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海洋沉积环境中多氯联苯(PCBs)和多环芳烃(PAHs)的研究对于揭示其污染历史、来源途径、迁移转化以及评价其对环境的潜在生态风险都有重要的科学意义和应用价值,本研究选择我国典型近海中比较开阔的南黄海和受人为影响严重的渤海湾沉积物中的PAHs和PCBs作为主要研究对象,结合对生态环境对应关系的剖析,系统研究了沉积物中PAHs和PCBs的地球化学分布特征、影响控制因素、演变趋势、潜在生态风险等,获得了以下系统的认识: 1.南黄海表层沉积物中多环芳烃和多氯联苯的分布与沉积类型及模式相一致,受控于“沉积类型-动力过程-来源途径”。PCBs含量(范围:518~5848 pg/g,平均值:1715 pg/g)低于受人为影响严重的长江口、珠江口和渤海,分布具有中部海区>东部海区>西部海区的特征;PCBs随着沉积物粒径的减小和粘土含量的增加而增加,且与总有机碳(r=0.61,p<0.01)含量呈显著线性正相关,表明PCBs在沉积物中的分布受控于被水动力过程原动力控制的沉积类型与沉积模式。 2. 1914~2004年间,南黄海沉积物中PAHs和PCBs的变化比较显著,在时间序列上经历了三个明显的不同阶段。近90年来,PAHs和PCBs在柱状样中垂直分布随深度的增加而降低,即近年南黄海沉积物中PAHs和PCBs的残留水平比上世纪初明显增加。其中1914~1932年间,PAHs和PCBs保持在较低的水平;1932~1962年间,PAHs和PCBs的含量发生急剧的变化,在1932~1944和1956~1962年两个时间段,PAHs和PCBs的含量达到峰值;自1962年至今,PAHs和PCBs呈稍有增加趋势。PAHs的组成和特征组分比值分析显示,1920~1944年间PAHs主要来自石油产品泄漏,1944~1980年间,主要来自草/木材/煤燃烧,1980年至2004年则显示出石油和燃烧产物混合来源的特征。 3.渤海湾沉积物中的PAHs、PCBs、DDTs和HCHs的分布模式不同,反映了这四种污染物的地球化学行为存在着明显的差异性。PAHs、PCBs、DDTs和HCHs的含量范围为149.0~393.4 ng/g,360.8~1728.3 pg/g,462.2~2007.3 pg/g和4.31~33.8 ng/g。马颊河口、海河口和黄河口附近的海区的沉积物中PAHs和PCBs的含量显著高于渤海湾内其它站位,DDTs在湾外沉积物中的含量大于湾内,在海河口附近站位测得HCHs含量的最高值,在其它站位其浓度变化不大。PAHs特征成分的比值显示渤海湾沉积物中PAHs主要来源于草/木材/煤燃烧的产物经过大气的输运过程进入水体;DDTs和HCHs的组成显示,在DDTs和HCHs被禁用后仍有新的输入源。 4.南黄海沉积物POPs总体水平不高,其环境污染危害和潜在生态风险不大,从沉积物POPs的角度来说南黄海的环境质量较好。潜在生态危害指数评价表明,渤海湾沉积物中芴可能会产生潜在的生态风险,DDTs和HCHs的含量低于一类沉积物质量标准值,总体而言,其沉积物质量良好,潜在生态风险较低。 论文的创新性点在于:1)首次研究了近百年南黄海沉积物中多环芳烃和多氯联苯的演变趋势,判断了其来源并对近百年二者的潜在生态风险进行评价。2)系统剖析了南黄海及渤海湾的生态环境与PAHs和PCBs的耦合关系,对阐明POPs的毒理效应有重要的科学意义。3)系统解析了渤海湾沉积物中PAHs,DDTs和HCHs的污染现状,来源和迁移途径,可为科学开发和利用渤海海域提供重要的理论依据。

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测定了管藻目绿藻刺松藻和假根羽藻的叶状体、叶绿体及类囊体膜的吸收光谱和低温荧光光谱,并同软丝藻等5种非管藻目绿藻和菠菜进行了比较。证实绿藻普遍缺少作为高等植物 PSI 标志的 730nm 的低温长波荧光,其长波发射峰在 710 ~ 715nm 以及 695nm 荧光也不明显。采用和的 PAGE 法从刺松藻、假根羽藻、软丝藻和菠菜中分别得到 11 种、11 种、7 种和 9 种色素蛋白复合物,并测定了各复合物的分子量、Chl a/b、叶绿素的分布、多肽组成和结构关系,以及吸收光谱、低温荧光发射和激发光谱等各种光谱特性。刺松藻和假根羽藻的 CPIa_(1-2) 复合物的荧光发射主峰分别在 698、690 和 685nm,软丝藻 CPIa 在 715nm,菠菜 CPIa_(1-2) 分别在 729 和 722nm。两种管藻目绿藻的 LHCI 与 CII 的结合程度较菠菜和软丝藻更紧密,其 CPI 复合物中仍含有一定量的,710 ~ 715nm 荧光呈隐现状态。用二次 PAGE 法将刺松藻和假根羽藻的 CPIa 和 CIP 再分离,得到 PSI 的捕光复合 LHCI,为管藻黄素-Chl a/b-蛋白复合物, Chl a/b=1.2,含有 27.5、26.2、26 和 24.5kDa 四种多肽,77K 荧光峰在 682 ~ 683nm。LHCI 没有发射高等植物 730nm 荧光的相应组分是管藻目绿藻缺少 730nm 荧光的主要原因。核心复合物 CCI 含有 67 和 56kDa 两种多肽,与软丝藻和菠菜相似,但 3 种藻类核心复合物的 77K 荧光峰在 715nm,而菠菜在 720nm。刺松藻和假根羽藻有 LHCI 存在时,715nm 荧光峰不明显,随着 LHCI 的解离,荧光逐渐显现。刺松藻 PSI 中与 CCI 结合最紧密的是 LHCI 的 27.5 和 24.5kDa 多肽,两个 26 kDa 多肽的结合较为松散。用差速离心法对刺松藻、假根羽藻、软丝藻及菠菜的 PSI 颗粒进行了初步的分离。PSI 粗提物的 77K 长波荧光发射峰分别在 710、712、713 和 730nm,与 PAGE 法得到的结果相符。刺松藻和假根羽藻的 PSII 核心复合物 CPa 与菠菜相同,都含有两个 33kDa 核心多肽及 40 ~ 47 kDa 的内天线蛋白。从两种管藻目绿藻中首次分离到 6 种 LHCII 捕光复合物,其中 LHCP_(1-3),四种都是管藻黄素- Chl a/b-蛋白复合物, Chl a/b=0.7 ~ 0.9。刺松藻和假根羽藻中含量最高、最稳定的捕光复合物是分子量最大的 LHCP_1 由 34.4、31.5、29.5、28.1 和 26.5kDa 多肽构成,其中 34.4 和 31.5kDa 多肽在菠菜和软丝藻中没有对应组分。LHCP_1 再分离结果表明,分子量较小的捕光复合物都是 LHCP_1 的组成部分,但分子量最小的 Fca_1 和 Fca_2 与其它复合物的关系尚不确定。31.5 和 29.5 kDa 多肽是 LHCP_1 的核心,34.4、28.1 和 26.5kDa 多肽位于外侧;整个 LHCP_1 以 28.1 和 26.5kDa 多肽与 CCII 紧密结合,构成 PSII。根据刺松藻和假根羽藻光系统结构及其特异性的研究结果,提出了一个管藻目绿藻 PSI 和 PSII 色素蛋白复合物结构关系模型,并与高等植物的模型做了比较。讨论了光合作用两个光系统结构和特性的进化过程,指出 730nm 低温荧光峰不能作为管藻目乃至非管藻目绿藻 PSI 的表征。管藻目绿藻同杂色藻类在这方面有相似性。

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吕宋海峡黑潮的路径变异和动力机制,一直是学术界十分关注的科学问题,而且此处黑潮对我国南海北部环流以及整个南海海盆的质量和能量平衡都有着重要的影响。本文共分四部分,第一章是综述南海和吕宋海峡黑潮的研究进展和物理海洋中的迟滞现象;第二章是在参数空间Re数与形比参数 (缺口半宽与Munk层厚度的比值),系统研究西边界流的跨跃流态,入侵流态和周期涡旋剥离流态,并确定了上述状态转捩定量关系和转捩曲线。第三章研究经向风场和台风对西边界流的流态的影响,第四章研究西边界流流态处于临界状态时,涡旋扰动源对状态转捩的作用。这些结果用来解释了吕宋海峡黑潮形变的部分结构特征。 在综合考虑缺口宽度、侧摩擦系数和流量的情况下,模式结果显示,在形比参数gama<3.05 时,无论多么小的流量,西边界流都不能进入缺口;当 g<3.05ama<4.31时,较小的流量对应入侵流态,较大的流量对应跨隙流态,并且是一一对应;当 gama>4.31时,相同流量下西边界流可能存在两种稳定态——跨隙流态和入侵流态,由初始态的不同决定;在gama>4.86 时,出现第三种准稳定流态——周期甩涡流态。最后给出了西边界流流态与双参数(gama 和Re)的分岔图和理论分析。 在 和Re数不变的情况下,季风也会使西边界流流态发生改变。实验结果显示,北风有利于西边界流的反气旋入侵,而南风则有利于其跨隙流动。缺口南部海脊对北风的埃克曼输运的阻挡,导致西边界流流量的减小,从而有利于西边界流入侵西海盆。北风在缺口处产生的埃克曼输运对西边界流入侵缺口几乎没有贡献。当西边界流流量远离其流径变化的临界状态时,路径不易受风场的影响。并给出了西边界流流态与双参数(流量和经向风)的分岔图。最后还研究了台风对临界状态西边界流流态的影响。 在西边界流处于临界流态时,涡旋作为扰动源,有可能会导致其流态发生显著转变。当西边界流处于入侵流态的临界状态时,在缺口右侧,无论是反气旋式涡旋还是气旋式涡旋都能促使其发生跨隙流动的转变;而当西边界流处于跨隙流态的临界状态时,在缺口右侧,无论气旋式涡还是反气旋式涡都不能促使其转变为入侵流态。实验还显示涡旋的位置对西边界流流态变化也有很重要的影响,总体来说中尺度涡旋在缺口南侧对西边界流影响最大,在缺口东侧影响次之,而在缺口北侧影响最小。

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Annual variations of egg production rate (EPR) and clutch size of Calanus sinicus, as well as body size of females (prosome length and dry weight), were investigated at a series of stations in the Southern Yellow Sea by onboard incubation. Calanus sinicus was spawning in all the 11 cruises investigated, and the annual variation of EPR was bimodal. Monthly average EPR was highest from May to July, respectively, 5.97, 5.36 and 6.30 eggs female(-1) d(-1), then decreased dramatically to only 1.37 eggs female(-1) d(-1) in August and attained the lowest 1.07 eggs female(-1) d(-1) in October. In November, average EPR increased again to 4.31 eggs female(-1) d(-1). Seasonal variation of clutch size was similar to EPR, except that it decreased gradually after August rather than dramatically as did EPR. Prosome length of females was maximum in May and minimum in October, but dry weight was highest in November. Monthly average EPR correlated better with prosome length than dry weight, while clutch size was rather determined by dry weight of females. It is suggested that egg production of C. sinicus was active during two discontinuous periods when both surface and bottom temperature fell into its favorite range (i.e. 10-23degreesC), and different reproductive strategies were adopted in these two reproductive peaks: other than the highest EPR, longer prosome length was also achieved by C. sinicus from May to July, while females in November developed shorter bodies but accumulated more energy for reproduction.

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通过对格尔木至拉萨段铁路沿线目前生态环境和青藏铁路建设过程中产生的生态环境影响为期21d的调查,初步总结沿线主要植物种382个,主要呈现出5个生态分区,并提出青藏铁路后期建设的建议。

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Based on the 16S mitochondrial partial gene sequences of 29 genera, containing 26 from Oedipodidae and one each from Tanaoceridae, Pyrgomorphidae and Tetrigidae (as outgroups), the homologus sequences were compared and phylogenetic analyses were performed. A phylogenetic tree was inferred by neighbor-joining (NJ). The results of sequences compared show that: (i) in a total of 574 bp of Oedipodidae, the number of substituted nucleotides was 265 bp and the average percentages of T, C, A and G were 38.3%, 11.4%, 31.8% and 18.5%, respectively, and the content of A+T (70.1%) was distinctly richer than that of C+G (29.9%); and (ii) the average nucleotide divergence of 16S rDNA sequences among genera of Oedipodidae were 9.0%, among families of Acridoidea were 17.0%, and between superfamilies (Tetrigoidea and Acridoidea) were 23.9%, respectively. The phylogenetic tree indicated: (i) the Oedipodidae was a monophyletic group, which suggested that the taxonomic status of this family was confirmed; (ii) the genus Heteropternis separated from the other Oedipodids first and had another unique sound-producing structure in morphology, which is the type-genus of subfamily Heteropterninae; and (iii) the relative intergeneric relationship within the same continent was closer than that of different continents, and between the Eurasian genera and the African genera, was closer than that between Eurasians and Americans.

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Ischaemia-related diseases such as peripheral artery disease and coronary heart disease constitute a major issue in medicine as they affect millions of individuals each year and represent a considerable economic burden to healthcare systems. If the underlying ischaemia is not sufficiently resolved it can lead to tissue damage, with subsequent cell death. Treating such diseases remains difficult and several strategies have been used to stimulate the growth of blood vessels and promote regeneration of ischaemic tissues, such as the use of recombinant proteins and gene therapy. Although these approaches remain promising, they have limitations and results from clinical trials using these methods have had limited success. Recently, there has been growing interest in the therapeutic potential of using a cell-based approach to treat vasodegenerative disorders. In vascular medicine, various stem cells and adult progenitors have been highlighted as having a vasoreparative role in ischaemic tissues. This review will examine the clinical potential of several stem and progenitor cells that may be utilised to regenerate defunct or damaged vasculature and restore blood flow to the ischaemic tissue. In particular, we focus on the therapeutic potential of endothelial progenitor cells as an exciting new option for the treatment of ischaemic diseases. © 2012 BioMed Central Ltd

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The purpose of this retrospective cohort study was to identify aspects of caregiving associated with health status among family caregivers in bereavement. Study participants included 151 family caregivers of terminally ill patients who had died, on average, 294 days prior to the study telephone interview. The interview covered two main areas: patient characteristics and caregiver characteristics. Multivariate linear regressions revealed that as the age of the care recipient (regression coefficient [b] = -0.32; 95% confidence interval [CI] -0.48,-0.15) and caregiver (b = -0.14; 95% CI = -0.25, -0.02) increased, caregivers experienced a decline in their physical health during bereavement. Furthermore, caregivers who reported that caregiving interrupted their usual activities (b = -5.97; 95% CI = -9.79, -2.15) had a decline in physical health during bereavement. A poorer mental health status during bereavement was seen in caregivers who reported poor physical health during caregiving (b = -4.31; 95% CI = -8.17, -0.45); and that they received insufficient family support in caregiving (b = -6.01; 95% CI = -9.75, -2.27). It was also revealed that a home death was associated with higher mental health of the caregiver (b = 3.55; 95% CI = 0.26, 6.84). The practice implications of these findings are discussed in this paper.

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Cranberries, high in polyphenols, have been associated with several cardiovascular health benefits, although limited clinical trials have been reported to validate these findings. We tested the hypothesis that commercially available low-energy cranberry juice (Ocean Spray Cranberries, Inc, Lakeville-Middleboro, Mass) will decrease surrogate risk factors of cardiovascular disease, such as lipid oxidation, inflammation, and dyslipidemia, in subjects with metabolic syndrome. In a randomized, double-blind, placebo-controlled trial, participants identified with metabolic syndrome (n = 15-16/group) were assigned to 1 of 2 groups: cranberry juice (480 mL/day) or placebo (480 mL/day) for 8 weeks. Anthropometrics, blood pressure measurements, dietary analyses, and fasting blood draws were conducted at screen and 8 weeks of the study. Cranberry juice significantly increased plasma antioxidant capacity (1.5 ± 0.6 to 2.2 ± 0.4 µmol/L [means ± SD], P <.05) and decreased oxidized low-density lipoprotein and malondialdehyde (120.4 ± 31.0 to 80.4 ± 34.6 U/L and 3.4 ± 1.1 to 1.7 ± 0.7 µmol/L, respectively [means ± SD], P <.05) at 8 weeks vs placebo. However, cranberry juice consumption caused no significant improvements in blood pressure, glucose and lipid profiles, C-reactive protein, and interleukin-6. No changes in these parameters were noted in the placebo group. In conclusion, low-energy cranberry juice (2 cups/day) significantly reduces lipid oxidation and increases plasma antioxidant capacity in women with metabolic syndrome.

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We analyze high temporal and spatial resolution time-series of spectralscans of the Hα line obtained with the CRisp Imaging SpectroPolarimeter instrument mounted on the Swedish Solar Telescope.The data reveal highly dynamic, dark, short-lived structures known asRapid Redshifted and Blueshifted Excursions (RREs, RBEs) that areon-disk absorption features observed in the red and blue wings ofspectral lines formed in the chromosphere. We study the dynamics of RREsand RBEs by tracking their evolution in space and time, measuring thespeed of the apparent motion, line of sight (LOS) Doppler velocity, andtransverse velocity of individual structures. A statistical study oftheir measured properties shows that RREs and RBEs have similaroccurrence rates, lifetimes, lengths, and widths. They also displaynon-periodic, nonlinear transverse motions perpendicular to their axesat speeds of 4-31 km s-1. Furthermore, both typesof structures either appear as high speed jets and blobs that aredirected outwardly from a magnetic bright point with speeds of50-150 km s-1, or emerge within a few seconds. Astudy of the different velocity components suggests that the transversemotions along the LOS of the chromospheric flux tubes are responsiblefor the formation and appearance of these redshifted/blueshiftedstructures. The short lifetime and fast disappearance of the RREs/RBEssuggests that, similar to type II spicules, they are rapidly heated totransition region or even coronal temperatures. We speculate that theKelvin-Helmholtz instability triggered by observed transversemotions of these structures may be a viable mechanism for their heating.

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Background: Multidimensional rehabilitation programmes (MDRPs) have developed in response to the growing number of people living with and surviving cancer. MDRPs comprise a physical component and a psychosocial component. Studies of the effectiveness of these programmes have not been reviewed and synthesised.

Objectives: To conduct a systematic review of studies examining the effectiveness of MDRPs in terms of maintaining or improving the physical and psychosocial well-being of adult cancer survivors.

Search methods: We conducted electronic searches in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL and PsychINFO up to February 2012.

Selection criteria: Selection criteria focused on randomised controlled trials (RCTs) of multidimensional interventions for adult cancer survivors. Interventions had to include a physical component and a psychosocial component and to have been carried out on two or more occasions following completion of primary cancer treatment. Outcomes had to be assessed using validated measures of physical health and psychosocial well-being. Non-English language papers were included.

Data collection and analysis: Pairs of review authors independently selected trials, rated their methodological quality and extracted relevant data. Although meta-analyses of primary and secondary endpoints were planned there was a high level of study heterogeneity and only one common outcome measure (SF-36) could be statistically synthesised. In addition, we conducted a narrative analysis of interventions, particularly in terms of inspecting and identifying intervention components, grouping or categorising interventions and examining potential common links and outcomes.

Main results: Twelve RCTs (comprising 1669 participants) met the eligibility criteria. We judged five studies to have a moderate risk of bias and assessed the remaining seven as having a high risk of bias. It was possible to include SF-36 physical health component scores from five studies in a meta-analysis. Participating in a MDRP was associated with an increase in SF-36 physical health component scores (mean difference (MD) 2.22, 95% confidence interval (CI) 0.12 to 4.31, P = 0.04). The findings from the narrative analysis suggested that MDRPs with a single domain or outcome focus appeared to be more successful than programmes with multiple aims. In addition, programmes that comprised participants with different types of cancer compared to cancer site-specific programmes were more likely to show positive improvements in physical outcomes. The most effective mode of service delivery appeared to be face-to-face contact supplemented with at least one follow-up telephone call. There was no evidence to indicate that MDRPs which lasted longer than six months improved outcomes beyond the level attained at six months. In addition, there was no evidence to suggest that services were more effective if they were delivered by a particular type of health professional.

Authors' conclusions: There is some evidence to support the effectiveness of brief, focused MDRPs for cancer survivors. Rigorous and methodologically sound clinical trials that include an economic analysis are required.

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Partindo da análise de algumas das questões subjacentes à história da educação de infância em Portugal, neste artigo é analisado o processo de profissionalização da/os educadora/es de infância. Nesta análise destaca-se o papel da formação, como factor determinante da história deste grupo profissional, sendo apresentadas as principais etapas desta história. Por fim é feita uma reflexão final sobre a relação entre formação e desenvolvimento profissional. - Starting from the analysis of some of the issues underlying the history of preschool education in Portugal, this article analyzes the process of kindergarten teachers' training. This analysis stresses the key-role of training in this professional group history and presents the main steps of this history. Finally, some final considerations are made about the relation between training and professional development.