785 resultados para vision-impaired


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Tesis en inglés. Eliminadas las páginas en blanco del pdf

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[FR] Grande figure de la géographie française —et européenne— du premier quart du XIXe siècle, Conrad Malte-Brun laisse une oeuvre scientifique écrite considérable, dont une vaste Géographie universelle qui marqua alors son époque, rééditée à de multiples reprises durant plus de 50 ans. Contrairement à Élisée Reclus, autre grande figure de la seconde moitié du XIXe siècle, les écrits de Malte-Brun demeurent mal connus, sinon mésestimés. Or, à travers le fil conducteur que représente le chapitre de sa Géographie universelle consacré à l’Espagne, nous avons pour objectif de montrer que son auteur a su dépasser la simple dimension descriptive caractérisant nombre de textes géographiques de son époque pour introduire une réelle dimension explicative. Rien que pour cela, il mérite très largement, à notre sens, d’être redécouvert…

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[EN] Being fish larvae visual feeders, vision plays an important role in larval orientation at first feeding (Blaxter, 1986). Larval trophic behaviour is closely related with the development of the visual capacity, which directly depends on retina organogenesis. In sparids, such as Pagrus major (Kawamura, 1984) and Pagrus auratus (Pankhurst, 1996), the most important changes in the eye structure occur along the lecitotrophic stage as a preparation for prey capture. Neuringer et al.,(1988) has established a critical role for n-3 polyunsaturated fatty acids and, particularly docosahexaenoic acid (DHA) in neural and retinal tissue functions in mammals. Similarly, in larval fish there is a high demand of DHA to form nervous membranes. Bell and Dick (1993) found photoreceptors in the eye, rods and cones accumulate and selectively retain DHA in external segments.Bell et al. (1995) found that feeding juvenile herring a DHA poor Artemia diet during the period of rod development resulted in impaired vision at low light intensities, when rod vision is essential.

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The Ph chromosome is the most frequent cytogenetic aberration associated with adult ALL and it represents the single most significant adverse prognostic marker. Despite imatinib has led to significant improvements in the treatment of patients with Ph+ ALL, in the majority of cases resistance developed quickly and disease progressed. Some mechanisms of resistance have been widely described but the full knowledge of contributing factors, driving both the disease and resistance, remains to be defined. The observation of rapid development of lymphoblastic leukemia in mice expressing altered Ikaros (Ik) isoforms represented the background of this study. Ikaros is a zinc finger transcription factor required for normal hemopoietic differentiation and proliferation, particularly in the lymphoid lineages. By means of alternative splicing, Ikaros encodes several proteins that differ in their abilities to bind to a consensus DNA-binding site. Shorter, DNA nonbinding isoforms exert a dominant negative effect, inhibiting the ability of longer heterodimer partners to bind DNA. The differential expression pattern of Ik isoforms in Ph+ ALL patients was analyzed in order to determine if molecular abnormalities involving the Ik gene could associate with resistance to imatinib and dasatinib. Bone marrow and peripheral blood samples from 46 adult patients (median age 55 yrs, 18-76) with Ph+ ALL at diagnosis and during treatment with imatinib (16 pts) or dasatinib (30 pts) were collected. We set up a fast, high-throughput method based on capillary electrophoresis technology to detect and quantify splice variants. 41% Ph+ ALL patients expressed high levels of the non DNA-binding dominant negative Ik6 isoform lacking critical N-terminal zinc-fingers which display abnormal subcellular compartmentalization pattern. Nuclear extracts from patients expressed Ik6 failed to bind DNA in mobility shift assay using a DNA probe containing an Ikaros-specific DNA binding sequence. In 59% Ph+ ALL patients there was the coexistence in the same PCR sample and at the same time of many splice variants corresponded to Ik1, Ik2, Ik4, Ik4A, Ik5A, Ik6, Ik6 and Ik8 isoforms. In these patients aberrant full-length Ikaros isoforms in Ph+ ALL characterized by a 60-bp insertion immediately downstream of exon 3 and a recurring 30-bp in-frame deletion at the end of exon 7 involving most frequently the Ik2, Ik4 isoforms were also identified. Both the insertion and deletion were due to the selection of alternative splice donor and acceptor sites. The molecular monitoring of minimal residual disease showed for the first time in vivo that the Ik6 expression strongly correlated with the BCR-ABL transcript levels suggesting that this alteration could depend on the Bcr-Abl activity. Patient-derived leukaemia cells expressed dominant-negative Ik6 at diagnosis and at the time of relapse, but never during remission. In order to mechanistically demonstrated whether in vitro the overexpression of Ik6 impairs the response to tyrosine kinase inhibitors (TKIs) and contributes to resistance, an imatinib-sensitive Ik6-negative Ph+ ALL cell line (SUP-B15) was transfected with the complete Ik6 DNA coding sequence. The expression of Ik6 strongly increased proliferation and inhibited apoptosis in TKI sensitive cells establishing a previously unknown link between specific molecular defects that involve the Ikaros gene and the resistance to TKIs in Ph+ ALL patients. Amplification and genomic sequence analysis of the exon splice junction regions showed the presence of 2 single nucleotide polymorphisms (SNPs): rs10251980 [A/G] in the exon2/3 splice junction and of rs10262731 [A/G] in the exon 7/8 splice junction in 50% and 36% of patients, respectively. A variant of the rs11329346 [-/C], in 16% of patients was also found. Other two different single nucleotide substitutions not recognized as SNP were observed. Some mutations were predicted by computational analyses (RESCUE approach) to alter cis-splicing elements. In conclusion, these findings demonstrated that the post-transcriptional regulation of alternative splicing of Ikaros gene is defective in the majority of Ph+ ALL patients treated with TKIs. The overexpression of Ik6 blocking B-cell differentiation could contribute to resistance opening a time frame, during which leukaemia cells acquire secondary transforming events that confer definitive resistance to imatinib and dasatinib.

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[EN]This paper describes a low-cost system that allows the user to visualize different glasses models in live video. The user can also move the glasses to adjust its position on the face. The system, which runs at 9.5 frames/s on general-purpose hardware, has a homeostatic module that keeps image parameters controlled. This is achieved by using a camera with motorized zoom, iris, white balance, etc. This feature can be specially useful in environments with changing illumination and shadows, like in an optical shop. The system also includes a face and eye detection module and a glasses management module.

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[ES]This paper describes some simple but useful computer vision techniques for human-robot interaction. First, an omnidirectional camera setting is described that can detect people in the surroundings of the robot, giving their angular positions and a rough estimate of the distance. The device can be easily built with inexpensive components. Second, we comment on a color-based face detection technique that can alleviate skin-color false positives. Third, a simple head nod and shake detector is described, suitable for detecting affirmative/negative, approval/dissaproval, understanding/disbelief head gestures.

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La tesi tratta i temi di computer vision connessi alle problematiche di inserimento in una piattaforma Web. Nel testo sono spiegate alcune soluzioni per includere una libreria software per l'emotion recognition in un'applicazione web e tecnologie per la registrazione di un video, catturando le immagine da una webcam.

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L'analisi di un'immagine con strumenti automatici si è sviluppata in quella che oggi viene chiamata "computer vision", la materia di studio proveniente dal mondo informatico che si occupa, letteralmente, di "vedere oltre", di estrarre da una figura una serie di aspetti strutturali, sotto forma di dati numerici. Tra le tante aree di ricerca che ne derivano, una in particolare è dedicata alla comprensione di un dettaglio estremamente interessante, che si presta ad applicazioni di molteplici tipologie: la profondità. L'idea di poter recuperare ciò che, apparentemente, si era perso fermando una scena ed imprimendone l'istante in un piano a due dimensioni poteva sembrare, fino a non troppi anni fa, qualcosa di impossibile. Grazie alla cosiddetta "visione stereo", invece, oggi possiamo godere della "terza dimensione" in diversi ambiti, legati ad attività professionali piuttosto che di svago. Inoltre, si presta ad utilizzi ancora più interessanti quando gli strumenti possono vantare caratteristiche tecniche accessibili, come dimensioni ridotte e facilità d'uso. Proprio quest'ultimo aspetto ha catturato l'attenzione di un gruppo di lavoro, dal quale è nata l'idea di sviluppare una soluzione, chiamata "SuperStereo", capace di permettere la stereo vision usando uno strumento estremamente diffuso nel mercato tecnologico globale: uno smartphone e, più in generale, qualsiasi dispositivo mobile appartenente a questa categoria.

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The present work takes into account three posterior parietal areas, V6, V6A, and PEc, all operating on different subsets of signals (visual, somatic, motor). The work focuses on the study of their functional properties, to better understand their respective contribution in the neuronal circuits that make possible the interactions between subject and external environment. In the caudalmost pole of parietal lobe there is area V6. Functional data suggest that this area is related to the encoding of both objects motion and ego-motion. However, the sensitivity of V6 neurons to optic flow stimulations has been tested only in human fMRI experiments. Here we addressed this issue by applying on monkey the same experimental protocol used in human studies. The visual stimulation obtained with the Flow Fields stimulus was the most effective and powerful to activate area V6 in monkey, further strengthening this homology between the two primates. The neighboring areas, V6A and PEc, show different cytoarchitecture and connectivity profiles, but are both involved in the control of reaches. We studied the sensory responses present in these areas, and directly compared these.. We also studied the motor related discharges of PEc neurons during reaching movements in 3D space comparing also the direction and depth tuning of PEc cells with those of V6A. The results show that area PEc and V6A share several functional properties. Area PEc, unlike V6A, contains a richer and more complex somatosensory input, and a poorer, although complex visual one. Differences emerged also comparing the motor-related properties for reaches in depth: the incidence of depth modulations in PEc and the temporal pattern of modulation for depth and direction allow to delineate a trend among the two parietal visuomotor areas.

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Le sujet de cette recherche est la perception chez les voyageurs occidentaux et grecs du XIXᵉ siècle de zones de la Méditerranée depuis toujours point d’intersections culturelles : les villes d’Athènes et de Constantinople. L’objectif de la recherche est de reconstruire la contribution des hommes de lettres, français et grecs, à la constitution de l’identité nationale selon le schéma mis en évidence par Benedict Anderson dans « Communautés Imaginées » On a tenté en se référant au corpus d’identifier dans la littérature de voyage du XIXᵉ siècle, dans le sillage de « Orientalismo » de Edward Said, comment Philhellénisme et Exotisme orientalisant, tous deux d’empreinte romantique, ont contribué à inventer pour Athènes une identité occidentale et pour Istanbul une identité orientale, ignorant presque l’existence entre les deux villes d’une commune matrice byzantine–ottomane ou mieux, l’appartenance commune à l’ensemble géopolitique de la Région Intermédiaire identifiée par Dimitri Kitsikis.

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In recent years, Deep Learning techniques have shown to perform well on a large variety of problems both in Computer Vision and Natural Language Processing, reaching and often surpassing the state of the art on many tasks. The rise of deep learning is also revolutionizing the entire field of Machine Learning and Pattern Recognition pushing forward the concepts of automatic feature extraction and unsupervised learning in general. However, despite the strong success both in science and business, deep learning has its own limitations. It is often questioned if such techniques are only some kind of brute-force statistical approaches and if they can only work in the context of High Performance Computing with tons of data. Another important question is whether they are really biologically inspired, as claimed in certain cases, and if they can scale well in terms of "intelligence". The dissertation is focused on trying to answer these key questions in the context of Computer Vision and, in particular, Object Recognition, a task that has been heavily revolutionized by recent advances in the field. Practically speaking, these answers are based on an exhaustive comparison between two, very different, deep learning techniques on the aforementioned task: Convolutional Neural Network (CNN) and Hierarchical Temporal memory (HTM). They stand for two different approaches and points of view within the big hat of deep learning and are the best choices to understand and point out strengths and weaknesses of each of them. CNN is considered one of the most classic and powerful supervised methods used today in machine learning and pattern recognition, especially in object recognition. CNNs are well received and accepted by the scientific community and are already deployed in large corporation like Google and Facebook for solving face recognition and image auto-tagging problems. HTM, on the other hand, is known as a new emerging paradigm and a new meanly-unsupervised method, that is more biologically inspired. It tries to gain more insights from the computational neuroscience community in order to incorporate concepts like time, context and attention during the learning process which are typical of the human brain. In the end, the thesis is supposed to prove that in certain cases, with a lower quantity of data, HTM can outperform CNN.

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The safe operation of nighttime flight missions would be enhanced using Night Vision Imaging Systems (NVIS) equipment. This has been clear to the military since 1970s and to the civil helicopters since 1990s. In these last months, even Italian Emergency Medical Service (EMS) operators require Night Vision Goggles (NVG) devices that therefore amplify the ambient light. In order to fly with this technology, helicopters have to be NVIS-approved. The author have supported a company, to quantify the potentiality of undertaking the certification activity, through a feasibility study. Even before, NVG description and working principles have been done, then specifications analysis about the processes to make a helicopter NVIS-approved has been addressed. The noteworthy difference between military specifications and the civilian ones highlights non-irrevelant lacks in the latter. The activity of NVIS certification could be a good investment because the following targets have been achieved: Reductions of the certification cost, of the operating time and of the number of non-compliance.

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La tesi si occupa della creazione di una piattaforma virtuale, composta da un sito web e da una applicazione Android, a supporto di persone con handicap motori. La piattaforma e composta da una mappa interattiva che permette agli utenti di inserire nuovi locali o di commentarne esistenti, e di fare lo stesso per le barriere architettoniche. Per questi motivi il progetto e dettato da una continua comunicazione tra client e server, rendendo la piattaforma aggiornata e dinamica, anche alla vista degli utenti. La parte web viene implementata attraverso Spring MVC, utilizzando delle View .jsp ed AJAX per la comunicazione remota con il server. La parte mobile e stata implementata basandosi principalmente sulle classi di geolocalizzazione di Android, oltre alle librerie osmdroid ed osmbonuspack, fornendo compatitiblita con OSM. Questa fornisce anche un servizio di calcolo del percorso, cercando di evitare il numero maggiore di ostacoli. L'applicazione Android appoggia le proprie comunicazioni sulla libreria Robospice. La parte di persistenza e stata implementata adottando un approccio ad alto livello, grazie ad Hibernate e JPA.