Ellen Evans Cathcart Papers - Accession 238 - M111 (143)

The Ellen Evans Cathcart Papers consist of biographical sketches of Mrs. Ellen Evans Cathcart (1869-1952), first woman member of the Democratic National Committee who was also instrumental in the founding of the Children’s Bureau. Also included in the collection are newspaper clippings, magazine articles, correspondence, reports, certificates, citations, and photographs relating to her work as supervisor of the Children’s Bureau of South Carolina and her involvement in the women’s suffrage movement. Of particular note is an annual report of the South Carolina Council of Defense which outlines the achievements of women of South Carolina in war work and a program book of the 47th annual convention of the National American Woman Suffrage Association.

High prevalence of OXA-143 and alteration of outer membrane proteins in carbapenem-resistant Acinetobacter spp. isolates in Brazil

Carbapenem resistance amongst Acinetobacter spp. has been increasing in the last decade. This study evaluated the outer membrane protein (OMP) profile and production of carbapenemases in 50 carbapenem-resistant Acinetobacter spp. isolates from bloodstream infections. Isolates were identified by API20NE. Minimum inhibitory concentrations (MICs) for carbapenems were determined by broth microdilution. Carbapenemases were studied by phenotypic tests, detection of their encoding gene by polymerase chain reaction (PCR) amplification, and imipenem hydrolysis. Nucleotide sequencing confirming the enzyme gene type was performed using MegaBACE 1000. The presence of OMPs was studied by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) and PCR. Molecular typing was performed using pulsed-field gel electrophoresis (PFGE). All isolates were resistant to carbapenems. Moreover, 98% of the isolates were positive for the gene encoding the enzyme OXA-51-like, 18% were positive for OXA-23-like (only one isolate did not show the presence of the insertion sequence ISAba1 adjacent to this gene) and 76% were positive for OXA-143 enzyme. Five isolates (10%) showed the presence of the IMP-1 gene. Imipenem hydrolysing activity was detected in only three strains containing carbapenemase genes, comprising two isolates containing the bla(IMP) gene and one containing the bla(OXA-51/OXA-23-like) gene. The OMP of 43 kDa was altered in 17 of 25 strains studied, and this alteration was associated with a high meropenem MIC (256 mu g/mL) in 5 of 7 strains without 43 kDa OMP. On the other hand, decreased OMP 33-36 kDa was found in five strains. The high prevalence of OXA-143 and alteration of OMPs might have been associated with a high level of carbapenem resistance. (C) 2012 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

Inhibition of the miR-143/145 cluster attenuated neutrophil differentiation of APL cells

MicroRNAs can influence hematopoietic cell lineage commitment and aberrant expression of hematopoietic miRNAs contributes to AML pathology. We found that miR-143 and miR-145 expression is significantly repressed in primary AML patient samples as compared to neutrophils of healthy donors. Further analysis revealed impaired neutrophil differentiation of APL cells upon inhibition of miR-145 expression. Lastly, we identified p73 as transcriptional regulator of miR-143/145 during neutrophil differentiation of APL cells. Our data suggest that low miR-145 levels in APL, possibly due to aberrant expression of p73 transcription factors, contribute to the differentiation block seen in this disease.

Ms. hebr. oct. 143 - Sefer tagin

Vorbesitzer: Eljāqīm Carmoly; Abraham Merzbacher

Ms. Barth. 143 - Margarita Decreti

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 143 - Anfrage nach der Qualität der Übersetzung des Oupnek'hat von Thaddäus Anselm Rixner 1808

u.a.: Portrait Schopenhauers von der Hermannschen Buchhandlung; Museum Frankfurt; 2. Auflage der Parerga und Paralipomena, Preisschrift Leipziger Fakultät; Immanuel Kant; Friedrich Schleiermacher; Thaddaeus Anselm Rixner;

Ms. Praed. 143 - Manipulus florum

Vorbesitzer: Dominikanerkloster Frankfurt am Main

Ms.Ff.F.Stoltze 3. 143 - Brief von Karl Holthof an Friedrich Stoltze

Demokratischer Verein

Na 1 Nachlass Max Horkheimer, 675 - Forschungsprojekte über Antisemitismus, Vorurteil, Autorität: Einzeluntersuchungen (p. IX 143)

Institut of Social Research: "Studies in Antisemitism. Volume II: III. American Antisemitic Agitators"; enthält: Studien über Martin Luther Thomas, Georg Allison Phelps und 'Conversations with Antisemitis'; Typoskript, gebunden, 436 Blatt;