Nachrichten von dem Leben, Schicksalen und Bekehrung Friedrich Albrecht Augusti, eines vormaligen jüdischen Rabbi, und nachherigen drei und funfzigjährigen christlichen Lehrers

aufgesetzet von Ernst Friedrich Anton Augusti

Exercitatio academica De lingua Ebraea maturius addiscenda

Wittenberg, Univ., Diss., 1733

Treatment of aortic stenosis with a self-expanding transcatheter valve: the International Multi-centre ADVANCE Study.

AIM Transcatheter aortic valve implantation has become an alternative to surgery in higher risk patients with symptomatic aortic stenosis. The aim of the ADVANCE study was to evaluate outcomes following implantation of a self-expanding transcatheter aortic valve system in a fully monitored, multi-centre 'real-world' patient population in highly experienced centres. METHODS AND RESULTS Patients with severe aortic stenosis at a higher surgical risk in whom implantation of the CoreValve System was decided by the Heart Team were included. Endpoints were a composite of major adverse cardiovascular and cerebrovascular events (MACCE; all-cause mortality, myocardial infarction, stroke, or reintervention) and mortality at 30 days and 1 year. Endpoint-related events were independently adjudicated based on Valve Academic Research Consortium definitions. A total of 1015 patients [mean logistic EuroSCORE 19.4 ± 12.3% [median (Q1,Q3), 16.0% (10.3, 25.3%)], age 81 ± 6 years] were enrolled. Implantation of the CoreValve System led to a significant improvement in haemodynamics and an increase in the effective aortic valve orifice area. At 30 days, the MACCE rate was 8.0% (95% CI: 6.3-9.7%), all-cause mortality was 4.5% (3.2-5.8%), cardiovascular mortality was 3.4% (2.3-4.6%), and the rate of stroke was 3.0% (2.0-4.1%). The life-threatening or disabling bleeding rate was 4.0% (2.8-6.3%). The 12-month rates of MACCE, all-cause mortality, cardiovascular mortality, and stroke were 21.2% (18.4-24.1%), 17.9% (15.2-20.5%), 11.7% (9.4-14.1%), and 4.5% (2.9-6.1%), respectively. The 12-month rates of all-cause mortality were 11.1, 16.5, and 23.6% among patients with a logistic EuroSCORE ≤10%, EuroSCORE 10-20%, and EuroSCORE >20% (P< 0.05), respectively. CONCLUSION The ADVANCE study demonstrates the safety and effectiveness of the CoreValve System with low mortality and stroke rates in higher risk real-world patients with severe aortic stenosis.

De autonomia Iudaeorum : commentatio academica ...

Gießen, Univ., Diss. 1739

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial.

The aim of our study was to evaluate the quality of histo- and cytomorphological features of PAXgene-fixed specimens and their suitability for histomorphological classification in comparison to standard formalin fixation. Fifteen colon cancer tissues were collected, divided into two mirrored samples and either formalin fixed (FFPE) or PAXgene fixed (PFPE) before paraffin embedding. HE- and PAS-stained sections were scanned and evaluated in a blinded, randomised ring trial by 20 pathologists from Europe and the USA using virtual microscopy. The pathologists evaluated histological grading, histological subtype, presence of adenoma, presence of lymphovascular invasion, quality of histomorphology and quality of nuclear features. Statistical analysis revealed that the reproducibility with regard to grading between both fixation methods was rather satisfactory (weighted kappa statistic (k w) = 0.73 (95 % confidence interval (CI), 0.41-0.94)), with a higher agreement between the reference evaluation and the PFPE samples (k w = 0.86 (95 % CI, 0.67-1.00)). Independent from preservation method, inter-observer reproducibility was not completely satisfactory (k w = 0.60). Histomorphological quality parameters were scored equal or better for PFPE than for FFPE samples. For example, overall quality and nuclear features, especially the detection of mitosis, were judged significantly better for PFPE cases. By contrast, significant retraction artefacts were observed more frequently in PFPE samples. In conclusion, our findings suggest that the PAXgene Tissue System leads to excellent preservation of histomorphology and nuclear features of colon cancer tissue and allows routine morphological diagnosis.

A critical history of the doctrine of a future life in Israel, in Judaism, and in Christianity or Hebrew, Jewish, and Christian eschatlology from pre-prophetic times till the close of the New Testament Canon, being the first Jowett lectures delivered in 1898-99

R. H. Charles

"Was hat die jüdische Gemeinde Königsbergs König Friedrich I. im besondern zu verdanken?" : Vortrag, gehalten am 15. Januar 1901 im Verein für jüd. Geschichte u. Litteratur zu Königsberg i. Pr.

von Ed. Birnbaum

[Zusätze z. Judenordnung v. Jahre 1749] : ... obwohl i. d. Landtags-Abschiede vom Jahre 1731 u. ... 1739 u. 1749 ... Juden-Ordnungen gegen die zum größten Nachtheil Unserer anderen Unterthanen... ; ... Cassell den 7.ten April 1772, Friedrich L. z. Hessen

Sammelband: enthält 22 Hanauische Juden-Ordnungen; Exlibris von Gottlieb Schnapper-Arndt

Von Staatsbürgern und Bürgern eigenen Sinnes

Infolge der Unabhängigkeitsbewegung Lateinamerikas im frühen 19. Jahrhundert entstanden im Andenraum dei drei Republiken Ecuador, Peru und Bolivien. Der Beitrag untersucht einerseits die Umsetzung des von Vertretern der kreolisch-mestizischen Mehrheitsgesellschaft aus Europa übertragenen Modells des Nationalstaats, andererseits die von der indigenen Bevölkerung entwickelten Vorstellungen und Strategien politischer Partizipation, die verschiedenen Formen der Ablehnung, Übernahme und Umdeutung der nationalstaatlichen Ordnung aufweisen.