978 resultados para Charles II, King of Navarre, 1332-1387.
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No evidence that other volumes beyond vol. 1 were published.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Includes advertisement, p. 48.
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Text in English and Latin, and English and French, in parallel columns.
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"Materials for the history of the Popish plot": p. 405-411.
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Half-title of v. 4: Bohn's historical library.
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Digital image
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OBJECTIVE: The primary objective of this trial was to evaluate the response rate for trimetrexate in conjunction with 5-FU and leucovorin (LV) (= TFL) in the treatment of advanced gastric cancer in a phase II, cooperative group setting. METHODS: Patients with locally advanced, unresectable, or metastatic adenocarcinoma of the stomach received trimetrexate 110 mg/m IV over 60 minutes day 1, followed by 5-FU 500 mg/m IV bolus and LV 200 mg/m IV over 60 minutes day 2, followed by oral LV 15 mg every 6 hours x 7 doses, all weekly for 6 weeks followed by 2 weeks of rest, continued until progression. RESULTS: Characteristics for 37 eligible patients: median age 63 (range: 23-83); male/female: 69% of 31%; performance status 0/1/2 15/20/1. The confirmed response rate was 19%, and median overall survival was 6 months. Two patients died as a result of therapy, 1 because of infection without significant neutropenia, and 1 due to perforation of a responding gastric lesion. Seventy-two percent experienced grades 3 and 4 toxicity, most commonly diarrhea, fatigue, and lymphopenia. CONCLUSIONS: This regimen achieves response rates comparable to other 5-FU-based regimens, when used in treatment of incurable gastric cancer. Toxicity appears manageable.
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Mode of access: Internet.
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Mode of access: Internet.
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Contiene: Vol. 1 (1857. XXIII, 322 p.) -- Vol. 2 (1857. XI, 316 p.) -- Vol. 3 (1859. XII, 252, 24 p.)
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Mode of access: Internet.