Memoirs of the life of Anne Boleyn, queen of Henry VIII;

Mode of access: Internet.

Memorial de su Magestad [sic] católica el Señor D. Felipe IV, presentado a la Santidad del Papa Urbano VIII en la embajada a que fueron a Roma en el año de 1633 D. Fray Domingo Pimentel, Obispo de Córdoba y D. Juan Chumacero y Carrillo... ; Respuesta dada de orden de Su Santidad por Monseñor Miraldi, Secretario de Breves ; y replica de los señores Pimentel y Chumacero...

Tít. de la cub.: Memorial del Rey Don Felipe IV, presentado al Papa Urbano VIII.

Ecclesiastical memorials, relating chiefly to religion, and the reformation of it, and the emergencies of the Church of England, under King Henry VIII. King Edward VI. and Queen Mary I. with large appendixes, containing original papers, records, &c. /

Binder's title: Strype's works, VIII-XIII.

Zwo der berühmtesten päbstlichen Bullen In coena Domini und Unigenitus /

Signatures: : *⁴ A-D⁴.

The divorce of Catherine of Aragon : the story as told by the imperial ambassadors resident at the court of Henry VIII /

"Being a supplementary volume to the author's History of England."

Sanctissimi D. N. Pii PP. IX. Epistola encyclica data die VIII decembris MDCCCLXIV. ad omnes catholicos antistites unacum syllabo praecipuorum aetatis nostrae errorum et actis pontificis ex quibus excerptus est syllabus.

Mode of access: Internet.

A treatise on the pretended divorce between Henry VIII. and Catharine of Aragon,

Mode of access: Internet.

Regestvm Clementis papae v [annus primus-annus nonus]; ex vaticanis archetypis sanctissimi domini nostri Leonis XIII pontificis maximi ivssv et mvnificenta nvnc primvm editvm cvra et stvdio monachorvm ordinis s. Benedicti anno 1884-[1888]

Accompanied by "Tables des Registres de Clément V, pub. par les bénédictins, établies par Yvonne Lanhers sous la direction de Robert Fawtier. Table chronologique, table des incipit." (viii, 68 p. 33 cm (Bibliothèque des écoles françaises d'Athènes et de Rome. 3 sér.)) Published: Paris, E. de Boccard, 1948.

Memoirs of the life of Anne Boleyn, Queen of Henry VIII /

Mode of access: Internet.

Lettres de Henri VIII à Anne Boleyn, avec la traduction; précédées d'une notice historique sur Anne Boleyn.

Mode of access: Internet.

Fr. Ragvelli ... Commentarivs, ad constitvtiones et decisiones Ivstiniana qvae XII. lbris[!] Codicis continentur; et ad priores titvlos libri VIII. Cod ...

Mode of access: Internet.

A revisit to Pope's cohort analysis

Gulland's [Gulland, J.A., 1965. Estimation of mortality rates. Annex to Arctic Fisheries Working Group Report (meeting in Hamburg, January 1965). ICES. C.M. 1965, Doc. No. 3 (mimeographed)] virtual population analysis (VPA) is commonly used for studying the dynamics of harvested fish populations. However, it necessitates the solving of a nonlinear equation for the instantaneous rate of fishing mortality of the fish in a population. Pope [Pope, J.G., 1972. An investigation of the accuracy of Virtual Population Analysis using cohort analysis. ICNAF Res. Bull. 9, 65-74. Also available in D.H. Cushing (ed.) (1983), Key Papers on Fish Populations, p. 291-301, IRL Press, Oxford, 405 p.] eliminated this necessity in his cohort analysis by approximating its underlying age- and time-dependent population model. His approximation has since become one of the most commonly used age- and time-dependent fish population models in fisheries science. However, some of its properties are not well understood. For example, many assert that it describes the dynamics of a fish population, from which the catch of fish is taken instantaneously in the middle of the year. Such an assertion has never been proven, nor has its implied instantaneous rate of fishing mortality of the fish of a particular age at a particular time been examined, nor has its implied catch equation been derived from a general catch equation. In this paper, we prove this assertion, examine its implied instantaneous rate of fishing mortality of the fish of a particular age at a particular time, derive its implied catch equation from a general catch equation, and comment on how to structure an age- and time-dependent population model to ensure its internal consistency. This work shows that Gulland's (1965) virtual population analysis and Pope's (1972) cohort analysis lie at the opposite end of a continuous spectrum as a general model for a seasonally occurring fishery; Pope's (1972) approximation implies an infinitely large instantaneous rate of fishing mortality of the fish of a particular age at a particular time in a fishing season of zero length; and its implied catch equation has an undefined instantaneous rate of fishing mortality of the fish in a population, but a well-defined cumulative instantaneous rate of fishing mortality of the fish in the population. This work also highlights a need for a more careful treatment of the times of start and end of a fishing season in fish population models.

Factor VIII-hydrolyzing IgG in acquired and congenital hemophilia

Anti-factor VIII (FVIII) inhibitory IgG may arise as alloantibodies to therapeutic FVIII in patients with congenital hemophilia A, or as autoantibodies to endogenous FVIII in individuals with acquired hemophilia. We have described FVIII-hydrolyzing IgG both in hemophilia A patients with anti-FVIII IgG and in acquired hemophilia patients. Here, we compared the properties of proteolytic auto- and allo-antibodies. Rates of FVIII hydrolysis differed significantly between the two groups of antibodies. Proline-phenylalanine-arginine-methylcoumarinamide was a surrogate substrate for FVIII-hydrolyzing autoantibodies. Our data suggest that populations of proteolytic anti-FVIII IgG in acquired hemophilia patients are different from that of inhibitor-positive hemophilia A patients.

Structural Studies of Analgesics and Their Interactions. VIII.* Rotational Isomerism and Disorder in the Crystal Structure of Meelofenamie Acid

Meclofenamic acid, C I4HIICI2NO2, probably the most potent among analgesic fenamates, crystallizes in the triclinic space group P1, with a = 8.569 (5), b = 8.954(8), c -- 9.371 (4) A, ct = 103.0 (2), fl -- 103.5 (2), y = 92.4 (2) ° , Z = 2, D m = 1.43 (4), D c = 1.41 Mg m -3. The structure was solved by direct methods and refined to R = 0.135 for 1062 observed reflections. The anthranilic acid moiety in the molecule is nearly planar and is nearly perpendicular to the 2,6-dichloro-3-methylphenyl group. The molecules, which exist as hydrogen-bonded dimers, have an internal hydrogen bond involving the imino and the carboxyl groups. The methyl group is disordered and occupies two positions with unequal occupancies. The disorder can be satisfactorily explained in terms of the rotational isomerism of the 2,6-dichloro-3-methylphenyl group about the bond which connects it to the anthranilic acid moiety and the observed occupancies on the basis of packing considerations.

Varied Immune Response to FVIII: Presence of Proteolytic Antibodies Directed to Factor VIII in Different Human Pathologies

The versatility of antibodies is demonstrated by the various functions that they mediate such as neutralization, agglutination, fixation of the complement and its activation, and activation of effector cells. In addition to this plethora of functions, antibodies are capable of expressing enzymatic activity. Antibodies with catalytic function are a result of the productive interplay between the highly evolved machinery of the immune system and the chemical framework used to induce them (antigens). Catalytic antibodies are immunoglobulins with an ability to catalyze the reactions involving the antigen for which they are specific. Catalytic immunoglobulins of the IgM and IgG isotypes have been detected in the serum of healthy donors. In addition, catalytic immunoglobulins of the IgA isotype have been detected in the milk of healthy mothers. Conversely, antigen-specific hydrolytic antibodies have been reported in a number of inflammatory, autoimmune, and neoplastic disorders. The pathophysiological occurrence and relevance of catalytic antibodies remains a debated issue. Through the description of the hydrolysis of coagulation factor VIII as model target antigen, we propose that catalytic antibodies directed to the coagulation factor VIII may play a beneficial or a deleterious role depending on the immuno-inflammatory condition under which they occur.