A voyage of discovery to the North Pacific Ocean, and round the world : in which the coast of north-west America has been carefully examined and accurately surveyed : Undertaken by His Majesty's command, principally with a view to ascertain the existence of any navigable communication between the North Pacific and North Atlantic Oceans, and performed in the years 1790, 1791, 1792, 1793, 1794, and 1795, in the Discovery sloop of war, and armed tender Chatham, under the command of Captain George Vancouver : in three volumes, Vol. I.

Mode of access: Internet.

Convention entre les cours de Vienne, de St. Pétersbourg, de Londres et de Berlin, pour fixer le sort des sept îles Ioniennes; signée à Paris le 5 novembre 1815.

With the ratification in Latin by Francis I, dated Venice, December 17, 1815.

The works of George Berkeley,

Life of the author is by Joseph Stock.

Authentic and impartial memoirs of Her Late Majesty, Charlotte, Queen of Great Britain and Ireland : containing a faithful retrospect of her early days, her marriage, coronation, correspondence, illness, death, funeral obsequies, &c. &c. Interspersed with occasional anecdotes of the royal family, and other illustrious personages. Including various interesting and original particulars, never before published /

Added t. p.: Memoirs of Her Late Majesty, Queen Charlotte.

Colonel John Butler (Niagara)/St. Catharines District Branch of the United Empire Loyalists fonds

United Empire Loyalist is an honour given to American Loyalists who came to British North America and the British Colonies to show their loyalty to King George III after the British defeat in the American Revolution. The Loyalists settled in Quebec, Ontario, Nova Scotia and modern day New Brunswick. The Colonel John Butler (Niagara) Branch (formerly the St. Catharines and District Branch) has origins which date as far back as 1898. A branch was organized in Virgil by Captain John D. Servos, but was unsuccessful. In 1905 there was another attempt to form a branch, but the war of 1914-1918 resulted in this branch becoming inactive. In 1914, an Act of Parliament incorporated the United Empire Loyalists’ Association of Canada. The St. Catharines and District Branch was formed in 1921. This branch remained active, and in 1992 they changed their name to The Colonel John Butler (Niagara) Branch. The Loyalists also have a strong focus on genealogy. All descendants are eligible to use UE (which stands for Unity of the Empire) after their names. source: http://www.coljohnbutleruel.com

Alteration of GSH level, gene expression and cell transformation in NIH3T3 cells by chronic exposure to low dose of arsenic

It is well established that arsenic toxicity is postulated to be primarily due to the binding of As(III) to sulfhydryl-containing enzymes. However, the mechanism of carcinogenesis induced by arsenic is still unclear. The interaction of arsenic with GSH and related enzymes seems a very important issue regarding mechanism of arsenical induced toxicity or carcinogenesis. The purpose of this work is to investigate the effect of chronic exposure to low dose of As(III) on GSH level, gene expression and cell transformation in NIH3T3 cells. The results showed that long-term, low dose arsenic treatment makes 3T3 cell more resistant to acute arsenic treatment. There were morphology changes after long-term arsenic treatment. First, partially immortalized 3T3 cell became immortalized. In addition, the cells were doubling more quickly than the control cells and attained higher density than the control cells at confluence. Second, cells treated with 0.1 µ.M As(III) exhibited anchorage-independent growth. Arsenic could enhance GSH level at 0.5 -10 µM dose of arsenic in 24 h treatment and decrease it at 25 µM and above. In long-term treatment with low dose of arsenic, GSH levels were decreased. As(I1I) can increase both glutathione S-transferase (GST) and glutathione reductase (GR) activities at low dose (0.5-10 M), but decreased GST and GR activities at 25 M and higher dose of arsenic, while in long-term As(III) treatment, GST and GR activities are increased. Both long-term and short-term treatments with As(III) can induce GR gene expression. GPx mRNA levels were decreased both in acute and chronic arsenic treated cells. Chronic treatment with As(III) also decreased the p53 mRNA level. Taken together, our results suggest that As(III) can alter GST, GR enzyme activities as well as GSH level and related gene expression both in long-term and short-term treatment but in a different manner in different doses. Alteration of cellular GSH level by As(III) might play all important role in gene expression and arsenic induced cell transformation.

Beitrag zur Geschichte der Verfolgung der Juden im 19ten Jahrhundert durch Schriftsteller : ein Sendschreiben an die Frau Kammerherrin von der Recke, geb. Gräfin v. Medem

von David Friedländer

Geschichte, Religionsgrundsätze und staatsbürgerliche Verhältnisse der Juden : ein Noth- u. Hülfsbüchlein f. d. gegenwärtige Zeit

von Ferdinand Schubert

Oratio salutatoria et oratio valedictoria, ca. 1763

Undated and unattributed handwritten Latin salutatory and valedictory orations composed for the Harvard College Commencement. A modern note with the materials suggests Nathaniel Sparhawk (Harvard AB 1765) as the author, but the author was more likely Joseph Hooper (Harvard AB 1763), who delivered the orations for the 1763 Harvard Commencement. While the documents are undated, textual clues include mention of the command of George III in recent war against France and Spain, suggesting the speech was written soon after the Treaty of Paris which was signed in February 1763 to end the Seven Years' War. The speech also celebrates Harvard Tutor William Kneeland, who resigned from his position in July 1763, and mentions the illness of Professor Edward Wigglesworth (who died before the 1765 Commencement). The text also mentions Professor John Winthrop and Massachusetts Governor Francis Bernard.

Inqvisitionvm ad capellam domini regis retornatarvm, qvae in pvblicis archivis Scotiae adhvc servantvr, abbreviatio [1546-1700].

University at Buffalo copy lacks v. 1-2, 4.

Pages & portraits from the past, being the private papers of Sir William Hotham

v.1. Concerning the writer. Early narrative. Under Hood and Nelson. The mutiny at the Nore. Camperdown and after. Life at the Cape. Portraits under George III. The days of Napoleon.--v.2. The days of Napoleon. Portraits after Waterloo. Portraits under George IV. Portraits under William IV. The days of Victoria.

Works of Henry, lord Brougham ...

[v. 1] Lives of philosophers of the time of George III. 1855.--[v. 2] Lives of men of letters of the time of George III. 1855.--[v. 3]-5. Historical sketches of statesmen who flourished in the time of George III. 1856-58.--v. 6. Natural theology ... 1856.--v. 7. Rhetorical and literary dissertations and addresses. 1856.--v. 8. Historical and political dissertations. 1857.--v. 9-10. Speeches on social and political subjects. 1857.--v. 11. The British constitution: its history, structure, and working. 1861.

Histoire philosophique de la révolution de France : depuis la première Assemblée des Notables jusqu'à la paix de Presbourg /

Contiene: t. 1, t. 2, t. 3, t. 6, t. 7.

Nouvel Abrégé chronologique de l'histoire de France : contenant les evénements de notre histoire, depuis l'entrée des Francs dans les Gaules ... /

Mode of access: Internet.