Recueil de ballades, rondeaux et bergerettes.

Ces pièces, au nombre de 195, de quarante auteurs différents : Charles d'Orléans, Blosseville, etc., ont été publiées par M. G. Raynaud, pour la Société des anciens textes français, Rondeaux et autres poésies du XVe siècle (Paris, 1889, in-8°). En tête du volume, est le Débat de la Vie et de la Mort ; — à la fin, la copie de quelques rondeaux et couplets, du XVIIIe-XIXe siècle.

Geographic variation in sex-chromosome differentiation in the common frog (Rana temporaria).

In sharp contrast with birds and mammals, sex-determination systems in ectothermic vertebrates are often highly dynamic and sometimes multifactorial. Both environmental and genetic effects have been documented in common frogs (Rana temporaria). One genetic linkage group, mapping to the largest pair of chromosomes and harbouring the candidate sex-determining gene Dmrt1, associates with sex in several populations throughout Europe, but association varies both within and among populations. Here, we show that sex association at this linkage group differs among populations along a 1500-km transect across Sweden. Genetic differentiation between sexes is strongest (FST  = 0.152) in a northern-boreal population, where male-specific alleles and heterozygote excesses (FIS  = -0.418 in males, +0.025 in females) testify to a male-heterogametic system and lack of X-Y recombination. In the southernmost population (nemoral climate), in contrast, sexes share the same alleles at the same frequencies (FST  = 0.007 between sexes), suggesting unrestricted recombination. Other populations show intermediate levels of sex differentiation, with males falling in two categories: some cluster with females, while others display male-specific Y haplotypes. This polymorphism may result from differences between populations in the patterns of X-Y recombination, co-option of an alternative sex-chromosome pair, or a mixed sex-determination system where maleness is controlled either by genes or by environment depending on populations or families. We propose approaches to test among these alternative models, to disentangle the effects of climate and phylogeography on the latitudinal trend, and to sort out how this polymorphism relates to the 'sexual races' described in common frogs in the 1930s.

VOLUMES RELIES du Cabinet des titres : recherches de noblesse, armoriaux, preuves, histoires généalogiques. Armorial universel, du temps de Charles VII.

Incomplet de la fin. — Il y a une table alphabétique des noms ajoutée en tête du volume. — Sur le premier feuillet la signature de Ch. d'Hozier.

Audit Report on Indian Hills Community College in Ottumwa, Iowa for the year ended June 30, 2006

Audit report on Indian Hills Community College in Ottumwa, Iowa for the year ended June 30, 2006.

Cytochrome P-450 activities in human and rat brain microsomes.

The role of cytochrome P450 in the metabolism of dextromethorphan, amitriptyline, midazolam, S-mephenytoin, citalopram, fluoxetine and sertraline was investigated in rat and human brain microsomes. Depending on the parameters, the limit of quantification using gas chromatography-mass spectrometry methods was between 1.6 and 20 pmol per incubation, which generally contained 1500 microg protein. Amitriptyline was shown to be demethylated to nortriptyline by both rat and human microsomes. Inhibition studies using ketoconazole, furafylline, sulfaphenazole, omeprazole and quinidine suggested that CYP3A4 is the isoform responsible for this reaction whereas CYP1A2, CYP2C9, CYP2C19 and CYP2D6 do not seem to be involved. This result was confirmed by using a monoclonal antibody against CYP3A4. Dextromethorphan was metabolized to dextrorphan in rat brain microsomes and was inhibited by quinidine and by a polyclonal antibody against CYP2D6. Only the addition of exogenous reductase allowed the measurement of this activity in human brain microsomes. Metabolites of the other substrates could not be detected, possibly due to an insufficiently sensitive method. It is concluded that cytochrome P450 activity in the brain is very low, but that psychotropic drugs could undergo a local cerebral metabolism which could have pharmacological and/or toxicological consequences.

Avicenna De animalibus ([Reprod.]) / per magistrum Michaelem Scotum de arabico in latinum translatus

Collection : Italian books before 1601 ; 120.10

Opus preclarum melliflui doctoris atque divinorum solertissimi archanonorum exploratoris divi Bernardi abbatis Clarevalensis cantica canticorum multifariam interpretantis ([Reprod.])

Collection : Italian books before 1601 ; 174.4

Liber phisionomiae magistri Michaelis Scoti ([Reprod.])

[Liber physiognomiae (latin). 15..]

Dictionaire, colloques, ou dialogues en quatres langues, Flamen, François, Espaignol et italien ([Reprod.])

Collection : French books before 1601 ; 89.5

Health-Related Quality of Life in patients with hepatitis C in double and triple therapy

Abstract OBJECTIVE Comparing Health-Related Quality of Life (HRQoL) scores in patients with chronic hepatitis C undergoing double and triple antiviral therapy and analyzing possible factors related to HRQoL. METHOD HRQoL was assessed using the Short Form 36 and Chronic Liver Disease Questionnaire, which were applied at baseline and at weeks 4, 12 and 16 of treatment to 32 patients divided into two groups: double therapy with pegylated interferon (IFN-PEG) and ribavirin, and triple therapy with PEG-IFN, ribavirin and telaprevir. RESULTS The reduction of HRQoL was greater in patients receiving triple therapy compared to those treated with two drugs, the most critical time is at 12 weeks in both groups. After removal of telaprevir, the triple therapy group significantly improved their HRQoL scores. Anxiety and depression before treatment, employment status and race are significantly related to diminished HRQoL. CONCLUSION Patients undergoing double and triple therapy have diminished HRQoL indexes, but the addition of telaprevir chooses a more significant decrease.

Phoenix in the Cape Verde Islands

The African Republic of Cape Verde consists of nine inhabited and several uninhabited volcanic islands set out in the Atlantic Ocean, about 500 km off the most westerly point of the African mainland and 1500 km south of the Canary Islands @g. 2). Most are rugged and mountainous; three (Sal, Maio, and Boavista) are flat, desert islands with sand beaches. Precipitation is meagre and very erratic; indeed Cape Verde can be seen as an island extension of the arid Sahel zone. Three species of the genus Phoenix are recorded from the Cape Verde Islands, P. akzctyli&a L., P. canariensis Chabaud and P. atlantica A. Chev. While the former two species have almost certainly been introduced by man, the latter is said to be endemic to the islands. Perhaps because the Cape Verdes are a particularly isolated set of islands or because palms are notoriously awkward to collect, little is known about the taxonomy, origins and natural history of this species. Phoenix atlantica was described by the French botanist Auguste Chevalier (1935a) following field exploration in the Cape Verdes in 1934 (Chevalier 1934: 1153). Chevalier provided limited diagnostic characters, defining the species as a clustering palm with 2-6 trunks, 5-15 m in height with dark green leaves 2-3 m in length. He considered it to be most similar in form to P. &ctyZzjkra and P. canariensis, possessing characters of both (Chevalier 1935a). Chevalier’s description indicates that Phoenix atlantica can be distinguished easily from P. canariensis by its clustering growth form (P. canariensis always has a single, stout trunk) and its shorter, straighter leaves. However, the differences between P. atlantica and P. dactylzjkra appear much more subtle. For example, while P. dacfylifera is usually observed as single-stemmed, when left undisturbed for a number of years it becomes clustering like the Cape Verde Phoenix, so this character on its own is unreliable. Further alleged distinctions include acuminate (P. atlantica) versus rounded (P. dactylzjkra) petals in the male flowers (Chevalier 1935a, b, Greuter 1967: 249, and Brochmann et al. 1997), fruit 2 cm long (P. atlantica) versus fruit more than 2.5 cm long (P. dactyl&a) (Brochmann et al.

Consultoria em Gestão de Recursos Naturais – Áreas Protegidas Santo Antão

Santo Antão é uma das seis ilhas do grupo Barlavento do Arquipélago de Cabo Verde. A morfologia da ilha está fortemente condicionada pela sua natureza vulcânica, pelas formações litológicas dominantes e pelo clima como factor determinante nos processos erosivos antigos e actuais. Na morfologia da ilha destaca-se uma parte central que constitui uma ampla plataforma planáltica de 33 km de extensão no sentido E-W, inserida entre as altitudes 1000 e 1500 m, da qual se erguiam numerosos cones vulcânicos, entre os quais o Tope de Coroa, com 1980 m, que representa o ponto mais alto da ilha. A superfície planáltica central está circundada por duas grandes vertentes, a do lado setentrional (Norte), designadamente, a inclinada para o mar, entalhada profundamente pela rede hidrográfica da qual se destacam as ribeiras Grande, Torre, Paúl e Garça, e a vertente do lado meridional (Sul). Esta última apresenta inclinações moderadas e suaves nas faixas de maiores altitudes e nas zonas litorâneas, respectivamente. As principais formações da vegetação endémica e indígena de Cabo Verde estão, devido a maior riqueza hídrica, relevo e exposição, concentradas na vertente nordeste, apresentando, consequentemente, esta vertente, os melhores quadros paisagísticos da ilha. Nas vertentes sul e noroeste a vegetação é geralmente, menos densa, merecendo, no entanto, algum destaque, as formações vegetais das cabeceiras da Ribeira das Patas, Ribeira Manuel Lopes e locais pontuais do Tope de Coroa. Assim se justifica que cinco (Moroços, Cova, Ribeira da Torre, Ribeira do Paúl e Cruzinha) das seis Áreas Protegidas pertençam à vertente nordeste, estando apenas Tope de Coroa localizada na vertente meridional (Sul).