Effects of β-(1→3,1→6)-d-glucan and density of diets on the blood profiles of immunologically challenged weaned piglets

An experiment was conducted to evaluate the effects of two levels of the β-(1→3,1→6)-d-glucan (0 and 500ppm) from yeast Saccharomyces cerevisiae and two levels of energy (3300 and 3450kcalMEkg(-1)) on the hematological, immunological and, biochemical profiles of thirty-six 21-days-old weaned piglets, challenged with 150μgkg(-1) of BW lipopolysaccharide (LPS) from Escherichia coli serotype 055:B5. The experimental design was a randomized complete block design in a 2×2 factorial arrangement with nine replicates per treatment and, one animal per experimental unit. The data were analyzed in accordance with the multivariate analysis procedure of SAS and, the treatment means of parametric and non-parametric data were compared by Bonferroni's test (P<0.05) and, by Dunn's test (P<0.05), respectively. The data of the blood profiles of alanine aminotransferase, alkaline phosphatase and, creatinine showed that LPS did not cause kidney or liver damage in the animals. The addition of beta-glucan in the diets did not prove the robustness of its effect and biological relevance when provided with low nutrient-density. However, its addition combined with the high-nutrient-density diets showed less marked hypoglobulinemia in piglets, which may have contributed to the decreasing of the synthesis of inflammatory mediators.

Perilipin-1 in hemodialyzed patients: association with history of coronary heart disease and lipid profile

Perilipin-1 surrounds lipid droplets in both adipocytes and in atheroma plaque foam cells and controls access of lipases to the lipid core. In hemodialysis (HD) patients, dyslipidemia, malnutrition, inflammation and atherosclerosis are common. Thirty-six HD patients and 28 healthy volunteers were enrolled into the study. Ten HD patients suffered from coronary heart disease (CHD). Perilipin-1, triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL-C), body mass index, albumin, geriatric nutritional risk index, normalized protein catabolic rate, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) were measured. Perilipin-1 did not differ between HD patients and healthy volunteers. IL-6 and TNF-α were higher in HD patients. The evaluated nutritional markers and the markers of inflammation did not differ between HD patients with high perilipin-1 levels and HD patients with low perilipin-1 levels. Regarding the lipid profile, only HDL-C differed between HD patients with high perilipin-1 levels and HD patients with low perilipin-1 levels, and it was higher in the first subgroup. Perilipin-1 was significantly higher in HD patients without CHD. Perilipin-1 is detectable in the serum of HD patients and it is associated with increased HDL-C and decreased incidence of CHD.

Comparison of fecal culture and F57 real-time polymerase chain reaction for the detection of Mycobacterium avium subspecies paratuberculosis in Swiss cattle herds with a history of paratuberculosis

BACKGROUND: Bovine paratuberculosis is an incurable chronic granulomatous enteritis caused by Mycobacterium avium subspecies paratuberculosis (MAP). The prevalence of MAP in the Swiss cattle population is hard to estimate, since only a few cases of clinical paratuberculosis are reported to the Swiss Federal Food Safety and Veterinary Office each year.Fecal samples from 1,339 cattle (855 animals from 12 dairy herds, 484 animals from 11 suckling cow herds, all herds with a history of sporadic paratuberculosis) were investigated by culture and real-time polymerase chain reaction (PCR) for shedding of MAP. RESULTS: By culture, MAP was detected in 62 of 445 fecal pools (13.9%), whereas PCR detected MAP in 9 of 445 pools (2.0%). All 186 samples of the 62 culture-positive pools were reanalyzed individually. By culture, MAP was grown from 59 individual samples (31.7%), whereas PCR detected MAP in 12 individual samples (6.5%), all of which came from animals showing symptoms of paratuberculosis during the study. Overall, MAP was detected in 10 out of 12 dairy herds (83.3%) and in 8 out of 11 suckling cow herds (72.7%). CONCLUSIONS: There is a serious clinically inapparent MAP reservoir in the Swiss cattle population. PCR cannot replace culture to identify individual MAP shedders but is suitable to identify MAP-infected herds, given that the amount of MAP shed in feces is increasing in diseased animals or in animals in the phase of transition to clinical disease

Na 1 Nachlass Max Horkheimer, 695 - "The Collapse of German Democracy and the Expansion of National Socialism", "Cultural Aspects of National Socialism" u.a. (p. IX 169.1a - IX 170.1-4)

"The Collapse of German Democracy and the Expansion of National Socialism" (1940):; 1. Darstellung des Forschungsprojekts (15.9.1940), b. Typoskript mit handschriftlichen Korrekturen, 78 Blatt; 2. "Research work on recent trends in the history of ideas (parts of the Research project on the Collapse of German Democracy would be included)". Als Memorandum zur Eröffnung zur Eröffnung einer Zweigstelle des Instituts in Los Angeles (12.12.1940): a) Typoskript, 2 Blatt, b) Teilstück, Typoskript mit handschriftlichen Korrekturen, 1 Blatt, c) Teilstück, Typoskript mit handschriftlichen Korrekturen, 1 Blatt, d) Teilstück, Typoskript, 1 Blatt, e) Teilstück, Typoskript, 1 Blatt, f) Entwurf, Typoskript mit handschriftlichen Korrekturen und Manuskript, 3 Blatt; 3. University of California, Los Angeles: 2 Briefe (Abschrift) von Max Horkheimer, o.O., 1940, 2 Briefe (Abschrift) an Max Horkheimer, 1940, 2 Blatt; A.R.L. Gurland: "Survey of Structural Changes in the German Economy, 1933 to 1939. Technological Bases and Organizational Forms of the National Socialist Economic System". Typoskript mit handschriftlichen Korrekturen unter anderem von Theodor W. Adorno, 48 Blatt (formal nicht identisch mit "Technological Trends and Economic Structure under National Socialism", Studies in Philosophy and Social Science, Bd. IX, 1941, S. 226ff.); "Cultural Aspects of National Socialism. A Research Project" (1941):; 1. Institute of Social Research: Mitteilung über das Forschungsprojekt und das 'Supplementary Statement', Typoskript, englisch, 4 Blatt; 2. Supplementary Statement to the Research Project, a) Typoskript, 14.4.1941, 63 Blatt, b) Typoskript, 12.4.1941, mit handschriftlichen Korrekturen, 35 Blatt; 3. "Cultural Aspects of National Socialism. A Research Project" (24.2.1941), a) als Typoskript vervielfältigt, 54 Blatt, b) Typoskript mit handschriftlichen Korrekturen, 34 Blatt, c) Fassung Januar 1941, Typoskript mit handschriftlichen Korrekturen, 40 Blatt; 4. Inhaltsverzeichnisse, mit handschriftlichen Korrekturen, 3 Blatt;

Na 1 Nachlass Max Horkheimer, 699 - Cultural Aspects of National Socialism. A Research Project (p. IX 170.15-17a - IX 170.19)

Neumann, Franz: Memorandum über Gespräche mit Harold Lasswell. 30.03.1941, Typoskript mit handschriftlichen Korekturen, 4 Blatt; Neumann, Franz: Memorandum über Gespräche mit Goodvin Watson. 21.05.1941, Typoskript, 2 Blatt; [Anderson, Eugene N.:] "Professor Anderson's Notes and criticisms to the project of German society and culture". Typoskript, 7 Blatt; "Budget for the proposed Research Project of Cultural Aspects of National Socialism". Handschriftliche Notizen, 1 Blatt; Institut of Social Research: Brief an Rockefeller Foundation, New York, 24.06.1941 verschiedene Typoskripte, zum Teil mit handschriftlichen Korrekturen, circa 35 Blatt; ein Manuskript, 6 Blatt; ein Entwurf, Typoskript, 1 Blatt; Adorno, Theodor W.: 2 Briefe an I. Berlin, ohne Ort, 1940-1941; Empfehlungsschreiben zur Unterstützung des Projekts, von: Lutz, Ralph H.: 1 Brief (Abschrift) an Frederick Pollock, 11.07.1941; MacIver, Robert M.: 1 Brief (Abschrift): an New York Foundation, ohne Ort, 07.07.1941; Shotwell, James T.: 1 Brief (Abschrift) an Frederick Pollock, Woodstock, 08.07.1941; Radin, MAx: 1 Brief (Abschrift) an New York Foundation, [Los Angeles], 08.07-1941; 5 Blatt; Antwortbriefe an das Institut bzw. Max Horkheimer aufgrund der Zusendung des Umrisses des Forschungsprojektes, von: Lorwin, Lewis L.; Wooleton, H.; O'Quin, Patricia, Odum, Howard W.; Fay, Sidney B.; Merriam, Charles E.; Hoover, Calvin B.; Garrison, Lloyd K.; März bis Mai 1941, 8 Blatt;

Isaías 24,1-6 na perspectiva da profecia apocalipsista resultante de um complexo processo sócio-teológico em transição

A dissertação objetiva estudar o papel que o apocalipsismo, desempenhou na história e no contexto da redação do oráculo isaiano em Isaías 24,1-6. A proposta é de que sua função foi de grande importância no processo de formação do judaísmo pós-exílico, fomentando uma nova reidentificação e reetnização dos israelitas-judaítas num contexto de frustração nacionalista e religiosa que gerou uma grande heterogeneidade teológica. Identificamos este contexto como sendo o ambiente em que se deu um complexo processo de transição sócio-teológica na história dos judaitas no período de dominação persa. O apocalipsismo, enquanto fenômeno religioso e sócio-histórico, se mostrou como resultado de uma realidade hostil e desumanizadora na qual a identidade teológico-cultural e os relacionamentos sócioeconômicos das pessoas foram extremamente ameaçados e violentados gerando uma contraposição aos desígnios de Yahweh expressos na aliança firmada por ele para com seu povo. Através da pesquisa e análise exegética de Isaías 24,1-6, a presente dissertação propõe que, a partir dessa realidade conflituosa, a profecia apocalipsista isaiana se manifesta contra as estruturas e suas articulações geradoras de segregação e desumanidade, lançando uma esperança no ato transformador por intermédio de Yahweh, o senhor da história, que possibilita um reverso histórico, a partir do qual será possível reconstruir relacionamentos favoráveis no âmbito social e espiritual.(AU)

Isaías 24,1-6 na perspectiva da profecia apocalipsista resultante de um complexo processo sócio-teológico em transição

A dissertação objetiva estudar o papel que o apocalipsismo, desempenhou na história e no contexto da redação do oráculo isaiano em Isaías 24,1-6. A proposta é de que sua função foi de grande importância no processo de formação do judaísmo pós-exílico, fomentando uma nova reidentificação e reetnização dos israelitas-judaítas num contexto de frustração nacionalista e religiosa que gerou uma grande heterogeneidade teológica. Identificamos este contexto como sendo o ambiente em que se deu um complexo processo de transição sócio-teológica na história dos judaitas no período de dominação persa. O apocalipsismo, enquanto fenômeno religioso e sócio-histórico, se mostrou como resultado de uma realidade hostil e desumanizadora na qual a identidade teológico-cultural e os relacionamentos sócioeconômicos das pessoas foram extremamente ameaçados e violentados gerando uma contraposição aos desígnios de Yahweh expressos na aliança firmada por ele para com seu povo. Através da pesquisa e análise exegética de Isaías 24,1-6, a presente dissertação propõe que, a partir dessa realidade conflituosa, a profecia apocalipsista isaiana se manifesta contra as estruturas e suas articulações geradoras de segregação e desumanidade, lançando uma esperança no ato transformador por intermédio de Yahweh, o senhor da história, que possibilita um reverso histórico, a partir do qual será possível reconstruir relacionamentos favoráveis no âmbito social e espiritual.(AU)

Natural history of Victoria. Prodromus of the zoology of Victoria; or, Figures and descriptions of the living species of all classes of the Victorian indigenous animals... By Frederick McCoy...

Decade 6-10

History of the Third division, United States army, in the world war, for the period, December 1, 1917, to January 1, 1919.

Accompanied by 6 maps (53 x 75 1/2 cm folded to 22 x 14 cm)

Illustrated natural history of the animal kingdon, being a systematic and popular description of the habits, structure, and classification of animals from the highest to the lowest forms, with their relation to agriculture, commerce, manufactures, and the arts.

Published in 1868 under title: Johnson's natural history, comprehensive, scientific and popular ...

Illustrated natural history of the animal kingdom, being a systematic and popular description of the habits, structure, and classification of animals from the highest to the lowest forms, with their relations to agriculture, commerce, manufactures, and the arts.

Vol. 1 has added t.-p., illustrated: The animal kingdom illustrated ...

A lecture on the study of ancient coins, in connection with history : as delivered Feb. 6, 1829, in the theatre of the Royal institution of Great Britain--

Engravings of a medal of Mr. Pingo's by T. Trotter mounted opposite p. [1]

Isaías 24,1-6 na perspectiva da profecia apocalipsista resultante de um complexo processo sócio-teológico em transição

A dissertação objetiva estudar o papel que o apocalipsismo, desempenhou na história e no contexto da redação do oráculo isaiano em Isaías 24,1-6. A proposta é de que sua função foi de grande importância no processo de formação do judaísmo pós-exílico, fomentando uma nova reidentificação e reetnização dos israelitas-judaítas num contexto de frustração nacionalista e religiosa que gerou uma grande heterogeneidade teológica. Identificamos este contexto como sendo o ambiente em que se deu um complexo processo de transição sócio-teológica na história dos judaitas no período de dominação persa. O apocalipsismo, enquanto fenômeno religioso e sócio-histórico, se mostrou como resultado de uma realidade hostil e desumanizadora na qual a identidade teológico-cultural e os relacionamentos sócioeconômicos das pessoas foram extremamente ameaçados e violentados gerando uma contraposição aos desígnios de Yahweh expressos na aliança firmada por ele para com seu povo. Através da pesquisa e análise exegética de Isaías 24,1-6, a presente dissertação propõe que, a partir dessa realidade conflituosa, a profecia apocalipsista isaiana se manifesta contra as estruturas e suas articulações geradoras de segregação e desumanidade, lançando uma esperança no ato transformador por intermédio de Yahweh, o senhor da história, que possibilita um reverso histórico, a partir do qual será possível reconstruir relacionamentos favoráveis no âmbito social e espiritual.(AU)

Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia

A prominent feature of several type of cancer is cachexia. This syndrome causes a marked loss of lean body mass and muscle wasting, and appears to be mediated by cytokines and tumour products. There are several proteases and proteolytic pathways that could be responsible for the protein breakdown. In the present study, we investigated whether caspases are involved in the proteolytic process of skeletal muscle catabolism observed in a murine model of cancer cachexia (MAC16), in comparison with a related tumour (MAC13), which does not induce cachexia. Using specific peptide substrates, there was an increase of 54% in the proteolytic activity of caspase-1, 84% of caspase-8, 98% of caspase-3 151% to caspase-6 and 177% of caspase-9, in the gastrocnemius muscle of animals bearing the MAC16 tumour (up to 25% weight loss), in relation to muscle from animals bearing the MAC13 tumour (1-5% weight loss). The dual pattern of 89 kDa and 25 kDa fragmentation of poly (ADP-ribose) polymerase (PARP) occurred in the muscle samples from animals bearing the MAC16 tumour and with a high amount of caspase-like activity. Cytochrome c was present in the cytosolic fractions of gastrocnemius muscles from both groups of animals, suggesting that cytochrome c release from mitochondria may be involved in caspase activation. There was no evidence for DNA fragmentation into a nucleosomal ladder typical of apoptosis in the muscles of either group of mice. This data supports a role for caspases in the catabolic events in muscle involved in the cancer cachexia syndrome. © 2001 Cancer Research Campaign.