甲醇对微过氧化酶-11电化学行为的影响

用电化学和圆二色性 (CD)光谱方法比较了不含和含质量分数为 2 0 %甲醇的微过氧化物酶 -1 1 (MP-1 1 )溶液的电化学和电催化性能及结构的差别 .发现加入甲醇使 MP-1 1的电化学反应的可逆性和对 H2 O2 还原的电催化活性增加 ,这是由于加入甲醇使部分双聚的 MP-1 1分子变成单体分子 ,分子的 α-螺旋和 β-转角的结构含量增加 ,无规卷曲的结构含量降低 ,MP-1 1分子中血红素的暴露程度增加而引起的.

Studies on the interaction of porphyrin with antibody with fluorescent spectrum and UV-Vis differential spectra

After meso-tetra (alpha, alpha, alpha, alpha-O-phenylacetyl benzene)porphyrin combined with McAb 1F2, there was a significant hyperchromic effect, indicating that the combination of porphyrin and antibody is rigid and compact, aromatic amino acids exist at the combining sites of antigen in antibody. These aromatic amino acids are Trys and Trps, but the numbers of Trp are more than that found for Trys. The stochiometric ratio of porphyrin to 1F2 is 1:1, the disassociation constant was determined as(2.084+/-0.216) x 10(-10) mol/L by a method of fluorescence quenching, showing that both have a high affinity.

用荧光光谱和紫外-可见差谱研究抗体-卟啉的相互作用

meso-四 (α,α,α,α-O-苯乙酰苯 )卟啉与其单克隆抗体 1 F2结合后 ,产生显著的增色效应 ,反映了卟啉与抗体之间刚性紧密的结合 ,在抗体中的抗原结合部位存在芳香族氨基酸 .用同步荧光光谱结合荧光猝灭法得到抗体抗原结合部位的芳香族氨基酸主要为色氨酸和酪氨酸 ,但酪氨酸的残基数要少于色氨酸 .卟啉与抗体的结合比为 1∶ 1 ,解离常数 (2 .0 84± 0 .2 46)× 1 0 - 1 0 mol/L,可见卟啉与 Mc Ab1 F2有很高的亲和力.

A BIS(2,6-DI-TERT-BUTYL-4-METHYLPHENOLATO)-SAMARIUM(II) COMPLEX, [SM(OAR)2(THF)3]-THF

The title complex, bis(2,6-di-tert-butyl-4-methyl-phenolato-O)tris(tetrahydrofuran-O)samarium tetrahydrofuran solvate, [Sm(C15H23O)2(C4H8O)3].C4H8O, has distorted trigonal bipyramidal geometry around the Sm(II) atom. The 0(2), 0(3) and 0(4) atoms of the

STRUCTURE AND PROPERTIES OF SEQUENTIALLY POLYMERIZED PROPYLENE-B-[ETHYLENE-CO-PROPYLENE]-B-PROPYLENE COPOLYMERS

The structure and properties of presumed block copolymers of polypropylene (PP) with ethylene-propylene random copolymers (EPR), i.e., PP-EPR and PP-EPR-PP, have been investigated by viscometry, transmission electron microscopy, dynamic mechanical analysis, differential scanning calorimetry, gel permeation chromatography, wide-angle x-ray diffraction, and other techniques testing various mechanical properties. PP-EPR and PP-EPR-PP were synthesized using delta-TiCl3-Et2AlCl as a catalyst system. The results indicate that the intrinsic viscosity of these polymers increases with each block-building step, whereas the intrinsic viscosity of those prepared by chain transfer reaction (strong chain-transfer reagent hydrogen was introduced between block-building steps during polymerization) hardly changes with the reaction time. Compared with PP / EPR blends, PP-EPR-PP block copolymers have lower PP and polyethylene crystallinity, and lower melting and crystallization temperatures of crystalline EPR. Two relaxation peaks of PP and EPR appear in the dynamic spectra of blends. They merge into a very broad relaxation peak with block sequence products of the same composition, indicating good compatibility between PP and EPR in the presence of block copolymers. Varying the PP and EPR content affects the crystallinity, density, and morphological structure of the products, which in turn affects the tensile strength and elongation at break. Because of their superior mechanical properties, sequential polymerization products containing PP-EPR and PP-EPR-PP block copolymers may have potential as compatibilizing agents for isotactic polypropylene and polyethylene blends or as potential heat-resistant thermoplastic elastomers.

近2千万年以来东亚季风演化的南海沉积矿物学记录

本论文通过对南海南部ODP1143站和北部ODP1146站两个长柱状沉积物的陆源矿物组成和堆积速率、生物硅含量和堆积速率、粘土矿物组成、结晶学特征、微形貌和化学成分、陆源物质粒度和元素地球化学的综合研究，分析了1143站和1146站的陆源物质来源的演变，分别建立了南海南部和北部的季风演化代用指标，并与黄土、深海风尘沉积、海洋微体古生物记录对比，重建了东亚季风在近20 Ma以来的长期演化，并探讨了青藏高原隆升在季风长期演化中的驱动作用。 地质背景和元素地球化学分析表明ODP1143站的陆源物质主要来自于湄公河的输入。但陆源物质堆积速率、中值粒径、粘土矿物组合、蒙脱石结晶度指数和生物硅含量和堆积速率在5.2 Ma前后的变化表明ODP1143站的湄公河物源在10–5.2 Ma可能受到了越南区域性地壳隆升和玄武岩喷发的影响。而自~5.2 Ma以来，到达ODP1143站的沉积物受湄公河流域内部物源通量所控制。 ODP1146站的陆源物质为多物源、多传输方式供应，并且近20 Ma以来各个物源/传输方式的强度发生了改变。粒度端员组分模拟揭示出，近20 Ma以来风尘平均贡献了20%物质到1146站，河流输入贡献80%。河流输入中，75%来自珠江和台湾，25%来自吕宋岛。1146站的沉积环境、粘土矿物、地球化学分析表明河流输入的石英、长石来自珠江、台湾；蒙脱石主要来自于吕宋岛，高岭石主要来自于珠江，伊利石和绿泥石来自于珠江、台湾、长江。 ODP1146站17–15 Ma间异常高的陆源物质(石英、长石、蒙脱石、高岭石)、生物硅和碳酸盐的堆积速率暗示了在17–15 Ma南海周围地区发生了强烈的构造活动，这可能与南海扩张停止有关。而ODP1146站稀土元素地球化学、粘土矿物结晶学特征在3 Ma以来的明显变化显示近3 Ma以来台湾物质的输入强度显著加强，这可能与3 Ma以来台湾造山活动加强有关。 ODP1143站粘土矿物/长石、高岭石/绿泥石比值和生物硅含量和堆积速率、陆源物质堆积速率的指标组合被用来建立了一个简单的东亚夏季风演化模型。结果显示8.5–7.6 Ma和 7.1–6.2 Ma分别为两个较强的夏季风阶段，在6.2–3.5 Ma为一相对稳定的阶段，然后在3.5–2.5 Ma不断加强，随后从2.5 Ma以来又不断减弱，直到1.0 Ma夏季风强度又再次加强，并且变化幅度和频率加大。 ODP1146站风尘含量、风尘堆积速率、(伊利石+绿泥石)/蒙脱石、(石英+长石)%、陆源物质的平均粒径被用来作为南海北部季风演化的代用指标。研究表明，近20 Ma以来东亚冬季风强度、亚洲内陆干旱程度和冬季风相对夏季风强度在12−9 Ma、8−4 Ma有所加强，在3 Ma以来显著加强。相比而言，夏季风强度在15−3 Ma间比较稳定，在3 Ma可能与冬季风同步加强。 ODP1143站、1146站、1148站的线性沉积速率，以及1143、1146站的总陆源物质、石英、长石和粘土矿物的物质堆积速率在3.5–2.5 Ma的几乎同时增加，代表着对3.5 Ma以来全球气候恶化和东亚夏季风加强的侵蚀响应。青藏高原的阶段性隆升可能促进了东亚季风在8 Ma和3 Ma左右的加强，但两极冰川扩展和全球变冷也是一个可能因素，也可能季风演化是二者共同作用的结果。我们的研究结果倾向于支持青藏高原阶段性隆升在东亚季风长期演化中的驱动作用。

人造虎骨及其生产工艺及应用

本发明涉及一种人造虎骨及其生产工艺及应用，它是下述原料制成：塞隆骨粉、鸡蛋壳粉、磷酸二氢钙、塞隆脂肪油；其生产工艺是将塞隆骨粉、鸡蛋壳粉与磷酸二氢钙混合后，在混合物中添加塞隆脂肪油再添加粘合剂，使用虎骨形模具，将混合物冲压成虎骨形外骨壳，并用塞隆骨粉与塞隆脂肪油混合后作为骨髓添加到外骨壳的髓部即可；其应用是可用人造虎骨代虎骨作虎骨制剂；本发明在化学组成、药效功能和归经、外型与虎骨基本一致，可充分利用塞隆动物资源、并可恢复虎骨制剂；其制备工艺简单、合理。

井间地震速度层析成像方法与软件系统

Crosshole Seismic tomography has been broadly studied and applied in the fields of resource exploration and engineering exploration because of its special observing manner and better resolution than normal seismic exploration. This thesis will state the theory and method of Crosshole Seismic tomography. Basing on the previous studies，the thesis studied the initial velocity model，ray-tracing method, and developed the three-dimension tomography software. All the cells that a ray passes through are of the same velocities if the paths from transmitters to receivers are straight. The cells that the each ray passes through are recorded, and rays that pass through each cell are calculated. The ray average velocity which passes through a cell is set as the cell velocity. Analogously we can make a initial node velocity model because the velocity sum is calculated on the all cells which own to a certain node, and the cell number is summed about each nodes，the ratio of the velocity sum to the all cells number is set as the node velocity. The inversion result from the initial node velocity model is better than that of the average velocity model. Ray-bending and Shortest Path for Rays (SPR) have shortcomings and limitations respectively. Using crooked rays obtained from SPR rather than straight lines as the starting point can not only avoid ray bending converging to the local minimum travel time path, but also settle the no smooth ray problem obtained by SPR. The hybrid method costs much computation time, which is roughly equal to the time that SPR expends. The Delphi development tool based on the Object Pascal language standard has an advantage of object-oriented. TDTOM (Three Dimensions Tomography) was developed by using Delphi from the DOS version. Improvement on the part of inversion was made, which bring faster convergence velocity. TDTOM can be used to do velocity tomography from the first arrival travel time of the seismic wave, and it has the good qualities of friendly user interface and convenient operation. TDTOM is used to reconstruct the velocity image for a set of crosshole data from Karamay Oil Field. The geological explanation is then given by comparing the inversion effects of different ray-tracing methods. High velocity zones mean the cover of oil reservoir, and low velocity zones correspond to the reservoir or the steam flooding layer.

Naive Physics, Event Perception, Lexical Semantics, and Language Acquisition

This thesis proposes a computational model of how children may come to learn the meanings of words in their native language. The proposed model is divided into two separate components. One component produces semantic descriptions of visually observed events while the other correlates those descriptions with co-occurring descriptions of those events in natural language. The first part of this thesis describes three implementations of the correlation process whereby representations of the meanings of whole utterances can be decomposed into fragments assigned as representations of the meanings of individual words. The second part of this thesis describes an implemented computer program that recognizes the occurrence of simple spatial motion events in simulated video input.

Mermera: Non-Coherent Distributed Shared Memory for Parallel Computing

The proliferation of inexpensive workstations and networks has prompted several researchers to use such distributed systems for parallel computing. Attempts have been made to offer a shared-memory programming model on such distributed memory computers. Most systems provide a shared-memory that is coherent in that all processes that use it agree on the order of all memory events. This dissertation explores the possibility of a significant improvement in the performance of some applications when they use non-coherent memory. First, a new formal model to describe existing non-coherent memories is developed. I use this model to prove that certain problems can be solved using asynchronous iterative algorithms on shared-memory in which the coherence constraints are substantially relaxed. In the course of the development of the model I discovered a new type of non-coherent behavior called Local Consistency. Second, a programming model, Mermera, is proposed. It provides programmers with a choice of hierarchically related non-coherent behaviors along with one coherent behavior. Thus, one can trade-off the ease of programming with coherent memory for improved performance with non-coherent memory. As an example, I present a program to solve a linear system of equations using an asynchronous iterative algorithm. This program uses all the behaviors offered by Mermera. Third, I describe the implementation of Mermera on a BBN Butterfly TC2000 and on a network of workstations. The performance of a version of the equation solving program that uses all the behaviors of Mermera is compared with that of a version that uses coherent behavior only. For a system of 1000 equations the former exhibits at least a 5-fold improvement in convergence time over the latter. The version using coherent behavior only does not benefit from employing more than one workstation to solve the problem while the program using non-coherent behavior continues to achieve improved performance as the number of workstations is increased from 1 to 6. This measurement corroborates our belief that non-coherent shared memory can be a performance boon for some applications.

Broadening public input into science policy decision making: can the democratic model for science communication influence scientific, innovation and technological trajectories?

This PhD thesis investigates the potential use of science communication models to engage a broader swathe of actors in decision making in relation to scientific and technological innovation in order to address possible democratic deficits in science and technology policy-making. A four-pronged research approach has been employed to examine different representations of the public(s) and different modes of engagement. The first case study investigates whether patient-groups could represent an alternative needs-driven approach to biomedical and health sciences R & D. This is followed by enquiry into the potential for Science Shops to represent a bottom-up approach to promote research and development of local relevance. The barriers and opportunities for the involvement of scientific researchers in science communication are next investigated via a national survey which is comparable to a similar survey conducted in the UK. The final case study investigates to what extent opposition or support regarding nanotechnology (as an emerging technology) is reflected amongst the YouTube user community and the findings are considered in the context of how support or opposition to new or emerging technologies can be addressed using conflict resolution based approaches to manage potential conflict trajectories. The research indicates that the majority of communication exercises of relevance to science policy and planning take the form of a one-way flow of information with little or no facility for public feedback. This thesis proposes that a more bottom-up approach to research and technology would help broaden acceptability and accountability for decisions made relating to new or existing technological trajectories. This approach could be better integrated with and complementary to government, institutional, e.g. university, and research funding agencies activities and help ensure that public needs and issues are better addressed directly by the research community. Such approaches could also facilitate empowerment of societal stakeholders regarding scientific literacy and agenda-setting. One-way information relays could be adapted to facilitate feedback from representative groups e.g. Non-governmental organisations or Civil Society Organisations (such as patient groups) in order to enhance the functioning and socio-economic relevance of knowledge-based societies to the betterment of human livelihoods.

Spank [at Intimacy: across visceral and digital performance]

Spank follows the journeys of two women as they reveal stories from private and public sources set apart by two centuries. It investigates notions of 'faction' and what is filtered out historically within a theme of female trauma and the body. [ABSTRACT BY THE AUTHOR]