genetic and floristic patterns of biodiversity that is found today in the Alps.

Stable isotope record of planktonic foraminifera from sediment core MD96-2085

A high-resolution (~4-5cm/kyr) giant piston core record (MD962085) retrieved during an IMAGES II-NAUSICAA cruise from the continental slope of the southeast Atlantic Ocean reveals striking variations in planktonic foraminifer faunal abundances and sea-surface temperatures (SST) during the past 600 000 yr. The location and high-quality sedimentary record of the core provide a good opportunity to assess the variability of the Benguela Current system and associated important features of the ocean-climate system in the southeast Atlantic. The planktonic foraminifer faunal abundances of the core are dominated by three assemblages: (1) Neogloboquadrina pachyderma (right coiling) + Neogloboquadrina dutertrei, (2) Globigerina bulloides, and (3) Globorotalia inflata. The assemblage of N. pachyderma (right coiling) + N. dutertrei shows distinctive abundance changes which are nearly in-phase with glacial-interglacial variations. The high abundances of this assemblage are associated with major glacial conditions, possibly representing low SST/high nutrient level conditions in the southwestern Africa margin. In contrast, the G. bulloides and G. inflata assemblages show greater high-frequency abundance change patterns, which are not parallel to the glacial-interglacial changes. These patterns may indicate rapid oceanic frontal movements from the south, and a rapid change in the intensity of the Benguela upwelling system from the east. A single episode of maximum abundances of a polar water species N. pachyderma (left coiling) occurred in the beginning of stage 9 (~340-330 kyr). The event of the maximum occurrence of this species shown in this record may indicate instability in the Benguela coastal upwelling, or the Antarctic polar front zone position. A winter season SST estimate using transfer function techniques for this record shows primarily glacial-interglacial variations. The SST is maximal during the transitions from the major glacial to interglacial stages (Terminations I, II, IV, V), and is associated with the abundance maxima of a warm water species indicator Globigerinoides ruber. Cross-spectral analyses of the SST record and the SPECMAP stack reveal statistically significant concentrations of variance and coherencies in three major orbital frequency bands. The SST precedes changes in the global ice volume in all orbital frequency bands, indicating a dominant southern Hemispheric climate effect over the Benguela Current region in the southeast Atlantic.

Cenozoic planktonic foraminifera in the Goban Spur Region

Cenozoic planktonic foraminiferal biostratigraphy at DSDP-IPOD Leg 80 sites documents the existence of regionwide stratigraphic gaps in the Paleocene and middle Miocene. Episodes of carbonate dissolution also occurred during the Paleocene at several sites, particularly at Site 549, where destruction of foraminiferal tests may obscure evidence of an unconformity. The middle Miocene hiatus is apparent at each site where Neogene sediments were continuously cored. Upper Miocene sediments at Site 550 (the only abyssal site) are characterized by moderate to extensive dissolution of planktonic foraminifers, but they contain abundant specimens of Bolboforma that mark this stratigraphic interval (von Daniels and Spiegler, 1974, doi:10.1007/BF02986990; Roegl, 1976, doi:10.2973/dsdp.proc.35.133.1976; Murray, 1979, doi:10.2973/dsdp.proc.48.116.1979; Müller et al., 1985, doi:10.2973/dsdp.proc.80.117.1985). Although foraminiferal evidence is not conclusive, nannofossils indicate a widespread Oligocene unconformity (Müller, 1985). Several oceanographic factors, not just simple sea-level change, probably interacted to produce these regional unconformities. There are also dramatic differences in the Cenozoic sedimentary record among Leg 80 sites, indicating that each has had a distinct geologic history. The thickness of the Cenozoic section varies from 100 m at Site 551 to 471 m at Site 548. The thickness of individual chronostratigraphic units also varies, as do the number and stratigraphic position of unconformities other than those mentioned. Differences in the stratigraphic record from site to site across the continental slope result from (1) location in separate half-graben structures, (2) varying location across the developing margin, and (3) difference in position relative to the seaward edge of the enclosing half-graben. Except for turbidites, deposition at Site 550 (abyssal) was largely independent of developments on the continental slope; but it was affected by oceanographic events widespread in the North Atlantic.

Planktonic foraminifera record and SST reconstruction for the last 130 ka in the Western South Atlantic

This work reconstructs Late Quaternary paleoceanographic changes in the western South Atlantic Ocean based on sedimentary core GL-77, recovered from the lower continental slope in the Campos basin, offshore SE Brazil. The studied interval comprises the last 130 ka. Changes in sea surface temperature (SST) and paleoproductivity were estimated using the total planktonic foraminiferal fauna and oxygen isotope analyses. The age model was based on the oxygen isotope record, biostratigraphic datums and AMS 14C dating. It was observed that the Pleistocene/Holocene transition occurs within Globorotalia menardii Biozone Y, and is not coeval with the base of Biozone Z. The range between summer and winter SST estimates is larger during the glacial period compared to interglacials. Three peaks of low SST around 70, 50 - 45 and 20 ka coincided with periods of enhanced SE trade winds. Despite faunal differences between the last interglacial (MIS 5e) and the Holocene, our SST estimates suggest that SSTs did not differ significantly between these intervals.