Opponent appetitive-aversive neural processes underlie predictive learning of pain relief.

Termination of a painful or unpleasant event can be rewarding. However, whether the brain treats relief in a similar way as it treats natural reward is unclear, and the neural processes that underlie its representation as a motivational goal remain poorly understood. We used fMRI (functional magnetic resonance imaging) to investigate how humans learn to generate expectations of pain relief. Using a pavlovian conditioning procedure, we show that subjects experiencing prolonged experimentally induced pain can be conditioned to predict pain relief. This proceeds in a manner consistent with contemporary reward-learning theory (average reward/loss reinforcement learning), reflected by neural activity in the amygdala and midbrain. Furthermore, these reward-like learning signals are mirrored by opposite aversion-like signals in lateral orbitofrontal cortex and anterior cingulate cortex. This dual coding has parallels to 'opponent process' theories in psychology and promotes a formal account of prediction and expectation during pain.

Subcellular localization and inductive expression of the dsRNA-dependent protein kinase PKR from Japanese flounder, Paralichthys olivaceus

The double-stranded RNA (dsRNA)-dependent protein kinase (PKR) belongs to the eIF2 alpha kinase family and plays a critical role in interferon (IFN)-mediated antiviral response. Recently, in Japanese flounder (Paralichthys olivaceus), a PKR gene has been identified. In this study, we showed that PoPKR localized to the cytoplasm, and the dsRNA-binding motifs (dsRBMs) played a determinative role in protein localization. In cultured FEC cells, PoPKR was detected at a low level of constitutive expression but was highly induced after treatment with UV-inactivated grass carp hemorrhagic virus, active SMRV and Poly I:C although with different expression kinetics. In flounder, PoPKR was ubiquitously distributed in all tested tissues, and SMRV infection resulted in significant upregulation at mRNA and protein levels. In order to reveal the role of PoPKR in host antiviral response, its expression upon exposure to various inducers was characterized and further compared with that of PoHRI, which is another eIF2 alpha kinase of flounder. Interestingly, expression comparison revealed that all inducers stimulated upregulation of PoHRI in cultured flounder embryonic cells and fish, with a similar kinetics to PoPKR but to a less extent. These results suggest that, during antiviral immune response, both flounder eIF2 alpha kinases might play similar roles and that PoPKR is the predominant kinase. (C) 2009 National Natural Science Foundation of China and Chinese Academy of Sciences. Published by Elsevier Limited and Science in China Press. All rights reserved.

Calibration of alkenone unsaturation index with growth temperature for a lacustrine species, Chrysotila lamellosa (Haptophyceae)

Although long chain alkenones (LCKs) occur widely in lacustrine sediments, their origin is not clear. Here, we report a lacustrine source, the non-calcifying species Chrysotila lamellosa Anand (Haptophyceae), collected and isolated from an inland saline water body, Lake Xiarinur (Inner Mongolia, China). Its alketione pattern is similar to those of coastal marine strains of C lamellosa,but the relationship between U-37(K') index and culture temperature for the lacustrine species is quite different from that of the coastal species. A significant feature of the alkenones in this strain of C lamellosa is a lack of C-38 methyl alkenones, which might be used to distinguish the species from the marine haptophyte species Emiliania huxleyi and Gephyrocapsa oceanica. The higher C-38 tetraunsaturated compound abundance might be another important feature for distinguishing the C lamellosa alkenone producer from the coastal species Isochrysis galbana. This alkenone distribution pattern has been detected in many lakes, which suggests that C lamellosa or a closely related species might be a very common alkenone precursor in lacustrine systems. We examined U-37(K') and U-37(K) values for C lamellosa as a function of culture temperature in a batch culture experiment. The calibration for U-37(K') vs. culture temperature (T) was U-37(K') = 0.0011 x T-2 - 0.0157 x T + 0.1057(n = 14, r(2) = 0.99) from 10 degrees C to 22 degrees C or U-37(K') = 0.0257 x T - 0.2608(n = 9, r(2) = 0.97) from 14 degrees C to 22 degrees C. U-37(K) vs. culture temperature was U-37(K) = 0 0377 x T - 0.5992(n = 14, r(2) = 0.98) from 10 degrees C to 22 degrees C. Our experiments show that the alkenone unsaturation index (U-37(K')) is strongly controlled by culture temperature and can be used for palaeoclimate reconstruction. (C) 2007 Elsevier Ltd. All rights reserved.

可用带宽度量系统中的若干基本问题

结合过去3年中设计、开发和部署BNeck系统的经验，分析了13个可用带宽度量系统的工作原理及软件实现，并在此基础上总结了可用带宽度量系统中存在的若干基本问题，对这些问题的研究，不仅有利设计和开发出高效、准确的度量系统，也有利于推动网络管理和视频通信等多个相关领域的共同发展。

A semiconductor laser suitably fabricated by planar technology

The semiconductor microlasers with an equilateral triangle resonator which can be fabricated by dry etching technique from the laser wafer of the edge emitting laser, are analyzed by FDTD technique and rate equations. The results show that ETR microlaser is suitable to realize single mode operation. By connecting an output waveguide to one of the vertices of the ETR, we still can get the confined modes with high quality factors. The EM microlasers are potential light sources for photonic integrated circuits.

Magnetic properties of Jiaxian red clay sequences from northern Chinese Loess Plateau and its paleoclimatic significance

IEECAS SKLLQG

Tectonic uplift in the northern Tibetan Plateau since 13.7 Ma ago inferred from molasse deposits along the Altyn Tagh Fault

IEECAS SKLLQG

黄土丘陵沟壑区不同降水年型下土壤水分动态

采用定位监测法,对黄土丘陵沟壑区不同降水年型下旱农坡地、刺槐林、沙棘灌丛和白羊草地土壤水分的时空变化规律进行了分析.结果表明,降水年型对研究区不同植被类型土壤水分的季节变化和剖面垂直变化均有一定影响.旱农坡地平水年土壤水分的季节变化平缓;枯水年雨季前土壤水分缓慢减小,雨季后显著增加;丰水年则整体增加,且雨季后增加明显.刺槐林、沙棘灌丛和白羊草地平水年土壤水分的季节变化表现为整体降低;枯水年沙棘灌丛土壤水分先减后增,刺槐林与白羊草地呈"W"型曲线变化,两个最低值均出现在6月和8月;丰水年沙棘灌丛和刺槐林土壤水分的季节变化呈"V"型,白羊草地的波动较大,最低值出现在8月.旱农坡地枯水年的土壤水分活跃层和次活跃层深度较平水年下移,丰水年次活跃层消失;丰水年和枯水年,刺槐林和白羊草地土壤水分活跃层深度均较平水年下移,沙棘灌丛则上移.

塔克拉玛干沙漠腹地人工绿地土壤中微生物的生态分布及其与土壤因子间的关系

对咸水灌溉条件下的塔克拉玛干沙漠腹地人工绿地土壤微生物的分布规律和环境因子对土壤微生物分布的影响进行了研究 .结果表明 ,人工绿地建成后 ,土壤结构和养分状况得到改善 ,土壤微生物在时间和地域分布上呈现明显的规律性 .土壤微生物区系组成中 ,细菌占绝对优势 ,放线菌次之 ,真菌最少 ;表层微生物数量远多于下层土壤 ;林地外围距林缘近的土壤微生物数量较多 ,3m以外微生物数量已接近流沙微生物量 ;3类土壤微生物分布具有不同的季节性规律 ,且不同立地类型土壤微生物分布差异显著 .土壤速效磷、速效氮、全N对微生物的分布有较大的直接作用 ,通径系数为 1 .0 1～ 2 .58.速效磷 速效钾、有机质 速效钾、速效氮 速效钾、速效氮 效磷速、有机质 速效磷、速效磷 速效氮、全N 速效钾、速效钾 速效磷、全N 速效磷和含水量 速效氮之间的间接作用对微生物影响较明显 ,作用系数为 1 .37～ 2 .58,其余因素的作用相对不显著

涡动相关法与波文比-能量平衡法测算森林蒸散的比较研究——以长白山阔叶红松林为例

分别采用涡动相关法与波文比-能量平衡法(BREB法)测算了长白山阔叶红松林2002年9、10月的森林蒸散量。结果表明,9月,涡动相关法与BREB法测算的森林蒸散量分别为83.1和87.9 mm,后者相对于前者的误差不到6%,且两者日蒸散量有较好的相关性(0.78),表明涡动相关法与BREB法在森林蒸散研究中有很好的一致性。10月,随着秋季落叶,林内水汽压梯度减小。涡动相关法测算的森林蒸散量为42.5 mm,BREB法测算的结果为49.1 mm,后者相对于前者的误差达到了16%,两者日蒸散量相关系数为0.53。在水汽压梯度较小时,BREB法会产生较大误差。9月中上旬,森林主要热量消耗是用于蒸散,约占辐射平衡量的71%;落叶后,森林主要热量消耗变为森林-大气间的感热交换,蒸散耗热只占辐射平衡量的40%。