The influence of environmental conditions on immune responses, morphology and recapture probability of nestling house martins (Delichon urbica)

Nestling birds produced later in the season are hypothesized to be of poor quality with a low probability of survival and recruitment. In a Spanish population of house martins (Delichon urbica), we first compared reproductive success, immune responses and morphological traits between the first and the second broods. Second, we investigated the effects of an ectoparasite treatment and breeding date on the recapture rate the following year. Due probably to a reverse situation in weather conditions during the experiment, with more rain during rearing of the first brood, nestlings reared during the second brood were in better condition and had stronger immune responses compared with nestlings from the first brood. Contrary to other findings on house martins, we found a similar recapture rate for chicks reared during the first and the second brood. Furthermore, ectoparasitic house martin bugs had no significant effect on the recapture rate. Recaptured birds had similar morphology but higher immunoglobulin levels when nestlings compared with non-recaptured birds. This result implies that a measure of immune function is a better predictor of survival than body condition per se.

Iowa Department of Corrections, Strategic Plan 2008-2012, October 2008

This report outlines the strategic plan for Iowa Department of Corrections including,goals and mission.

Commission and Division on the Status of Iowans of Asian and Pacific Islander Heritage 2007-2010 Strategic Plan, 2007

This report outlines the strategic plan for Commission and Division on the Status of Iowans of Asian and Pacific Islander Heritage (CAPI) 2007-2010 Strategic Plan including,goals and mission.

Iowa Civil Rights Commission Strategic Plan 2005-2006

This report outlines the strategic plan for Iowa Civil Rights Commission Strategic Plan 2005-2006 including,goals and mission.

Iowa College Student Aid Commission Strategic Plan 2006-2009

This report outlines the strategic plan for Iowa College Student Aid Commissions including,goals and mission.

Iowa Alcoholic Beverages Division, Strategic Plan, 2003

This report outlines the strategic plan for Iowa Alcoholic Beverages Division including, goals and mission.

Iowa Utilities Board, Strategic Plan, 2008

This report outlines the strategic plan for Iowa Utilities Board including, goals and mission.

Assessment of vaccine-induced CD4 T cell responses to the 119-143 immunodominant region of the tumor-specific antigen NY-ESO-1 using DRB1*0101 tetramers.

Abstract: Purpose: NY-ESO-1 (ESO), a tumor-specific antigen of the cancer/testis group, is presently viewed as an important model antigen for the development of generic anticancer vaccines. The ESO119-143 region is immunodominant following immunization with a recombinant ESO vaccine. In this study, we generated DRB1*0101/ESO119-143 tetramers and used them to assess CD4 T-cell responses in vaccinated patients expressing DRB1*0101 (DR1). Experimental Design: We generated tetramers of DRB1*0101 incorporating peptide ESO119-143 using a previously described strategy. We assessed ESO119-143-specific CD4 T cells in peptide-stimulated post-vaccine cultures using the tetramers. We isolated DR1/ESO119-143 tetramer(+) cells by cell sorting and characterized them functionally. We assessed vaccine-induced CD4(+) DR1/ESO119-143 tetramer(+) T cells ex vivo and characterized them phenotypically. Results: Staining of cultures from vaccinated patients with DR1/ESO119-143 tetramers identified vaccine-induced CD4 T cells. Tetramer(+) cells isolated by cell sorting were of T(H)1 type and efficiently recognized full-length ESO. We identified ESO123-137 as the minimal optimal epitope recognized by DR1-restricted ESO-specific CD4 T cells. By assessing DR1/ESO119-143 tetramer(+) cells using T cell receptor (TCR) beta chain variable region (V beta)-specific antibodies, we identified several frequently used V beta. Finally, direct ex vivo staining of patients' CD4 T cells with tetramers allowed the direct quantification and phenotyping of vaccine-induced ESO-specific CD4 T cells. Conclusions: The development of DR1/ESO119-143 tetramers, allowing the direct visualization, isolation, and characterization of ESO-specific CD4 T cells, will be instrumental for the evaluation of spontaneous and vaccine-induced immune responses to this important tumor antigen in DR1-expressing patients

Iowa Commercial Banking, Strategic Plan, 2003

This report outlines the strategic plan for Iowa Alcoholic Beverages Division including, goals and mission.

Iowa Credit Union Division, Strategic Plan, 2008

This report outlines the strategic plan for Credit Union Division including, goals and mission.

Iowa Department of Cultural Affairs, Strategic Plan 2008-2011, 2008

This report outlines the strategic plan for Iowa Department of Cultural Affairs, goals and mission.

Iowa Department of Inspections and Appeals, Strategic Plan 2008-2011, 2008

This report outlines the strategic plan for Iowa Department of Inspections and Appeals, goals and mission.

Iowa Department of Natural Resources, Strategic Plan, 2008

This report outlines the strategic plan for Iowa Department of Natural Resources, goals and mission.

Iowa Department of Management, Strategic Plan, 2008-2011, 2008

This report outlines the strategic plan for Department of Management, goals and mission.

Iowa Department of Transportation, Strategic Plan, 2008-2012, 2008

This report outlines the strategic plan for Department of Transportation, goals and mission.