Transformaciones básicas de las funciones

En el desarrollo de esta actividad se discute cómo se transforma una función, de la cual se conoce su representación gráfica y no su representación algebraica. La actividad consiste en un estudio de la gráfica de una función prototipo totalmente descontextualizada. Se propone la composición de funciones, operaciones entre gráficas y su relación con algunas formas analíticas asociadas al variar algunos de sus parámetros, para mirar el comportamiento global tanto de la función compuesta, como de la familia de funciones resultantes; que permita relacionar la representación gráfica de una función compuesta con las funciones que la componen y explorar patrones en las familias de éstas y así poder predecir el comportamiento de una función cualquiera bajo este tipo de transformaciones.

Fast divide-and-conquer algorithms for preemptive scheduling problems with controllable processing times - a polymatroid optimization approach

We consider a variety of preemptive scheduling problems with controllable processing times on a single machine and on identical/uniform parallel machines, where the objective is to minimize the total compression cost. In this paper, we propose fast divide-and-conquer algorithms for these scheduling problems. Our approach is based on the observation that each scheduling problem we discuss can be formulated as a polymatroid optimization problem. We develop a novel divide-and-conquer technique for the polymatroid optimization problem and then apply it to each scheduling problem. We show that each scheduling problem can be solved in $ \O({\rm T}_{\rm feas}(n) \times\log n)$ time by using our divide-and-conquer technique, where n is the number of jobs and Tfeas(n) denotes the time complexity of the corresponding feasible scheduling problem with n jobs. This approach yields faster algorithms for most of the scheduling problems discussed in this paper.

Press, politic, and social order in Buenos Aires during the 1850s

The paper examines some reflections and discussions about the role and nature of the press that took place in Buenos Aires during the 1850s, referring to the difficulties involved in congenial freedom and order. This was caused by the fact that the press was considered a pillar of republican and civilized societies, but also an agent capable of corroding the social and political order.

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by genotyping of top association signals in 56,682 additional individuals. This analysis identified 13 loci newly associated with CAD at P < 5 x 10(-8) and confirmed the association of 10 of 12 previously reported CAD loci. The 13 new loci showed risk allele frequencies ranging from 0.13 to 0.91 and were associated with a 6% to 17% increase in the risk of CAD per allele. Notably, only three of the new loci showed significant association with traditional CAD risk factors and the majority lie in gene regions not previously implicated in the pathogenesis of CAD. Finally, five of the new CAD risk loci appear to have pleiotropic effects, showing strong association with various other human diseases or traits.

Promoting Harmonious Relations and Equitable Well-Being: Peace Psychology and “Intractable” Conflicts

The chapter explores Bar-Tal’s legacy in relation to key concepts, perspectives, and findings that comprise the growing field of peace psychology, specifically the promotion of sustainable peace through the indivisible constructs of harmonious relations and equitable wellbeing. Analyzed through a peace psychology lens, Bar-Tal’s work highlights both the barriers to and bridges for achieving sustainable peace. Central concepts from his work, such as fear, insecurity, and an ethos of conflict, demonstrate key obstacles to fostering harmonious intergroup relations based on social justice. Bar-Tal’s work also identifies processes that can overcome these barriers, which is consistent with peace psychology’s emphasis on the development of constructive responses to violence and conflict. For example, the chapter outlines how confidence-building mechanisms, mutually respectful identities, and reconciliation processes, may help foster an ethos of peace that can be embedded in the structure of societies through peace education. The chapter concludes with implications and suggestions for future research, with a focus on the role of young people in settings of prolonged intergroup division and generational approaches to peacebuilding, as conceptualized through a peace psychology lens.

A organização pedagógica das universidades sénior do distrito de Évora

O objetivo principal deste estudo consiste em “Conhecer e caracterizar os modelos pedagógicos do ensino não formal e informal nas Universidades Sénior do distrito de Évora”. Para concretizar este objetivo, foram selecionadas três Universidades Sénior do distrito de Évora: Universidade Sénior de Évora, Universidade Sénior de Reguengos de Monsaraz e a Universidade Popular Túlio Espanca-Pólo de Viana do Alentejo, para conhecer a respetiva oferta formativa e caracterizar o padrão curricular da cada instituição. Por último, pretendeu-se caraterizar o público-alvo e destinatários desta Oferta. Este ensino não formal é desenvolvido por professores que dedicam o tempo a elaborar projetos e atividades nestas Universidades Sénior, contribuindo assim para a aprendizagem nas diversas áreas, como as artes e humanidades. A organização pedagógica destas instituições apresenta inúmeras diferenças na estrutura interna e existe uma discrepância considerável, no número professores e alunos que frequentam estas US. A forma como as US estão integradas na comunidade, os projetos e atividades que desenvolvem, são de certa forma o modelo da sua evolução e o progresso; ### ABSTRACT: THE PEDAGOGICAL ORGANIZATION OF SENIOR UNIVERSITIES IN ÉVORA'S DISTRICT The main purpose of this study will be to “Know and describe the pedagogical models of formal and non-formal education in Senior Universities from Évora’s district”. To fulfill this purpose we selected three Senior Universities of the district, such as Senior University of Évora, Senior University of Reguengos de Monsaraz and the Popular Tulio Espanca University - Campus of Viana do Alentejo. In this way it will be possible to know each educational offer and to describe the curricular pattern of each institution. It will also allow us to describe the target public of the Senior Universities in Évora’s district . This non-formal education is developed by teachers who dedicate their time to developing projects in these Senior Universities, making a contribution to learning several areas, such as arts and social sciences. The pedagogical organization of these institutions shows us that there are several differences between them and that there is a considerable discrepancy in the number of teachers and students that come to such institutions. The way in which they are integrated in the community, their projects and activities, are, in a way, the model of their evolution and progresso.

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or  ≥90 mm Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3-GUCY1B3, NPR3-C5orf23, ADM, FURIN-FES, GOSR2, GNAS-EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function. We also observed associations with blood pressure in East Asian, South Asian and African ancestry individuals. Our findings provide new insights into the genetics and biology of blood pressure, and suggest potential novel therapeutic pathways for cardiovascular disease prevention.

Cartas de Cicerón con breves argumentos y notas

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M. Tullij Ciceronis orationes duodecim selectae, in usum GymnasiorumSocietatis Jesu, quibus accesserunt Compendium Rhetoricae R. P. Cypriani Soarij ... et Lacrymae Sancti Petri R. P. Sidronij Hoschij

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Oraciones escogidas de M. T. Cicerón.

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Oraciones escogidas de M. T. Cicerón.

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Ciceronis opera : cum delectum commentariorum in usum serenissimidelphini

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Cicerón

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Ciceron y Demostenes : obrita dedicada a los alumnos de la cátedrade mayores del seminario conciliar de esta ciudad

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Oraciones escogidas de M. T. Cicerón

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