Caprine PRNP polymorphisms at codons 171, 211, 222 and 240 in a Greek herd and their association with classical scrapie

The association between PRNP variation and scrapie incidence was investigated in a highly affected Greek goat herd. Four mutations were identified at codons 171Q/R, 211R/Q, 222Q/K and 240P/S. Lysine at codon 222 was found to be associated with the protection from natural scrapie (P=0.0111). Glutamine at codon 211 was observed in eight animals, all of them being scrapie-negative, indicating a possible protective role of this polymorphism although statistical analysis failed to support it (P=0.1074). A positive association (P=0.0457) between scrapie-affected goats and the wild-type Q(171)R(211)Q(222)S(240) allele is presented for the first time. In addition, a novel R(171)RQS allele, which is identical to the A(136)R(154)R(171) allele that has been associated with resistance to classical scrapie in sheep, was observed in low frequency. Resistant alleles that include K(222) and Q(211) are absent or rare in sheep and can provide the basis for the development of a feasible breeding programme for scrapie eradication in goats.

Ms. hebr. oct. 171 - [Sammelband in 2 Teilen: Handschriftenkonvolut]

Vorbesitzer: Eljāqīm Carmoly

Ms. Barth. 171 - Niederländischer Katechismus

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 171 - Glückwunsschreiben von Carl von Knyphausen zum 70. Geburtstag

u.a.: Besuch bei Schopenhauer;

Ms. Praed. 171 - Collectanea et excerpta theologica

Vorbesitzer: Dominikanerkloster Frankfurt am Main

Ms.Ff.F.Stoltze 3. 171 - Brief von Theobald Kerner an Friedrich Stoltze

Übersendung einer "frischgeschossenen Schnepfe"

Raisonnirendes Verzeichniss der H... Z...ischen Gemälde-Sammlung z. Frankfurt am Main : welche Dienstag den 6. April und folgende Tage der Geleitwoche kommender hiesiger Oster-Messe 1819 in der Behausung Lit. C. No. 171, Schäfergasse, nach der Nummern-Folge gegen baare Zahlung öffentlich an den Meistbietenden verkauft werden soll

Sammlung des Herz Zunz

Ms. lat. oct. 171 - Mathematisch-naturkundliche Studienhandschrift

Vorbesitzer: Philipp Jakob Waldschmidt; auf der Spiegelmakulatur wird ein Fridericus Waltschmidt erwähnt.