Pfeiffer, Ganzfigurbildnis

Signatur des Originals: S 36/F01506

Ernest Birch, Brustbild

Signatur des Originals: S 36/F08215

Hermann Pfeiffer, Rollenbild, Kniestück

Signatur des Originals: S 36/F09513

Hermann Pfeiffer, Rollenbild

Signatur des Originals: S 36/F09514

Hermann Pfeiffer als Wilhelm Tell, {[N.N.], Rollenbild, Doppelbildnis

Signatur des Originals: S 36/F09515

Isidor Lotto, Louisa Pyne, Salvatore Marchesi, Mathilde Marchesi de Castrone, Harrison, Georges Jean Pfeiffer, {[N.N.], Gruppenbildnis

Signatur des Originals: S 36/F10944

The major allergens of birch pollen and cow milk, Bet v 1 and Bos d 5, are structurally related to human licocalin 2, enabling them to manipulate T-helper cells depending on their load with siderophore-bound iron

We conclude that Bet v 1 and Bos d 5 not only structurally mimic human LCN2, but also functionally by their ability to bind iron via siderophores. The apo-forms promote Th2 cells, whereas the holo-forms appear to be immunosuppressive. These results provide for the first time a functional understanding on the principle of allergenicity of major allergens from entirely independent sources, like birch and milk.

A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes

Intercellular signaling by fibroblast growth factors plays vital roles during embryogenesis. Mice deficient for fibroblast growth factor receptors (FgfRs) show abnormalities in early gastrulation and implantation, disruptions in epithelial–mesenchymal interactions, as well as profound defects in membranous and endochondrial bone formation. Activating FGFR mutations are the underlying cause of several craniosynostoses and dwarfism syndromes in humans. Here we show that a heterozygotic abrogation of FgfR2-exon 9 (IIIc) in mice causes a splicing switch, resulting in a gain-of-function mutation. The consequences are neonatal growth retardation and death, coronal synostosis, ocular proptosis, precocious sternal fusion, and abnormalities in secondary branching in several organs that undergo branching morphogenesis. This phenotype has strong parallels to some Apert's and Pfeiffer's syndrome patients.

Hemlock stump. Birch log. September 25th." With notes

[From Jasper Cropsey Sketch book, 1855-1856]

The birch bark roll of woodcraft : The 29th ed. of the manual for boys and girls from 4 to 94 /

Music: p. 82-91.

Secret societies and the French revolution, together with some kindred studies by Una Birch.

Republished from the Edinburgh review and the Nineteenth century and after.