Motor Vehicle Crash Fatalities for Week Ending, June 26, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending, June 26, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending, July 3, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending, July 10, 2009

Motor Vehicle Crash Fatalities

Weight status and gender-related differences in motor skills and in child care - based physical activity in young children.

Over the last decades, a decline in motor skills and in physical activity and an increase in obesity has been observed in children. However, there is a lack of data in young children. We tested if differences in motor skills and in physical activity according to weight or gender were already present in 2- to 4-year-old children. Fifty-eight child care centers in the French part of Switzerland were randomly selected for the Youp'là bouge study. Motor skills were assessed by an obstacle course including 5 motor skills, derived from the Zurich Neuromotor Assessment test. Physical activity was measured with accelerometers (GT1M, Actigraph, Florida, USA) using age-adapted cut-offs. Weight status was assessed using the International Obesity Task Force criteria (healthy weight vs overweight) for body mass index (BMI). Of the 529 children (49% girls, 3.4 ± 0.6 years, BMI 16.2 ± 1.2 kg/m2), 13% were overweight. There were no significant weight status-related differences in the single skills of the obstacle course, but there was a trend (p = 0.059) for a lower performance of overweight children in the overall motor skills score. No significant weight status-related differences in child care-based physical activity were observed. No gender-related differences were found in the overall motor skills score, but boys performed better than girls in 2 of the 5 motor skills (p ≤ 0.04). Total physical activity as well as time spent in moderate-vigorous and in vigorous activity during child care were 12-25% higher and sedentary activity 5% lower in boys compared to girls (all p < 0.01). At this early age, there were no significant weight status- or gender-related differences in global motor skills. However, in accordance to data in older children, child care-based physical activity was higher in boys compared to girls. These results are important to consider when establishing physical activity recommendations or targeting health promotion interventions in young children.

Motor Vehicle Crash Fatalities for Week Ending, July 17, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending Revision, July 17, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending, July 24, 2009

Motor Vehicle Crash Fatalities

TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is known as a "death ligand"-a member of the TNF superfamily that binds to receptors bearing death domains. As well as causing apoptosis of certain types of tumor cells, TRAIL can activate both NF-kappaB and JNK signalling pathways. To determine the role of TGF-beta-Activated Kinase-1 (TAK1) in TRAIL signalling, we analyzed the effects of adding TRAIL to mouse embryonic fibroblasts (MEFs) derived from TAK1 conditional knockout mice. TAK1-/- MEFs were significantly more sensitive to killing by TRAIL than wild-type MEFs, and failed to activate NF-kappaB or JNK. Overexpression of IKK2-EE, a constitutive activator of NF-kappaB, protected TAK1-/- MEFs against TRAIL killing, suggesting that TAK1 activation of NF-kappaB is critical for the viability of cells treated with TRAIL. Consistent with this model, TRAIL failed to induce the survival genes cIAP2 and cFlipL in the absence of TAK1, whereas activation of NF-kappaB by IKK2-EE restored the levels of both proteins. Moreover, ectopic expression of cFlipL, but not cIAP2, in TAK1-/- MEFs strongly inhibited TRAIL-induced cell death. These results indicate that cells that survive TRAIL treatment may do so by activation of a TAK1-NF-kappaB pathway that drives expression of cFlipL, and suggest that TAK1 may be a good target for overcoming TRAIL resistance.

Motor Vehicle Crash Fatalities for Week Ending, July 31, 2009

Motor Vehicle Crash Fatalities

Microcréditos y universidad: motor de emprendeduría

El terme microcrèdit és un concepte cada vegada més utilitzat dintre de l'àmbit econòmic i social. Tanmateix, hi ha molts interrogants sobre el que realment són i de l'impacte que poden arribar a ocasionar en la societat. Amb aquesta finalitat, es detallarà què són els microcrèdits, s'explicaran els seus orígens i si el desenvolupament d'aquest tipus de préstecs són sostenibles per part d'una entitat. Així com també, si és possible l’eradicació de la pobresa mitjançant els mateixos. Es durà a terme una breu introducció del concepte microfinances, finalitzant amb una proposta de creació d'un programa de microcrèdit a la cooperació internacional dins de la Universitat Abat Oliba CEU.

Motor Vehicle Crash Fatalities for Week Ending, August 7, 2009

Motor Vehicle Crash Fatalities

Motor Vehicle Crash Fatalities for Week Ending, August 21, 2009

Motor Vehicle Crash Fatalities

Iowa Motor Fuel Tax Monthly Reports, December 2001

The monthly fuel tax report from Iowa Department of Transportation to the Iowa Department of Revenue and Finance.

Iowa Motor Fuel Tax Monthly Reports, November 2001

The monthly fuel tax report from Iowa Department of Transportation to the Iowa Department of Revenue and Finance.