The longitudinal course of gross motor activity in schizophrenia - within and between episodes

Schizophrenia is associated with heterogeneous course of positive and negative symptoms. In addition, reduced motor activity as measured by wrist actigraphy has been reported. However, longitudinal studies of spontaneous motor activity are missing. We aimed to explore whether activity levels were stable within and between psychotic episodes. Furthermore, we investigated the association with the course of negative symptoms. In 45 medicated patients, we investigated motor behavior within a psychotic episode. In addition, we followed 18 medicated patients across 2 episodes. Wrist actigraphy and psychopathological ratings were applied. Within an episode symptoms changed but activity levels did not vary systematically. Activity at baseline predicted the course of negative symptoms. Between two episodes activity recordings were much more stable. Again, activity at the index episode predicted the outcome of negative symptoms. In sum, spontaneous motor activity shares trait and state characteristics, the latter are associated with negative symptom course. Actigraphy may therefore become an important ambulatory instrument to monitor negative symptoms and treatment outcome in schizophrenia.

THE CLINICAL AND PARASITOLOGIC COURSES OF PLASMODIUM FALCIPARUM AND PLASMODIUM VIVAX INFECTIONS IN HUMANS: AN ANALYSIS OF 432 EPISODES OF INDUCED MALARIA IN THE JESSUP VOLUNTEER STUDIES, 1966-1975

The clinical records of 432 P. falciparum and P. vivax infected volunteer male inmates of the Maryland House of Corrections in Jessup, Maryland, were studied to determine (1) the clinical and parasitologic courses of infections in both parasite species, and (2) the influence of previous homologous and/or heterologous strain exposures on subsequent infections. The clinical and parasitologic courses of infection with both P. falciparum and P. vivax species indicated that: (a) there were characteristic strain related differences between P. falciparum and P. vivax. P. falciparum strains were more apt to cause severe infections than P. vivax strains. (b) Blood-induced infections produced significantly shorter prepatent and incubation periods than mosquito-induced. (c) Blacks tolerated the infections better than whites and, (d) homologous and heterologous strain immunities persisted with previous malaria history. In previously exposed cases, clinical manifestations were moderate, peak fever lowered, and peak parasitemias limited. (e) Anti-malarial drugs were effective in reducing sexual and asexual forms of the malaria parasite, and limiting peak fevers, irrespective of method of induction, race, parasite strain and species, and drug type used.^ Given these findings, and the current worldwide resurgence of malaria, this study has major implications in terms of setting malaria control and public health policies in both developed and developing countries.^

Changes in learning-resource use across physicians' learning episodes*

Introduction: This study explores the numbers of learning resources physicians use at each stage in self-directed learning episodes addressing general problems.

An Investigation of Ozone Related Data and Development of a Model to Evaluate Ozone Episodes for Exceptional Event Criteria

The EPA promulgated the Exceptional Events Rule codifying guidance regarding exclusion of monitoring data from compliance decisions due to uncontrollable natural or exceptional events. This capstone examines documentation systems utilized by agencies requesting data be excluded from compliance decisions due to exceptional events. A screening tool is developed to determine whether an event would meet exceptional event criteria. New data sources are available to enhance analysis but evaluation shows many are unusable in their current form. The EPA and States must collaborate to develop consistent evaluation methodologies documenting exceptional events to improve the efficiency and effectiveness of the new rule. To utilize newer sophisticated data, consistent, user-friendly translation systems must be developed.

Episodes of French history.

Mode of access: Internet.

The cankerworm : being episodes of a woman's life.

Mode of access: Internet.

The romance of the ranks; or, Anecdotes, episodes, and social incidents of military life.

Mode of access: Internet.

Episodes of insect life.

In three series.

The gentlemen in the white hats; dramatic episodes in the history of the Texas rangers,

Mode of access: Internet.

Episodes of French history, during the consulate and the first empire.

Title vignette.

Jennifer Lorn : a sedate extravaganza : illuminating episodes in the lives of the Hon. Gerald Poyngard and his bride /

First ed. with uncorrected t.p., which was subsequently excised and a cancellans (with "Poyngard" corrected to "Poynyard" and 4th word of Latin quotation changed from "tegmine" to "tegmina") tipped in on stub of original t.p.

Current episodes; New York State Extension Service.

Dec. 1960 incorrectly marked v. 22; v. 22 omitted in vol. enumeration.

Anecdotes of the aristocracy, and episodes of ancestral story.

Mode of access: Internet.

Address to the veterans of the Mexican war. Embodying a historical contrast of the two great political parties of the United States on vital issues, with personal reminiscences and other pertinent episodes. Also: an appendix of three chapters, entitled "The California democratic state club pilloried."--"A new plundercrat organ disguised in the garb of democracy."--"To the greenback-labor voters."

Mode of access: Internet.

Episodes from Sans famille /

Mode of access: Internet.