The Granada ignimbrite: A compound pyroclastic unit and its relationship with Upper Miocene caldera volcanism in the northern Puna

The Granada ignimbrite, an Upper Miocene volcanic unit from the northern Puna, previously has been interpreted as an extensive ignimbrite (>2300 km(2)) associated with eruptions from the Vilama caldera (trap-door event). On the basis of new data, we revise its correlation and redefine the unit as a compound, high aspect ratio ignimbrite, erupted at approximately 9.8 Ma. Calculated volumes (similar to 100 km(3)) are only moderate in comparison with other large volume (>1000 km(3)) ignimbrites that erupted approximately 2-6 m.y. later in the region (e.g. Vilama, Panizos, Atana). Six new volcanic units are recognized from sequences previously correlated with Granada (only one sourced from the same center). Consequently, the area ascribed to the Granada ignimbrite is substantially reduced (630 km(2)), and links to the Vilama caldera are not supported. Transport directions suggest the volcanic source for the Granada ignimbrite corresponds to vents buried under younger (>= 7.9-5 Ma) volcanic rocks of the Abra Granada volcanic complex. Episodes of caldera collapse at some stage of eruption are likely, though their nature and timing cannot be defined from available data. The eruption of the Granada ignimbrite marks the onset of a phase of large volume (caldera-sourced) volcanism in the northern Puna. (C) 2007 Elsevier Ltd. All rights reserved.

Lessons in hypnotism

A review of I'm Your Man: The Life of Leonard Cohen by Sylvie Simmons.

The regulation and function of the striated muscle activator of rho signaling (STARS) protein

Healthy living throughout the lifespan requires continual growth and repair of cardiac, smooth, and skeletal muscle. To effectively maintain these processes muscle cells detect extracellular stress signals and efficiently transmit them to activate appropriate intracellular transcriptional programs. The striated muscle activator of Rho signaling (STARS) protein, also known as Myocyte Stress-1 (MS1) protein and Actin-binding Rho-activating protein (ABRA) is highly enriched in cardiac, skeletal, and smooth muscle. STARS binds actin, co-localizes to the sarcomere and is able to stabilize the actin cytoskeleton. By regulating actin polymerization, STARS also controls an intracellular signaling cascade that stimulates the serum response factor (SRF) transcriptional pathway; a pathway controlling genes involved in muscle cell proliferation, differentiation, and growth. Understanding the activation, transcriptional control and biological roles of STARS in cardiac, smooth, and skeletal muscle, will improve our understanding of physiological and pathophysiological muscle development and function.

The STARS signaling pathway: a key regulator of skeletal muscle function

During the last decade, the striated muscle activator of Rho signaling (STARS), a muscle-specific protein, has been proposed to play an increasingly important role in skeletal muscle growth, metabolism, regeneration and stress adaptation. STARS influences actin dynamics and, as a consequence, regulates the myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) transcriptional program, a well-known pathway controlling skeletal muscle development and function. Muscle-specific stress conditions, such as exercise, positively regulates, while disuse and degenerative muscle diseases are associated with a downregulation of STARS and its downstream partners, suggesting a pivotal role for STARS in skeletal muscle health. This review provides a comprehensive overview of the known role and regulation of STARS and the members of its signaling pathway, RhoA, MRTF-A and SRF, in skeletal muscle.

Regulation of the STARS signaling pathway in response to endurance and resistance exercise and training

The striated muscle activator of Rho signaling (STARS) protein and members of its downstream signaling pathway, including myocardin-related transcription factor-A (MRTF-A) and SRF, are increased in response to prolonged resistance exercise training but also following a single bout of endurance cycling. The aim of the present study was to measure and compare the regulation of STARS, MRTF-A and SRF mRNA and protein following 10 weeks of endurance training (ET) versus resistance training (RT), as well as before and following a single bout of endurance (EE) versus resistance exercise (RE). Following prolonged training, STARS, MRTF-A and SRF mRNA levels were all increased by similar magnitude, irrespective of training type. In the training-habituated state, STARS mRNA increased following a single-bout RE when measured 2.5 and 5 h post-exercise and had returned to resting level by 22 h following exercise. MRTF-A and SRF mRNA levels were decreased by 2.5, 5, and 22 h following a single bout of RE and EE exercise when compared to their respective basal levels, with no significant difference seen between the groups at any of the time points. No changes in protein levels were observed following the two modes of exercise training or a single bout of exercise. This study demonstrates that the stress signals elicited by ET and RT result in a comparable regulation of members of the STARS pathway. In contrast, a single bout of EE and RE, performed in the trained state, elicit different responses. These observations suggest that in the trained state, the acute regulation of the STARS pathway following EE or RE may be responsible for exercise-specific muscle adaptations.

Os jurados "leigos" : uma antropologia do tribunal do júri

Nesse estudo busco apresentar uma perspectiva além da retórica “a favor” ou “contra” o Júri. A partir da minha pesquisa de campo no Foro de Porto Alegre, trabalho com a hipótese de que apesar de ser pautado como instrumento amplamente democrático e participativo, e que abra um espaço para o sentimento de justiça do leigo, o Tribunal do Júri é estruturado de tal forma a deixar relativamente pouco espaço a qualquer lógica que não seja a do sistema institucional legal. Desse modo, os jurados, que deveriam representar a perspectiva leiga, acabam reproduzindo e reforçando a lógica jurídica. Uma lógica que, por sinal, longe de pender pela absolvição, parece pesar contra o réu. Examino a hierarquia do campo jurídico, buscando, numa visão de dentro para fora, perceber qual a noção de justiça dos jurados e como o fato de existir jurados veteranos interfere no resultado dos julgamentos. Não se trata de encontrar um culpado pelo fato de a lógica do sistema se impor aos jurados leigos, posto que tal situação decorre mais da composição de forças que está presente no campo jurídico, do que da perpetuação na função de jurado. Entretanto, percebe-se que essa longevidade submete os leigos a uma super exposição à hierarquia vigente no Júri, favorecendo, nas palavras de Pierre Bourdieu, a “adesão dos profanos” à lógica jurídica.

Plankton richness and abundance in several different hydrological situations in lakes lateral to a river: a case study in the mouth zone of a tributary into a tropical reservoir.

A descriptive analysis of the responses of plankton from lakes lateral to a river in its mouth zone into a tropical reservoir to water level variations is presented. Three situations were reported: 1) a comparison of species richness and diversity and of algae population abundance in prolonged drought and in periods of connection of lakes to the river, 2) the spatial distribution of abundance and richness of Rotifera species in four isolated water bodies formed by fragmentation of a lateral lake during a period of prolonged drought and in the same areas during a period of integrity as an ecosystem, 3) the variability of total zooplankton and Cladocera densities at the end of the isolation period of a lateral lake and after the recovery of connection with the river and in a year of continuous connection with the lotic ecosystem. Various idiosyncrasies were observed in connected lateral lakes, like the surface hydrologic connectivity, a primary factor in species richness modifcations and a secondary controlling factor of plankton abundance. Underground hydrologic connectivity, through the river[forward arrow] lake water fux during the high-water period and lake [forward arrow] river during drought period, appears to have an important role in richness and abundance variations of planktonic populations in the lake isolated from the river.

La estructura agraria y el campesinado en El Salvador, Guatemala y Honduras

Incluye Bibliografía

Atributos populacionais e produtividade secundária de rotíferos em ambientes lacustres naturais e artificiais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Linguagem, educação e virtualidade: experiências e reflexões

Pós-graduação em Linguística e Língua Portuguesa - FCLAR

Educação em engenharia: aspectos da formação pedagógica para o ensino em Engenharia Elétrica

Pós-graduação em Engenharia Elétrica - FEIS

Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: In vitro study

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O cantor-ator: um estudo sobre a atuação cênica do cantor na ópera

Pós-graduação em Música - IA

Aluga-se meu apego: a história de vida dos anunciantes de classificados

A lógica instantânea da sociedade informacional não permite que a maioria dos meios de comunicação abra espaço para a história de vida das fontes jornalísticas, muito menos das anônimas. A instantaneidade com que os fatos têm de chegar ao receptor não é compatível com o exercício jornalístico que busca a densidade, o aprofundamento das relações sociais. “Aluga-se meu apego: a história de vida dos anunciantes de Classificados” busca apontar uma alternativa para o jornalismo oficial e superficial. Trata-se de um livro-reportagem de perfil que tenta mapear traços e mudanças da identidade dos anônimos, apontando-os como agentes sociais de suas próprias vidas e das vidas alheias. A partir dos preceitos da psicologia social e da antropologia, busca-se definir a identidade como um processo socialmente construído e sujeito a constantes mutações. Embuído dessa premissa, o Jornalismo Literário aparece como opção que permite o aprofundamento na cobertura dos fatos e a contextualização dos fenômenos decorrentes dele. O conteúdo do livro-reportagem possui dez perfis que contam fragmentos da vida, dos anseios e das angústias de anunciantes dos Classificados do Jornal da Cidade de Bauru (SP) que coabitam o município com as fontes oficiais utilizadas pelos jornais mas que, porém, não têm a mesma visibilidade nem são encarados como fundamentais para nossa realidade