Nueva disposición de sistemas de contención de vehículos en medianas de autovía: New practices for median barriers of highways

La siniestralidad por salida izquierda de vía en carreteras de gran capacidad es un problema que, además de las dramáticas situaciones a las que da lugar, inflige a la sociedad elevados costes. Por ello, debe prestarse una intensa atención al diseño de las medianas y a la disposición de barreras en ellas, con el objetivo de evitar que se produzcan este tipo de accidentes y limitar las consecuencias de los que aún así tengan lugar. Habitualmente las medianas de autovías se diseñan aplicando casi sistemáticamente los parámetros mínimos exigidos normativamente y generalmente con barreras de seguridad adosadas o muy próximas a uno de los arcenes interiores. Sin embargo, tanto las recomendaciones técnicas nacionales como la bibliografía internacional recomiendan llevar a cabo un estudio económico de alternativas antes que colocar barreras y, si está justificada su disposición, alejarla de la calzada disponiéndola próxima al eje de la mediana. En esta tesis se analizan las ventajas y limitaciones que tiene la disposición de barrera próxima al eje de la mediana. Se ha investigado sobre el comportamiento de los vehículos al circular por la mediana y se muestra cómo se ha instalado en la obra de la autovía A‐40, Tramo: Villarrubia de Santiago‐Santa Cruz de la Zarza, destacando los aspectos más novedosos y llamativos pero que se ajustan a las mejores prácticas en la materia y también a la normativa de aplicación. ABSTRACT Many dramatic situations are caused by cross‐median traffic accidents which imply high costs for society, both in human and economic terms. It is therefore important that special attention should be paid to the design of highway medians and to the installation of safety barriers so as to avoid these kinds of incidents and to reduce their consequences. Highway median are usually designed with the application of minimum parameters, according to regulations, with the installation of safety barriers against or close to the inside border. However, Spanish technical regulations and international bibliography recommend a prior study to be carried out with the purpose of finding alternatives to this installation of safety barriers and if necessary, the installation of the safety barrier close to the centre of the median. This thesis directs its analysis towards the advantages and restrictions of installing the safety barrier close to the centre of the median. Research has shown vehicle response when within the median and we show the installation of safety barriers in the A‐40 highway stretch: Villarrubia de Santiago – Santa Cruz de la Zarza, highlighting the aspects that should be taken into account as best practices for road safety and technical regulations.

Analysis and Potential of Use of Biomass Energy in Canary Islands, Spain

Biomass has always been associated with the development of the population in the Canary Islands as the first source of elemental energy that was in the archipelago and the main cause of deforestation of forests, which over the years has been replaced by forest fossil fuels. The Canary Islands store a large amount of energy in the form of biomass. This may be important on a small scale for the design of small power plants with similar fuels from agricultural activities, and these plants could supply rural areas that could have self-sufficiency energy. The problem with the Canary Islands for a boost in this achievement is to ensure the supply to the consumer centers or power plants for greater efficiency that must operate continuously, allowing them to have a resource with regularity, quality and at an acceptable cost. In the Canary Islands converge also a unique topography with a very rugged terrain that makes it greater difficult to use and significantly more expensive. In this work all these aspects are studied, giving conclusions, action paths and theoretical potentials.

Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: Role of inactivation

The role of channel inactivation in the molecular mechanism of calcium (Ca2+) channel block by phenylalkylamines (PAA) was analyzed by designing mutant Ca2+ channels that carry the high affinity determinants of the PAA receptor site [Hockerman, G. H., Johnson, B. D., Scheuer, T., and Catterall, W. A. (1995) J. Biol. Chem. 270, 22119–22122] but inactivate at different rates. Use-dependent block by PAAs was studied after expressing the mutant Ca2+ channels in Xenopus oocytes. Substitution of single putative pore-orientated amino acids in segment IIIS6 by alanine (F-1499-A, F-1500-A, F-1510-A, I-1514-A, and F-1515-A) gradually slowed channel inactivation and simultaneously reduced inhibition of barium currents (IBa) by (−)D600 upon depolarization by 100 ms steps at 0.1 Hz. This apparent reduction in drug sensitivity was only evident if test pulses were applied at a low frequency of 0.1 Hz and almost disappeared at the frequency of 1 Hz. (−)D600 slowed IBa recovery after maintained membrane depolarization (1–3 sec) to a comparable extent in all channel constructs. A drug-induced delay in the onset of IBa recovery from inactivation suggests that PAAs promote the transition to a deep inactivated channel conformation. These findings indicate that apparent PAA sensitivity of Ca2+ channels is not only defined by drug interaction with its receptor site but also crucially dependent on intrinsic gating properties of the channel molecule. A molecular model for PAA-Ca2+ channel interaction that accounts for the relationship between drug induced inactivation and channel block by PAA is proposed.

Open randomised study of use of levonorgestrel releasing intrauterine system as alternative to hysterectomy

Objectives: To assess whether the levonorgestrel intrauterine system could provide a conservative alternative to hysterectomy in the treatment of excessive uterine bleeding.

Legal effects of use of innovative equipment at railroad-highway grade crossings on railroad's accident liability. Final report.

Federal Railroad Administration, Office of Safety, Washington, D.C.

Temporary extension of use of dual rates by steamship conferences : report to accompany H. 12751.

Report submitted by Herbert C. Bonner.

Suggested procedures and acceptance limits for assessing the safety and ease of use of driver information systems /

"December 1995."

The Tampa AID line experiment: extent of use and cost. Analytic study.

National Highway Traffic Safety Administration, Office of Alcohol Countermeasures, Washington, D.C.

Determinants of use of special drawing rights by developing nations /

Mode of access: Internet.